1,216
Views
6
CrossRef citations to date
0
Altmetric
Research Paper

Competitive learning suggests circulating miRNA profiles for cancers decades prior to diagnosis

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 1416-1426 | Received 26 Mar 2020, Accepted 14 May 2020, Published online: 16 Jun 2020

References

  • He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5(7):522–531.
  • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–297.
  • Hart M, Kern F, Backes C, et al. The deterministic role of 5-mers in microRNA-gene targeting. RNA Biol. 2018;15(6):819–825.
  • Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature. 2005;435(7043):834–838.
  • Maciotta S, Meregalli M, Torrente Y. The involvement of microRNAs in neurodegenerative diseases. Front Cell Neurosci. 2013;7:265.
  • Backes C, Meese E, Keller A. Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects. Mol Diagn Ther. 2016;20(6):509–518.
  • Fehlmann T, Ludwig N, Backes C, et al. Distribution of microRNA biomarker candidates in solid tissues and body fluids. RNA Biol. 2016;13(11):1084–1088.
  • Hjerkind KV, Gislefoss RE, Tretli S, et al. cohort profile update: the janus serum bank cohort in Norway. Int J Epidemiol. 2017;46(4):1101–2f.
  • Jellum E, Andersen A, Lund-Larsen P, et al. The JANUS serum bank. Sci Total Environ. 1993;139-140:527–535.
  • Gislefoss RE, Grimsrud TK, Morkrid L. Long-term stability of serum components in the Janus Serum Bank. Scand J Clin Lab Invest. 2008;68(5):402–409.
  • Langseth H, Gislefoss RE, Martinsen JI, et al. Cohort profile: the janus serum bank cohort in Norway. Int J Epidemiol. 2017;46(2):403–4g.
  • Fehlmann T, Backes C, Alles J, et al. A high-resolution map of the human small non-coding transcriptome. Bioinformatics. 2018;34(10):1621–1628.
  • Keller A, Leidinger P, Vogel B, et al. miRNAs can be generally associated with human pathologies as exemplified for miR-144. BMC Med. 2014;12(1):224.
  • Keller A, Leidinger P, Bauer A, et al. Toward the blood-borne miRNome of human diseases. Nat Methods. 2011;8(10):841–843.
  • Alles J, Fehlmann T, Fischer U, et al. An estimate of the total number of true human miRNAs. Nucleic Acids Res. 2019;47(7):3353–3364.
  • Keller A, Meese E. Can circulating miRNAs live up to the promise of being minimal invasive biomarkers in clinical settings? Wiley Interdiscip Rev RNA. 2016;7(2):148–156.
  • Keller A, Rounge T, Backes C, et al. Sources to variability in circulating human miRNA signatures. RNA Biol. 2017;14(12):1791–1798.
  • Rounge TB, Umu SU, Keller A, et al. Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity. Sci Rep. 2018;8(1):17650.
  • Keller A, Leidinger P, Gislefoss R, et al. Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis. RNA Biol. 2011;8(3):506–516.
  • Umu SU, Langseth H, Keller A, et al. A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis. Mol Oncol. 2020;14(2):235–247.
  • Baglietto L, Ponzi E, Haycock P, et al. DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk. Int J Cancer. 2017;140:50–61.
  • Fasanelli F, Baglietto L, Ponzi E, et al. Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts. Nat Commun. 2015;6(1):10192.
  • Meng S, De Vivo I, Liang L, et al. Pre-diagnostic leukocyte mitochondrial DNA copy number and risk of lung cancer. Oncotarget. 2016;7(19):27307–27312.
  • Dai L, Tsay JC, Li J, et al. Autoantibodies against tumor-associated antigens in the early detection of lung cancer. Lung Cancer. 2016;99:172–179.
  • Zhou B, Shu B, Yang J, et al. C-reactive protein, interleukin-6 and the risk of colorectal cancer: a meta-analysis. Cancer Causes Control. 2014;25(10):1397–1405.
  • Touvier M, Fezeu L, Ahluwalia N, et al. Pre-diagnostic levels of adiponectin and soluble vascular cell adhesion molecule-1 are associated with colorectal cancer risk. World J Gastroenterol. 2012;18(22):2805–2812.
  • Opstal-van Winden AW, Krop EJ, Karedal MH, et al. Searching for early breast cancer biomarkers by serum protein profiling of pre-diagnostic serum; a nested case-control study. BMC Cancer. 2011;11(1):381.
  • Trabert B, Pinto L, Hartge P, et al. Pre-diagnostic serum levels of inflammation markers and risk of ovarian cancer in the prostate, lung, colorectal and ovarian cancer (PLCO) screening trial. Gynecol Oncol. 2014;135(2):297–304.
  • Kohonen T. Self-organized formation of topologically correct feature maps. Biol Cybern. 1982;43(1):59–69.
  • Meder B, Backes C, Haas J, et al. Influence of the confounding factors age and sex on microRNA profiles from peripheral blood. Clin Chem. 2014;60(9):1200–1208.
  • Ludwig N, Hecksteden A, Kahraman M, et al. Spring is in the air: seasonal profiles indicate vernal change of miRNA activity. RNA Biol. 2019;16(8):1034–1043.
  • ElSharawy A, Keller A, Flachsbart F, et al. Genome-wide miRNA signatures of human longevity. Aging Cell. 2012;11(4):607–616.
  • Nagy ZB, Barták BK, Kalmár A, et al. Comparison of circulating miRNAs expression alterations in matched tissue and plasma samples during colorectal cancer progression. Pathol Oncol Res. 2019;25(1):97–105.
  • Usuba W, Urabe F, Yamamoto Y, et al. Circulating miRNA panels for specific and early detection in bladder cancer. Cancer Sci. 2019;110(1):408–419.
  • Zhang Y, Kang R, Liu W, et al. Identification and analysis of P53-mediated competing endogenous RNA network in human hepatocellular carcinoma. Int J Biol Sci. 2017;13(9):1213–1221.
  • Zaporozhchenko IA, Ponomaryova AA, Rykova EY, et al. The potential of circulating cell-free RNA as a cancer biomarker: challenges and opportunities. Expert Rev Mol Diagn. 2018;18(2):133–145.
  • Fitzgerald RC. Big data is crucial to the early detection of cancer. Nat Med. 2020;26(1):19–20.
  • Fehlmann T, Kahraman M, Ludwig N, et al. Evaluating the use of circulating MicroRNA profiles for lung cancer detection in symptomatic patients. JAMA Oncol. 2020;6(5):714.
  • Blondal T, Jensby Nielsen S, Baker A, et al. Assessing sample and miRNA profile quality in serum and plasma or other biofluids. Methods. 2013;59(1):S1–6.
  • Backes C, Khaleeq QT, Meese E, et al. miEAA: microRNA enrichment analysis and annotation. Nucleic Acids Res. 2016;44(W1):W110–6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.