Immunotoxic effects of gold and silver nanoparticles: Inhibition of mitogen-induced proliferative responses and viability of human and murine lymphocytes in vitro

References

• Almeida J, Figueroa E, Drezek R. 2014. Gold nanoparticle-mediated cancer immunotherapy. Nanomedicine. 10:503–514.
   PubMed Web of Science ®Google Scholar
• Basu S, Ghosh S, Kundu S, Panigrahi S, Praharaj S, Pande S, Jana S, Pal T. 2007. Biomolecule induced nanoparticle aggregation: Effect of particle size on inter-particle coupling. J Colloid Interface Sci. 313:724–734.
   PubMed Web of Science ®Google Scholar
• Becker K, Schroecksnadel S, Geisler S, Carriere M, Gostner J, Schennach H, Herlin N, Fuchs D. 2014. TiO2 nanoparticles and bulk material stimulate human peripheral blood mononuclear cells. Food Chem Toxicol. 65:63–69.
   PubMed Web of Science ®Google Scholar
• Bhattacharya R, Patra C, Verma R, Kumar S, Greipp P, Mukherjee P. 2007. Gold nanoparticles inhibit the proliferation of multiple myeloma cells. Adv Mater. 19:711–716.
   Web of Science ®Google Scholar
• Boyum A. 1964. Separation of white blood cells. Nature. 204:793–794.
   PubMed Web of Science ®Google Scholar
• Butler K, Peeler D, Casey B, Dair B, Elespuru R. 2015. Silver nanoparticles: Correlating nanoparticle size and cellular uptake with genotoxicity. Mutagenesis. 30:577–591.
   PubMed Web of Science ®Google Scholar
• Corot C, Robert P, Idee J, Port M. 2006. Recent advances in iron oxide nanocrystal technology for medical imaging. Adv Drug Deliv Rev. 58:1471–1504.
   PubMed Web of Science ®Google Scholar
• Dobrovolskaia M, Aggarwal P, Hall J, McNeil SE. 2008. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm. 5:487–495.
   PubMed Web of Science ®Google Scholar
• Dobrovolskaia M, McNeil S. 2007. Immunological properties of engineered nanomaterials. Nat Nanotechnol. 2:469–478.
   PubMed Web of Science ®Google Scholar
• Elsabahy M, Wooley K. 2013. Cytokines as biomarkers of nanoparticle immunotoxicity. Chem Soc Rev. 21:5552–5576.
   Web of Science ®Google Scholar
• Ghosh M, Manivannan J, Sinha S, Chakraborty A, Mallick S, Bandyopadhyay M, Mukherjee A. 2012. In vitro and in vivo genotoxicity of silver nanoparticles. Mutat Res. 749:60–69.
   PubMed Web of Science ®Google Scholar
• Greulich C, Diendorf J, Gessmann J, Simon T, Habijan T, Eggeler G, Schildhauer T, Epple M, Köller M. 2011. Cell type-specific responses of peripheral blood mononuclear cells to silver nanoparticles. Acta Biomater. 7:3505–3514.
   PubMed Web of Science ®Google Scholar
• Guevel X, Palomares F, Torresb M, Blancab M, Fernandez T, Mayorgab C. 2015. Nanoparticle size influences proliferative responses of lymphocyte sub-populations. RSC Adv. 5:85305–85309.
   Web of Science ®Google Scholar
• Hanini A, Schmitt A, Kacem K, Chau F, Ammar S, Gavard J. 2011. Evaluation of iron oxide nanoparticle biocompatibility. Int J Nanomed. 6:787–794.
   PubMed Web of Science ®Google Scholar
• Huang H, Lai W, Cui M, Liang L, Lin Y, Fang Q, Liu Y, Xie L. 2016. An evaluation of blood compatibility of silver nanoparticles. Sci Rep. 6:25518. doi: 10.1038/srep25518.
   PubMed Web of Science ®Google Scholar
• Hussain S, Vanoirbeek J, Hoet P. 2012. Interactions of nanomaterials with the immune system. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 4:169–183.
   PubMed Web of Science ®Google Scholar
• Jiao Q, Li L, Mu Q, Zhang Q. 2014. Immunomodulation of nanoparticles in nanomedicine applications. Biomed Res Intl. 2014:426028.
   PubMed Web of Science ®Google Scholar
• Kasyapa C, Ramanadham M. 1992. Alkaline phosphatase activity is expressed only in B-lymphocytes committed to proliferation. Immunol Lett. 31:111–116.
   PubMed Web of Science ®Google Scholar
• Lara H, Garza-Treviño E, Ixtepan-Turrent L, Singh D. 2011. Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds. J Nanobiotechnology. 9:30. doi: 10.1186/1477-3155-9-30.
   PubMed Web of Science ®Google Scholar
• Lee P, Meisel D. 1982. Adsorption and surface-enhanced Raman dyes on silver and gold sols. J Phys Chem. 86:3391–3395.
   Web of Science ®Google Scholar
• Liptrott N, Kendall E, Nieves D, Farrell J, Rannard S, Fernig D, Owen A. 2014. Partial mitigation of gold nanoparticle interactions with human lymphocytes by surface functionalization with a 'mixed matrix'. Nanomedicine. 9:2467–2479.
   PubMed Web of Science ®Google Scholar
• Liu Y, Chen Z, Wang J. 2011. Systematic evaluation of biocompatibility of magnetic Fe3O4 nanoparticles with six different mammalian cell lines. J Nanopart Res. 13:199–212.
   Web of Science ®Google Scholar
• Liu X, Huang N, Li H, Jin Q, Ji J. 2013. Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells. Langmuir. 29:9138–9148.
   PubMed Web of Science ®Google Scholar
• Loza K, Diendorf J, Sengstock C, Ruiz-Gonzalez L, Gonzalez-Calbet J, Vallet-Regi M, Koller M, Epple M. 2014. Dissolution and biological effects of silver nanoparticles in biological media. J Mater Chem. 2:1634–1643.
   PubMed Web of Science ®Google Scholar
• Małaczewska J. 2015. The splenocyte proliferative response and cytokine secretion in mice after oral administration of commercial gold nano-colloid. Pol J Vet Sci. 18:181–189.
   PubMed Web of Science ®Google Scholar
• Mironava T, Hadjiargyrou M, Simon M, Jurukovski V, Rafailovich M. 2010. Gold nanoparticles cellular toxicity and recovery: Effect of size, concentration and exposure time. Nanotoxicology. 4:120–137.
   PubMed Web of Science ®Google Scholar
• Mukherjee P, Bhattacharya R, Bone N, Lee Y, Patra C, Wang S, Lu L, Secreto C, Banerjee P, Yaszemski M, et al. 2007. Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): Enhancing apoptosis. J Nanobiotechnol. 5:4. doi: 10.1186/1477-3155-5-4.
   PubMedGoogle Scholar
• Nune S, Gunda P, Thallapally P, Lin Y, Forrest M, Berkland C. 2009. Nanoparticles for biomedical imaging. Expert Opin Drug Deliv. 6:1175–1194.
   PubMed Web of Science ®Google Scholar
• Rai M, Yadav A, Aniket G. 2009. Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv. 27:76–83.
   PubMed Web of Science ®Google Scholar
• Sabella S, Carney R, Brunetti V, Malvindi M, Al-Juffali N, Vecchio G, Janes S, Bakr O, Cingolani R, Stellacci F, et al. 2014. A general mechanism for intracellular toxicity of metal-containing nanoparticles. Nanoscale. 6:7052–7061.
   PubMed Web of Science ®Google Scholar
• Tomic S, Dokic J, Vasilijic S, Ogrinc N, Rudolf R, Pelicon P, Vucevic D, Milosavljevic P, Jankovic S, Anzel I, et al. 2014. Size-dependent effects of gold nanoparticles uptake on maturation and anti-tumor functions of human dendritic cells in vitro. PLoS One. 9:e96584. doi: 10.1371/journal.pone.0096584.
   PubMed Web of Science ®Google Scholar
• van der Zande M, Vandebriel R, van Doren E, Kramer E, Rivera Z, Serrano-Rojero C, Gremmer E, Mast J, Peters R, Hollman P, et al. 2012. Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure. ACS Nano. 6:7427–7442.
   PubMed Web of Science ®Google Scholar
• Vance M, Kuiken T, Vejerano E, McGinnis S, Hochella M, Rejeski D, Hull M. 2015. Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory. Beilstein J Nanotechnol. 6:1769–1780.
   PubMed Web of Science ®Google Scholar
• Vergallo C, Panzarini E, Izzo D, Carata E, Mariano S, Buccolieri A, Serra A, Manno D, Dini L. 2014. Cytotoxicity of β-D-glucose coated silver nanoparticles on human lymphocytes. AIP Conf Proc. 1603:78–86.
   Google Scholar
• Villiers C, Freitas H, Couderc R, Villiers M, Marche P. 2010. Analysis of the toxicity of gold nanoparticles on the immune system: Effect on dendritic cell functions. J Nanopart Res. 12:55–60.
   PubMed Web of Science ®Google Scholar
• Zimmerman D, Gregory S, Kern M. 1977. Differentiation of lymphoid cells: The preferential binding of the lipid A moiety of lipopolysaccharide to B-lymphocyte populations. J Immunol. 119:1018–1023.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Wang B, Feng W, Bai C. 2014. Nanotoxicology: Toxicological and biological properties of nanomaterials. Encyclopedia of Life Support Systems; [cited 2016 Aug 10]. Available from: http://www.eolss.net.
   Google Scholar
• Zhornik E, Baranova L, Drozd E, Sudas M, Chau N, Buu N, Dung T, Chizhik S, Volotovski I. 2014. Silver nanoparticles induce lipid peroxidation and morphological changes in human lymphocytes surface. Biophysics. 59:380–386.
   Google Scholar
• Zolnik B, Gonzalez-Fernandez A, Sadrieh N, Dobrovolskaia M. 2010. Nanoparticles and the immune system. Endocrinology. 151:458–465.
   PubMed Web of Science ®Google Scholar