Advanced search
Publication Cover
Hematology Volume 27, 2022 - Issue 1
Submit an article Journal homepage
1,551
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Role of Tfh17 cells in patients with multiple myeloma

Chunmei Yea Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of China;b Department of Clinical Laboratory, Jinhua Municipal Central Hospital, Jinhua Hospital of Zhejiang University, Jinhua, People’s Republic of China
,
Yuni Xuc Department of laboratory medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, People’s Republic of China
,
Zhenni Wanga Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of China
,
Yanxia Chend Center for General Practice Medicine, Department of Rheumatology and Immunology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of China
&
Jinlin Liua Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0003-0502-4813
ORCID Icon
Pages 820-825 | Published online: 29 Jul 2022

References

  • Bergstrom DJ, Kotb R, Louzada ML, et al. Consensus guidelines on the diagnosis of multiple myeloma and related disorders: recommendations of the myeloma Canada research network consensus guideline consortium. Clin Lymphoma Myeloma Leuk. Jul 2020;20(7):e352–e367.
  • Breitfeld D, Ohl L, Kremmer E, et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med. Dec 4 2000;192(11):1545–1552.
  • Crotty S. T follicular helper cell biology: A decade of discovery and diseases. Immunity. 2019;50(5):1132–1148.
  • Akkaya M, Traba J, Roesler AS, et al. Second signals rescue B cells from activation-induced mitochondrial dysfunction and death. Nat Immunol. Aug 2018;19(8):871–884.
  • Morita R, Schmitt N, Bentebibel SE, et al. Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity. Jan 28 2011;34(1):108–121.
  • Utley A, Lipchick B, Lee KP, et al. Targeting multiple myeloma through the biology of long-lived plasma cells. Cancers (Basel). 2020;12(8.
  • Wu X, Fajardo-Despaigne JE, Zhang C, et al. Altered T follicular helper cell subsets and function in chronic lymphocytic leukemia. Front Oncol. 2021;11:674492.
  • Zhou DM, Xu YX, Zhang LY, et al. The role of follicular T helper cells in patients with malignant lymphoid disease. Hematology. 2017;22(7):412–418.
  • Kyle RA, Rajkumar SV. Spotlight review series on multiple myeloma. Leukemia. 2009;23(1):R1–R2.
  • Minnie SA, Kuns RD, Gartlan KH, et al. Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade. Blood, J Am Soc Hematol. Oct 18 2018;132(16):1675–1688.
  • Nakamura K, Smyth MJ, Martinet L. Cancer immunoediting and immune dysregulation in multiple myeloma. Blood. Dec 10 2020;136(24):2731–2740.
  • Yu D, Rao S, Tsai LM, et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity. Sep 18 2009;31(3):457–468.
  • Vaca AM, Ioannou N, Sivina M, et al. Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures. Leukemia. Feb 11 2022.
  • Dai L, He L, Wang Z, et al. Altered circulating T follicular helper cells in patients with chronic immune thrombocytopenia. Exp Ther Med. Sep 2018;16(3):2471–2477.
  • Ma T, Zhang Y, Zhou X, et al. A unique role of T helper 17 cells in different treatment stages of multiple myeloma. Clin Lymphoma Myeloma Leukemia. 2020;20(3):190–197.
  • Prabhala RH, Pelluru D, Fulciniti M, et al. Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma. Blood. Jul 1 2010;115(26):5385–5392.
  • Prabhala RH, Fulciniti M, Pelluru D, et al. Targeting IL-17A in multiple myeloma: a potential novel therapeutic approach in myeloma. Leukemia. 2016;30(2):379–389.
  • Lee AYS, Körner H. The CCR6-CCL20 axis in humoral immunity and T-B cell immunobiology. Immunobiology. 2019;224(3):449–454.
  • Kadomoto S, Izumi K, Mizokami A. The CCL20-CCR6 axis in cancer progression. Int J Mol Sci. Jul 22 2020;21(15.
  • Korbecki J, Grochans S, Gutowska I, et al. CC chemokines in a tumor: A review of Pro-cancer and anti-cancer properties of receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 ligands. Int J Mol Sci. Oct 15 2020;21(20.
  • Giuliani N, Lisignoli G, Colla S, et al. CC-chemokine ligand 20/macrophage inflammatory protein-3α and CC-chemokine receptor 6 are overexpressed in myeloma microenvironment related to osteolytic bone lesions. Cancer Res. Aug 15 2008;68(16):6840–6850.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.