References
- Phelan S, Jelalian E, Coustan D, et al. Protocol for a randomized controlled trial of pre-pregnancy lifestyle intervention to reduce recurrence of gestational diabetes: gestational diabetes prevention/Prevención de la diabetes gestacional. Trials [Internet]. 2021 Dec 1;22(1). [cited 2022 Feb 2]. Available from: /pmc/articles/PMC8024941/
- Lesseur C, Chen J. Adverse maternal metabolic intrauterine environment and placental epigenetics: implications for fetal metabolic programming. Curr Environ Heal Reports. 2018 Dec 1;5(4):531–12.
- McIntyre HD, Catalano P, Zhang C, et al. Gestational diabetes mellitus. Nat Rev Dis Prim 2019 51 [Internet]. 2019 Jul 11; 5(1):1–19. [cited 2022 Feb 3]. Available from: https://www.nature.com/articles/s41572-019-0098-8
- Mack LR, Tomich PG Gestational Diabetes: Diagnosis, Classification, and Clinical Care [Internet]. Obstet Gynecology Clin North Am WB Saunders. 2017;44:207–217. [cited 2020 Sep 28]. Available from: https://pubmed.ncbi.nlm.nih.gov/28499531/
- Eades CE, Cameron DM, Evans JMM. Prevalence of gestational diabetes mellitus in Europe: a meta-analysis. Diabet Res Clin Pract. 2017 Jul 1;129:173–181.
- Xiong X, Saunders LD, Wang FL, et al. Gestational diabetes mellitus: prevalence, risk factors, maternal and infant outcomes. Int J Gynaecol Obstet [Internet]. 2001;75(3):221–228. [cited 2022 Jul 29]. Available from: https://pubmed.ncbi.nlm.nih.gov/11728481/
- Fakhrul-Alam M, Sharmin-Jahan MH, Nusrat-Sultana MZ, et al. Insulin secretory defect may be the major determinant of GDM in lean mothers. J Clin Transl Endocrinol [Internet]. 2020 Jun 1;20:100226. [cited 2022 Jul 28]. Available from: /pmc/articles/PMC7199011/
- Haertle L, El Hajj N, Dittrich M, et al. Epigenetic signatures of gestational diabetes mellitus on cord blood methylation. Clin Epigenetics. 2017 Mar 27;9:2–12.
- Yang IV, Zhang W, EJ D, et al. Epigenetic marks of in utero exposure to gestational diabetes and childhood adiposity outcomes: the EPOCH study. Diabet Med [Internet]. 2018 May 1;35(5):612–620. [cited 2021 Sep 22]. Available from: https://pubmed.ncbi.nlm.nih.gov/29461653/
- Dias S, Adam S, Rheeder P, et al. Altered genome-wide DNA methylation in peripheral blood of South African women with gestational diabetes mellitus. Int J Mol Sci [Internet]. 2019 Nov 20;20(23):5828. [cited 2020 Apr 20]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31757015
- Wu L, Cui L, Tam WH, et al. Genetic variants associated with gestational diabetes mellitus: a meta-analysis and subgroup analysis. Sci Rep [Internet]. 2016 Jul 29;6. [cited 2022 Feb 3]. Available from: https://pubmed.ncbi.nlm.nih.gov/27468700/
- Moore LD, Le T, Fan G DNA methylation and its basic function. Neuropsychopharmacology [Internet]. 2013 Jan;38(1):23–38. [cited 2022 Jul 28]. Available from: https://pubmed.ncbi.nlm.nih.gov/22781841/10.1038/npp.2012.112
- Dias S, Pheiffer C, Abrahams Y, et al. Molecular biomarkers for gestational diabetes mellitus. Int J Mol Sci. 2018 Oct 1;19:2926–2899.
- Valencia-Ortega J, Saucedo R, Sánchez-Rodríguez MA, et al. Epigenetic alterations related to gestational diabetes mellitus. Int J Mol Sci [Internet]. 2021 Aug 31;22(17):9462. [cited 2021 Sep 22]. Available from: https://www.mdpi.com/1422-0067/22/17/9462
- Canouil M, Khamis A, Keikkala E, et al. Epigenome-wide association study reveals methylation loci associated with offspring gestational diabetes mellitus exposure and maternal methylome. Diabetes Care [Internet]. 2021 Sep 1;44(9):1992–1999. [cited 2023 Mar 29]. Available from: https://pubmed.ncbi.nlm.nih.gov/34116986/
- Wu P, Farrell WE, Haworth KE, et al. Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies. Epigenetics [Internet]. 2018 Feb 1;13(2):122. [cited 2021 Oct 8]; Available from: /pmc/articles/PMC5873366/
- Ballesteros M, Gil-Lluís P, Ejarque M, et al. DNA methylation in gestational diabetes and its predictive value for postpartum glucose disturbances. J Clin Endocrinol Metab [Internet]. 2022 Aug 2. [cited 2022 Aug 9]. Available from: https://pubmed.ncbi.nlm.nih.gov/35914803/
- Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. National Diabetes Data Group Diabetes. 1979 Dec;28(12):1039–1057.
- Elsayed NA, Aleppo G, Aroda VR, et al. 15. Management of diabetes in pregnancy: standards of care in diabetes—2023. Diabetes Care [Internet]. 2023 Jan 1;46(Supplement_1):S254–66. [cited 2023 Mar 29]. Available from: https://diabetesjournals.org/care/article/46/Supplement_1/S254/148052/15-Management-of-Diabetes-in-Pregnancy-Standards
- Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia [Internet]. 1985 Jul;28(7):412–419. [cited 2023 Mar 29]. Available from: https://link.springer.com/article/10.1007/BF00280883
- Morris TJ, Butcher LM, Feber A, et al. ChAMP: 450k chip analysis methylation pipeline. Bioinformatics [Internet]. 2014 Feb 1;30(3):428–430. [cited 2022 Jun 13]. Available from: https://academic.oup.com/bioinformatics/article/30/3/428/228299
- Zhou W, Laird PW, Shen H Comprehensive characterization, annotation and innovative use of infinium DNA methylation BeadChip probes. Nucleic Acids Res [Internet]. 2017 Feb 28;45(4):e22. [cited 2022 Jun 13]. Available from: https://academic.oup.com/nar/article/45/4/e22/2290930
- Weng X, Liu F, Zhang H, et al. Genome-wide DNA methylation profiling in infants born to gestational diabetes mellitus. Diabet Res Clin Pract. 2018 Aug 1;142:10–18.
- Houseman EA, Accomando WP, Koestler DC, et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinf [Internet]. 2012 May 8;13(1):1–16. [cited 2022 Jun 13]. Available from: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-13-86
- Alptekin H, Çizmecioäÿlu A, Işik H, et al. Predicting gestational diabetes mellitus during the first trimester using anthropometric measurements and HOMA-IR. J Endocrinol Invest [Internet]. 2016 May 1;39(5):577–583. [cited 2023 Mar 29]. Available from: https://pubmed.ncbi.nlm.nih.gov/26754418/
- Samra NA, Jelinek HF, Alsafar H, et al. Genomics and epigenomics of gestational diabetes mellitus: understanding the molecular pathways of the disease pathogenesis. Int J Mol Sci [Internet]. 2022 Apr 1;23(7). [cited 2022 Aug 8]. Available from: https://pubmed.ncbi.nlm.nih.gov/35408874/
- Mollet IG, Malm HA, Wendt A, et al. Integrator of stress responses calmodulin binding transcription activator 1 (Camta1) regulates miR-212/miR-132 expression and insulin secretion. J Biol Chem [Internet]. 2016 Aug 26;291(35):18440–18452. [cited 2022 Aug 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/27402838/
- Saltiel AR, Kahn CR Insulin signalling and the regulation of glucose and lipid metabolism. Nature [Internet]. 2001 Dec 13;414(6865):799–806. [cited 2023 Mar 29]. Available from: https://pubmed.ncbi.nlm.nih.gov/11742412/
- Dias S, Adam S, Rheeder P, et al. Altered genome-wide DNA methylation in peripheral blood of South African women with gestational diabetes mellitus. Int J Mol Sci [Internet]. 2019 Dec 1;20(23). [cited 2021 Sep 22]. Available from: https://pubmed.ncbi.nlm.nih.gov/31757015/
- Wei FJ, Cai CY, Yu P, et al. Quantitative candidate gene association studies of metabolic traits in Han Chinese type 2 diabetes patients. Genet Mol Res [Internet]. 2015 Nov 30;14(4):15471–15481. [cited 2022 Aug 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/26634513/
- Mohamed SA, Fernadez-Tajes J, Franks PW, et al. GWAS in people of Middle Eastern descent reveals a locus protective of kidney function-a cross-sectional study. BMC Med [Internet]. 2022 Dec 1;20(1). [cited 2022 Aug 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/35227251/
- Cauchi S, Proença C, Choquet H, et al. Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study. J Mol Med (Berl) [Internet]. 2008 Mar;86(3):341–348. [cited 2022 Aug 10]. Available from: https://pubmed.ncbi.nlm.nih.gov/18210030/
- Ellerbrock J, Spaanderman B, Drongelen JV, et al. Role of beta cell function and insulin resistance in the development of gestational diabetes mellitus. Nutrients [Internet]. 2022 Jun 13;14(12):2444. [cited 2022 Aug 9]. Available from: /pmc/articles/PMC9231208/.
- Zhang NJ, Tao MF, Li HP, et al. The relationship between patterns of insulin secretion and risks of gestational diabetes mellitus. Int J Gynaecol Obstet [Internet]. 2020 Sep 1;150(3):318–323. [cited 2022 Aug 9]. Available from: https://pubmed.ncbi.nlm.nih.gov/32415984/
- Doria A, Patti ME, Kahn CR The emerging genetic architecture of type 2 diabetes. Cell Metab [Internet]. 2008 Sep 3;8(3):186–200. [cited 2022 Aug 10]; Available from: http://www.cell.com/article/S1550413108002477/fulltext
- Florez JC The genetics of type 2 diabetes: a realistic appraisal in 2008. J Clin Endocrinol Metab [Internet]. 2008 Dec 1;93(12):4633–4642. [cited 2022 Aug 10]. Available from: https://academic.oup.com/jcem/article/93/12/4633/2627272
- Staiger H, Machicao F, Fritsche A, et al. Pathomechanisms of type 2 diabetes genes. Endocr Rev [Internet]. 2009 Oct 1;30(6):557–585. [cited 2022 Aug 10]. Available from: https://academic.oup.com/edrv/article/30/6/557/2355053
- Cho H, Mu J, Kim JK, et al. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science [Internet]. 2001 Jun 1;292(5522):1728–1731. [cited 2023 Mar 27]. Available from: https://pubmed.ncbi.nlm.nih.gov/11387480/
- Manning A, Highland HM, Gasser J, et al. A low-frequency inactivating AKT2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk. Diabetes [Internet]. 2017 Jul 1;66(7):2019–2032. [cited 2023 Mar 27]. Available from: https://pubmed.ncbi.nlm.nih.gov/28341696/
- Latva-Rasku A, Honka MJ, Stancáková A, et al. A partial loss-of-function variant in AKT2 is associated with reduced insulin-mediated glucose uptake in multiple insulin-sensitive tissues: a genotype-based callback positron emission tomography study. Diabetes [Internet]. 2018 Feb 1;67(2):334–342. [cited 2023 Mar 27]. Available from: https://diabetesjournals.org/diabetes/article/67/2/334/15949/A-Partial-Loss-of-Function-Variant-in-AKT2-Is
- Yang X, Han H, DeCarvalho DD, et al. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell [Internet]. 2014 Oct 13;26(4):577–590. [cited 2023 Mar 27]. Available from: https://pubmed.ncbi.nlm.nih.gov/25263941/
- Alejandro EU, Bozadjieva N, Blandino-Rosano M, et al. Overexpression of kinase-dead mTOR impairs glucose homeostasis by regulating insulin secretion and not β-cell mass. Diabetes [Internet]. 2017 Aug 1;66(8):2150–2162. [cited 2023 Mar 27]. Available from: https://pubmed.ncbi.nlm.nih.gov/28546423/
- Leprivier G, Rotblat B How does mTOR sense glucose starvation? AMPK is the usual suspect. Cell Death Discov [Internet]. 2020 Dec 1;6(1). [cited 2023 Mar 27]. Available from: https://pubmed.ncbi.nlm.nih.gov/32351714/
- Ganbold M, Ferdousi F, Arimura T, et al. New amphiphilic squalene derivative improves metabolism of adipocytes differentiated from diabetic adipose-derived stem cells and prevents excessive lipogenesis. Front Cell Dev Biol [Internet]. 2020 Nov 4;8. [cited 2022 Aug 11]. Available from: https://pubmed.ncbi.nlm.nih.gov/33251210/
- Virginia DM, Dwiprahasto I, Wahyuningsih MSH, et al. The effect of PRKAA2 variation on type 2 diabetes mellitus in the Asian population: a systematic review and meta-analysis. Malays J Med Sci [Internet]. 2022 Jun 28;29(3):5–16. [cited 2022 Aug 11]. Available from: https://pubmed.ncbi.nlm.nih.gov/35846493/
- Saha AK, Xu XJ, Lawson E, et al. Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. Diabetes [Internet]. 2010 Oct;59(10):2426–2434. [cited 2023 Mar 27]. Available from: https://pubmed.ncbi.nlm.nih.gov/20682696/
- Wang HL, Wang L, Zhao CY, et al. Role of TGF-Beta signaling in beta cell proliferation and function in diabetes. Biomolecules [Internet]. 2022 Mar 1;12(3):373. [cited 2022 Sep 26]. Available from: /pmc/articles/PMC8945211/
- Kobayashi H, Looker HC, Satake E, et al. Neuroblastoma suppressor of tumorigenicity 1 is a circulating protein associated with progression to end-stage kidney disease in diabetes. Sci Transl Med [Internet]. 2022 Aug 10;14(657):eabj2109. [cited 2022 Sep 26]. Available from: https://www.science.org/doi/10.1126/scitranslmed.abj2109