Bendamustine treatment of haematological malignancies: significant risks of opportunistic viral, fungal and bacterial infections

References

• Vidal L, Gurion R, Shargian L, et al. Bendamustine for patients with indolent B cell lymphoproliferative malignancies including chronic lymphocytic leukaemia - an updated meta-analysis. Br J Haematol. 2019;186(2):234–242.
   PubMed Web of Science ®Google Scholar
• Broccoli A, Argnani L, Zinzani PL. Peripheral T-cell lymphomas: focusing on novel agents in relapsed and refractory disease. Cancer Treat Rev. 2017;60:120–129.
   PubMed Web of Science ®Google Scholar
• Gentile M, Vigna E, Recchia AG, et al. Bendamustine in multiple myeloma. Eur J Haematol. 2015;95(5):377–388.
   PubMed Web of Science ®Google Scholar
• Gafter-Gvili A, Gurion R, Raanani P, et al. Bendamustine-associated infections-systematic review and meta-analysis of randomized controlled trials. Hematol Oncol. 2017;35(4):424–431.
   PubMed Web of Science ®Google Scholar
• Fung M, Jacobsen E, Freedman A, et al. Increased risk of infectious complications in older patients with indolent non-Hodgkin lymphoma exposed to bendamustine. Clin Infect Dis. 2019;68(2):247–255.
   PubMed Web of Science ®Google Scholar
• Gafter-Gvili A, Polliack A. Bendamustine associated immune suppression and infections during therapy of hematological malignancies. Leuk Lymphoma. 2016;57(3):512–519.
   PubMed Web of Science ®Google Scholar
• Foukaneli T, Kerr P, Bolton-Maggs PHB, et al. Guidelines on the use of irradiated blood components. Br J Haematol. 2020;191(5):704–724.
   PubMed Web of Science ®Google Scholar
• Chan TS, Cheng SS, Chen WT, et al. Cost-effectiveness of letermovir as cytomegalovirus prophylaxis in adult recipients of allogeneic hematopoietic stem cell transplantation in Hong Kong. J Med Econ. 2020;23(12):1485–1492.
   PubMed Web of Science ®Google Scholar
• Ljungman P, Boeckh M, Hirsch HH, et al. Definitions of Cytomegalovirus infection and disease in transplant patients for Use in clinical trials. Clin Infect Dis. 2017;64(1):87–91.
   PubMed Web of Science ®Google Scholar
• Donnelly JP, Chen SC, Kauffman CA, et al. Revision and update of the consensus definitions of invasive fungal disease from the European Organization for research and treatment of Cancer and the Mycoses study group education and research consortium. Clin Infect Dis. 2020;71(6):1367–1376.
   PubMed Web of Science ®Google Scholar
• Gafter-Gvili A, Ribakovsky E, Mizrahi N, et al. Infections associated with bendamustine containing regimens in hematological patients: a retrospective multi-center study. Leuk Lymphoma. 2016;57(1):63–69.
   PubMed Web of Science ®Google Scholar
• Hosoda T, Yokoyama A, Yoneda M, et al. Bendamustine can severely impair T-cell immunity against cytomegalovirus. Leuk Lymphoma. 2013;54(6):1327–1328.
   PubMed Web of Science ®Google Scholar
• Hasegawa T, Aisa Y, Shimazaki K, et al. Cytomegalovirus reactivation with bendamustine in patients with low-grade B-cell lymphoma. Ann Hematol. 2015;94(3):515–517.
   PubMed Web of Science ®Google Scholar
• Isono N, Imai Y, Watanabe A, et al. Cytomegalovirus reactivation in low-grade B-cell lymphoma patients treated with bendamustine. Leuk Lymphoma. 2016;57(9):2204–2207.
   PubMed Web of Science ®Google Scholar
• Port AD, Orlin A, Kiss S, et al. Cytomegalovirus retinitis: a review. J Ocul Pharmacol Ther. 2017;33(4):224–234.
   PubMed Web of Science ®Google Scholar
• Chan TS, Cheung CY, Yeung IY, et al. Cytomegalovirus retinitis complicating combination therapy with rituximab and fludarabine. Ann Hematol. 2015;94(6):1043–1047.
   PubMed Web of Science ®Google Scholar
• Iu LP, Fan MC, Lau JK, et al. Long-term follow-up of Cytomegalovirus retinitis in non-HIV immunocompromised patients: clinical features and visual prognosis. Am J Ophthalmol. 2016;165:145–153.
   PubMed Web of Science ®Google Scholar
• Vinters HV, Kwok MK, Ho HW, et al. Cytomegalovirus in the nervous system of patients with the acquired immune deficiency syndrome. Brain. 1989;112(Pt 1):245–268.
   PubMedGoogle Scholar
• Chiba A, Nakamura F, Nakazaki K, et al. Cytomegalovirus antigenemia and end-organ disease in Japanese patients treated with bendamustine. Leuk Lymphoma. 2018;59(3):749–751.
   PubMed Web of Science ®Google Scholar
• Cona A, Tesoro D, Chiamenti M, et al. Disseminated cytomegalovirus disease after bendamustine: a case report and analysis of circulating B- and T-cell subsets. BMC Infect Dis. 2019;19(1):881.
   PubMed Web of Science ®Google Scholar
• Bate SL, Dollard SC, Cannon MJ. Cytomegalovirus seroprevalence in the United States: the national health and nutrition examination surveys, 1988–2004. Clin Infect Dis. 2010;50(11):1439–1447.
   PubMed Web of Science ®Google Scholar
• Marshall GS, Stout GG. Cytomegalovirus seroprevalence among women of childbearing age during a 10-year period. Am J Perinatol. 2005;22(7):371–376.
   PubMed Web of Science ®Google Scholar
• Nishimura N, Kimura H, Yabuta Y, et al. Prevalence of maternal cytomegalovirus (CMV) antibody and detection of CMV DNA in amniotic fluid. Microbiol Immunol. 1999;43(8):781–784.
   PubMed Web of Science ®Google Scholar
• Taplitz RA, Kennedy EB, Bow EJ, et al. Antimicrobial prophylaxis for adult patients with cancer-related immunosuppression: ASCO and IDSA clinical practice guideline update. J Clin Oncol. 2018;36(30):3043–3054.
   PubMed Web of Science ®Google Scholar
• Chen R, Zhang Y, Zhou P, et al. Cryptococcemia according to immune status: An analysis of 65 critical cases. Infect Dis Ther. 2021;10(1):363–371.
   PubMed Web of Science ®Google Scholar
• Lionakis MS, Lewis RE, Kontoyiannis DP. Breakthrough invasive mold infections in the hematology patient: current concepts and future directions. Clin Infect Dis. 2018;67(10):1621–1630.
   PubMed Web of Science ®Google Scholar
• Khodavaisy S, Badali H, Meis JF, et al. Comparative in vitro activities of seven antifungal drugs against clinical isolates of Candida parapsilosis complex. J Mycol Med. 2020;30(3):100968.
   PubMed Web of Science ®Google Scholar
• Sarlo KM, Dixon BN, Ni A, et al. Incidence of infectious complications with the combination of bendamustine and an anti-CD20 monoclonal antibody. Leuk Lymphoma. 2020;61(2):364–369.
   PubMed Web of Science ®Google Scholar
• Huang Y, Li T, Yu H, et al. Maternal CMV seroprevalence rate in early gestation and congenital cytomegalovirus infection in a Chinese population. Emerg Microbes Infect. 2021;10(1):1824–1831.
   PubMed Web of Science ®Google Scholar