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Hematology Volume 27, 2022 - Issue 1
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Research Article

The favorable prognostic value of the loss of sex chromosomes in patients with t(8;21) acute myeloid leukemia: an exploratory study

Lixia ZhuDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Rongrong ChenDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Xueying LiDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Mixue XieDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Xiudi YangDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Jianai SunDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Mingyu ZhuDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Xiaolong ZhengDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Li LiDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Jingjing ZhuDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
De ZhouDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
,
Wanzhuo XieDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
&
Xiujin YeDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence[email protected]
View further author information
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Pages 420-425 | Published online: 12 Apr 2022

References

  • Peterson LF, Boyapati A, Ahn EY, et al. Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts. Blood. 2007;110(3):799–805. doi:10.1182/blood-2006-11-019265.
  • Chen G, Zhou W, Gong D, et al. Loss of X chromosome predicts favorable prognosis in female patients with t(8;21) acute myeloid leukemia. Leuk Lymphoma. 2020;61(5):1168–1177. doi:10.1080/10428194.2019.1709836.
  • Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391–2405. doi:10.1182/blood-2016-03-643544.
  • Dohner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–447. doi:10.1182/blood-2016-08-733196.
  • Duployez N, Marceau-Renaut A, Boissel N, et al. Comprehensive mutational profiling of core binding factor acute myeloid leukemia. Blood. 2016;127(20):2451–2459. doi:10.1182/blood-2015-12-688705.
  • Khoury H, Dalal BI, Nevill TJ, et al. Acute myelogenous leukemia with t(8;21)–identification of a specific immunophenotype. Leuk Lymphoma. 2003;44(10):1713–1718. doi:10.1080/1042819031000116698.
  • Appelbaum FR, Kopecky KJ, Tallman MS, et al. The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations. Br J Haematol. 2006;135(2):165–173. doi:10.1111/j.1365-2141.2006.06276.x.
  • Matsuura S, Yan M, Lo MC, et al. Negative effects of GM-CSF signaling in a murine model of t(8;21)-induced leukemia. Blood. 2012;119(13):3155–3163. doi:10.1182/blood-2011-04-350694.
  • Liu XP, Xue YP, Liu SH, et al. [An analysis of cytogenetic characteristics and prognosis of 189 t (8; 21) acute myeloid leukemia patients]. Zhonghua nei ke za zhi. 2006;45(11):918–921.
  • Parihar M, Kumar JA, Sitaram U, et al. Cytogenetic analysis of acute myeloid leukemia with t(8;21) from a tertiary care center in India with correlation between clinicopathologic characteristics and molecular analysis. Leuk Lymphoma. 2012;53(1):103–109. doi:10.3109/10428194.2011.603447.
  • Zhu CY, Yang H, Niu JH, et al. [Clinical analysis of acute myeloid leukemia with t(8;21) (q22;q22) and loss of Y chromosome]. Zhongguo shi yan xue ye xue za zhi. 2014;22(4):950–956. doi:10.7534/j.issn.1009-2137.2014.04.013.
  • Zhou W, Chen G, Gong D, et al. Loss of the Y chromosome predicts a high relapse risk in younger adult male patients with t(8;21) acute myeloid leukemia on high-dose cytarabine consolidation therapy: a retrospective multicenter study. Leuk Lymphoma. 2020;61(4):820–830. doi:10.1080/10428194.2019.1683734.
  • Jung HA, Maeng CH, Park S, et al. Prognostic factor analysis in core-binding factor-positive acute myeloid leukemia. Anticancer Res. 2014;34(2):1037–1045.
  • Krauth MT, Eder C, Alpermann T, et al. High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome. Leukemia. 2014;28(7):1449–1458. doi:10.1038/leu.2014.4.
  • Schoch C, Haase D, Haferlach T, et al. Fifty-one patients with acute myeloid leukemia and translocation t(8;21)(q22;q22): an additional deletion in 9q is an adverse prognostic factor. Leukemia. 1996;10(8):1288–1295.
  • Shaffer L, Mcgowanjoran J, Schmid M, et al. (2013). ISCN 2013: An International System for Human Cytogenetic Nomenclature.
  • Wang L, Xu WL, Meng HT, et al. FLT3 and NPM1 mutations in Chinese patients with acute myeloid leukemia and normal cytogenetics. Journal of Zhejiang University Science B. 2010;11(10):762–770. doi:10.1631/jzus.B1000052.
  • Cheson BD, Bennett JM, Kopecky KJ, et al. Revised recommendations of the International working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 2003;21(24):4642–4649. doi:10.1200/jco.2003.04.036.
  • Kuchenbauer F, Schnittger S, Look T, et al. Identification of additional cytogenetic and molecular genetic abnormalities in acute myeloid leukaemia with t(8;21)/AML1-ETO. Br J Haematol. 2006;134(6):616–619. doi:10.1111/j.1365-2141.2006.06229.x.
  • Kuchenbauer F, Feuring-Buske M, Buske C. AML1-ETO needs a partner: new insights into the pathogenesis of t(8;21) leukemia. Cell Cycle (Georgetown, Tex). 2005;4(12):1716–1718. doi:10.4161/cc.4.12.2256.

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