Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure

References

• Bates M, Akbari P, Gilley K, Wagner J, Li N, Kopec A, Wierenga K, Jackson-Humbles D, Brandenberger C, Holian A, et al. 2018. Dietary docosahexaenoic acid prevents silica-induced development of pulmonary ectopic germinal centers and glomerulonephritis in the lupus-prone NZBWF1 mouse. Front Immunol. 9:2002.
   PubMed Web of Science ®Google Scholar
• Bauer C, Kielian T, Wyatt T, Romberger D, West W, Gleason A, Poole J. 2013. Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice. Am J Respir Cell Mol Biol. 48(6):781–789.
   PubMed Web of Science ®Google Scholar
• Bhat S, Massey N, Karriker L, Singh B, Charavaryamath C. 2019. Ethyl pyruvate reduces organic dust-induced airway inflammation by targeting HMGB1-RAGE signaling. Respir Res. 20(1):27.
   PubMedGoogle Scholar
• Cleaver J, You D, Michaud D, Pruneda F, Juarez M, Zhang J, Weill P, Adachi R, Gong L, Moghaddam S, et al. 2014. Lung epithelial cells are essential effectors of inducible resistance to pneumonia. Mucosal Immunol. 7(1):78–88.
   PubMed Web of Science ®Google Scholar
• Dickinson J, Alevy Y, Malvin N, Patel K, Gunsten S, Holtzman M, Stappenbeck T, Brody S. 2016. IL-13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy. 12(2):397–409.
   PubMed Web of Science ®Google Scholar
• Dickinson J, Sweeter J, Staab E, Nelson A, Bailey K, Warren K, Jaramillo A, Dickey B, Poole J. 2019. MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultural organic dust exposure. Am J Physiol Lung Cell Mol Physiol. 316(2):L334–L347.
   PubMed Web of Science ®Google Scholar
• Dickinson J, Sweeter J, Warren K, Ahmad I, de Deken X, Zimmerman M, Brody S. 2018. Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation. Redox Biol. 14:272–284.
   PubMed Web of Science ®Google Scholar
• Fujisawa T, Velichko S, Thai P, Hung L, Huang F, Wu R. 2009. Regulation of airway MUC5AC expression by IL-1β and IL-17A; The NF-κB paradigm. J Immunol. 183(10):6236–6243.
   PubMed Web of Science ®Google Scholar
• Ghosn E, Yang Y, Tung J, Herzenberg L, Herzenberg L. 2008. CD11b expression distinguishes sequential stages of peritoneal B-1 development. Proc Natl Acad Sci USA. 105(13):5195–5200.
   PubMed Web of Science ®Google Scholar
• Janssen W, Stefanski A, Bochner B, Evans C. 2016. Control of lung defense by mucins and macrophages: Ancient defense mechanisms with modern functions. Eur Respir J. 48(4):1201–1214.
   PubMed Web of Science ®Google Scholar
• Johnson A, Harkema J, Nelson A, Dickinson J, Kalil J, Duryee M, Thiele G, Kumar B, Singh A, Gaurav R, et al. 2020. MyD88 regulates a prolonged adaptation response to environmental dust exposure-induced lung disease. Respir Res. 21(1):97.
   PubMed Web of Science ®Google Scholar
• Kelly K, Poole J. 2019. Pollutants in the workplace: Effect on occupational asthma. J Allergy Clin Immunol. 143(6):2014–2015.
   PubMed Web of Science ®Google Scholar
• Mikuls T, Gaurav R, Thiele G, England B, Wolfe M, Shaw B, Bailey K, Wyatt T, Nelson A, Duryee M, et al. 2021. The impact of airborne endotoxin exposure on rheumatoid arthritis-related joint damage, autoantigen expression, autoimmunity, and lung disease. Int Immunopharmacol. 100:108069.
   PubMed Web of Science ®Google Scholar
• Moon H, Kim S, Jeong J, Han S, Jarjour N, Lee H, Abboud-Werner S, Chung S, Choi H, Natarajan V, et al. 2018. Airway epithelial cell-derived colony stimulating factor-1 promotes allergen sensitization. Immunity. 49(2):275–287 e5.
   PubMed Web of Science ®Google Scholar
• Natarajan K, Meganathan V, Mitchell C, Boggaram V. 2019. Organic dust induces inflammatory gene expression in lung epithelial cells via ROS-dependent STAT-3 activation. Am J Physiol Lung Cell Mol Physiol. 317(1):L127–L140.
   PubMed Web of Science ®Google Scholar
• Nordgren T, Bauer C, Heires A, Poole J, Wyatt T, West W, Romberger D. 2015. Maresin-1 reduces airway inflammation associated with acute and repetitive exposures to organic dust. Transl Res. 166(1):57–69.
   PubMed Web of Science ®Google Scholar
• Nordgren T, Friemel T, Heires A, Poole J, Wyatt T, Romberger D. 2014. The omega-3 fatty acid docosahexaenoic acid attenuates organic dust-induced airway inflammation. Nutrients. 6(12):5434–5452.
   PubMed Web of Science ®Google Scholar
• Okubo T, Knoepfler P, Eisenman R, Hogan B. 2005. Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development. 132(6):1363–1374.
   PubMed Web of Science ®Google Scholar
• Poole J, Wyatt T, Oldenburg P, Elliott M, West W, Sisson J, von Essen S, Romberger D. 2009. Intranasal organic dust exposure-induced airway adaptation response marked by persistent lung inflammation and pathology in mice. Am J Physiol Lung Cell Mol Physiol. 296(6):L1085–1095.
   PubMed Web of Science ®Google Scholar
• Poole J, Mikuls T, Duryee M, Warren K, Wyatt T, Nelson A, Romberger D, West W, Thiele G. 2017. A role for B-cells in organic dust induced lung inflammation. Respir Res. 18(1):214.
   PubMedGoogle Scholar
• Poole J, Wyatt T, Kielian T, Oldenburg P, Gleason A, Bauer A, Golden G, West W, Sisson J, Romberger D. 2011. Toll-like receptor 2 regulates organic dust-induced airway inflammation. Am J Respir Cell Mol Biol. 45(4):711–719.
   PubMed Web of Science ®Google Scholar
• Poole J, Gleason A, Bauer C, West W, Alexis N, van Rooijen N, Reynolds S, Romberger D, Kielian T. 2012a. CD11c+/CD11b+ cells are critical for organic dust-elicited murine lung inflammation. Am J Respir Cell Mol Biol. 47(5):652–659.
   PubMed Web of Science ®Google Scholar
• Poole J, Romberger D, Bauer C, Gleason A, Sisson J, Oldenburg P, West W, Wyatt T. 2012b. Protein kinase C epsilon is important in modulating organic-dust-induced airway inflammation. Exp Lung Res. 38(8):383–395.
   PubMed Web of Science ®Google Scholar
• Poole J, Anderson L, Gleason A, West W, Romberger D, Wyatt T. 2015a. Pattern recognition scavenger receptor A/CD204 regulates airway inflammatory homeostasis following organic dust extract exposures. J Immunotoxicol. 12(1):64–73.
   PubMed Web of Science ®Google Scholar
• Poole J, Wyatt T, Romberger D, Staab E, Simet S, Reynolds S, Sisson J, Kielian T. 2015b. MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment. Respir Res. 16:111.
   PubMed Web of Science ®Google Scholar
• Rawlins E, Okubo T, Xue Y, Brass D, Auten R, Hasegawa H, Wang F, Hogan B. 2009. The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell. 4(6):525–534.
   PubMed Web of Science ®Google Scholar
• Romberger D, Heires A, Nordgren T, Souder C, West W, Liu X, Poole J, Toews M, Wyatt T. 2015. Proteases in agricultural dust induce lung inflammation through PAR-1 and PAR-2 activation. Am J Physiol Lung Cell Mol Physiol. 309(4):L388–399.
   PubMed Web of Science ®Google Scholar
• Singh G, Katyal S. 2000. Clara cell proteins. Ann N Y Acad Sci. 923:43–58.
   PubMed Web of Science ®Google Scholar
• Sitaraman S, Martin E, Na CL, Zhao S, Green J, Deshmukh H, Perl A, Bridges J, Xu Y, Weaver T. 2021. Surfactant protein C mutation links post-natal type 2 cell dysfunction to adult disease. JCI Insight. 6(14):e142501.
   PubMed Web of Science ®Google Scholar
• Sweeter J, Kudrna K, Hunt K, Thomes P, Dickey B, Brody S, Dickinson J. 2021. Autophagy of mucin granules contributes to resolution of airway mucous metaplasia. Sci Rep. 11(1):13037.
   PubMed Web of Science ®Google Scholar
• Ulu A, Burr A, Heires AJ, Pavlik J, Larsen T, Perez P, Bravo C, DiPatrizio N, Baack M, Romberger D, et al. 2021. A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts. J Nutr Biochem. 97:108797.
   PubMed Web of Science ®Google Scholar
• Wang X. 2009. Cre transgenic mouse lines. Meth Mol Biol. 561:265–273.
   PubMedGoogle Scholar
• Wyatt T, Nemecek M, Chandra D, DeVasure JM, Nelson A, Romberger D, Poole J. 2020. Organic dust-induced lung injury and repair: bi-directional regulation by TNFα and IL-10. J Immunotoxicol. 17(1):153–162.
   PubMed Web of Science ®Google Scholar
• Wyatt T, Poole J, Nordgren T, DeVasure J, Heires A, Bailey K, Romberger D. 2014. cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 307(8):L643–651.
   PubMed Web of Science ®Google Scholar