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Articles

Lack of Association Between TNF-α, IFN-γ, IL-10 Gene Polymorphisms and Rheumatic Heart Disease in South Indian Population

ORCID Icon, , , &
Pages 309-318 | Received 31 May 2018, Accepted 20 Jun 2018, Published online: 24 Sep 2018

References

  • Guilherme L, Kalil J, Cunningham M. Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease. Autoimmunity. 2006;39(1):31–9.
  • Cunningham MW. Rheumatic fever, autoimmunity, and molecular mimicry: the streptococcal connection. Int Rev Immunol. 2014;33(4):314–29.
  • Guilherme L, Cury P, Demarchi LM, Coelho V, Abel L, Lopez AP, Oshiro SE, Aliotti S, Cunha-Neto E, Pomerantzeff PM, et al. Rheumatic heart disease: proinflammatory cytokines play a role in the progression and maintenance of valvular lesions. Am J Pathol. 2004;165(5):1583–91.
  • Toor D, Vohra H. Immune responsiveness during disease progression from acute rheumatic fever to chronic rheumatic heart disease. Microbes Infect. 2012;14(12):1111–7.
  • De Nardin E. Genetic polymorphisms and immune responses. Immunol Invest. 2009;38(3–4):198–202.
  • Abubakar II, Tillmann T, Banerjee A. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117–71.
  • Elahi MM, Asotra K, Matata BM, Mastana SS. Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease. Biochim Biophys Acta. 2009;1792(3):163–67.
  • Wilson AG, Symons JA, Mcdowell TL, Mcdevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA. 1997;94(7):3195–99.
  • Gupta R, Kapuria V, Das SN. Single nucleotide polymorphisms in TNF-α, TNFR2 gene and TNF-α production in Asian Indians. Immunol Invest. 2009;38(3–4):240–54.
  • Pravica V, Asderakis A, Perrey C, Hajeer A, Sinnott PJ, Hutchinson IV. In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene. Eur J Immunogenet. 1999;26(1):1–3.
  • Pravica V, Perrey C, Stevens A, Lee JH, Hutchinson IV. A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. Hum Immunol. 2000;61(9):863–66.
  • Saraiva M, O'garra A. The regulation of IL-10 production by immune cells. Nat Rev Immunol. 2010;10(3):170–81.
  • Couper KN, Blount DG, Riley EM. IL-10: the master regulator of immunity to infection. J Immunol. 2008;180(9):5771–7.
  • Iyer SS, Cheng G. Role of Interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol. 2012;32(1):23–63.
  • Trifunović J, Miller L, Debeljak Ž, Horvat V. Pathologic patterns of interleukin 10 expression-a review. Biochem Med. (Zagreb) 2015;25(1):36–48.
  • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16(3):1215.
  • Milicic A, Lindheimer F, Laval S, Rudwaleit M, Ackerman H, Wordsworth P, Hohler T, Brown MA. Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis. Genes Immun. 2000. 1(7):418–22.
  • Mullighan CG, Marshall SE, Bunce M, Welsh KI. Variation in immunoregulatory genes determines the clinical phenotype of common variable immunodeficiency. Genes Immun. 1999;1(2):137–48.
  • Barrett JC, Fry B, Maller JD, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21(2):263–65.
  • Hernandez-Pacheco G, Flores-Dominguez C, Rodriguez-Perez JM, Pérez-Hernández N, Fragoso JM, Saul A, Alvarez-León E, Granados J, Reyes PA, Vargas-Alarcón G. Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with rheumatic heart disease. J Autoimmun. 2003;21(1):59–63.
  • Sallakci N, Akcurin G, Koksoy S, Kardelen F, Uguz A, Coskun M, Ertug H, Yegin O. TNF-alpha G-308A polymorphism is associated with rheumatic fever and correlates with increased TNF-alpha production. J Autoimmun. 2005;25(2):150–54.
  • Ramasawmy R, Fae KC, Spina G, Victora GD, Tanaka AC, Palácios SA, Hounie AG, Miguel EC, Oshiro SE, Goldberg AC, et al. Association of polymorphisms within the promoter region of the tumor necrosis factor alpha with clinical outcomes of rheumatic fever. Mol Immunol. 2007;44(8):1873–78.
  • Settin A, Abdel-Hady H, El-Baz R, Saber I. Gene polymorphisms of TNF-alpha(-308), IL-10(-1082), IL-6(-174), and IL-1Ra(VNTR) related to susceptibility and severity of rheumatic heart disease. Pediatr Cardiol. 2007;28(5):363–71.
  • Mohamed AA, Rashed LA, Shaker SM, Ammar RI. Association of tumor necrosis factor-alpha polymorphismswith susceptibility and clinical outcomes of rheumatic heart disease. Saudi Med J. 2010;31(6):644–49.
  • Rehman S, Akhtar N, Saba N, Munir S, Ahmed W, Mohyuddin A, Khanum A. A study on the association of TNF-α(-308), IL-6(-174), IL-10(-1082) and IL-1Ra(VNTR) gene polymorphisms with rheumatic heart disease in Pakistani patients. Cytokine. 2013;61(2):527–31.
  • Zheng RL, Zhang H, Jiang WL. Tumor necrosis factor-alpha 308G > A polymorphism and risk of rheumatic heart disease: a meta-analysis. Sci Rep. 2014;4:4731.
  • Berdeli A, Tabel Y, Celik HA, Ozyürek R, Dogrusoz B, Aydin HH. Lack of association between TNFalpha gene polymorphism at position -308 and risk of acute rheumatic fever in Turkish patients. Scand J Rheumatol. 2006;35(1):44–7.
  • Col-Araz N, Pehlivan S, Baspinar O, Oguzkan-Balci S, Sever T, Balat A. Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children. Eur J Pediatr. 2012;171(7):1103–8.
  • Gupta U, Mir SS, Garg N, Agarwal SK, Pande S, Mittal B. Association study of inflammatory genes with rheumatic heart disease in North Indian population: a multi-analytical approach. Immunol Lett. 2016;174:53–62.
  • Guilherme L, Cunha-Neto E, Tanaka AC, Dulphy N, Toubert A, Kalil J. Heart-directed autoimmunity: the case of rheumatic fever. J Autoimmun. 2001;16(3):363–7.
  • Nasuti JF, Zhang PJ, Feldman MD, Pasha T, Khurana JS, Gorman JH III, Gorman RC, Narula J, Narula N. Fibrillin and other matrix proteins in mitral valve prolapse syndrome. Ann Thorac Surg. 2004;77(2):532–6.
  • Hayek E, Gring CN, Griffin BD. Mitral valve prolapse. Lancet. 2005;365(9458):507–18.
  • Faé KC, da Silva DD, Oshiro SE, Tanaka AC, Pomerantzeff PM, Douay C, Charron D, Toubert A, Cunningham MW, Kalil J, et al. Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease. J Immunol. 2006;176(9):5662–70.
  • Guilherme L, Fae KC, Oshiro SE, Tanaka AC, Pomerantzeff PMA, Kalil J. Rheumatic fever: how S. pyogenes-primed peripheral T cells trigger heart valve lesions. Ann NY Acad Sci. 2005;1051:132–40.
  • Teker E, Akadam-Teker AB, Ozturk O, Eronat AP, Yalin K, Golcuk SE, Bugra Z. Association between the interferon gamma 874 T/A polymorphism and the severity of valvular damage in patients with rheumatic heart disease. Biochem Genet. 2018;56:225–34.
  • Lee YH, Bae SC. Association between interferon-γ+ 874 T/A polymorphism and susceptibility to autoimmune diseases: a meta-analysis. Lupus. 2015;25(7):710–8.
  • Taylor A, Verhagen J, Blaser K, Akdis M, Akdis CA. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-b: the role of T regulatory cells. Immunology 2006;117(4):433–42.
  • Tawfik E, El-Salam MA, Abdulkarem A, Yosseri M. Gene polymorphisms of TNF- α and IL-10 related to rheumatic heart disease. Egypt J Med Hum Genet. 2010;11(1):33–45.
  • Abdallah AM, Alnuzha A, Al-Mazroea AH, Eldardear AE, AlSamman AY, Almohammadi Y, Al-Harbi KM. IL10 promoter polymorphisms are associated with rheumatic heart disease in Saudi Arabian patients. Pediatr Cardiol. 2015;37(1):1–7.
  • Yousry SM, Sedky Y, Sobieh A. Association of IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms with risk of mitral valve disease in children with rheumatic heart disease. Cardiol Young. 2016;26(7):1290–6.
  • Paladino N, Fainboim H, Theiler G, Schroder T, Muñoz AE, Flores AC, Galdame O, Fainboim L. Gender susceptibility to chronic hepatitis C virus infection associated with interleukin 10 promoter polymorphism. J Virol. 2006;80(18):9144–50.
  • Tedde A, Laura Putignano A, Bagnoli S, Congregati C, Milla M, Sorbi S, Genuardi M, Papi L. Interleukin-10 promoter polymorphisms influence susceptibility to ulcerative colitis in a gender-specific manner. Scand J Gastroenterol. 2008;43(6):712–8.
  • Nussinovitch U, Shoenfeld Y. The role of gender and organ specific autoimmunity. Autoimmun Rev. 2012;11(6–7):A377–85.

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