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Research Article

Immunotoxic effects of gold and silver nanoparticles: Inhibition of mitogen-induced proliferative responses and viability of human and murine lymphocytes in vitro

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Pages 897-902 | Received 24 Jan 2016, Accepted 06 Sep 2016, Published online: 18 Oct 2016

References

  • Almeida J, Figueroa E, Drezek R. 2014. Gold nanoparticle-mediated cancer immunotherapy. Nanomedicine. 10:503–514.
  • Basu S, Ghosh S, Kundu S, Panigrahi S, Praharaj S, Pande S, Jana S, Pal T. 2007. Biomolecule induced nanoparticle aggregation: Effect of particle size on inter-particle coupling. J Colloid Interface Sci. 313:724–734.
  • Becker K, Schroecksnadel S, Geisler S, Carriere M, Gostner J, Schennach H, Herlin N, Fuchs D. 2014. TiO2 nanoparticles and bulk material stimulate human peripheral blood mononuclear cells. Food Chem Toxicol. 65:63–69.
  • Bhattacharya R, Patra C, Verma R, Kumar S, Greipp P, Mukherjee P. 2007. Gold nanoparticles inhibit the proliferation of multiple myeloma cells. Adv Mater. 19:711–716.
  • Boyum A. 1964. Separation of white blood cells. Nature. 204:793–794.
  • Butler K, Peeler D, Casey B, Dair B, Elespuru R. 2015. Silver nanoparticles: Correlating nanoparticle size and cellular uptake with genotoxicity. Mutagenesis. 30:577–591.
  • Corot C, Robert P, Idee J, Port M. 2006. Recent advances in iron oxide nanocrystal technology for medical imaging. Adv Drug Deliv Rev. 58:1471–1504.
  • Dobrovolskaia M, Aggarwal P, Hall J, McNeil SE. 2008. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm. 5:487–495.
  • Dobrovolskaia M, McNeil S. 2007. Immunological properties of engineered nanomaterials. Nat Nanotechnol. 2:469–478.
  • Elsabahy M, Wooley K. 2013. Cytokines as biomarkers of nanoparticle immunotoxicity. Chem Soc Rev. 21:5552–5576.
  • Ghosh M, Manivannan J, Sinha S, Chakraborty A, Mallick S, Bandyopadhyay M, Mukherjee A. 2012. In vitro and in vivo genotoxicity of silver nanoparticles. Mutat Res. 749:60–69.
  • Greulich C, Diendorf J, Gessmann J, Simon T, Habijan T, Eggeler G, Schildhauer T, Epple M, Köller M. 2011. Cell type-specific responses of peripheral blood mononuclear cells to silver nanoparticles. Acta Biomater. 7:3505–3514.
  • Guevel X, Palomares F, Torresb M, Blancab M, Fernandez T, Mayorgab C. 2015. Nanoparticle size influences proliferative responses of lymphocyte sub-populations. RSC Adv. 5:85305–85309.
  • Hanini A, Schmitt A, Kacem K, Chau F, Ammar S, Gavard J. 2011. Evaluation of iron oxide nanoparticle biocompatibility. Int J Nanomed. 6:787–794.
  • Huang H, Lai W, Cui M, Liang L, Lin Y, Fang Q, Liu Y, Xie L. 2016. An evaluation of blood compatibility of silver nanoparticles. Sci Rep. 6:25518. doi: 10.1038/srep25518.
  • Hussain S, Vanoirbeek J, Hoet P. 2012. Interactions of nanomaterials with the immune system. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 4:169–183.
  • Jiao Q, Li L, Mu Q, Zhang Q. 2014. Immunomodulation of nanoparticles in nanomedicine applications. Biomed Res Intl. 2014:426028.
  • Kasyapa C, Ramanadham M. 1992. Alkaline phosphatase activity is expressed only in B-lymphocytes committed to proliferation. Immunol Lett. 31:111–116.
  • Lara H, Garza-Treviño E, Ixtepan-Turrent L, Singh D. 2011. Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds. J Nanobiotechnology. 9:30. doi: 10.1186/1477-3155-9-30.
  • Lee P, Meisel D. 1982. Adsorption and surface-enhanced Raman dyes on silver and gold sols. J Phys Chem. 86:3391–3395.
  • Liptrott N, Kendall E, Nieves D, Farrell J, Rannard S, Fernig D, Owen A. 2014. Partial mitigation of gold nanoparticle interactions with human lymphocytes by surface functionalization with a 'mixed matrix'. Nanomedicine. 9:2467–2479.
  • Liu Y, Chen Z, Wang J. 2011. Systematic evaluation of biocompatibility of magnetic Fe3O4 nanoparticles with six different mammalian cell lines. J Nanopart Res. 13:199–212.
  • Liu X, Huang N, Li H, Jin Q, Ji J. 2013. Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells. Langmuir. 29:9138–9148.
  • Loza K, Diendorf J, Sengstock C, Ruiz-Gonzalez L, Gonzalez-Calbet J, Vallet-Regi M, Koller M, Epple M. 2014. Dissolution and biological effects of silver nanoparticles in biological media. J Mater Chem. 2:1634–1643.
  • Małaczewska J. 2015. The splenocyte proliferative response and cytokine secretion in mice after oral administration of commercial gold nano-colloid. Pol J Vet Sci. 18:181–189.
  • Mironava T, Hadjiargyrou M, Simon M, Jurukovski V, Rafailovich M. 2010. Gold nanoparticles cellular toxicity and recovery: Effect of size, concentration and exposure time. Nanotoxicology. 4:120–137.
  • Mukherjee P, Bhattacharya R, Bone N, Lee Y, Patra C, Wang S, Lu L, Secreto C, Banerjee P, Yaszemski M, et al. 2007. Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): Enhancing apoptosis. J Nanobiotechnol. 5:4. doi: 10.1186/1477-3155-5-4.
  • Nune S, Gunda P, Thallapally P, Lin Y, Forrest M, Berkland C. 2009. Nanoparticles for biomedical imaging. Expert Opin Drug Deliv. 6:1175–1194.
  • Rai M, Yadav A, Aniket G. 2009. Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv. 27:76–83.
  • Sabella S, Carney R, Brunetti V, Malvindi M, Al-Juffali N, Vecchio G, Janes S, Bakr O, Cingolani R, Stellacci F, et al. 2014. A general mechanism for intracellular toxicity of metal-containing nanoparticles. Nanoscale. 6:7052–7061.
  • Tomic S, Dokic J, Vasilijic S, Ogrinc N, Rudolf R, Pelicon P, Vucevic D, Milosavljevic P, Jankovic S, Anzel I, et al. 2014. Size-dependent effects of gold nanoparticles uptake on maturation and anti-tumor functions of human dendritic cells in vitro. PLoS One. 9:e96584. doi: 10.1371/journal.pone.0096584.
  • van der Zande M, Vandebriel R, van Doren E, Kramer E, Rivera Z, Serrano-Rojero C, Gremmer E, Mast J, Peters R, Hollman P, et al. 2012. Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure. ACS Nano. 6:7427–7442.
  • Vance M, Kuiken T, Vejerano E, McGinnis S, Hochella M, Rejeski D, Hull M. 2015. Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory. Beilstein J Nanotechnol. 6:1769–1780.
  • Vergallo C, Panzarini E, Izzo D, Carata E, Mariano S, Buccolieri A, Serra A, Manno D, Dini L. 2014. Cytotoxicity of β-D-glucose coated silver nanoparticles on human lymphocytes. AIP Conf Proc. 1603:78–86.
  • Villiers C, Freitas H, Couderc R, Villiers M, Marche P. 2010. Analysis of the toxicity of gold nanoparticles on the immune system: Effect on dendritic cell functions. J Nanopart Res. 12:55–60.
  • Zimmerman D, Gregory S, Kern M. 1977. Differentiation of lymphoid cells: The preferential binding of the lipid A moiety of lipopolysaccharide to B-lymphocyte populations. J Immunol. 119:1018–1023.
  • Zhao Y, Wang B, Feng W, Bai C. 2014. Nanotoxicology: Toxicological and biological properties of nanomaterials. Encyclopedia of Life Support Systems; [cited 2016 Aug 10]. Available from: http://www.eolss.net.
  • Zhornik E, Baranova L, Drozd E, Sudas M, Chau N, Buu N, Dung T, Chizhik S, Volotovski I. 2014. Silver nanoparticles induce lipid peroxidation and morphological changes in human lymphocytes surface. Biophysics. 59:380–386.
  • Zolnik B, Gonzalez-Fernandez A, Sadrieh N, Dobrovolskaia M. 2010. Nanoparticles and the immune system. Endocrinology. 151:458–465.

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