Quantification of leakage of sub-micron aerosols through surgical masks and facemasks for pediatric use

References

• Food and Drug Administration: Premarket Assessment of Pediatric Medical Devices - Guidance for Industry and Food and Drug Administration Staff. Available at http://www.fda.gov/downloads/MedicalDevices/DeviceRegulationandGuidance/GuidanceDocuments/ucm089742.pdf (accessed November 23, 2016)
   Google Scholar
• Food and Drug Administration: “Masks and N95 Respirators.” Available at http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/GeneralHospitalDevicesandSupplies/PersonalProtectiveEquipment/ucm055977.htm (accessed November 23, 2016).
   Google Scholar
• Radonovich, L.J., Jr., T.M. Perl, V. Davey, and H. Cohen: Preventing the soldiers of health care from becoming victims on the pandemic battlefield: respirators or surgical masks as the armor of choice. Disaster. Med. Publ. Health Prep. 3(Suppl 2):S203–S210 (2009).
   PubMed Web of Science ®Google Scholar
• Food and Drug Administration: “Guidance for Industry and FDA Staff: Surgical Masks - Premarket Notification [510(k)] Submissions; Guidance for Industry and FDA.” Available at http://www.fda.gov/downloads/medicaldevices/deviceregulationandguidance/guidancedocuments/ucm072561.pdf (accessed November 23, 2016).
   Google Scholar
• Center for Disease Control and Prevention: “Ancilliary Respirator Information.” Available at http://www.cdc.gov/niosh/npptl/topics/respirators/disp_part/respsource3additional.html (accessed November 23, 2016).
   Google Scholar
• Patel, R.B., S.D. Skaria, M.M. Mansour, and G.C. Smaldone: Respiratory source control using a surgical mask: an in vitro study. J. Occup. Environ. Hyg. 1–29 (2015).
   PubMed Web of Science ®Google Scholar
• Cowling, B.J., Y. Zhou, D.K. Ip, G.M. Leung, and A.E. Aiello: Face masks to prevent transmission of influenza virus: a systematic review. Epidemiol. Infect. 138(4):449–456 (2010).
   PubMed Web of Science ®Google Scholar
• Gralton, J., and M.L. McLaws: Protecting healthcare workers from pandemic influenza: N95 or surgical masks? Crit. Care Med. 38(2):657–667 (2010).
   PubMed Web of Science ®Google Scholar
• Johnson, D.F., J.D. Druce, C. Birch, and M.L. Grayson: A quantitative assessment of the efficacy of surgical and N95 masks to filter influenza virus in patients with acute influenza infection. Clin. Infect. Dis. 49(2):275–277 (2009).
   PubMed Web of Science ®Google Scholar
• Li, Y., T. Wong, J. Chung, et al.: In vivo protective performance of N95 respirator and surgical facemask. Am. J. Ind. Med. 49(12):1056–1065 (2006).
   PubMed Web of Science ®Google Scholar
• Loeb, M., N. Dafoe, J. Mahony, et al.: Surgical mask vs n95 respirator for preventing influenza among health care workers: a randomized trial. J. Am. Med. Assoc. 302(17):1865–1871 (2009).
   PubMed Web of Science ®Google Scholar
• Seto, W.H., D. Tsang, R.W. Yung, et al.: Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS). Lancet 361(9368):1519–1520 (2003).
   PubMed Web of Science ®Google Scholar
• Bischoff, W.E., T. Reid, G.B. Russell, and T.R. Peters: Transocular entry of seasonal influenza-attenuated virus aerosols and the efficacy of n95 respirators, surgical masks, and eye protection in humans. J. Infect. Dis. 204(2):193–199 (2011).
   PubMed Web of Science ®Google Scholar
• Chen, M., Y.S. Leo, B. Ang, B.H. Heng, and P. Choo: The outbreak of SARS at Tan Tock Seng Hospital–relating epidemiology to control. Ann. Acad. Med. Singapore 35(5):317–325 (2006).
   PubMed Web of Science ®Google Scholar
• Loeb, M., A. McGeer, B. Henry, et al.: SARS among critical care nurses, Toronto. Emerg. Infect. Dis. 10(2):251–255 (2004).
   PubMed Web of Science ®Google Scholar
• Teleman, M.D., I.C. Boudville, B.H. Heng, D. Zhu, and Y.S. Leo: Factors associated with transmission of severe acute respiratory syndrome among health-care workers in Singapore. Epidemiol. Infect. 132(5):797–803 (2004).
   PubMed Web of Science ®Google Scholar
• Rengasamy, S., B.C. Eimer, and J. Szalajda: A quantitative assessment of the total inward leakage of NaCl aerosol representing submicron-size bioaerosol through N95 filtering facepiece respirators and surgical masks. J. Occup. Environ. Hyg. 11(6):388–396 (2014).
   PubMed Web of Science ®Google Scholar
• Lee, S.A., S.A. Grinshpun, and T. Reponen: Respiratory performance offered by N95 respirators and surgical masks: human subject evaluation with NaCl aerosol representing bacterial and viral particle size range. Ann. Occup. Hyg. 52(3):177–185 (2008).
   PubMed Web of Science ®Google Scholar
• Lee, S.A., S.A. Grinshpun, A. Adhikari, et al.: Laboratory and field evaluation of a new personal sampling system for assessing the protection provided by the N95 filtering facepiece respirators against particles. Ann. Occup. Hyg. 49(3):245–257 (2005).
   PubMed Web of Science ®Google Scholar
• Rengasamy, S., and B.C. Eimer: Total inward leakage of nanoparticles through filtering facepiece respirators. Ann. Occup. Hyg. 55(3):253–263 (2011).
   PubMed Web of Science ®Google Scholar
• Rengasamy, S., B.C. Eimer, and J. Szalajda: A quantitative assessment of the total inward leakage of NaCl aerosol representing submicron size bioaerosol through N95 filtering facepiece respirators and surgical masks. J. Occup. Environ. Hyg. 11(6):388–396 (2014).
   Google Scholar
• Institute of Medicine.: “Certifying Personal Protective Technologies: Improving Worker Safety.” Available at http://www.iaff.org/HS/PDF/IOM%20Certifying%20Personal%20Protective%20Technologies%20-%20Improving%20Worker%20Safety.pdf (accessed November 23, 2016)
   Google Scholar
• Guha, S., A. Mejia-Alfaro, P. Hariharan, and M.R. Myers: Effectiveness of facemasks for pediatric populations against submicron-sized aerosols. Am. J. Infect. Control 43(8):871–877 (2015).
   PubMed Web of Science ®Google Scholar
• Lei, Z., and J. Yang: Contact area determination between a N95 filtering facepiece respirator and headform. Dig. Hum. Model. 6777:119–128 (2011).
   Google Scholar
• Grinshpun, S.A., H. Haruta, R.M. Eninger, T. Reponen, R.T. McKay, and S.A. Lee: Performance of an N95 filtering facepiece particulate respirator and a surgical mask during human breathing: two pathways for particle penetration. J. Occup. Environ. Hyg. 6(10):593–603 (2009).
   PubMed Web of Science ®Google Scholar
• Rengasamy, S., G.F. Walbert, W.E. Newcomb, et al.: Total inward leakage measurement of particulates for N95 filtering facepiece respirators–a comparison study. Ann. Occup. Hyg 58(2):206–216 (2014).
   PubMed Web of Science ®Google Scholar
• Coffey, C.C., R.B. Lawrence, D.L. Campbell, Z. Zhuang, C.A. Calvert, and P.A. Jensen: Fitting characteristics of eighteen N95 filtering-facepiece respirators. J. Occup. Environ. Hyg. 1:262–271 (2004).
   PubMed Web of Science ®Google Scholar
• Coffey, C.C., D.L. Campbell, and Z. Zhuang: Simulated Workplace Performance of N95 respirators. Am. Indust. Hyg Assoc. 60(5):618–624 (1999).
   PubMed Web of Science ®Google Scholar
• Zhuang, Z., Bradtmiller, B., and Shaffer, R. E.: New respirator fit test panels representing the current US civilian work force. J. Occup. Environ. Hyg. 4:647–659 (2007).
   PubMed Web of Science ®Google Scholar
• Rengasamy, S., A. Millers, B.C. Eimer, and R.E. Shaffer: Filtration performance of FDA-Cleared Surgical Masks. J. Int. Soc. Respir. Protect. 26:54–70 (2009).
   PubMedGoogle Scholar
• American Society for Testing and Materials: Standard Test Method for Determining the Initial Efficiency of Materials Used in Medical Face Masks to Penetration by Particulates Using Latex Spheres (F2299-03). [Standard] West Conshohocken, PA: ASTM, 2010.
   Google Scholar
• American Society for Testing and Materials: Standard Test Method for Evaluating the Bacterial Filtration Efficiency (BFE) of Medical Face Mask Materials, Using a Biological Aerosol of Staphylococcus aureus (F2101-07). [Standard] West Conshohocken, PA: ASTM, 2007.
   Google Scholar
• Fabian, P., J.J. McDevitt, W.H. DeHaan, et al.: Influenza virus in human exhaled breath: an observational study. PLoS One 3(7):e2691 (2008).
   PubMed Web of Science ®Google Scholar
• Holmgren, H., E. Ljungstrom, A.-C. Almstrand, B. Bake, and A.-C. Oli: Size distribution of exhaled particles in the size range from 0.01 to 2.0 microns. J. Aer. Sci. 41:439–446 (2010).
   Web of Science ®Google Scholar
• Lindsley, W.G., F.M. Blachere, R.E. Thewlis, et al.: Measurements of airborne influenza virus in aerosol particles from human coughs. PLoS One 5(11):e15100 (2010).
   PubMed Web of Science ®Google Scholar
• Rosner, B.: Fundamentals of Biostatistics. Pacific Grove, CA: Duxbury Press, 2000.
   Google Scholar
• Chen, C.-C., and S.-H. Huang: The effects of particle charge on the performance of a filtering facepieces. Am. Indust. Hyg. Assoc. 59:227–233 (1998).
   PubMed Web of Science ®Google Scholar
• Brosseau, L.M.: Fit testing respirators for public health medical emergencies. J. Occup. Environ. Hyg. 7(11):628–632 (2010).
   PubMed Web of Science ®Google Scholar
• Myers, M.R., P. Hariharan, S. Guha, and J. Yan: A mathematical model for assessing the effectiveness of protective devices in reducing risk of infection by inhalable droplets. Math. Med. Biol. DOI: https://doi.org/10.1093/imammb/dqw018 (2016).
   Google Scholar