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Original Articles

Optimization of the extraction conditions and dermal toxicity of oil body fused with acidic fibroblast growth factor (OLAF)

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Pages 221-231 | Received 07 Oct 2020, Accepted 12 May 2021, Published online: 12 Jul 2021

References

  • Neupane R, Boddu SHS, Renukuntla J, et al. Alternatives to biological skin in permeation studies: current trends and possibilities. Pharmaceutics 2020;12: 152.
  • Bakshi P, Vora D, Hemmady K, et al. Iontophoretic skin delivery systems: success and failures. Int J Pharm 2020;586:119584.
  • Li WQ, Yang J, Cai JB, et al. Oil body-bound oleosin-rhFGF-10: a novel drug delivery system that improves skin penetration to accelerate wound healing and hair growth in mice. Int J Mol Sci 2017;18: 2177.
  • Nykiforuk CL, Boothe JG, Murray EW, et al. Transgenic expression and recovery of biologically active recombinant human insulin from Arabidopsis thaliana seeds. Plant Biotechnol J 2006;4:77–85.
  • Xu MY, Liu DH, Li GQ. Cloning of soybean 24 kda oleosin gene and its transient expression as a carrier for foreign protein. Agri Sci China 2004;3:321–329.
  • Siloto RMP, Findlay K, Lopez VA, et al. The accumulation of oleosins determines the size of seed oilbodies in Arabidopsis. Plant Cell 2006;18:1961–1974.
  • Yi SY, Yang J, Huang J, et al. Expression of bioactive recombinant human fibroblast growth factor 9 in oil bodies of Arabidopsis thaliana. Protein Expr Purif 2015;116:127–132.
  • Bhatla SC, Kaushik V, Yadav MK. Use of oil bodies and oleosins in recombinant protein production and other biotechnological applications. Biotechnol Adv 2010;28:293–300.
  • Nikiforidis CV. Structure and functions of oleosomes (oil bodies). Adv Colloid Interface Sci 2019;274:102039.
  • Yang J, Guan LL, Guo YX, et al. Expression of biologically recombinant human acidic fibroblast growth factor in Arabidopsis thaliana seeds via oleosin fusion technology. Gene 2015;566:89–94.
  • Xu SQ, Qin Y, Wang CJ, et al. Recombinant human acid fibroblast growth factor accelerates skin wound healing in diabetic rats through promoting fibroblast proliferation and angiogenesis. Int J Clin Exp Med 2016;9:9161–9169.
  • Liu YM, Yu FL, Zhang BB, et al. Improving the protective effects of aFGF for peripheral nerve injury repair using sulfated chitooligosaccharides. Asian J Pharm Sci 2019;14:511–520.
  • Nham SU, Kim HS, Lee YI. Overexpression and purification of full-length acidic fibroblast growth factor in E. coli. Biotechnol Lett 1994;16:661–666.
  • Fantoni A, Bill RM, Gustafsson L, et al. Improved yields of full-length functional human FGF1 can be achieved using the methylotrophic yeast Pichia pastoris. Protein Expr Purif 2007;52:31–39.
  • Belch J, Hiatt WR, Baumgartner I, et al. Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia. Lancet 2011;377:1929–1937.
  • Kanno A, Leite LCD, Pereira LR, et al. Optimization and scale-up production of Zika virus Delta NS1 in Escherichia coli: application of response surface methodology. AMB Express 2020;10:1–13.
  • Wei SL, Huang JN, Zhang LX, et al. Physicochemical properties and stabilities of crude and purified oil bodies extracted from high oleic peanuts. Eur J Lipidence Technol 2020;122: 1900183.
  • CFDA,. Technical research guidelines for acute dermal toxicity study. Beijing: China Food and Drug Administration (CFDA); 2014.
  • OECD. OECD guideline for acute dermal irritation/corrosion (OECD TG 410). Paris: Organisation for Economic Co-operation and Development (OECD); 2015.
  • Zainal Z, Ong A, May CY, et al. Acute and subchronic oral toxicity of oil palm puree in sprague-dawley rats. IJERPH 2020;17:3404.
  • Jeon WY, Seo CS, Ha H, et al. Subchronic toxicological evaluation of Bojungikki-tang water extract: 13-week oral repeated-dose toxicity study in Crl:CD (SD) rats. J Ethnopharmacol 2020;252:112551.
  • OECD. OECD guideline for acute dermal irritation/corrosion (OECD TG 404). Paris: Organisation for Economic Co-operation and Development (OECD); 2015.
  • Ocampo S, Iris B, Sanchez SJL, et al. Evaluation of the toxicity and pathogenicity of biocontrol agents in murine models, chicken embryos and dermal irritation in rabbits. Toxicol Res 2017;6:188–198.
  • Dutok CMS, Azalea BRC, Elizabeth RL, et al. Acute toxicity and dermal and eye irritation of the aqueous and hydroalcoholic extracts of the seeds of "Zapote" Pouteria mammosa (L.) Cronquist. Sci World J 2015;2015:642906.
  • OECD. OECD guideline for acute dermal irritation/corrosion (OECD TG 406). Paris: Organisation for Economic Co-operation and Development (OECD); 2015.
  • Li X, He Z, Ding WF, et al. Periplaneta americana assessment of dermal safety of oil extracted fromml: acute dermal toxicity, irritation, and sensitization. Cutan Ocul Toxicol 2020;39:193–199.
  • Han SM, Lee KG, Park KK, et al. Skin sensitization study of bee venom (Apis mellifera L.) in guinea pigs. Toxicol Res 2013;28:1–4.
  • Maeda Y, Takeyoshi M. Proposal of GHS sub-categorization criteria for LLNA: BrdU-ELISA (OECD TG442B). Regul Toxicol Pharmacol 2019;107:104409.
  • Zhao LP, Chen YM, Chen YJ, et al. Effects of pH on protein components of extracted oil bodies from diverse plant seeds and endogenous protease-induced oleosin hydrolysis. Food Chem 2016;200:125–133.
  • Ling H. Oleosin fusion expression systems for the production of recombinant proteins. Biologia 2007;62:119–123.
  • Montesinos L, Bundó M, Izquierdo E, et al. Production of biologically active cecropin A peptide in rice seed oil bodies. PLOS One 2016;11:1–18.
  • Giddings G. Transgenic plants as factories for biopharmaceuticals. Nat Biotechnol 2000;18:1151.
  • Moloney MM, Rooijen GV, inventor; SemBioSys Genetics Ins., assignee. Preparation of heterologous proteins on oil bodies. United States patent US 6,753,167 B2. 2004 Jun 22.
  • Qiang WD, Zhou TT, Lan XX, et al. A new nanoscale transdermal drug delivery systemml: oil body-linked oleosin-hEGF improves skin regeneraiton to accelerate wound healing. J Nanobiotechnol 2018;16:62.
  • Kapchie VN, Wei D, Hauck C, et al. Enzyme-assisted aqueous extraction of oleosomes from soybeans (Glycine max). Agric Food Chem 2008;56:1766–1771.
  • Idogawa S, Abe N, Abe K, et al. Effect of oleosins on the stability of oil bodies in soymilk. FSTR 2018;24:677–685.
  • Dave AC, Ye A, Singh H. Structural and interfacial characteristics of oil bodies in coconuts (Cocos nucifera L.). Food Chem 2019;276:129–139.
  • Nikiforidis CV, Kiosseoglou V. Aqueous extraction of oil bodies from Maize Germ (Zea mays) and characterization of the resulting natural oil-in-water emulsion. Agric Food Chem 2009;57:5591–5596.
  • Zielbauer BI, Jackson AJ, Maurer S, et al. Soybean oleosomes studied by small angle neutron scattering (SANS). J Colloid Interface Sci 2018;529:197–204.
  • Wang FL, Zheng T, Hu ZH, et al. Overexpression of miR319a altered oil body morphogenesis and lipid content in Arabidopsis seeds. Plant Mol Biol Rep 2020;38:531–537.
  • Zhu DS, Shen YS, Wei LW, et al. Effect of particle size on the stability and flavor of cloudy apple juice. Food Chem 2020;328:126967.
  • Wu JH, Liu W, Xue CB, et al. Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure. Toxicol Lett 2009;191:1–8.
  • Alikhan FS, Maibach H. Topical absorption and systemic toxicity. Cutan Ocul Toxicol 2011;30:175–186.
  • Wang JZ, Li Z, Sun FF, et al. Evaluation of dermal irritation and skin sensitization due to vitacoxib. Toxicology Rep 2017;4:287–290.
  • Bakar NZA, Othman H, Rajab NF, et al. Primary skin irritation and dermal sensitization assay: in vivo evaluation of the essential oil from Piper sarmentosum Roxb. Phcog Mag 2019;15:S352–S358.
  • Giddings G. Transgenic plants as protein factories. Curr Opin Biotechnol 2001;12:450–454.

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