364
Views
3
CrossRef citations to date
0
Altmetric
Letters in Response to Articles & Replies

Understanding the risk of seizure in tramadol overdose: still a long way to go

, &
Pages 1161-1162 | Received 25 Feb 2019, Accepted 01 Mar 2019, Published online: 20 Mar 2019

References

  • Murray BP, Carpenter JE, Dunkley CA, et al. Seizures in tramadol overdoses reported in the ToxIC registry: predisposing factors and the role of naloxone. Clin Toxicol. 2019;24:1–5.
  • Lagard C, Chevillard L, Malissin I, et al. Mechanisms of tramadol-related neurotoxicity in the rat: Does diazepam/tramadol combination play a worsening role in overdose? Toxicol Appl Pharmacol. 2016;310:108–119.
  • Fujimoto Y, Funao T, Suehiro K, et al. Brain serotonin content regulates the manifestation of tramadol-induced seizures in rats: disparity between tramadol-induced seizure and serotonin syndrome. Anesthesiology. 2015;122:178–189.
  • Beaune S, Callebert J, Baud FJ, et al. Mechanisms of high-dose citalopram-induced death in a rat model. Toxicology. 2012;302:248–254.
  • Lagard C, Malissin I, Indja W, et al. Is naloxone the best antidote to reverse tramadol-induced neuro-respiratory toxicity in overdose? An experimental investigation in the rat. Clin Toxicol. 2018;56:737–743.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.