Advanced search
Publication Cover
Hematology Volume 27, 2022 - Issue 1
Submit an article Journal homepage
1,620
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Molecular epidemiological investigation of abnormal hemoglobin in Shaokwan region, southern China

Hui Yanga Department of Laboratory Medicine, School of Medicine, Yangtze University, Jingzhou, People’s Republic of ChinaView further author information
,
Min Linb School of Food Engineering and Biotechnology, Hanshan Normal University, Chaozhou, People’s Republic of ChinaView further author information
,
Fen Linc Laboratory Medical Center, Chaozhou Central Hospital, Chaozhou, People’s Republic of ChinaView further author information
,
Zhan-Zhong Mad Laboratory Medical Center, Yuebei People’s Hospital Affiliated to Shantou Medical College, Shaoguan, People’s Republic of ChinaView further author information
,
Xiao-Fen Zhanc Laboratory Medical Center, Chaozhou Central Hospital, Chaozhou, People’s Republic of ChinaView further author information
&
Li-Ye Yange Precision Medical Center, People’s Hospital of Yangjiang, Yangjiang, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1581-9089View further author information
ORCID Icon
Pages 150-156 | Published online: 24 Jan 2022

References

  • Weatherall DJ, Clegg JB. Inherited haemoglobin disorders: an increasing global health problem. Bull World Health Organ. 2001;79(8):704–712.
  • Kohne E. Hemoglobinopathies: clinical manifestations, diagnosis, and treatment. Dtsch Arztebl Int. 2011;108(31-32):532–540.
  • Zeng YT, Huang SZ. Disorders of haemoglobin in China. J Med Genet. 1987;24:578–583.
  • Ren BZ, Liu Y. Disorders of haemoglobin in Guangdong province. part I a report on the investigation of abnormal haemoglobin among 83510 persons in some areas of Guangdong province (Mei-Zhou and Shao-Guan). Acta Jinan Univ. 1986;4:15–17. [In Chinese].
  • Handoo A, Sood SK. Laboratory diagnosis of hemoglobinpathies and thalassemia syndromes. In: A Sachdeva, VK Khama, SP Yadav, etal, editors. Hemoglobinopathies. New Delhi, Jaypee Brothers Medical Publishers; 2006. p. 110–114.
  • Lin M, Wang Q, Zheng L, et al. Prevalence and molecular characterization of abnormal hemoglobin in eastern Guangdong of southern China. Clin Genet. 2012;81(2):165–171.
  • Lin M, Zhu JJ, Wang Q, et al. Development and evaluation of a reverse dot blot assay for the simultaneous detection of common alpha and beta thalassemia in Chinese. Blood Cells Mol Dis. 2012;48(2):86–90.
  • Du RF. Population genetics of Chinese. Beijing: Science Publishing House; 2004, pp. 202-206. [In Chinese].
  • Qin LY. The incidence, distributing and genetic polymorphism of the abnormal hemoglobin in China. Bull Med Res. 2003;32:12–14. [In Chinese].
  • Lin M, Wen YF, Wu JR, et al. Hemoglobinopathy: molecular epidemiological characteristics and health effects on Hakka people in the Meizhou region, southern China. PLoS One. 2013;8(2):e55024.
  • Luo XL. The origin of hakka. Beijing: China Overseas Chinese Publishing Company; 1989. [In Chinese].
  • Zhong SH, Huang DQ. The spatial distribution and group characteristic of Chinese Hakkas. Guangxi Ethnic Studies. 2007;4:80–85. [In Chinese].
  • Wang WZ, Wang CY, Cheng YT, et al. Tracing the origins of Hakka and chaoshanese by mitochondrial DNA analysis. Am J Phys Anthropol. 2010;141(1):124–130.
  • Hu SP, Luan JA, Li B, et al. Genetic link between Chaoshan and other Chinese Han populations: evidence from HLA-A and HLA-B allele frequency distribution. Am J Phys Anthropol. 2007;132(1):140–150.
  • Qin LY. The incidence, distributing and genetic polymorphism of the abnormal hemoglobin in China minority. Bull Med Res. 2004;33:39–40. [In Chinese].
  • Lin M, Han ZJ, Wang Q, et al. Molecular epidemiological survey of Hemoglobinopathies in the wuxi region of Jiangsu province, eastern China. Hemoglobin. 2013;37(5):454–466.
  • Huang H, Xu L, Chen M, et al. Molecular characterization of thalassemia and hemoglobinopathy in southeastern China. Sci Rep. 2019;9(1):3493.
  • Xu A, Chen W, Xie W, et al. Hemoglobin variants in southern China: results obtained during the measurement of glycated hemoglobin in a large population. Clin Chem Lab Med. 2021;59(1):227–232.
  • Vella F, Wells RH, Ager JA, et al. A haemoglobinopathy involving haemoglobin H and a new (Q) haemoglobin. Br Med J. 1958;1(5073):752–755.
  • Singsanan S, Karnpean R, Fucharoen G, et al. Hemoglobin Q-Thailand related disorders: origin, molecular, hematological and diagnostic aspects. Blood Cells Mol Dis. 2010;45(3):210–214.
  • Seminar on digital development of Chinese Hakka cultural content. Guangzhou: South China University of Technology Press; 2018. [In Conference].
  • Zhong Z, Chen J, Guan Z, et al. [Phenotypic and genotypic analysis of 45 cases with Hemoglobin Q-Thailand]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2018;35(5):723–726. [In Chinese].
  • Zhang Q, Fan X, Wei Y, et al. Genetic analysis on Hb Q-Thailand in Nanning city of Guangxi. Lab Med Clinic. 2014;20:2803–2804, 2807. [In Chinese].
  • Huang C, Tang N, Lu BY, et al. Screening hemoglobin Q-Thailand combined alpha-thalassemia in Liuzhou region. Chin J Birth Health Heredity. 2017;25(11):26–27, 34. [In Chinese].

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.