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Epigenetics Volume 17, 2022 - Issue 13
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Research Paper

The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

Sarah Holmes Watkinsa MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8034-8095View further author information
ORCID Icon,
Karen Hob Bristol Bioresource Laboratories, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
,
Christian Testac Department of Social and Behavioral Sciences, Harvard T H Chan School of Public Health, Harvard University, Boston, MA, USAView further author information
,
Louise Falkd Integrative Cancer Epidemiology Programme (ICEP), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
,
Patrice Soulee Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USAView further author information
,
Linda V. Nguyenf Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USAView further author information
,
Sophie FitzGibbonb Bristol Bioresource Laboratories, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
,
Catherine Slackb Bristol Bioresource Laboratories, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
,
Jarvis T. Chenc Department of Social and Behavioral Sciences, Harvard T H Chan School of Public Health, Harvard University, Boston, MA, USAView further author information
,
George Davey Smitha MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
,
Immaculata De Vivoe Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA;f Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USAView further author information
,
Andrew J. Simpking School of Medicine, National University of Ireland Galway, Galway, IrelandView further author information
,
Kate Tillinga MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
,
Pamela D. Watermanc Department of Social and Behavioral Sciences, Harvard T H Chan School of Public Health, Harvard University, Boston, MA, USAView further author information
,
Nancy Kriegerc Department of Social and Behavioral Sciences, Harvard T H Chan School of Public Health, Harvard University, Boston, MA, USAView further author information
,
Matthew Sudermana MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
&
Caroline Reltona MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKView further author information
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Pages 2366-2376 | Received 08 Feb 2022, Accepted 05 Sep 2022, Published online: 14 Oct 2022

References

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  • Christiansen SN, Andersen JD, Kampmann ML, et al. Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts. Epigenetics. 2022;1–10. DOI:10.1080/15592294.2022.2051861
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