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Letter to the Editor

Reply to Hoegberg et al.: letter in response to “lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis”

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Pages 1021-1022 | Received 17 Apr 2017, Accepted 27 Apr 2017, Published online: 23 May 2017

References

  • Fettiplace MR, McCabe DJ. Lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis. Clin Toxicol. Forthcoming 2017. doi: 10.1080/15563650.2017.1288911
  • Buckenmaier CC, Capacchione J, Mielke AR, et al. The effect of lipid emulsion infusion on postmortem ropivacaine concentrations in swine: endeavoring to comprehend a soldier’s death. Anesth Analg. 2012;114:894–900.
  • Bedocs P, Capacchione J, Potts L, et al. Hypersensitivity Reactions to Intravenous Lipid Emulsion in swine: relevance for lipid resuscitation studies. Anesth Analg. 2014;119:1094–1101.
  • Fettiplace MR, Lis K, Ripper R, et al. Multi-modal contributions to detoxification of acute pharmacotoxicity by a triglyceride micro-emulsion. J Control Release. 2015;198:62–70.
  • Fettiplace MR, Kowal K, Ripper R, et al. Insulin signaling in bupivacaine-induced cardiac toxicity: sensitization during recovery and potentiation by lipid emulsion. Anesthesiology. 2016;124:428–442.
  • Dureau P, Charbit B, Nicolas N, et al. Effect of Intralipid® on the dose of ropivacaine or levobupivacaine tolerated by volunteers: a clinical and pharmacokinetic study. Anesthesiology. 2016;125:474–483.
  • Heinonen JA, Litonius E, Salmi T, et al. Intravenous lipid emulsion given to volunteers does not affect symptoms of lidocaine brain toxicity. Basic Clin Pharmacol Toxicol. 2015;116:378–383.
  • Albright G. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology. 1979;51:285–287.
  • Butterworth IVJF, Brownlow RC, Leith JP, et al. Bupivacaine inhibits cyclic-3’,5’-adenosine monophosphate production. A possible contributing factor to cardiovascular toxicity. Anesthesiology. 1993;79:88–95.

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