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Hematology Volume 25, 2020 - Issue 1
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Research Article

Real-world analysis of treatment patterns and clinical outcomes in patients with newly diagnosed chronic lymphocytic leukemia from seven Latin American countries

Carlos Chiattonea Hematology and Oncology Discipline, Santa Casa Medical School, Sao Paulo, BrazilView further author information
,
David Gomez-Almaguerb Hematology Service, Hospital Universitario “Dr. José E. González”, Monterrey, MexicoORCID Iconhttps://orcid.org/0000-0002-0460-6427View further author information
ORCID Icon,
Carolina Pavlovskyc FUNDALEU Hospital and Clinical Research Centre, Buenos Aires, ArgentinaView further author information
,
Elena J. Tuna-Aguilard Hematology and Oncology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoView further author information
,
Ana L. Basquierae Hematology, Hospital Privado Centro Medico de Cordoba, Cordoba, ArgentinaView further author information
,
Luis Palmerf Complejo Medico de la PFA Churruca – Visca, ArgentinaView further author information
,
Danielle Leao Cordeiro de Fariasg Hospital das Clinicas da Universidade Federal de Goias, Goiânia, BrazilORCID Iconhttps://orcid.org/0000-0002-3140-2235View further author information
ORCID Icon,
Sergio Schusterschitz da Silva Araujoh Hospital das Clínicas - Universidade Federal de Minas Gerais, BrazilView further author information
,
Kenny Mauricio Galvez-Cardenasi Hospital Pablo Tobón Uribe, Medellin, ColombiaView further author information
,
Alvaro Gomez Diazj Hemato Oncologos S.A., Cali, ColombiaView further author information
,
Jennifer H. Link Janssen Scientific Affairs, LLC, Titusville, NJ, USAView further author information
,
Yen-wen Chenk Janssen Scientific Affairs, LLC, Titusville, NJ, USAView further author information
,
Gerardo Machnickil Janssen Cilag Farmaceutica SA, Buenos Aires, ArgentinaView further author information
,
Michelle Mahlerm Janssen Global Services, LLC, Raritan, NJ, USAView further author information
,
Lori Parisin Janssen Pharmaceutical Companies of Johnson and Johnson, Titusville, NJ, USAView further author information
&
Paula Barreyrol Janssen Cilag Farmaceutica SA, Buenos Aires, ArgentinaCorrespondence[email protected]
View further author information
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Pages 366-371 | Published online: 23 Oct 2020

References

  • Vidal L, Gurion R, Ram R, et al. Chlorambucil for the treatment of patients with chronic lymphocytic leukemia (CLL) - a systematic review and meta-analysis of randomized trials. Leuk Lymphoma. 2016;57:2047–2057.
  • Goede V, Fischer K, Busch R, et al. Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions. N Engl J Med. 2014;370:1101–1110.
  • Pulte D, Castro FA, Jansen L, et al. Trends in survival of chronic lymphocytic leukemia patients in Germany and the USA in the first decade of the twenty-first century. J Hematol Oncol. 2016;9:28.
  • Burger JA, Tedeschi A, Barr PM, et al. Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia. N Engl J Med. 2015;373:2425–2437.
  • Chiattone C, Gomez-Almaguer D, Pavlovsky C, et al. Results from hemato-oncology Latin America observational registry (HOLA) providing real world outcomes for the treatment of patients with CLL. Blood. 2016;128:5578.
  • Mato A, Nabhan C, Kay NE, et al. Real-world clinical experience in the Connect® chronic lymphocytic leukaemia registry: a prospective cohort study of 1494 patients across 199 US centres. Br J Haematol. 2016;175:892–903.
  • Goncalves MV, Rodrigues CA, Lorand Metze IGH, et al. Chronic lymphocytic leukemia in Brazil: a retrospective analysis of 1903 cases. Am J Hematol. 2017;92:E171–E173.
  • Eichhorst B, Robak T, Montserrat E, et al. Chronic lymphocytic leukaemia: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2015;26(Suppl. 5):v78–v84.
  • Owen C, Gerrie AS, Banerji V, et al. Canadian evidence-based guideline for the first-line treatment of chronic lymphocytic leukemia. Curr Oncol. 2018;25:e461–e474.
  • Schuh AH, Parry-Jones N, Appleby N, et al. Guideline for the treatment of chronic lymphocytic leukaemia: A British Society for Haematology Guideline. Br J Haematol. 2018;182:344–359.
  • Wierda WG, Zelenetz AD, Gordon LI, et al. NCCN guidelines insights: chronic lymphocytic leukemia/small lymphocytic lymphoma, Version 1.2017. J Natl Compr Canc Netw. 2017;15:293–311.
  • Ruiz R, Strasser-Weippl K, Touya D, et al. Improving access to high-cost cancer drugs in Latin America: much to be done. Cancer. 2017;123:1313–1323.
  • Guerrero C. Cancer preparedness in Latin America: the need to build on recent progress. In: Koehring M, editor. The Economist Intelligence Unit; 2019. p. 45.

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