TP53-dependent autophagy links the ATR-CHEK1 axis activation to proinflammatory VEGFA production in human bronchial epithelial cells exposed to fine particulate matter (PM2.5)

References

• Suhaimi NF, Jalaludin J. Biomarker as a research tool in linking exposure to air particles and respiratory health. Biomed Res Int 2015; 2015:962853; PMID:25984536; http://dx.doi.org/10.1155/2015/962853
   PubMed Web of Science ®Google Scholar
• Wang C, Tu Y, Yu Z, Lu R. PM2.5 and cardiovascular diseases in the elderly: an overview. Int J Environ Res Pub Health 2015; 12:8187-97; PMID:26193289; http://dx.doi.org/10.3390/ijerph120708187
   PubMed Web of Science ®Google Scholar
• Nogueira JB. Poluição atmosférica e doenças cardiovasculares. Rev Port Cardiol 2009; 28:715-33; PMID:19697799
   PubMedGoogle Scholar
• Veranth JM, Moss TA, Chow JC, Labban R, Nichols WK, Walton JC, Watson JG, Yost GS. Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter. Environ Health Perspect 2005; 114:341-49; PMID:16507455; http://dx.doi.org/10.1289/ehp.8360
   PubMed Web of Science ®Google Scholar
• Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K. Transcriptomic analyses of the biological effects of airborne PM2.5 exposure on human bronchial epithelial cells. PloS one 2015; 10:e0138267; PMID:26382838; http://dx.doi.org/10.1371/journal.pone.0138267
   PubMed Web of Science ®Google Scholar
• Siponen T, Yli-Tuomi T, Aurela M, Dufva H, Hillamo R, Hirvonen MR, Huttunen K, Pekkanen J, Pennanen A, Salonen I, et al. Source-specific fine particulate air pollution and systemic inflammation in ischaemic heart disease patients. Occup Environ Med 2015; 72:277-83; PMID:25479755; http://dx.doi.org/10.1136/oemed-2014-102240
   PubMed Web of Science ®Google Scholar
• Wirawan E, Vanden Berghe T, Lippens S, Agostinis P, Vandenabeele P. Autophagy: for better or for worse. Cell Res 2012; 22:43-61; PMID:21912435; http://dx.doi.org/10.1038/cr.2011.152
   PubMed Web of Science ®Google Scholar
• Xu Y, Eissa NT. Autophagy in innate and adaptive immunity. Proc Am Thorac Soc 2010; 7:22-8; PMID:20160145; http://dx.doi.org/10.1513/pats.200909-103JS
   PubMedGoogle Scholar
• Das G, Shravage BV, Baehrecke EH. Regulation and function of autophagy during cell survival and cell death. Cold Spring Harb Perspect Biol 2012; 4:a008813; PMID:22661635; http://dx.doi.org/10.1101/cshperspect.a008813
   PubMed Web of Science ®Google Scholar
• Mah LY, Ryan KM. Autophagy and cancer. Cold Spring Harb Perspect Biol 2012; 4:a008821; PMID:22166310; http://dx.doi.org/10.1101/cshperspect.a008821
   PubMed Web of Science ®Google Scholar
• Lapaquette P, Guzzo J, Bretillon L, Bringer MA. Cellular and molecular connections between autophagy and inflammation. Mediat Inflamm 2015; 2015:398483; PMID:26221063; http://dx.doi.org/10.1155/2015/398483
   PubMed Web of Science ®Google Scholar
• Jo EK, Shin DM, Choi AM. Autophagy: cellular defense to excessive inflammation. Microbes Infect 2012; 14:119-25; PMID:21924374; http://dx.doi.org/10.1016/j.micinf.2011.08.014
   PubMed Web of Science ®Google Scholar
• Mizumura K, Choi AMK, Ryter SW. Emerging role of selective autophagy in human diseases. Front Pharmacol 2014; 5:00244; PMID:25414669; http://dx.doi.org/10.3389/fphar.2014.00244
   PubMed Web of Science ®Google Scholar
• Dickinson JD, Alevy Y, Malvin NP, Patel KK, Gunsten SP, Holtzman MJ, Stappenbeck TS, Brody SL. IL13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy 2015; 2015:1056967
   Google Scholar
• Poon A, Eidelman D, Laprise C, Hamid Q. ATG5, autophagy and lung function in asthma. Autophagy 2012; 8:694-95; PMID:22498476; http://dx.doi.org/10.4161/auto.19315
   PubMed Web of Science ®Google Scholar
• Cho IH, Choi YJ, Gong JH, Shin D, Kang MK, Kang YH. Astragalin inhibits autophagy-associated airway epithelial fibrosis. Resp Res 2015; 16:51; PMID: 25895672; http://dx.doi.org/10.1186/s12931-015-0211-9
   PubMed Web of Science ®Google Scholar
• Wu Q, Jiang D, Huang C, van Dyk LF, Li L, Chu HW. Trehalose-mediated autophagy impairs the anti-viral function of human primary airway epithelial cells. PloS one 2015; 10:e0124524; PMID:25879848; http://dx.doi.org/10.1371/journal.pone.0124524
   PubMed Web of Science ®Google Scholar
• Lee CG, Ma B, Takyar S, Ahangari F, DelaCruz C, He CH, Elias JA. Studies of vascular endothelial growth factor in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2011; 8:512-15; PMID:22052929; http://dx.doi.org/10.1513/pats.201102-018MW
   PubMedGoogle Scholar
• Tuder RM, Yun JH. Vascular endothelial growth factor in the lung: friend or foe. Curr Opin Pharmacol 2008; 8:255-60; PMID:18468486; http://dx.doi.org/10.1016/j.coph.2008.03.003
   PubMed Web of Science ®Google Scholar
• Matsune S. Allergic rhinitis and vascular endothelial growth factor. J Nippon Med Sch 2012; 79:170-75; PMID:22791116; http://dx.doi.org/10.1272/jnms.79.170
   PubMed Web of Science ®Google Scholar
• Haigh JJ. Role of VEGF in organogenesis. Organogenesis 2008; 4:247-56; PMID:19337405; http://dx.doi.org/10.4161/org.4.4.7415
   PubMedGoogle Scholar
• Dong W, Li Y, Gao M, Hu M, Li X, Mai S, Guo N, Yuan S, Song L. IKKalpha contributes to UVB-induced VEGF expression by regulating AP-1 transactivation. Nucleic Acids Res 2012; 40:2940-55; PMID:22169952; http://dx.doi.org/10.1093/nar/gkr1216
   PubMed Web of Science ®Google Scholar
• Loos B, Toit Ad, Hofmeyr J-HS. Defining and measuring autophagosome flux-concept and reality. Autophagy 2014; 10:2087-96; PMID:25484088; http://dx.doi.org/10.4161/15548627.2014.973338
   PubMed Web of Science ®Google Scholar
• Hao Q, Cho W. Battle against cancer: an everlasting saga of p53. Int J Mol Sci 2014; 15:22109-27; PMID:25470027; http://dx.doi.org/10.3390/ijms151222109
   PubMed Web of Science ®Google Scholar
• Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126:121-34; PMID:16839881; http://dx.doi.org/10.1016/j.cell.2006.05.034
   PubMed Web of Science ®Google Scholar
• Benada J, Macurek L. Targeting the checkpoint to kill cancer cells. Biomolecules 2015; 5:1912-37; PMID:26295265; http://dx.doi.org/10.3390/biom5031912
   PubMed Web of Science ®Google Scholar
• Karnitz LM, Zou L. Molecular pathways: targeting ATR in cancer therapy. Clin Can Res 2015; 21:4780-85; PMID:26362996; http://dx.doi.org/10.1158/1078-0432.CCR-15-0479
   PubMed Web of Science ®Google Scholar
• Driscoll KE. TNF alpha and MIP-2: role in particle-induced inflammation and regulation by oxidative stress. Toxicol Lett 2000; 112–113:177-84; PMID:10720729
   PubMed Web of Science ®Google Scholar
• Kaser A, Blumberg RS. Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease. Semi Immunol 2009; 21:156-63; PMID:19237300; http://dx.doi.org/10.1016/j.smim.2009.01.001
   PubMed Web of Science ®Google Scholar
• Brest P, Corcelle EA, Cesaro A, Chargui A, Belaïd A, Klionsky DJ, Vouret-Craviari V, Hebuterne X, Hofman P, Mograbi B. Autophagy and crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer. Curr Mol Med 2010; 10:486-502; PMID:20540703; http://dx.doi.org/10.2174/156652410791608252
   PubMed Web of Science ®Google Scholar
• Harris J. Autophagy and cytokines. Cytokine 2011; 56:140-44; PMID:21889357; http://dx.doi.org/10.1016/j.cyto.2011.08.022
   PubMed Web of Science ®Google Scholar
• Chang YP, Chen CL, Chen SO, Lin YS, Tsai CC, Huang WC, Wang CY, Hsieh CY, Choi PC, Lin CF. Autophagy facilitates an IFN-gamma response and signal transduction. Microbes Infect 2011; 13:888-94; PMID:21664983; http://dx.doi.org/10.1016/j.micinf.2011.05.008
   PubMed Web of Science ®Google Scholar
• Sui X, Jin L, Huang X, Geng S, He C, Hu X. p53 signaling and autophagy in cancer: a revolutionary strategy could be developed for cancer treatment. Autophagy 2014; 7:565-71; PMID:21099252; http://dx.doi.org/10.4161/auto.7.6.14073
   PubMed Web of Science ®Google Scholar
• Crighton D, Wilkinson S, Ryan KM. DRAM links autophagy to p53 and programmed cell death. Autophagy 2014; 3:72-74; PMID:17102582; http://dx.doi.org/10.4161/auto.3438
   PubMed Web of Science ®Google Scholar
• Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN. Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase. J Immunol 2014; 192:5933-42; PMID:24799566; http://dx.doi.org/10.4049/jimmunol.1303470
   PubMed Web of Science ®Google Scholar
• Frankenberger S, Davari K, Fischer-Burkart S, Bottcher K, Tomi NS, Zimber-Strobl U, Jungnickel B. Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res 2014; 42:3666-74; PMID:24423870; http://dx.doi.org/10.1093/nar/gkt1378
   PubMed Web of Science ®Google Scholar
• Gasser S, Orsulic S, Brown EJ, Raulet DH. The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 2005; 436:1186-90; PMID:15995699; http://dx.doi.org/10.1038/nature03884
   PubMed Web of Science ®Google Scholar
• Tang MLF, Khan MKN, Croxford JL, Tan KW, Angeli V, Gasser S. The DNA damage response induces antigen presenting cell-like functions in fibroblast. Eur J Immunol 2014; 44:1108-18; PMID:24375454; http://dx.doi.org/10.1002/eji.201343781
   PubMed Web of Science ®Google Scholar
• Gao M, Li X, Dong W, Jin R, Ma H, Yang P, Hu M, Li Y, Hao Y, Yuan S, et al. Ribosomal protein S7 regulates arsenite-induced GADD45alpha expression by attenuating MDM2-mediated GADD45alpha ubiquitination and degradation. Nucleic Acids Res 2013; 41:5210-22; PMID:23563151; http://dx.doi.org/10.1093/nar/gkt223
   PubMed Web of Science ®Google Scholar
• Tan Q, Wang H, Hu Y, Hu M, Li X, Aodengqimuge, Ma Y, Wei C, Song L. Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy. Cancer Sci 2015; 106:1023-32; PMID:26041409; http://dx.doi.org/10.1111/cas.12712
   PubMed Web of Science ®Google Scholar