781
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Spliced X-Box binding protein 1 predicts satisfying responsiveness and survival benefit toward bortezomib-based therapy in multiple myeloma patients

, &

References

  • Medical Masterclass c, Firth J. Haematology: multiple myeloma. Clin Med (Lond). 2019;19(1):58–60. doi:10.7861/clinmedicine.19-1-58
  • Joshua DE, Bryant C, Dix C, et al. Biology and therapy of multiple myeloma. Med J Aust. 2019;210(8):375–380. doi:10.5694/mja2.50129
  • Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660
  • Lussier T, Schoebe N, Mai S. Risk stratification and treatment in smoldering multiple myeloma. Cells. 2022;11(1. doi:10.3390/cells11010130
  • Podar K, Leleu X. Relapsed/refractory multiple myeloma in 2020/2021 and beyond. Cancers (Basel). 2021;13(20. doi:10.3390/cancers13205154
  • Dimopoulos MA, Moreau P, Terpos E, et al. Multiple myeloma: EHA-ESMO clinical practice guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2021;32(3):309–322. doi:10.1016/j.annonc.2020.11.014
  • Sonneveld P, Avet-Loiseau H, Lonial S, et al. Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the international myeloma working group. Blood. 2016;127(24):2955–2962. doi:10.1182/blood-2016-01-631200
  • Hemminki K, Forsti A, Hansson M. Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016. Sci Rep. 2021;11(1):17272. doi:10.1038/s41598-021-96804-8
  • Yang FY, Wang HF, Xia LH, et al. A propensity score matching study of autologous hematopoietic stem cell transplantation and New drug chemotherapy for newly diagnosed multiple myeloma. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2022;30(1):158–165.
  • Yoshida H, Nadanaka S, Sato R, et al. XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from site-2 protease-deficient Chinese hamster ovary cells. Cell Struct Funct. 2006;31(2):117–125. doi:10.1247/csf.06016
  • Xu W, Wang C, Hua J. X-box binding protein 1 (XBP1) function in diseases. Cell Biol. Int. 2021;45(4):731–739. doi:10.1002/cbin.11533
  • Zhang D, De Veirman K, Fan R, et al. ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation. Stem Cell Res Ther. 2020;11(1):516. doi:10.1186/s13287-020-02037-3
  • Bujisic B, De Gassart A, Tallant R, et al. Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth. Blood. 2017;129(17):2420–2428. doi:10.1182/blood-2016-09-741348
  • Luo X, Alfason L, Wei M, et al. Spliced or unspliced, that Is the question: The biological roles of XBP1 isoforms in pathophysiology. Int J Mol Sci. 2022;23(5).
  • Park SM, Kang TI, So JS. Roles of XBP1s in transcriptional regulation of target genes. Biomedicines. 2021;9(7).
  • Song M, Sandoval TA, Chae CS, et al. IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. 2018;562(7727):423–428. doi:10.1038/s41586-018-0597-x
  • Ji H, Huang C, Wu S, et al. XBP1-s promotes colorectal cancer cell proliferation by inhibiting TAp73 transcriptional activity. Biochem Biophys Res Commun. 2019;508(1):203–209. doi:10.1016/j.bbrc.2018.11.112
  • Wu S, Du R, Gao C, et al. The role of XBP1s in the metastasis and prognosis of hepatocellular carcinoma. Biochem Biophys Res Commun. 2018;500(3):530–537. doi:10.1016/j.bbrc.2018.04.033
  • Besse L, Besse A, Kraus M, et al. High immunoproteasome activity and sXBP1 in pediatric precursor B-ALL predicts sensitivity towards proteasome inhibitors. Cells. 2021;10(11). doi:10.3390/cells10112853
  • Cui Y, Xu H, Yang Y, et al. The regulation of miR-320a/XBP1 axis through LINC00963 for endoplasmic reticulum stress and autophagy in diffuse large B-cell lymphoma. Cancer Cell Int. 2021;21(1):305. doi:10.1186/s12935-021-01992-y
  • Borjan B, Kern J, Steiner N, et al. Spliced XBP1 levels determine sensitivity of multiple myeloma cells to proteasome inhibitor bortezomib independent of the unfolded protein response mediator GRP78. Front Oncol. 2020;9:1530. doi:10.3389/fonc.2019.01530
  • Ludwig H, Miguel JS, Dimopoulos MA, et al. International myeloma working group recommendations for global myeloma care. Leukemia. 2014;28(5):981–992. doi:10.1038/leu.2013.293
  • Durie BG, Salmon SE. A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer. 1975;36(3):842–854. doi:10.1002/1097-0142(197509)36:3<842::AID-CNCR2820360303>3.0.CO;2-U
  • Greipp PR, San Miguel J, Durie BG, et al. International staging system for multiple myeloma. J Clin Oncol. 2005;23(15):3412–3420. doi:10.1200/JCO.2005.04.242
  • Palumbo A, Avet-Loiseau H, Oliva S, et al. Revised international staging system for multiple myeloma: A report from international myeloma working group. J Clin Oncol. 2015;33(26):2863–2869. doi:10.1200/JCO.2015.61.2267
  • Wang Y, Osakue D, Yang E, et al. Endoplasmic reticulum stress response of trabecular meshwork stem cells and trabecular meshwork cells and protective effects of activated PERK pathway. Invest Ophthalmol Vis Sci. 2019;60(1):265–273. doi:10.1167/iovs.18-25477
  • Moreau P, Avet-Loiseau H, Facon T, et al. Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma. Blood. 2011;118(22):5752–5758. quiz 5982. doi:10.1182/blood-2011-05-355081
  • Rajkumar SV, Harousseau JL, Durie B, et al. Consensus recommendations for the uniform reporting of clinical trials: Report of the international myeloma workshop consensus panel 1. Blood. 2011;117(18):4691–4695. doi:10.1182/blood-2010-10-299487
  • Bortolozzi R, Viola G, Porcu E, et al. A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents. Oncotarget. 2014;5(15):5978–5991. doi:10.18632/oncotarget.2027
  • Bae J, Hideshima T, Zhang GL, et al. Identification and characterization of HLA-A24-specific XBP1, CD138 (Syndecan-1) and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma. Leukemia. 2018;32(3):752–764. doi:10.1038/leu.2017.316
  • Reimold AM, Iwakoshi NN, Manis J, et al. Plasma cell differentiation requires the transcription factor XBP-1. Nature. 2001;412(6844):300–307. doi:10.1038/35085509
  • Todd DJ, McHeyzer-Williams LJ, Kowal C, et al. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med. 2009;206(10):2151–2159. doi:10.1084/jem.20090738
  • Chen L, Li Q, She T, et al. IRE1α-XBP1 signaling pathway, a potential therapeutic target in multiple myeloma. Leuk Res. 2016;49:7–12. doi:10.1016/j.leukres.2016.07.006
  • Tavernier Q, Mami I, Rabant M, et al. Urinary angiogenin reflects the magnitude of kidney injury at the infrahistologic level. J Am Soc Nephrol. 2017;28(2):678–690. doi:10.1681/ASN.2016020218
  • Schardt JA, Weber D, Eyholzer M, et al. Activation of the unfolded protein response is associated with favorable prognosis in acute myeloid leukemia. Clin Cancer Res. 2009;15(11):3834–3841. doi:10.1158/1078-0432.CCR-08-2870