388
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Simultaneous analysis of mycotoxins in corn flour using LC/MS-MS combined with a modified QuEChERS procedure

, , , & ORCID Icon
Pages 187-195 | Received 12 Mar 2017, Accepted 09 Jul 2017, Published online: 31 Jul 2017

References

  • Åberg, A.T., et al., 2013. Development and in-house validation of an LC-MS/MS method for the quantification of the mycotoxins deoxynivalenol, zearalenone, T-2 and HT-2 toxin, ochratoxin A and fumonisin B1 and B2 in vegetable animal feed. Food additives & contaminants: part A, chemistry, analysis, control, exposure & risk, 30 (3), 541–549.
  • Almeida, I., et al., 2001. Co-occurrence of mycotoxins in swine feed produced in Portugal. Mycotoxin research, 27, 177–181.
  • Anastassiades, M., et al., 2003. Fast and easy multi residue method employing acetonitrile extraction/partitioning and dispersive solid-phase extraction for the determination of pesticide residues in produce. Journal of AOAC international, 86 (2), 412–431.
  • Beltran, E., et al., 2009. Determination of mycotoxins in different food commodities by ultra-high-pressure liquid chromatography coupled to triple quadrupole mass spectrometry. Rapid communications in mass spectrometry, 23, 1801–1809.
  • Berthiller, F., et al., 2005. Rapid simultaneous determination of major type A- and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography-tandem mass spectrometry. Journal of chromatography A, 1062, 209–216.
  • Bhat, R., Rai, R.V., and Karim, A.A., 2010. Mycotoxins in food and feed: present status and future concerns. Comprehensive reviews in food science and food safety, 9, 57–81.
  • Boevre, M.D., et al., 2013. Human exposure to mycotoxins and their masked forms through cereal-based foods in Belgium. Toxicology letters, 26, 218 (3), 281–292.
  • Blandino, M., et al., 2015. Role of the European corn borer (Ostrinia nubilalis) on contamination of maize with 13 Fusarium mycotoxins. Food additives & contaminants: part A, chemistry, analysis, control, exposure & risk, 32 (4), 533–543.
  • Burlakoti, R.R., et al., 2017. Comparative population structure and trichothecene mycotoxin profiling of Fusarium graminearum from corn and Wheat in Ontario, Central Canada. Plant pathology, 66, 14–27.
  • Campagnollo, F.B., et al., 2016. The occurrence and effect of unit operations for dairy products processing on the fate of aflatoxin M1: A review. Food control, 68, 310–329.
  • Chavez-Eng, C.M., Constanzer, M., and Matuzewski, B.K., 2002. High-performance liquid chromatographic-tandem mass spectrometric evaluation and determination of stable isotope labeled analogs of rofecoxib in human plasma samples from oral bioavailability studies. Journal of chromatography. B, analytical technologies in the biomedical and life sciences, 767, 117–129.
  • Chen, Y., et al., 2016. Development and optimization of a multiplex lateral flow immunoassay for the simultaneous determination of three mycotoxins in corn, rice and peanut. Food chemistry, 213, 478–484.
  • Commission Regulation (EC) No 1881/2006. (2006). Setting maximum levels for certain contaminants in foodstuffs.
  • Copetti, M.V., et al., 2012. Co-occurrence of ochratoxin A and aflatoxins in chocolate marketed in Brazil. Food control, 26, 36–41.
  • Fabregat-Cabello, N., et al., 2016. Comparison of approaches to deal with matrix effects in LC-MS/MS based determinations of mycotoxins in food and feed. World mycotoxin journal, 9(2), 149–161.
  • Furey, A., et al., 2013. Ion suppression; a critical review on causes, evaluation, prevention and applications. Talanta, 115, 104–122.
  • Guan, S.H., et al., 2011. Occurrence of mycotoxins in feeds and feed ingredients in China. Journal of food, agriculture and environment, 9 (2), 163–167.
  • Hadiani, M.R., et al., 2003. Survey of the natural occurrence of zearalenone in maize from northern Iran by thin-layer chromatography densitometry. Food additives and contaminants, 20, 380–385.
  • Hewavitharana, A.K., 2011. Matrix matching in liquid chromatography – mass spectrometry with stable isotope labeled internal standards – is it necessary? Journal of chromatography A, 1218, 359–361.
  • Ibáñez-Vea, M., et al., 2012. Co-occurrence of aflatoxins, ochratoxin A and zearalenone in barley from a northern region of Spain. Food Chemistry, 132, 35–42.
  • ISIRI 2002. Maximum tolerated limits of mycotoxins in foods and feeds. National Standard No.5925 Institute of Standard and Industrial Research of Iran.
  • Karami-Osboo, R., et al., 2012. Aflatoxin B1 in maize harvested over 3 years in Iran. Short communication food control, 23, 271–274.
  • Krska, R., Baumgartner, S., and Josephs, R., 2001. The state-of-the-art in the analysis of type-A and -B trichothecene mycotoxins in cereals. Fresenius’ journal of analytical chemistry, 1 371 (3), 285–299.
  • Lattanzio, V.M.T., et al., 2014. Improved method for the simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in cereals and derived products by liquid chromatography–tandem mass spectrometry after multi-toxin immunoaffinity clean up. Journal of chromatography A, 1354, 139–143.
  • Mahmoudi, R., et al., 2013. Total aflatoxin contamination of maize produced in different regions of Qazvin-Iran. International food research journal, 20 (5), 2901–2904.
  • Maine, J.J. and Boyles, J.G., 2015. Bats initiate vital agroecological interactions in corn. Proceedings of the national academy of sciences of the United States of America Sci, 112 (40), 12438–12443.
  • Mitchell, N.J., et al., 2016. Potential economic losses to the US corn industry from aflatoxin contamination. Food additives & contaminants. Part A, chemistry, analysis, control, exposure & risk assessment, 33 (3), 540–550.
  • Monbaliu, S., et al., 2010. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS Method. Journal of agricultural and food chemistry, 58, 66–71.
  • Njobeh, P.B., et al., 2012. Estimation of multi-mycotoxin contamination in South African compound feeds. Toxins 4, 836–848.
  • Rashedi, M., et al., 2012. Zearalenone contamination in barley, corn, silage and wheat bran. Toxicology and industrial health, 28 (9), 779–782.
  • Rastegar, H., et al., 2016. Removal of aflatoxin B1 by roasting with lemon juice and/or citric acid in contaminated pistachio nuts. Food control, 71, 279–284.
  • Ren, Y., et al., 2007. Simultaneous determination of multicomponent mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry. Journal of chromatogrhy A, 1143, 48–64.
  • Richard, J.L., 2007. Some major mycotoxins and their mycotoxicoses-an overview. International journal of food microbiology, 119, 3–10.
  • Robens, J. and Cardwell, K., 2003. The costs of mycotoxin management to the USA: management of aflatoxins in the United States. Journal of toxicology: toxin rev, 22 (2-3), 139–152.
  • Scussel, V.M., et al., 2014. Fumonisins in corn (Zea mays L.) from Southern Brazil. Food additives & contaminants: Part B, 7 (2), 151–155.
  • Shimshoni, J.A., et al., 2013. Mycotoxins in corn and wheat silage in Israel. Food additives & contaminants. Part A, chemistry, analysis, control, exposure & risk assessment, 30 (9), 1614–1625.
  • Spanjer, M.C., Rensen, P.M., and Scholten, J.M., 2008. LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs. Food additives & contaminants. Part A, chemistry, analysis, control, exposure & risk assessment, 25, 472–489.
  • Streit, E., et al., 2012. Current situation of mycotoxin contamination and co-occurrence in animal feed-focus on Europe. Toxins, 4, 788–809.
  • Sulyok, M., et al., 2006. Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize. Rapid communications in mass spectrometry: Rcm, 20, 2649–2659.
  • Tamuura, M., Uyama, A., and Mochizuki, N., 2011. Development of a multi-mycotoxin analysis in beer-based drinks by a modified QuEChERs method and ultra-high-performance liquid chromatography coupled with tandem mass spectrometry. Analytical sciences, 27, 629–634.
  • Tanaka, H., et al., 2006. Development of a liquid chromatography/time-of-flight mass spectrometric method for the simultaneous determination of trichothecenes, zearalenone and aflatoxins in foodstuffs. Rapid communications in mass spectrometry, 20, 1422–1428.
  • Tansakul, N., et al., 2013. Co-occurrence of five Fusarium toxins in corn-dried distiller’s grains with solubles in Thailand and comparison of ELISA and LC-MS/MS for fumonisin analysis. Mycotoxin research, 29 (4), 255–260.
  • Trufelli, H., et al., 2011. An overview of matrix effects in liquid chromatography-mass spectrometry. Mass spectrometry reviews, 30, 491–509.
  • Vargas, E.A., et al., 2001. Co-occurrence of aflatoxins B1, B2, G1, G2, zearalenone and fumonisin B1 in Brazilian corn. Food additives and contaminants, 18, 981–986.
  • Warth, B., et al., 2012. Quantitation of mycotoxins in food and feed from Burkina Faso and Mozambique using a modern LC-MS/MS multitoxin method. Journal of Agricultural and Food Chemistry, 60, 9352–9363.
  • World Health Organization (WHO), 1998. Safety evaluation of certain food additives and contaminants. Series No. 40. Food Additives. Geneva: WHO, 359–469.
  • World Health Organization (WHO), 2002. WHO global strategy for food safety: Safer food for better health. Available from: www.who.int/fsf.
  • Yazdanpanah, H., 2006. Mycotoxin contamination of foodstuffs and feedstuffs in Iran. Iranian journal of pharmaceutical research, 1, 9–16.
  • Yazdanpanah, H., et al., 2001. Natural occurrence of aflatoxins and ochratoxin A in corn and barley from Mazandaran and Golestan in north provinces of I.R. Iran. Mycotoxin research, 17, 21–30.
  • Yazdanpanaha, H., et al., 2014. Occurrence of deoxynivalenol in foods for human consumption from Tehran, Iran. Iranian journal of pharmaceutical research, 13, 87–92.
  • Yazdanpanaha, H., et al., 2012. Exposure assessment of the Tehran population (Iran) to zearalenone mycotoxin. Iranian journal of pharmaceutical research, 11 (1), 251–256.
  • Zhang, J.M., Wu, Y.L., and Lu, Y.B., 2013. Simultaneous determination of carbamate insecticides and mycotoxins in cereals by reversed phase liquid chromatography tandem mass spectrometry using a quick, easy, cheap, effective, rugged and safe extraction procedure. Journal of Chromatography, B915–916, 13–20.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.