Advanced search
Publication Cover
Hematology Volume 26, 2021 - Issue 1
Submit an article Journal homepage
1,828
Views
1
CrossRef citations to date
0
Altmetric
Articles

Analysis of the influencing factors related to liver and cardiac iron overload in MDS patients detected by MRI in the real world

Chao Xiaoa Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
,
Yao Zhangb Department of Hematology, Eastern Branch of the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-7010-1646
ORCID Icon,
Jun-gong Zhaoc Department of Radiology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
,
Lu-xi Songa Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
,
You-shan Zhaoa Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
,
Yan Jiaa Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
,
Juan Guoa Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
,
Shuang Hanb Department of Hematology, Eastern Branch of the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, People’s Republic of China
,
Zhao-wei Lib Department of Hematology, Eastern Branch of the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, People’s Republic of China
,
Cha Guob Department of Hematology, Eastern Branch of the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, People’s Republic of China
,
Xiao Lia Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of China
&
Chun-kang Changa Department of Hematology, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People’s Republic of ChinaCorrespondence[email protected] [email protected]
 show all
Pages 123-133 | Published online: 25 Jan 2021

References

  • Camaschella C, Nai A. Ineffective erythropoiesis and regulation of iron status in iron loading anaemias. Br J Hematol. 2016;172(4):512–523.
  • Gu S, Zhao Y, Guo J, et al. High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome. Tumor Biol. 2014;35:2211–2218.
  • Fragasso A, Ciancio A, Mannarella C, et al. Myocardial iron overload assessed by magnetic resonance imaging (MRI) T2* in multi-transfused patients with thalassemia and acquired anemias. Eur J Intern Med. 2011;22(1):62–65.
  • Armand P, Kim HT, Rhodes J, et al. Iron overload in patients with acute leukemia or MDS undergoing myeloablative stem cell transplantation. Biol Blood Marrow Transplant. 2011;17(6):852–860.
  • Abbass G, Farhan S, Nadeem MA, et al. Frequency of iron overload in patients of chronic hepatitis C undergoing therapy and treatment response in patients with iron overload. Pakistan J Med Health Sci. 2016;10(2):399–401.
  • Hematology Branch of the Chinese Medical Association. MDS diagnosis and treatment expert consensus 2012. Chin J Hematol. 2012;33:347–352.
  • Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391–2405.
  • Gattermann N, Rachmilewitz EA. Iron overload in MDS pathophysiology, diagnosis, and complications. Ann Hematol. 2011;90(1):1–10.
  • Malcovati L, Della Porta MG, Pascutto C, et al. Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: a basis for clinical decision making. J Clin Oncol. 2005;23:7594–7603.
  • Kountouras D, Tsagarakis NJ, Fatourou E, et al. Liver disease in adult transfusion-dependent beta-thalassaemic patients: investigating the role of iron overload and chronic HCV infection. Liver Int. 2013;33:420–427.
  • Abeid ZK, Al-Tu'ma FJ, Al-Naffi KO. Polymorphism of HFE gene in ischemic heart diseases and its relation with iron overload. Ijppr Human. 2017;8(3):31–41.
  • Angelucci E, Cianciulli P, Finelli C, et al. Unraveling the mechanisms behind iron overload and ineffective hematopoiesis in myelodysplastic syndromes. Leuk Res. 2017;62:108–115.
  • Cui R, Gale RP, Zhu G, et al. Serum iron metabolism and erythropoiesis in patients with myelodysplastic syndrome not receiving RBC transfusions. Leuk Res. 2014;38(5):545–550.
  • Kautz L, Jung G, Du X, et al. Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia. Blood. 2015;126(17):2031–2037.
  • Cancado R, Watman NP, Lobo C, et al. Assessment of liver and cardiac iron overload using MRI in patients with chronic anemias in Latin American countries: results from ASIMILA study. Hematology. 2018;23(9):676–682.
  • Noetzli LJ, Carson SM, Nord AS, et al. Longitudinal analysis of heart and liver iron in thalassemia major. Blood. 2008;112(7):2973–2978.
  • Zhang Y. Effect of iron chelation therapy on EPO-STAT5 signalling pathway and EPO resistance in iron overloaded low-risk myelodysplastic syndrome patients. Hematology. 2020;25(1):1–10.
  • Girellid D, Pasino M, Goodnough JB, et al. Reduced serum hepcidin levels in patients with chronic hepatitis C. J Hepatol. 2009;51(5):845–852.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.