Circular RNA participates in the carcinogenesis and the malignant behavior of cancer

References

• Salzman J, Gawad C, Wang PL, Lacayo N, Brown PO. Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. PLoS ONE 2012; 7:e30733; PMID:22319583; http://dx.doi.org/10.1371/journal.pone.0030733
   PubMed Web of Science ®Google Scholar
• Wang KS, Choo QL, Weiner AJ, Ou JH, Najarian RC, Thayer RM, Mullenbach GT, Denniston KJ, Gerin JL, Houghton M. Structure, sequence and expression of the hepatitis delta (delta) viral genome. Nature 1986; 323:508–14; PMID:3762705; http://dx.doi.org/10.1038/323508a0
   PubMed Web of Science ®Google Scholar
• Wilusz JE, Sharp, PA. Molecular biology. A circuitous route to noncoding RNA. Science 2013; 340:440–1; PMID:23620042; http://dx.doi.org/10.1126/science.1238522
   PubMed Web of Science ®Google Scholar
• Sanger HL, Klotz G, Riesner D, Gross HJ, Kleinschmidt AK. Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proc Natl Acad Sci U S A 1976; 73:3852–6; PMID:1069269; http://dx.doi.org/10.1073/pnas.73.11.3852
   PubMed Web of Science ®Google Scholar
• Burgess DJ. RNA: Dissecting circular RNA biogenesis. Nat Rev Genet 2014; 15:707; PMID:25352302; http://dx.doi.org/10.1038/nrg3852
   Google Scholar
• Vicens Q, Westhof E. Biogenesis of Circular RNAs. Cell 2014; 159:13–4; PMID:25259915; http://dx.doi.org/10.1016/j.cell.2014.09.005
   PubMed Web of Science ®Google Scholar
• Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, Loewer A. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature 2013; 495:333–8; PMID:23446348; http://dx.doi.org/10.1038/nature11928
   PubMed Web of Science ®Google Scholar
• Hansen TB, Jensen TI, Clausen BH, Bramsen JB, Finsen B, Damgaard CK, Kjems J. Natural RNA circles function as efficient microRNA sponges. Nature 2013; 495:384–8; PMID:23446346; http://dx.doi.org/10.1038/nature11993
   PubMed Web of Science ®Google Scholar
• Hansen TB, Wiklund ED, Bramsen JB, Villadsen SB, Statham AL, Clark SJ, Kjems J. miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA. EMBO J 2011; 30:4414–22; PMID:21964070; http://dx.doi.org/10.1038/emboj.2011.359
   PubMed Web of Science ®Google Scholar
• Fatica A, Bozzoni I. Long non-coding RNAs: new players in cell differentiation and development. Nat Rev Genet 2014; 15:7–21; PMID:24296535; http://dx.doi.org/10.1038/nrg3606
   PubMed Web of Science ®Google Scholar
• Esteller M. Non-coding RNAs in human disease. Nat Rev Genet 2011; 12:861–74; PMID:22094949; http://dx.doi.org/10.1038/nrg3074
   PubMed Web of Science ®Google Scholar
• Suzuki H, Tsukahara T. A view of pre-mRNA splicing from RNase R resistant RNAs. Int J Mol Sci 2014; 15:9331–42; PMID:24865493; http://dx.doi.org/10.3390/ijms15069331
   PubMed Web of Science ®Google Scholar
• Liang D, Wilusz JE. Short intronic repeat sequences facilitate circular RNA production. Genes Dev 2014; 28:2233–47; PMID:25281217; http://dx.doi.org/10.1101/gad.251926.114
   PubMed Web of Science ®Google Scholar
• Zhou H, Arcila ML, Li Z, Lee EJ, Henzler C, Liu J, Rana TM, Kosik KS. Deep annotation of mouse iso-miR and iso-moR variation. Nucleic Acids Res 2012; 40:5864–75; PMID:22434881; http://dx.doi.org/10.1093/nar/gks247
   PubMed Web of Science ®Google Scholar
• Zhang, X.-O., Wang HB, Zhang Y, Lu X, Chen LL, Yang L. Complementary Sequence-Mediated Exon Circularization. Cell 2014; 159:134–147; PMID:25242744; http://dx.doi.org/10.1016/j.cell.2014.09.001
   PubMed Web of Science ®Google Scholar
• Fu Y, Ramisetty SR, Hussain N, Baranger AM. MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation. Chembiochem 2012; 13:112–9; PMID:22106026; http://dx.doi.org/10.1002/cbic.201100487
   PubMed Web of Science ®Google Scholar
• Ashwal-Fluss R, Meyer M, Pamudurti NR, Ivanov A, Bartok O, Hanan M, Evantal N, Memczak S, Rajewsky N, Kadener S. circRNA Biogenesis Competes with Pre-mRNA Splicing. Mol Cell 2014; 56:55–66; PMID:25242144; http://dx.doi.org/10.1016/j.molcel.2014.08.019
   PubMed Web of Science ®Google Scholar
• Szmulewicz MN, Novick GE, Herrera RJ. Effects of Alu insertions on gene function. Electrophoresis 1998; 19:1260–4; PMID:9694261; http://dx.doi.org/10.1002/elps.1150190806
   PubMed Web of Science ®Google Scholar
• Conn SJ, Pillman KA, Toubia J, Conn VM, Salmanidis M, Phillips CA, Roslan S, Schreiber AW, Gregory PA, Goodall GJ. The RNA Binding Protein Quaking Regulates Formation of circRNAs. Cell 2015; 160:1125–34; PMID:25768908; http://dx.doi.org/10.1016/j.cell.2015.02.014
   PubMed Web of Science ®Google Scholar
• Garg M. Targeting microRNAs in epithelial-to-mesenchymal transition-induced cancer stem cells: therapeutic approaches in cancer. Expert Opin Ther Targets 2015; 19:285–97; PMID:25563894; http://dx.doi.org/10.1517/14728222.2014.975794
   PubMed Web of Science ®Google Scholar
• Ye X, Weinberg R A. Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression. Trends Cell Biol 2015; PMID:26437589; http://dx.doi.org/10.1016/j.tcb.2015.07.012
   PubMed Web of Science ®Google Scholar
• Zhang Y, Zhang XO, Chen T, Xiang JF, Yin QF, Xing YH, Zhu S, Yang L, Chen LL. Circular intronic long noncoding RNAs. Mol Cell 2013; 51:792–806; PMID:24035497; http://dx.doi.org/10.1016/j.molcel.2013.08.017
   PubMed Web of Science ®Google Scholar
• Umekage S, Kikuchi Y. In vivo circular RNA production using a constitutive promoter for high-level expression. J Biosci Bioeng 2009; 108:354–6; PMID:19716528; http://dx.doi.org/10.1016/j.jbiosc.2009.04.011
   PubMed Web of Science ®Google Scholar
• Guil S, Esteller M. RNA-RNA interactions in gene regulation: the coding and noncoding players. Trends Biochem Sci 2015; 40:248–56; PMID:25818326
   PubMed Web of Science ®Google Scholar
• Cheng DL, Xiang YY, Ji LJ, Lu XJ. Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives. Tumour Biol 2015; 36:479–88; PMID:25604144; http://dx.doi.org/10.1007/s13277-015-3093-z
   PubMed Web of Science ®Google Scholar
• Satterlee JS, Basanta-Sanchez M, Blanco S, Li JB, Meyer K, Pollock J, Sadri-Vakili G, Rybak-Wolf A. Novel RNA modifications in the nervous system: form and function. J Neurosci 2014; 34:15170–7; PMID:25392485; http://dx.doi.org/10.1523/JNEUROSCI.3236-14.2014
   PubMed Web of Science ®Google Scholar
• Franco-Zorrilla JM, Valli A, Todesco M, Mateos I, Puga MI, Rubio-Somoza I, Leyva A, Weigel D, García JA, Paz-Ares J. Target mimicry provides a new mechanism for regulation of microRNA activity. Nat Geneat 2007; 39:1033–7; PMID:17643101; http://dx.doi.org/10.1038/ng2079
   PubMed Web of Science ®Google Scholar
• Ebert MS, Neilson JR, Sharp PA. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 2007; 4:721–6; PMID:17694064; http://dx.doi.org/10.1038/nmeth1079
   PubMed Web of Science ®Google Scholar
• Talhouarne GJ, Gall JG. Lariat intronic RNAs in the cytoplasm of Xenopus tropicalis oocytes. RNA 2014; 20:1476–87; PMID:25051970; http://dx.doi.org/10.1261/rna.045781.114
   PubMed Web of Science ®Google Scholar
• Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi B, Gonatopoulos-Pournatzis T, Frey B, Irimia M, Blencowe BJ. Wide spread intron retention in mammals functionally tunes transcriptomes. Genome Res 2014; 24:1774–86; PMID:25258385; http://dx.doi.org/10.1101/gr.177790.114
   PubMed Web of Science ®Google Scholar
• Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, et al. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 2012; 149:1393–406; PMID:22658674; http://dx.doi.org/10.1016/j.cell.2012.04.031
   PubMed Web of Science ®Google Scholar
• Hentze MW, Preiss T. Circular RNAs: splicing's enigma variations. EMBO J 2013; 32:923–5; PMID:23463100; http://dx.doi.org/10.1038/emboj.2013.53
   PubMed Web of Science ®Google Scholar
• Chen CY, Sarnow P. Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs. Science 1995; 268:415–7; PMID:7536344; http://dx.doi.org/10.1126/science.7536344
   PubMed Web of Science ®Google Scholar
• Lasda E, Parker R. Circular RNAs: diversity of form and function. RNA 2014; 20:1829–42; PMID:25404635; http://dx.doi.org/10.1261/rna.047126.114
   PubMed Web of Science ®Google Scholar
• Jeck WR, Sharpless NE. Detecting and characterizing circular RNAs. Nat Biotechnol 2014; 32:453–61; PMID:24811520; http://dx.doi.org/10.1038/nbt.2890
   PubMed Web of Science ®Google Scholar
• Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, Park IH, Kim KS, Daley GQ, Kornblum HI, et al. MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell 2010; 7:671–81; PMID:21112562; http://dx.doi.org/10.1016/j.stem.2010.11.012
   PubMed Web of Science ®Google Scholar
• Li P, Chen S, Chen H, Mo X, Li T, Shao Y, Xiao B, Guo J. Using circular RNA as a novel type of biomarker in the screening of gastric cancer. Clin Chim Acta 2015; 444:132–6; PMID:25689795; http://dx.doi.org/10.1016/j.cca.2015.02.018
   PubMed Web of Science ®Google Scholar
• Bachmayr-Heyda A, Reiner AT, Auer K, Sukhbaatar N, Aust S, Bachleitner-Hofmann T, Mesteri I, Grunt TW, Zeillinger R, Pils D. Correlation of circular RNA abundance with proliferation–exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues. SciRep 2015; 5:8057; PMID:25624062; http://dx.doi.org/10.1038/srep08057
   PubMed Web of Science ®Google Scholar
• Rokavec M, Li H, Jiang L, Hermeking H. The p53/microRNA connection in gastrointestinal cancer. Clin Exp Gastroenterol 2014; 7:395–413; PMID:25328413
   PubMedGoogle Scholar
• Hansen TB, Kjems J, Damgaard CK. Circular RNA and miR-7 in cancer. Cancer Res 2013; 73:5609–12; PMID:24014594; http://dx.doi.org/10.1158/0008-5472.CAN-13-1568
   PubMed Web of Science ®Google Scholar
• Wu HH, Lin WC, Tsai KW. Advances in molecular biomarkers for gastric cancer: miRNAs as emerging novel cancer markers. Expert Rev Mol Med 2014; 16, e1; PMID:24456939; http://dx.doi.org/10.1017/erm.2013.16
   PubMed Web of Science ®Google Scholar
• Chen YJ, Chien PH, Chen WS, Chien YF, Hsu YY, Wang LY, Chen JY, Lin CW, Huang TC, Yu YL, et al. Hepatitis B Virus-Encoded X Protein Downregulates EGFR Expression via Inducing MicroRNA-7 in Hepatocellular Carcinoma Cells. Evid Based Complement Alternat Med 2013; 2013:682380; PMID:23840262; http://dx.doi.org/10.1155/2013/682380
   PubMed Web of Science ®Google Scholar
• Zhou X, Hu Y, Dai L, Wang Y, Zhou J, Wang W, Di W, Qiu L. MicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer. PLoS ONE 2014; 9, e96718; PMID:24816687; http://dx.doi.org/10.1371/journal.pone.0096718
   PubMed Web of Science ®Google Scholar
• Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS, Leedman PJ. Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem 2009; 284:5731–41; PMID:19073608; http://dx.doi.org/10.1074/jbc.M804280200
   PubMed Web of Science ®Google Scholar
• Fang Y, Xue JL, Shen Q, Chen J, Tian L. MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma. Hepatology 2012; 55:1852–62; PMID:22234835; http://dx.doi.org/10.1002/hep.25576
   PubMed Web of Science ®Google Scholar
• Arteaga CL. The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia. J. Clin. Oncol 2001; 19:32S–40S; PMID:11560969
   PubMed Web of Science ®Google Scholar
• Janbabai G, Oladi Z, Farazmandfar T, Taghvaei T, Naghshvar F. The prognostic impact of EGFR, ErbB2 and MET gene amplification in human gastric carcinomas as measured by quantitative Real-Time PCR. J Cancer Res Clin Oncol 2015; 141:1945–52; PMID:25820598; http://dx.doi.org/10.1007/s00432-015-1965-7
   PubMed Web of Science ®Google Scholar
• Zhao X, Dou W, He L, Liang S, Tie J, Liu C, Li T, Lu Y, Mo P, Shi Y, et al. MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. Oncogene 2013; 32:1363–72; PMID:22614005; http://dx.doi.org/10.1038/onc.2012.156
   PubMed Web of Science ®Google Scholar
• Zhang X, Hu S, Zhang X, Wang L, Zhang X, Yan B, Zhao J, Yang A, Zhang R. MicroRNA-7 arrests cell cycle in G1 phase by directly targeting CCNE1 in human hepatocellular carcinoma cells. Biochem Biophys Res Commun 2014; 443:1078–84; PMID:24370822; http://dx.doi.org/10.1016/j.bbrc.2013.12.095
   PubMed Web of Science ®Google Scholar
• Ma C, Qi Y, Shao L, Liu M, Li X, Tang H. Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cells. IUBMB Life 2013; 65:1026–34; PMID:24339204; http://dx.doi.org/10.1002/iub.1231
   PubMed Web of Science ®Google Scholar
• Chinnappan D, Xiao D, Ratnasari A, Andry C, King TC, Weber HC. Transcription factor YY1 expression in human gastrointestinal cancer cells. Int J Oncol 2009; 34:1417–23; PMID:19360355
   PubMed Web of Science ®Google Scholar
• Zhang N, Li X, Wu CW, Dong Y, Cai M, Mok MT, Wang H, Chen J, Ng SS, Chen M, Sung JJ, et al. microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis. Oncogene 2013; 32:5078–88; PMID:23208495; http://dx.doi.org/10.1038/onc.2012.526
   PubMed Web of Science ®Google Scholar
• Suto T, Yokobori T, Yajima R, Morita H, Fujii T, Yamaguchi S, Altan B, Tsutsumi S, Asao T, Kuwano H. MicroRNA-7 expression in colorectal cancer is associated with poor prognosis and regulates cetuximab sensitivity via EGFR regulation. Carcinogenesis 2015; 36:338–45; PMID:25503932; http://dx.doi.org/10.1093/carcin/bgu242
   PubMed Web of Science ®Google Scholar
• Huynh FC, Jones FE. MicroRNA-7 inhibits multiple oncogenic pathways to suppress HER2Delta16 mediated breast tumorigenesis and reverse trastuzumab resistance. PLoS One 2014; 9, e114419; PMID:25532106; http://dx.doi.org/10.1371/journal.pone.0114419
   PubMed Web of Science ®Google Scholar
• Babae N, Bourajjaj M, Liu Y, Van Beijnum JR, Cerisoli F, Scaria PV, Verheul M, Van Berkel MP, Pieters EH, Van Haastert RJ, et al. Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma. Oncotarget 2014; 5:6687–700; PMID:25149532; http://dx.doi.org/10.18632/oncotarget.2235
   PubMed Web of Science ®Google Scholar
• Liu Z, Jiang Z, Huang J, Huang S, Li Y, Yu S, Yu S, Liu X. miR-7 inhibits glioblastoma growth by simultaneously interfering with the PI3K/ATK and Raf/MEK/ERK pathways. Int J Oncol 2014; 44:1571–80; PMID:24603851; http://dx.doi.org/10.3892/ijo.2014.2322.
   PubMed Web of Science ®Google Scholar
• Liu R, Liu X, Zheng Y, Gu J, Xiong S, Jiang P, Jiang X, Huang E, Yang Y, Ge D. MicroRNA-7 sensitizes non-small cell lung cancer cells to paclitaxel. Oncol Lett 2014; 8:2193–2200; PMID:25289099
   PubMed Web of Science ®Google Scholar
• Ma J, Fang B, Zeng F, Pang H, Zhang J, Shi Y, Wu X, Cheng L, Ma C, Xia J, et al. Curcumin inhibits cell growth and invasion through up-regulation of miR-7 in pancreatic cancer cells. Toxicol Lett 2014; 231:82–91; PMID:25256401; http://dx.doi.org/10.1016/j.toxlet.2014.09.014
   PubMed Web of Science ®Google Scholar
• Hao Z, Yang J, Wang C, Li Y, Zhang Y, Dong X, Zhou L, Liu J, Zhang Y, Qian J. MicroRNA-7 inhibits metastasis and invasion through targeting focal adhesion kinase in cervical cancer. Int J Clin Exp Med 2015; 8:480–7; PMID:25785020
   PubMed Web of Science ®Google Scholar
• Bak RO, Mikkelsen JG. miRNA sponges: soaking up miRNAs for regulation of gene expression. Wiley Interdiscip Rev RNA 2014; 5:317–33; PMID:24375960; http://dx.doi.org/10.1002/wrna.1213
   PubMed Web of Science ®Google Scholar
• Salzman J, Chen RE, Olsen MN, Wang PL, Brown PO. Cell-type specific features of circular RNA expression. PLoS Genet 2013; 9, e1003777; PMID:24039610; http://dx.doi.org/10.1371/annotation/f782282b-eefa-4c8d-985c-b1484e845855
   PubMed Web of Science ®Google Scholar
• Granados-Riveron JT, Aquino-Jarquin G. Does the linear Sry transcript function as a ceRNA for miR-138? The sense of antisense. F1000Res 2014; 3:90; PMID:25580223; http://dx.doi.org/10.12688/f1000research.3872.2
   PubMedGoogle Scholar
• Guo JU, Agarwal V, Guo H, Bartel DP. Expanded identification and characterization of mammalian circular RNAs. Genome Biol 2014; 15:409; PMID:25070500; http://dx.doi.org/10.1186/s13059-014-0409-z
   PubMed Web of Science ®Google Scholar
• Wang Q, Tang H, Yin S, Dong C. Downregulation of microRNA-138 enhances the proliferation, migration and invasion of cholangiocarcinoma cells through the upregulation of RhoC/p-ERK/MMP-2/MMP-9. Oncol Rep 2013; 29:2046–52; PMID:23446431; http://dx.doi.org/10.3892/or.2013.2304
   PubMed Web of Science ®Google Scholar
• Long L, Huang G, Zhu H, Guo Y, Liu Y, Huo J. Down-regulation of miR-138 promotes colorectal cancer metastasis via directly targeting TWIST2. J Transl Med 2013; 11:275; PMID:24171926; http://dx.doi.org/10.1186/1479-5876-11-275
   PubMed Web of Science ®Google Scholar
• Ayaz L, Çayan F, Balci Ş, Görür A, Akbayir S, Yıldırım Yaroğlu H, Doğruer Unal N, Tamer L. Circulating microRNA expression profiles in ovarian cancer. J Obstet Gynaecol 2014; 34:620–4; PMID:24911418; http://dx.doi.org/10.3109/01443615.2014.919998
   PubMedGoogle Scholar
• Chen P, Zeng M, Zhao Y, Fang X. Upregulation of Limk1 caused by microRNA-138 loss aggravates the metastasis of ovarian cancer by activation of Limk1/cofilin signaling. Oncol Rep 2014; 32:2070–6; PMID:25190487; http://dx.doi.org/10.3892/or.2014.3461
   PubMed Web of Science ®Google Scholar
• Yeh YM, Chuang CM, Chao KC, Wang LH. MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1alpha. Int J Cancer 2013; 133:867–78; PMID:23389731; http://dx.doi.org/10.1002/ijc.28086
   PubMed Web of Science ®Google Scholar
• Yang H, Tang Y, Guo W, Du Y, Wang Y, Li P, Zang W, Yin X, Wang H, Chu H, et al. Up-regulation of microRNA-138 induce radiosensitization in lung cancer cells. Tumour Biol 2014; 35:6557–65; PMID:24691972; http://dx.doi.org/10.1007/s13277-014-1879-z
   PubMed Web of Science ®Google Scholar
• Yang H, Luo J, Liu Z, Zhou R, Luo H. MicroRNA-138 Regulates DNA Damage Response in Small Cell Lung Cancer Cells by Directly Targeting H2AX. Cancer Invest 2015; 33:126–36; PMID:25699650; http://dx.doi.org/10.3109/07357907.2015
   PubMed Web of Science ®Google Scholar
• Berg V, Rusch M, Vartak N, Jüngst C, Schauss A, Waldmann H, Hedberg C, Pallasch CP, Bastiaens PI, Hallek M, et al. miRs-138 and −424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in chronic lymphocytic leukemia. Blood 2015; 125(19), 2948–2957; PMID:25670628; http://dx.doi.org/10.1182/blood-2014-07-586511
   PubMed Web of Science ®Google Scholar
• Kosik KS. Molecular biology: Circles reshape the RNA world. Nature 2013; 495:322–4; PMID:23446351; http://dx.doi.org/10.1038/nature11956
   PubMed Web of Science ®Google Scholar
• Lee KM, Choi EJ, Kim IA. microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling. Radiother Oncol 2011; 101:171–6; PMID:21676478; http://dx.doi.org/10.1016/j.radonc.2011.05.050
   PubMed Web of Science ®Google Scholar
• Bockhorn J, Prat A, Chang Y F, Liu X, Huang S, Shang M, Nwachukwu C, Gomez-Vega MJ, Harrell JC, Olopade OI, et al. Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models. Cancer Res 2014; 74(24), 7406–7417; PMID:25339353; http://dx.doi.org/10.1158/0008-5472.CAN-14-1188
   PubMed Web of Science ®Google Scholar
• Tay FC, Lim JK, Zhu H, Hin LC, Wang S. Using artificial microRNA sponges to achieve microRNA loss-of-function in cancer cells. Adv Drug Deliv Rev 2014; PMID:24859534; http://dx.doi.org/10.1016/j.addr.2014.05.010
   PubMed Web of Science ®Google Scholar
• Santoro MM. Antiangiogenic cancer drug using the zebrafish model. Arterioscler Thromb Vasc Biol 2014; 34:1846–53; PMID:24903092; http://dx.doi.org/10.1161/ATVBAHA.114.303221
   PubMed Web of Science ®Google Scholar
• Mohseny AB, Hogendoorn PC. Zebrafish as a model for human osteosarcoma. Adv Exp Med Biol 2014; 804:221–36; PMID:24924177; http://dx.doi.org/10.1007/978-3-319-04843-7_12
   PubMed Web of Science ®Google Scholar
• Chao CW, Chan DC, Kuo A, Leder P. The mouse formin (Fmn) gene: abundant circular RNA transcripts and gene-targeted deletion analysis. Mol. Med 1998; 4:614–28; PMID:9848078
   PubMed Web of Science ®Google Scholar