Maturation of embryonic tissues in a lymph node: a new approach for bioengineering complex organs

References

• Hoppo T, Komori J, Manohar R, Stolz DB, Lagasse E. Rescue of lethal hepatic failure by hepatized lymph nodes in mice. Gastroenterology 2011; 140:656-66.e2; PMID:21070777; http://dx.doi.org/10.1053/j.gastro.2010.11.006
   PubMedGoogle Scholar
• Komori J, Boone L, DeWard A, Hoppo T, Lagasse E. The mouse lymph node as an ectopic transplantation site for multiple tissues. Nat Biotechnol 2012; 30:976-83; PMID:23000933; http://dx.doi.org/10.1038/nbt.2379
   PubMed Web of Science ®Google Scholar
• Francipane MG, Lagasse E. Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1. Oncotarget 2013; 4:1948-62; PMID:24185040
   PubMed Web of Science ®Google Scholar
• Komori J, Deward AD, Gramignoli R, Strom SC, Fontes P, Lagasse E. Potential barriers to human hepatocyte transplantation in MUP-uPARag2gammaC mice. Cell Transplantation 2013; PMID:23998208
   PubMedGoogle Scholar
• Mamber C, Kamphuis W, Haring NL, Peprah N, Middeldorp J, Hol EM. GFAPdelta expression in glia of the developmental and adolescent mouse brain. PLoS One 2012; 7:e52659; PMID:23285135; http://dx.doi.org/10.1371/journal.pone.0052659
   PubMedGoogle Scholar
• Montgomery RA, Dallman MJ. Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol 1991; 147:554-60; PMID:1649220
   PubMed Web of Science ®Google Scholar
• Montgomery RA, Dallman MJ. Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine 1997; 9:717-26; PMID:9344502; http://dx.doi.org/10.1006/cyto.1997.0227
   PubMedGoogle Scholar
• Gordon J, Wilson VA, Blair NF, Sheridan J, Farley A, Wilson L, Manley NR, Blackburn CC. Functional evidence for a single endodermal origin for the thymic epithelium. Nat Immunol 2004; 5:546-53; PMID:15098031; http://dx.doi.org/10.1038/ni1064
   PubMed Web of Science ®Google Scholar
• Rossi SW, Jenkinson WE, Anderson G, Jenkinson EJ. Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature 2006; 441:988-91; PMID:16791197; http://dx.doi.org/10.1038/nature04813
   PubMed Web of Science ®Google Scholar
• Shakib S, Desanti GE, Jenkinson WE, Parnell SM, Jenkinson EJ, Anderson G. Checkpoints in the development of thymic cortical epithelial cells. J Immunol 2009; 182:130-7; PMID:19109143; http://dx.doi.org/10.4049/jimmunol.182.1.130
   PubMed Web of Science ®Google Scholar
• Hamazaki Y, Fujita H, Kobayashi T, Choi Y, Scott HS, Matsumoto M, Minato N. Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Nat Immunol 2007; 8:304-11; PMID:17277780; http://dx.doi.org/10.1038/ni1438
   PubMedGoogle Scholar
• Zuklys S, Balciunaite G, Agarwal A, Fasler-Kan E, Palmer E, Hollander GA. Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol 2000; 165:1976-83; PMID:10925280; http://dx.doi.org/10.4049/jimmunol.165.4.1976
   PubMed Web of Science ®Google Scholar
• Baik S, Jenkinson EJ, Lane PJ, Anderson G, Jenkinson WE. Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors. Eur J Immunol 2013; 43:589-94; PMID:23299414; http://dx.doi.org/10.1002/eji.201243209
   PubMed Web of Science ®Google Scholar
• Ribeiro AR, Rodrigues PM, Meireles C, Di Santo JP, Alves NL. Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo. J Immunol 2013; 191:1200-9; PMID:23794633; http://dx.doi.org/10.4049/jimmunol.1203042
   PubMedGoogle Scholar
• Ohigashi I, Zuklys S, Sakata M, Mayer CE, Zhanybekova S, Murata S, Tanaka K, Hollander GA, Takahama Y. Aire-expressing thymic medullary epithelial cells originate from beta5t-expressing progenitor cells. Proc Natl Acad Sci U S A 2013; 110:9885-90; PMID:23720310; http://dx.doi.org/10.1073/pnas.1301799110
   PubMedGoogle Scholar
• Sun G, Shi YB. Thyroid hormone regulation of adult intestinal stem cell development: mechanisms and evolutionary conservations. Int J Biol Sci 2012; 8:1217-24; PMID:23136549; http://dx.doi.org/10.7150/ijbs.5109
   PubMedGoogle Scholar
• Pinto D, Gregorieff A, Begthel H, Clevers H. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 2003; 17:1709-13; PMID:12865297; http://dx.doi.org/10.1101/gad.267103
   PubMed Web of Science ®Google Scholar
• Spradling A, Drummond-Barbosa D, Kai T. Stem cells find their niche. Nature 2001; 414:98-104; PMID:11689954; http://dx.doi.org/10.1038/35102160
   PubMed Web of Science ®Google Scholar
• Baraniak PR, McDevitt TC. Scaffold-free culture of mesenchymal stem cell spheroids in suspension preserves multilineage potential. Cell Tissue Res 2012; 347:701-11; PMID:21833761; http://dx.doi.org/10.1007/s00441-011-1215-5
   PubMed Web of Science ®Google Scholar
• Langenbach F, Naujoks C, Smeets R, Berr K, Depprich R, Kubler N, Handschel J. Scaffold-free microtissues: differences from monolayer cultures and their potential in bone tissue engineering. Clin Oral Investig 2013; 17:9-17; PMID:22695872; http://dx.doi.org/10.1007/s00784-012-0763-8
   PubMedGoogle Scholar
• Sharma MB, Limaye LS, Kale VP. Mimicking the functional hematopoietic stem cell niche in vitro: recapitulation of marrow physiology by hydrogel-based three-dimensional cultures of mesenchymal stromal cells. Haematologica 2012; 97:651-60; PMID:22058199; http://dx.doi.org/10.3324/haematol.2011.050500
   PubMed Web of Science ®Google Scholar
• Willerth SM, Sakiyama-Elbert SE. Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery. StemBook, ed. The Stem Cell Research Community. Cambridge (MA), 2008
   Google Scholar
• Liu X, Zhang G, Hou C, Wang H, Yang Y, Guan G, Dong W, Gao H, Feng Q. Vascularized bone tissue formation induced by fiber-reinforced scaffolds cultured with osteoblasts and endothelial cells. Biomed Res Int 2013; 2013:854917; PMID:24369019; http://dx.doi.org/10.1155/2013/854917
   PubMedGoogle Scholar
• Rauh J, Milan F, Gunther KP, Stiehler M. Bioreactor systems for bone tissue engineering. Tissue Eng Part B Rev 2011; 17:263-80; PMID:21495897; http://dx.doi.org/10.1089/ten.teb.2010.0612
   PubMed Web of Science ®Google Scholar
• Mabvuure N, Hindocha S, Khan WS. The role of bioreactors in cartilage tissue engineering. Curr Stem Cell Res Ther 2012; 7:287-92; PMID:22563665; http://dx.doi.org/10.2174/157488812800793018
   PubMedGoogle Scholar
• Berry JL, Steen JA, Koudy Williams J, Jordan JE, Atala A, Yoo JJ. Bioreactors for development of tissue engineered heart valves. Ann Biomed Eng 2010; 38:3272-9; PMID:20820920; http://dx.doi.org/10.1007/s10439-010-0148-6
   PubMed Web of Science ®Google Scholar
• Auger FA, Gibot L, Lacroix D. The pivotal role of vascularization in tissue engineering. Annu Rev Biomed Eng 2013; 15:177-200; PMID:23642245; http://dx.doi.org/10.1146/annurev-bioeng-071812-152428
   PubMed Web of Science ®Google Scholar
• Tourneur E, Chassin C. Neonatal immune adaptation of the gut and its role during infections. Clin Dev Immunol 2013; 2013:270301; PMID:23737810; http://dx.doi.org/10.1155/2013/270301
   PubMedGoogle Scholar
• Tsubouchi S, Leblond CP. Migration and turnover of entero-endocrine and caveolated cells in the epithelium of the descending colon, as shown by radioautography after continuous infusion of 3H-thymidine into mice. Am J Anat 1979; 156:431-51; PMID:525623; http://dx.doi.org/10.1002/aja.1001560403
   PubMedGoogle Scholar
• Merani S, Toso C, Emamaullee J, Shapiro AM. Optimal implantation site for pancreatic islet transplantation. Br J Surg 2008; 95:1449-61; PMID:18991254; http://dx.doi.org/10.1002/bjs.6391
   PubMed Web of Science ®Google Scholar
• Bartholomeus K, Jacobs-Tulleneers-Thevissen D, Shouyue S, Suenens K, In't Veld PA, Pipeleers-Marichal M, Pipeleers DG, Hellemans K. Omentum is better site than kidney capsule for growth, differentiation, and vascularization of immature porcine beta-cell implants in immunodeficient Rats. Transplantation 2013; 96(12):1026-33; PMID:24056625; http://dx.doi.org/10.1097/TP.0b013e3182a6ee41
   PubMedGoogle Scholar
• Kim HI, Yu JE, Park CG, Kim SJ. Comparison of four pancreatic islet implantation sites. J Korean Med Sci 2010; 25:203-10; PMID:20119571; http://dx.doi.org/10.3346/jkms.2010.25.2.203
   PubMed Web of Science ®Google Scholar
• Ellis H. The clinical significance of adhesions: focus on intestinal obstruction. Eur J Surg Suppl 1997:5-9
   PubMedGoogle Scholar
• DeWard AD, Komori J, Lagasse E. Ectopic transplantation sites for cell-based therapy. Current opinion in organ transplantation 2014; 19:169-74; PMID:24480968; http://dx.doi.org/10.1097/MOT.0000000000000050
   PubMedGoogle Scholar
• Lawenda BD, Mondry TE, Johnstone PA. Lymphedema: a primer on the identification and management of a chronic condition in oncologic treatment. CA Cancer J Clin 2009; 59:8-24; PMID:19147865; http://dx.doi.org/10.3322/caac.20001
   PubMed Web of Science ®Google Scholar
• Weir GC. Cellular transplantation into lymph nodes may not be such a crazy idea. Cell Stem Cell 2012; 11:587-8; PMID:23122285; http://dx.doi.org/10.1016/j.stem.2012.10.004
   PubMedGoogle Scholar