References
- Joshua DE, Bryant C, Dix C, et al. Biology and therapy of multiple myeloma. Med J Aust. 2019;210:375–380.
- Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70:7–30.
- van de Donk N, Pawlyn C, Yong KL. Multiple myeloma. Lancet. 2021;397:410–427.
- Bobin A, Liuu E, Moya N, et al. Multiple myeloma: An overview of the current and novel therapeutic approaches in 2020. Cancers (Basel). 2020;12:2885. https://doi.org/10.3390/cancers12102885
- Pinto V, Bergantim R, Caires HR, et al. Multiple myeloma: available therapies and causes of drug resistance. Cancers (Basel). 2020;12:407. https://doi.org/10.3390/cancers12020407
- Kang B, Park H, Kim B. Anticancer activity and underlying mechanism of phytochemicals against multiple myeloma. Int J Mol Sci. 2019;20:2302. https://doi.org/10.3390/ijms20092302
- Zhu F, Jiang D, Zhang M, et al. 2,4-Dihydroxy-3'-methoxy-4'-ethoxychalcone suppresses cell proliferation and induces apoptosis of multiple myeloma via the PI3K/akt/mTOR signaling pathway. Pharm Biol. 2019;57:641–648.
- Cicconi L, Platzbecker U, Avvisati G, et al. Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial. Leukemia. 2020;34:914–918.
- Roschewski M, Dunleavy K, Abramson JS, et al. Multicenter study of risk-adapted therapy With dose-adjusted EPOCH-R in adults With untreated burkitt lymphoma. J Clin Oncol. 2020;38:2519–2529.
- Zhang Z, Jiang M, Borthakur G, et al. Acute myeloid leukemia with a novel CPSF6-RARG variant is sensitive to homoharringtonine and cytarabine chemotherapy. Am J Hematol. 2020;95:E48–E51.
- Yin L, Shi C, Zhang Z, et al. Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-kappaB inhibition in macrophages. Korean J Physiol Pharmacol. 2021;25:395–401.
- Xiao X, Yang M, Xiao J, et al. Paris saponin II suppresses the growth of human ovarian cancer xenografts via modulating VEGF-mediated angiogenesis and tumor cell migration. Cancer Chemother Pharmacol. 2014;73:807–818.
- Li Y, Man S, Li J, et al. The antitumor effect of formosanin C on HepG2 cell as revealed by 1H-NMR based metabolic profiling. Chem Biol Interact. 2014;220:193–199.
- Man S, Zhang L, Cui J, et al. Curcumin enhances the anti-cancer effects of Paris saponin II in lung cancer cells. Cell Prolif. 2018;51:e12458.
- Yang M, Zou J, Zhu H, et al. Paris saponin II inhibits human ovarian cancer cell-induced angiogenesis by modulating NF-kappaB signaling. Oncol Rep. 2015;33:2190–2198.
- Chen M, Ye K, Zhang B, et al. Paris saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-kappaB pathway. Pharmacol Res. 2019;139:273–285.
- Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132:27–42.
- Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med. 2013;368:651–662.
- White E. Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer. 2012;12:401–410.
- Galluzzi L, Vitale I, Abrams JM, et al. Molecular definitions of cell death subroutines: recommendations of the nomenclature committee on cell death 2012. Cell Death Differ. 2012;19:107–120.
- Yun Z, Zhichao J, Hao Y, et al. Targeting autophagy in multiple myeloma. Leuk Res. 2017;59:97–104.
- Desantis V, Saltarella I, Lamanuzzi A, et al. Autophagy: A New mechanism of prosurvival and drug resistance in multiple myeloma. Transl Oncol. 2018;11:1350–1357.
- Zhang H, Dong X, Zhao R, et al. Cadmium results in accumulation of autophagosomes-dependent apoptosis through activating Akt-impaired autophagic flux in neuronal cells. Cell Signal. 2019;55:26–39.
- Mizushima N, Levine B, Cuervo AM, et al. Autophagy fights disease through cellular self-digestion. Nature. 2008;451:1069–1075.
- Zhang L, Man S, Wang Y, et al. Paris saponin II induced apoptosis via activation of autophagy in human lung cancer cells. Chem Biol Interact. 2016;253:125–133.
- Li A, Chen X, Jing Z, et al. Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma. FEBS Open Bio. 2020;10:2097–2106.
- Wang G, Zhou P, Chen X, et al. The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis. Cancer Biol Ther. 2017;18:584–595.
- Carroll RG, Martin SJ. Autophagy in multiple myeloma: what makes you stronger can also kill you. Cancer Cell. 2013;23:425–426.
- Pengo N, Scolari M, Oliva L, et al. Plasma cells require autophagy for sustainable immunoglobulin production. Nat Immunol. 2013;14:298–305.
- Roy M, Liang L, Xiao X, et al. Lycorine downregulates HMGB1 to inhibit autophagy and enhances bortezomib activity in multiple myeloma. Theranostics. 2016;6:2209–2224.
- Zheng Z, Wang L, Cheng S, et al. Autophagy and myeloma. Adv Exp Med Biol. 2020;1207:625–631.
- Zhao Y, Zhang E, Lv N, et al. Metformin and FTY720 synergistically induce apoptosis in multiple myeloma cells. Cell Physiol Biochem. 2018;48:785–800.
- Jaouadi O, Limam I, Abdelkarim M, et al. 5,6-Epoxycholesterol isomers induce oxiapoptophagy in myeloma cells. Cancers (Basel). 2021;13:3747. https://doi.org/10.3390/cancers13153747
- Dong X, Zuo Y, Zhou M, et al. Bortezomib activation of mTORC1 pathway mediated by NOX2-drived reactive oxygen species results in apoptosis in primary dorsal root ganglion neurons. Exp Cell Res. 2021;400:112494.
- Rampen AJ, Jongen JL, van Heuvel I, et al. Bortezomib-induced polyneuropathy. Neth J Med. 2013;71:128–133.