172
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Reducing the severity of alcohol withdrawal with oral baclofen: a randomized controlled trial

, , , , , & show all
Pages 220-225 | Received 02 Feb 2018, Accepted 21 Jun 2018, Published online: 28 Sep 2018

References

  • Addolorato G, Caputo F, Capristo E, Janiri L, Bernardi M, Agabio R, Colombo G, Gessa GL, Gasbarrini G. 2002. Rapid suppression of alcohol withdrawal syndrome by baclofen. Am J Med. 112:226–229.
  • Addolorato G, Leggio L, Abenavoli L, Agabio R, Caputo F, Capristo E, Colombo G, Gessa GL, Gasbarrini G. 2006. Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam. Am J Med. 119:276.e13–276.
  • Addolorato G, Leggio L, Abenavoli L, DeLorenzi G, Parente E, Caputo F, Janiri L, Capristo E, Rapaccini GL, Gasbarinni G. 2003. Suppression of alcohol delrium tremens by Baclofen administration: a case report. Clin Neuropharmacol. 26:258–262.
  • Ameisen O. 2004 Mar-Apr. Complete and Prolonged Suppression of Symptoms and Consequences of Alcohol-Dependence using high-dose baclofen: a self-case report of a physician. Alcohol Alcohol. 40:147–150.
  • Bard MR, Goettler CE, Toschlog EA, Sagraves SG, Schenarts PJ, Newell MA, Fugate M, Rotondo MF. 2006. Alcohol withdrawal syndrome: Turning minor injuries into a major problem. J Trauma. 61:1441–1446.
  • Bucknam W. 2007. Suppression of symptoms of alcohol dependence and craving using high-dose Baclofen. Alcohol Alcohol. 42:158–160.
  • Garbutt J, Kampov-Polevoy A, Gallop R, Kalka-Juhl L, Flannery B. 2010. Efficacy and safety of Baclofen for alcohol dependence: a randomized, double blind, placebo-controlled Trial. Alcohol Clin Exp Res. 34:1849–1857.
  • Genther DJ, Gourin CG. 2012. The effect of alcohol abuse and alcohol withdrawal on short termoutcomes and cost of care after head and neck cancer surgery. Laryngoscope. 122:1739–1747.
  • Girish K, Vikram Reddy K, Pandit LV, Pundarikaksha HP, Vijendra R, Vasundara K, Manjunatha R, Moulya N, Shruthi R. 2016. A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome. Biomed J. 39:72–80.
  • Heydtmann M. 2011. Baclofen effect related to liver damage. Alcohol Clin Exp Res. 35:848.
  • Liu J, Wang LN. 2017. Baclofen for alcohol withdrawal. Cochrane Database Syst Rev. DOI:10.1002/14651858.CD008502.pub5
  • Lyon JE, Khan RA, Gessert CE, Larson PM, Renier CM. 2011. Treating alcohol withdrawal with oral baclofen: A randomized, double-blind, placebo-controlled trial. J Hosp Med. 6:469–479.
  • Neyman KM, Gourin CG, Terris DJ. 2005. Alcohol withdrawal prophylaxis in patients undergoing surgical treatment of head and neck squamous cell carcinoma. Laryngoscope. 115:786–790.
  • O'Connor PG, Schottenfeld RS. 1998. Patients with alcohol problems. N Engl J Med. 338:592–602.
  • Swift RM. 1999. Drug therapy for alcohol dependence. N Engl J Med. 340:1482–1490.
  • Westerink BH, Kwint HF, DeVries JB. 1996. The pharmacology of mesolimbic dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain. J Neurosci. 16:2605–2611.
  • Yoshida M, Yokoo H, Tanaka T, Emoto H, Tanaka M. 1994. Opposite changes in the mesolimbic dopamine metabolism in the nerve terminal and cell body sites induced by locally infused baclofen in the rat. Brain Research. 636:111–114.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.