THB1 regulates nitrate reductase activity and THB1 and THB2 transcription differentially respond to NO and the nitrate/ammonium balance in Chlamydomonas

References

• Rosales EP, Iannone MF, Groppa MD, Benavides MP. Nitric oxide inhibits nitrate reductase activity in wheat leaves. Plant Physiol Biochem 2011; 49:124-30; PMID:21093280; http://dx.doi.org/10.1016/j.plaphy.2010.10.009
   Google Scholar
• Jin CW, Du ST, Zhang YS, Lin XY, Tang CX. Differential regulatory role of nitric oxide in mediating nitrate reductase activity in roots of tomato (Solanum lycocarpum). Ann Bot 2009; 104:9-17; PMID:19376780; http://dx.doi.org/10.1093/aob/mcp087
   Google Scholar
• Franco AR, Cárdenas J, Fernandez E. Involvement of Reversible Inactivation in the Regulation of Nitrate Reductase Enzyme Levels in Chlamydomonas reinhardtii. Plant Physiol 1987; 84:665-9; PMID:16665499; http://dx.doi.org/10.1104/pp.84.3.665
   Google Scholar
• Sanz-Luque E, Ocana-Calahorro F, Llamas A, Galvan A, Fernandez E. Nitric oxide controls nitrate and ammonium assimilation in Chlamydomonas reinhardtii. J Exp Bot 2013; 64:3373-83; PMID:23918969; http://dx.doi.org/10.1093/jxb/ert175
   Google Scholar
• Smagghe BJ, Trent JT, Hargrove MS. NO Dioxygenase Activity in Hemoglobins Is Ubiquitous In Vitro, but Limited by Reduction In Vivo. PLoS ONE 2008; 3:e2039; http://dx.doi.org/10.1371/journal.pone.0002039
   Google Scholar
• Perazzolli M, Dominici P, Romero-Puertas MC, Zago E, Zeier J, Sonoda M, Lamb C, Delledonne M. Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity. Plant Cell 2004; 16:2785-94; PMID:15367716; http://dx.doi.org/10.1105/tpc.104.025379
   Google Scholar
• Sainz M, Pérez-Rontomé C, Ramos J, Mulet JM, James EK, Bhattacharjee U, Petrich JW, Becana M. Plant hemoglobins may be maintained in functional form by reduced flavins in the nuclei, and confer differential tolerance to nitro-oxidative stress. Plant J 2013; 76:875-87; PMID:24118423; http://dx.doi.org/10.1111/tpj.12340
   Google Scholar
• Bonamore A, Boffi A. Flavohemoglobin: Structure and reactivity. IUBMB Life 2007; 60:19-28; http://dx.doi.org/10.1002/iub.9
   Google Scholar
• Ouellet H, Ouellet Y, Richard C, Labarre M, Wittenberg B, Wittenberg J, Guertin M. Truncated hemoglobin HbN protects Mycobacterium bovis from nitric oxide. Proc Natl Acad Sci USA 2002; 99:5902-7; PMID:11959913; http://dx.doi.org/10.1073/pnas.092017799
   Google Scholar
• Singh S, Thakur N, Oliveira A, Petruk AA, Hade MD, Sethi D, Bidon-Chanal A, Martí MA, Datta H, Parkesh R, et al. Mechanistic Insight into the Enzymatic Reduction of Truncated Hemoglobin N of Mycobacterium tuberculosis: Role of the cd loop and pre-a motif in electron cycling. J Biol Chem 2014; 289:21573-83; PMID:24928505; http://dx.doi.org/10.1074/jbc.M114.578187
   Google Scholar
• Stewart JJ, Coyne KJ. Analysis of raphidophyte assimilatory nitrate reductase reveals unique domain architecture incorporating a 2/2 hemoglobin. Plant Mol Biol 2011; 77:565-75; PMID:22038092; http://dx.doi.org/10.1007/s11103-011-9831-8
   Google Scholar
• Trevisan S, Manoli A, Begheldo M, Nonis A, Enna M, Vaccaro S, Caporale G, Ruperti B, Quaggiotti S. Transcriptome analysis reveals coordinated spatiotemporal regulation of hemoglobin and nitrate reductase in response to nitrate in maize roots. New Phytol 2011; 192:338-52; PMID:21762167; http://dx.doi.org/10.1111/j.1469-8137.2011.03822.x
   Google Scholar
• Yamasaki H, Sakihama Y. Simultaneous production of nitric oxide and peroxynitrite by plant nitrate reductase: in vitro evidence for the NR-dependent formation of active nitrogen species. FEBS Lett 2000; 468:89-92; PMID:10683447; http://dx.doi.org/10.1016/S0014-5793(00)01203-5
   Google Scholar
• Sakihama Y, Nakamura S, Yamasaki H. Nitric oxide production mediated by nitrate reductase in the green alga Chlamydomonas reinhardtii: an alternative NO production pathway in photosynthetic organisms. Plant Cell Physiol 2002; 43:290-7; PMID:11917083; http://dx.doi.org/10.1093/pcp/pcf034
   Google Scholar
• Rockel P, Strube F, Rockel A, Wildt J, Kaiser WM. Regulation of nitric oxide (NO) production by plant nitrate reductase in vivo and in vitro. J Exp Bot 2002; 53:103-10; PMID:11741046; http://dx.doi.org/10.1093/jexbot/53.366.103
   Google Scholar
• Hemschemeier A, Düner M, Casero D, Merchant SS, Winkler M, Happe T. Hypoxic survival requires a 2-on-2 hemoglobin in a process involving nitric oxide. Proc Natl Acad Sci USA 2013; 110:10854-9; PMID:23754374; http://dx.doi.org/10.1073/pnas.1302592110
   Google Scholar
• de Montaigu A, Sanz-Luque E, Macias MI, Galvan A, Fernandez E. Transcriptional regulation of CDP1 and CYG56 is required for proper NH4+ sensing in Chlamydomonas. J Exp Bot 2011; 62:1425-37; PMID:21127023; http://dx.doi.org/10.1093/jxb/erq384
   Google Scholar
• de Montaigu A, Sanz-Luque E, Galvan A, Fernandez E. A soluble guanylate cyclase mediates negative signaling by ammonium on expression of nitrate reductase in Chlamydomonas. Plant Cell 2010; 22:1532-48; PMID:20442374; http://dx.doi.org/10.1105/tpc.108.062380
   Google Scholar
• Fernandez E, Cardenas J. Regulation of the nitrate-reducing system enzymes in wild-type and mutant strains of Chlamydomonas reinhardii. Molec Gen Genet 1982; 186:164-9; PMID:6810063; http://dx.doi.org/10.1007/BF00331846
   Google Scholar