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Research Article

2,3,7,8 Tetrachlorodibenzo-p-Dioxin (TCDD) Directly Enhances the Maturation and Apoptosis of Dendritic Cells In Vitro

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Pages 159-166 | Received 17 Jul 2004, Accepted 02 Dec 2004, Published online: 09 Oct 2008

REFERENCES

  • Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y. J., Pulendran B., Palucka K. Immunobiology of dendritic cells. Annual Review of Immunology 2000; 18: 767–811
  • Clark D. A., Sweeney G., Safe S., Hancock E., Kilburn D. G., Gauldie J. Cellular and genetic basis for suppression of cytotoxic T-cell generation by haloaromatic hydrocarbons. Immunopharmacology 1983; 6: 143–153
  • Cyster J. G. Chemokines and the homing of dendritic cells to the T-cell areas of lymphoid organs. Journal of Experimental Medicine 1999; 189: 447–450
  • De Smedt T., Pajak B., Klaus G. G. B., Noelle R. J., Urbain J., Leo O., Moser M. Antigen-specific T lymphocytes regulate lipopolysaccharide-induced apoptosis of dendritic cells in vivo. Journal of Immunology 1998; 161: 4476–4479
  • Funatake C. J., Dearstyne E. A., Steppan L. B., Shepherd D. M., Spanjaard E. S., Marchak-Rothstein A., Kerkvliet N. I. Early consequences of 2,3,7,8-Tetrachlorodibenzo-p-dioxin exposure on the activation and survival of antigen-specific T-cells. Toxicol. Sci. 2004; 82: 129–142
  • Gardner A. M., Xu F. H., Fady C., Jacoby F. J., Duffey D. C., Tu Y., Lichtenstein A. Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide. Free Radical Biology and Medicine 1997; 22: 73–83
  • Gett A. V., Sallusto F., Lanzavecchia A., Geginat J. T-Cell Fitness Determined by Signal Strength. Nature Immunology 2003; 4: 355–360
  • Inaba K., Inaba M., Romani N., Aya H., Deguchi M., Ikehara S., Muramatsu S., Steinman R. M. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. Journal of Experimental Medicine 1992; 176: 1693–1702
  • Josien B. R., Li H. L., Ingulli E., Sarma S., Wong R., Vologodskaia M., Steinman R. M., Choi Y. TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells In vivo. Journal of Experimental Medicine 2000; 191: 495–502
  • Kerkvliet N. I., Baecher-Steppan L., Shepherd D. M., Oughton J. A., Vorderstrasse B. A., Dekrey G. K. Inhibition of TC-1 cytokine production, effector cytotoxic T lymphocyte development and alloantibody production by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Journal of Immunology 1996; 157: 2310–2319
  • Kerkvliet N. I., Steppan L. B., Brauner J. A., Deyo J. A., Henderson M. C., Tomar R. S., Buhler D. R. Influence of the Ah locus on the humoral immunotoxicity of 2,3,7, 8-tetrachlorodibenzo-p-dioxin: Evidence for Ah-receptor-dependent and Ah-receptor-independent mechanisms of immunosuppression. Toxicology and Applied Pharmacology 1990; 105: 26–36
  • Kern P. A., Dicker-Brown A., Said S. T., Kennedy R., Fonseca V. A. The stimulation of tumor necrosis factor and inhibition of glucose transport and lipoprotein lipase in adipose cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Metabolism 2002; 51: 65–68
  • Laiosa M. D., Wyman A., Murante F. G., Fiore N. C., Staples J. E., Gasiewicz T. A., Silverstone A. E. Cell proliferation arrest within intrathymic lymphocyte progenitor cells causes thymic atrophy mediated by the aryl hydrocarbon receptor. Journal of Immunology 2003; 171: 4582–4591
  • Laupeze B., Amiot L., Sparfel L., Le Ferrec E., Fauchet R., Fardel O. Polycyclic aromatic hydrocarbons affect functional differentiation and maturation of human monocyte-derived dendritic cells. Journal of Immunology, 168: 2652–2658
  • Matsue H., Matsue K., Walters M., Okumura K., Yagita H., Takashima A. Induction of antigen-specific immunosuppression by CD95L cDNA-transfected ‘killer’ dendritic cells. Nature Med. 1999; 5: 930–937
  • Matyszak M. K., Citterio S., Rescigno M., Ricciardi-Castagnoli P. Differential effects of corticosteroids during different stages of dendritic cell maturation. European Journal of Immunology 2000; 30: 1233–1242
  • Miga A. J., Masters S. R., Durell B. G., Gonzalez M., Jenkins M. K., Maliszewski C. R., Kikutani H., Wade W. F., Noelle R. J. Dendritic cell longevity and T-cell persistence is controlled by CD154-CD40 interactions. European Journal of Immunology 2001; 31: 959–965
  • Moos A. B., Oughton J. A., Kerkvliet N. I. The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on tumor necrosis factor (TNF) production by peritoneal cells. Toxicology Letters 1997; 90: 145–153
  • Nagata S. Fas ligand-induced apoptosis. Annual Review of Genetics 1999; 33: 29–55
  • Nagata S., Golstein P. The Fas death factor. Science 1995; 267: 1449–1456
  • Nicholson D. W., Thornberry N. A. Caspases: Killer proteases. Trends in Biolchemical Science 1997; 22: 299–306
  • Ogasawara J., Suda T., Nagata S. Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody. Journal of Experimental Medicine 1995; 181: 485–491
  • Oyama T., Ran S, Ishida T., Nadaf S., Kerr L., Carbone D. P., Gabrilovich D I. Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells. Journal of Immunology 1998; 160: 1224–1232
  • Piemonti L., Monti P., Allavena P., Sironi M., Soldini L., Leone B. E., Socci C., Di C. V. Glucocorticoids affect human dendritic cell differentiation and maturation. Journal of Immunology 1999; 162: 6473–6481
  • Rescigno M., Martino M., Sutherland C. L., Gold M. R., Ricciardi-Castagnoli P. Dendritic cell survival and maturation are regulated by different signalling pathways. Journal of Experimental Medicine 1998; 188: 2175–2180
  • Rier S. E., Coe C. L., Lemieux A. M., Martin D. C., Morris R., Lucier G. W., Clark G. C. Increased tumor necrosis factor-α production in peripheral blood leukocytes from TCDD-exposed rhesus monkeys. Toxicolgical Sciences 2001; 60: 327–337
  • Ruby C. E., Leid M., Kerkvliet N. I. 2,3,7,8-tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-α and anti-CD40-induced activation of NF-κ B/Rel in dendritic cells: p50 homodimer activation is not affected. Molecular Pharmacology 2002; 62: 722–728
  • Sallusto F., Lanzavecchia A. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunological Reviews 2000; 177: 134–140
  • Shepherd D. M., Dearstyne E. A., Kerkvliet N. I. The effects of TCDD on the activation of ovalbumin (OVA)-specific DO11.10 transgenic CD4(+) T-cells in adoptively transferred mice. Toxicol. Sci. 2000; 56: 340–350
  • Shepherd D. M., Steppan L. B., Hedstrom O. L., Kerkvliet N. I. Anti-CD40 treatment of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-exposed C57Bl/6 mice induces activation of antigen presenting cells yet fails to overcome TCDD-induced suppression of allograft immunity. Toxicol. Appl. Pharmacol. 2001; 170: 10–22
  • Shin K. J., Bae S. S., Hwang Y. A., Seo J. K., Ryu S. H., Suh P. G. 2,2′,4,6,6′-Pentachlorobiphenyl induces apoptosis in human monocytic cells. Toxicology and Applied Pharmacology 2000; 169: 1–7
  • Tibbetts M. D., Zheng L., Lenardo M. J. The death effector domain protein family: Regulators of cellular homeostasis. Nature Immunology 2003; 4: 404–409
  • van Stipdonk M. J. B., Hardenberg G., Bijker M. S., Lemmens E. E., Droin N. M., Green D. R., Schoenberger S. P. Dynamic programming of CD8+ T lymphocyte responses. Nature Immunology 2003; 4: 361–365
  • Verhasselt V., Vanden Berghe W., Vanderheyde N., Willems F., Haegeman G., Goldman M. N-acetyl-L-cysteine inhibits primary human T-cell responses at the dendritic cell level: Association with NF-kappaB inhibition. Journal of Immunology 1999; 162: 2569–2574
  • Vorderstrasse B. A., Dearstyne E. D., Kerkvliet N. I. Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the antigen-presenting activity of dendritic cells. Toxicology 2003; 72: 15–28
  • Vorderstrasse B. A., Kerkvliet N. I. 2,3,7,8-tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules. Toxicol. Appl. Pharmacol. 2001; 171: 117–125
  • Wang C. Y., Mayo M. W., Korneluk R. G., Goeddel D. V., Baldwin A. S., Jr. NF-κ B antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998; 281: 1680–1683
  • Winzler C., Rovere P., Rescigno M., Granucci F., Penna G., Adorini L., Zimmerman V. S., Davoust J., Ricciardi-Castagnoli P. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. Journal of Experimental Medicine 1997; 185: 317–328
  • Zhang J., Cado D., Chen A., Kabra M. H., Winoto A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 1998; 392: 296–300
  • Zhang Y., Mukaida N., Wang J., Harada A., Akiyama M., Matsushima K. Induction of dendritic cell differentiation by granulocyte-macrophage colony-stimulating factor, stem cell factor, and tumor necrosis factor alpha in vitro from lineage phenotypes-negative c-kit+ murine hematopoietic progenitor cells. Blood 1997; 90: 4842–4853

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