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Hematology Volume 27, 2022 - Issue 1
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Research Article

H22954, a long non-coding RNA, inhibits glucose uptake in leukemia cells in a GLUT10-dependent manner

Yujia Baia Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China;b National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, Suzhou, People’s Republic of China;c Institute of Blood and Marrow Transplantation, Suzhou, People’s Republic of ChinaView further author information
,
Bibo Yea Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China;b National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, Suzhou, People’s Republic of China;d Cyrus Tang Hematology Center, Soochow University, Suzhou, People’s Republic of ChinaView further author information
,
Tianyu Lie Department of Hematology, Children’s Hospital of Wu Xi, Wuxi, People’s Republic of ChinaView further author information
,
Rongrong Wanga Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China;b National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, Suzhou, People’s Republic of China;c Institute of Blood and Marrow Transplantation, Suzhou, People’s Republic of ChinaView further author information
&
Xiaofei Qia Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China;b National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, Suzhou, People’s Republic of China;c Institute of Blood and Marrow Transplantation, Suzhou, People’s Republic of China;d Cyrus Tang Hematology Center, Soochow University, Suzhou, People’s Republic of China;f Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China;g State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0879-7344View further author information
ORCID Icon
Pages 469-475 | Published online: 12 Apr 2022

References

  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–674.
  • Warburg O. On the origin of cancer cells. Science. 1956;123(3191):309–314.
  • Warburg O. On respiratory impairment in cancer cells. Science. 1956;124(3215):269–270.
  • Chen WL, Wang YY, Zhao A, et al. Enhanced fructose utilization mediated by SLC2A5 is a unique metabolic feature of acute myeloid leukemia with therapeutic potential. Cancer Cell. 2016;30(5):779–791.
  • Song K, Li M, Xu X, et al. Resistance to chemotherapy is associated with altered glucose metabolism in acute myeloid leukemia. Oncol Lett. 2016;12(1):334–342.
  • Chen WL, Wang JH, Zhao AH, et al. A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value. Blood. 2014;124(10):1645–1654.
  • Wang JH, Chen WL, Li JM, et al. Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China. Proc Natl Acad Sci U S A. 2013;110(42):17017–17022.
  • Hulleman E, Kazemier KM, Holleman A, et al. Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells. Blood. 2009;113(9):2014–2021.
  • Tilekar K, Upadhyay N, Hess JD, et al. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020;202:112603.
  • Qi X, Jiao Y, Cheng C, et al. H22954, a novel long non-coding RNA down-regulated in AML, inhibits cancer growth in a BCL-2-dependent mechanism. Cancer Lett. 2019;454:26–36.
  • Qi X, Chen Z, Liu D, et al. Expression of Dlk1 gene in myelodysplastic syndrome determined by microarray, and its effects on leukemia cells. Int J Mol Med. 2008;22(1):61–68.
  • Qi X, Jiang J, Zhu M, et al. Human corin isoforms with different cytoplasmic tails that alter cell surface targeting. J Biol Chem. 2011;286(23):20963–20969.
  • Ye B, Zhou Y, Liu Y, et al. Pulsatilla saponin A induces apoptosis and differentiation of myeloma cells. Anticancer Agents Med Chem. 2021;21(7):919–926.
  • Wang ZX, Zhang B, Deng SM, et al. Early evaluation for treatment efficacy of 5-fluorouracil and hyperthermia on HCT-116 colon cancer cells by fluorine-18-fluorodeoxyglucose uptake. Chin Med J (Engl). 2012;125(4):657–661.
  • Zhang LF, Lou JT, Lu MH, et al. Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma. EMBO J. 2015;34(21):2671–2685.
  • Lan Z, Yao X, Sun K, et al. The interaction between lncRNA SNHG6 and hnRNPA1 contributes to the growth of colorectal cancer by enhancing aerobic glycolysis through the regulation of alternative splicing of PKM. Front Oncol. 2020;10:363.
  • Wang C, Li Y, Yan S, et al. Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2. Nat Commun. 2020;11(1):3162.

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