References
- Bardos J, Hercz D, Friedenthal J, et al. A national survey on public perceptions of miscarriage. Obstet Gynecol. 2015;125:1313–1320.
- Rancati G, Moffat J, Typas A, et al. Emerging and evolving concepts in gene essentiality. Nat Rev Genet. 2018;19:34–49.
- Bartha I, di Iulio J, Venter JC, et al. Human gene essentiality. Nat Rev Genet. 2018;19:51–62.
- Wang T, Birsoy K, Hughes NW, et al. Identification and characterization of essential genes in the human genome. Science. 2015;350:1096–1101.
- Scheidecker S, Etard C, Haren L, et al. Mutations in TUBGCP4 alter microtubule organization via the gamma-tubulin ring complex in autosomal-recessive microcephaly with chorioretinopathy. Am J Hum Genet. 2015;96:666–674.
- Coutts AS, La Thangue NB. Regulation of actin nucleation and autophagosome formation. Cell Mol Life Sci. 2016;73:3249–3263.
- Li Z, Li H, Xu X, et al. Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina. Cell Death Differ. 2019;26.
- Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol. 2010;12:814–822.
- Felszeghy S, Viiri J, Paterno JJ, et al. Loss of NRF-2 and PGC-1alpha genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration. Redox Biol. 2019;20:1–12.
- Yao J, Jia L, Khan N, et al. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 2015;11:939–953.
- Luo M, Zhao X, Song Y, et al. Nuclear autophagy: an evolutionarily conserved mechanism of nuclear degradation in the cytoplasm. Autophagy. 2016;12:1973–1983.
- Chen Y, Sawada O, Kohno H, et al. Autophagy protects the retina from light-induced degeneration. J Biol Chem. 2013;288:7506–7518.