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Letters to the Editor: Original scientific contribution

Excess baggage in describing acetylcysteine regimens

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Pages 88-89 | Received 06 Oct 2022, Accepted 25 Nov 2022, Published online: 09 Dec 2022

References

  • Hoffman RS. Acetylcysteine for paracetamol: will one size ever fit all? EClinicalMedicine. 2020;20:100314.
  • McNulty R, Lim JME, Chandru P, et al. Fewer adverse effects with a modified two-bag acetylcysteine protocol in paracetamol overdose. Clin Toxicol. 2018;56(7):618–621.
  • O’Callaghan C, Graudins A, Wong A. A two-bag acetylcysteine regimen is associated with shorter delays and interruptions in the treatment of paracetamol overdose. Clin Toxicol. 2022;60(3):319–323.
  • Baumgartner K, Filip A, Liss D, et al. N-acetylcysteine for acetaminophen toxicity: the one-bag regimen. Br J Clin Pharmacol. 2021;87(5):2399–2400.
  • Shah KR, Beuhler MC. Single bag high dose intravenous N-acetylcysteine associated with decreased hepatotoxicity compared to triple bag intravenous N-acetylcysteine in high-risk acetaminophen ingestions. Clin Toxicol. 2022;60(4):493–498.

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