Reference
- Fan XY, Guo L, Chen LN, et al. Reduction of mtDNA heteroplasmy in mitochondrial replacement therapy by inducing forced mitophagy. Nat Biomed Eng. 2022;6:339–350.
Autophagic Punctum
SQSTM1 and its MAP1LC3B-binding domain induce forced mitophagy to degrade mitochondrial carryover during mitochondrial replacement therapy
Xiao-Yan Fana Fertility Preservation Lab, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
https://orcid.org/0000-0003-4045-6136View further author information
https://orcid.org/0000-0003-4045-6136View further author information, Shen Yinb College of Life Sciences, Key Laboratory of Animal Reproduction and Biotechnology in Universities of Shandong, Qingdao Agricultural University, Qingdao, ChinaCorrespondence[email protected]
https://orcid.org/0000-0003-4792-7885View further author information
https://orcid.org/0000-0003-4792-7885View further author information & Shi-Ming Luoa Fertility Preservation Lab, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, ChinaCorrespondence[email protected]
https://orcid.org/0000-0002-8874-1510View further author information
https://orcid.org/0000-0002-8874-1510View further author information