References
- Yoon E, Babar A, Choudhary M, et al. Acetaminophen-induced hepatotoxicity: a comprehensive update. J Clin Transl Hepatol. 2016;4(2):131–142.
- Rumack BH, Bateman DN. Acetaminophen and acetylcysteine dose and duration: past, present and future. Clin Toxicol. 2012;50(2):91–98.
- Smilkstein MJ, Knapp GL, Kulig KW, et al. Efficacy of oral N-Acetylcysteine in the treatment of acetaminophen overdose. N Engl J Med. 1988;319(24):1557–1562.
- Lin JH, Levy G. Sulfate depletion after acetaminophen administration and replenishment by infusion of sodium sulfate or N-acetylcysteine in rats. Biochem Pharmacol. 1981;30(19):2723–2725.
- Rumack BH, Peterson RC, Koch GG, et al. Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment. Arch Intern Med. 1981;141(3 Spec No):380–385.
- Marks DJB, Dargan PI, Archer JRH, et al. Outcomes from massive paracetamol overdose: a retrospective observational study. Br J Clin Pharmacol. 2017;83(6):1263–1272.
- Wang GS, Monte A, Bagdure D, et al. Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose. Pediatrics. 2011;127(4):e1077–1080.
- Chiew AL, Isbister GK, Kirby KA, et al. Massive paracetamol overdose: an observational study of the effect of activated charcoal and increased acetylcysteine dose (ATOM-2). Clin Toxicol. 2017;55(10):1055–1065.
- Downs JW, Cumpston KL, Kershner EK, et al. Clinical outcome of massive acetaminophen overdose treated with standard-dose N-acetylcysteine. Clin Toxicol. 2021;0(0):1–8.
- Perry HE, Shannon MW. Efficacy of oral versus intravenous N-acetylcysteine in acetaminophen overdose: Results of an open-label, clinical trial. J Pediatr. 1998;132(1):149–152.
- Buckley NA, Whyte IM, O'Connell DL, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759–767.
- Cumberland Pharmaceuticals Inc. ACETADOTE (acetylcysteine) Injection [Package Insert]. U.S. Food and Drug Administration; 2013. [cited 2021 May 14]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021539s012lbl.pdf.
- Prescott L. Kinetics and metabolism of paracetamol and phenacetin. Br J Clin Pharmacol. 1980;10 Suppl 2(2S):291S–298S.
- Doyon S, Klein-Schwartz W. Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdose. Acad Emerg Med. 2009;16(1):34–39.
- Singer AJ, Carracio TR, Mofenson HC. The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction. Ann Emerg Med. 1995;26(1):49–53.
- Green TJ, Sivilotti MLA, Langmann C, et al. When do the aminotransferases rise after acute acetaminophen overdose? Clin Toxicol. 2010;48(8):787–792.