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Research Article

Indicators of stress hematopoiesis in the blood predict COVID-19 progression in patients over 65 years old

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Article: 2311006 | Received 23 Jul 2023, Accepted 23 Jan 2024, Published online: 02 Feb 2024

References

  • Sayyadi M, Hassani S, Shams M, et al. Status of major hemostatic components in the setting of COVID-19: the effect on endothelium, platelets, coagulation factors, fibrinolytic system, and complement. Ann Hematol. 2023;102(6):1307–1322. doi:10.1007/s00277-023-05234-1
  • Delshad M, Safaroghli-Azar A, Pourbagheri-Sigaroodi A, et al. Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunity. Int Immunopharmacol. 2021;99:107995. doi:10.1016/j.intimp.2021.107995
  • Chen H, Yang G, Long Y, et al. Lymphocyte and platelet counts, as well as interleukin-6 levels, predict mortality of coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis. Evid Based Complement Alternat Med. 2021;2021:5582908. doi:10.1155/2021/5582908
  • Capitano ML. Toll-like receptor signaling in hematopoietic stem and progenitor cells. Curr Opin Hematol. 2019;26(4):207–213. doi:10.1097/MOH.0000000000000511
  • Huerga Encabo H, Grey W, Garcia-Albornoz M, et al. Human erythroid progenitors are directly infected by SARS-CoV-2: implications for emerging erythropoiesis in severe COVID-19 patients. Stem Cell Rep. 2021;16(3):428–436. doi:10.1016/j.stemcr.2021.02.001
  • Elahi S. Hematopoietic responses to SARS-CoV-2 infection. Cell Mol Life Sci. 2022 Mar 13;79(3):187. doi:10.1007/s00018-022-04220-6
  • Zhao JL, Ma C, O’Connell RM, et al. Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis. Cell Stem Cell. 2014;14(4):445–459. doi:10.1016/j.stem.2014.01.007
  • Vadillo E, Taniguchi-Ponciano K, Lopez-Macias C, et al. A shift towards an immature myeloid profile in peripheral blood of critically Ill COVID-19 patients. Arch Med Res. 2021;52(3):311–323. doi:10.1016/j.arcmed.2020.11.005
  • Baldridge MT, King KY, Goodell MA. Inflammatory signals regulate hematopoietic stem cells. Trends Immunol. 2011;32:57–65. doi:10.1016/j.it.2010.12.003
  • Yamashita M, Passegué E. TNF-α coordinates hematopoietic stem cell survival and myeloid regeneration. Cell Stem Cell. 2019;25(3):357–372.e7. doi:10.1016/j.stem.2019.05.019
  • Schulte-Schrepping J, Reusch N, Paclik D, et al. Deutsche COVID-19 OMICS initiative (DeCOI). severe COVID-19 Is marked by a dysregulated myeloid cell compartment. Cell. 2020;182(6):1419–1440.e23. doi:10.1016/j.cell.2020.08.001
  • Ayres LS, Sgnaolin V, Munhoz TP. Immature granulocytes index as early marker of sepsis. Int J Lab Hematol. 2019;41(3):392–396. doi:10.1111/ijlh.12990
  • Salminen A. Immunosuppressive network promotes immunosenescence associated with aging and chronic inflammatory conditions. J Mol Med. 2021;99:1553–1569. doi:10.1007/s00109-021-02123-w
  • Milenkovic J, Djindjic B, Djordjevic B, et al. Platelet-derived immuno-inflammatory indices show best performance in early prediction of COVID-19 progression. J Clin Lab Anal. 2022;36(9):e24652. doi:10.1002/jcla.24652
  • Lippi G, Plebani M, Henry B. Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis. Clin Chim Acta. 2020;506:145–148. doi:10.1016/j.cca.2020.03.022
  • Muady GF, Bitterman H, Laor A, et al. Hemoglobin levels and blood transfusion in patients with sepsis in internal medicine departments. BMC Infect Dis. 2016;16:569. doi:10.1186/s12879-016-1882-7
  • Jandaghian S, Vaezi A, Manteghinejad A, et al. Red blood cell distribution width (RDW) as a predictor of in-hospital mortality in COVID-19 patients; a cross sectional study. Arch Acad Emerg Med. 2021;9(1):e67. doi:10.22037/aaem.v9i1.1325
  • Zhang RDW, Zhang J, Hu J, et al. Association between red blood cell distribution width and COVID-19 severity in delta variant SARS-CoV-2 infection. Front Med (Lausanne). 2022;9:837411. doi:10.3389/fmed.2022.837411
  • Akbari H, Tabrizi R, Lankarani KB, et al. The role of cytokine profile and lymphocyte subsets in the severity of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis. Life Sci. 2020;258:118167. doi:10.1016/j.lfs.2020.118167
  • Chaudhary N, Raju K, Kamarthi P. Profile of platelet parameters in coronavirus disease – positive cases — an observational study. BMRAT. 2021;8(10):4649–4654. doi:10.15419/bmrat.v8i10.700
  • Wool GD, Miller JL. The impact of COVID-19 disease on platelets and coagulation. Pathobiology. 2021;88(1):15–27. doi:10.1159/000512007
  • Ahmadi E, Bagherpour Z, Zarei E, et al. Pathological effects of SARS-CoV-2 on hematological and immunological cells: alterations in count, morphology, and function [published online ahead of print, 2022 Jan 29]. Pathol Res Pract. 2022;231:153782. doi:10.1016/j.prp.2022.153782
  • Zhao Q, Meng M, Kumar R, et al. Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a systemic review and meta-analysis. Int J Infect Dis. 2020;96:131–135. doi:10.1016/j.ijid.2020.04.086
  • Didangelos A. COVID-19 hyperinflammation: what about neutrophils? mSphere. 2020 Jun 24;5(3):e00367–20. doi:10.1128/mSphere.00367-20
  • Daniels S, Wei H, van Tongeren M, et al. Are platelet volume indices of clinical use in COVID-19? A systematic review. Front Cardiovasc Med. 2022;9:1031092. doi:10.3389/fcvm.2022.1031092
  • Romo-Rodríguez R, Gutiérrez-de Anda K, López-Blanco JA, et al. Chronic comorbidities in middle aged patients contribute to ineffective emergency hematopoiesis in COVID-19 fatal outcomes. Arch Med Res. 2023;54(3):197–210. doi:10.1016/j.arcmed.2023.03.003
  • Tzur I, Barchel D, Izhakian S, et al. Platelet distribution width: a novel prognostic marker in an internal medicine ward. J Community Hosp Intern Med Perspect. 2019;9(6):464–470. doi:10.1080/20009666.2019.1688095
  • Du RH, Liang LR, Yang CQ, et al. Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study. Eur Respir J. 2020;55(5):2000524. doi:10.1183/13993003.00524-2020
  • Bleve A, Motta F, Durante B, et al. Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases. Clin Rev Allergy Immunol. 2023;64(2):123–144. doi:10.1007/s12016-021-08909-7
  • Hodcroft E. CoVariants: SARS-CoV-2 mutations and variants of interest [CoVariants website]. https://covariants.org/. Accessed Dec 22, 2023.
  • Scheller J, Chalaris A, Schmidt-Arras D, et al. The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta. 2011 May;1813(5):878–888. doi:10.1016/j.bbamcr.2011.01.034
  • Bektas A, Schurman SH, Sen R, et al. Human T cell immunosenescence and inflammation in aging. J Leukoc Biol. 2017;102(4):977–988. doi:10.1189/jlb.3RI0716-335R
  • Schmitt V, Rink L, Uciechowski P. The Th17/treg balance is disturbed during aging. Exp Gerontol. 2013;48(12):1379–1386. doi:10.1016/j.exger.2013.09.003
  • Schulz AR, Mälzer JN, Domingo C, et al. Low thymic activity and dendritic cell numbers are associated with the immune response to primary viral infection in elderly humans. J Immunol. 2015;195(10):4699–4711. doi:10.4049/jimmunol.1500598
  • Saito S, Shahbaz S, Sligl W, et al. Differential impact of SARS-CoV-2 isolates, namely, the Wuhan strain, delta, and omicron variants on erythropoiesis. Microbiol Spectr. 2022;10(4):e0173022. doi:10.1128/spectrum.01730-22
  • Shahbaz S, Xu L, Osman M, et al. Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2. Stem Cell Rep. 2021 May 11;16(5):1165–1181. doi:10.1016/j.stemcr.2021.04.001
  • Sarkar S, Kannan S, Khanna P, et al. Role of red blood cell distribution width, as a prognostic indicator in COVID-19: A systematic review and meta-analysis. Rev Med Virol. 2022 Mar;32(2):e2264. doi:10.1002/rmv.2264
  • Thachil J, Tang N, Gando S, et al. Laboratory haemostasis monitoring in COVID-19. J Thromb Haemost. 2020;18(8):2058–2060. doi:10.1111/jth.14866
  • Yang M, Ng MH, Li CK, et al. Thrombopoietin levels increased in patients with severe acute respiratory syndrome. Thromb Res. 2008;122(4):473–477. doi:10.1016/j.thromres.2007.12.021
  • de Sousa DMB, Poupardin R, Villeda SA, et al. The platelet transcriptome and proteome in Alzheimer's disease and aging: an exploratory cross-sectional study. Front Mol Biosci. 2023;10:1196083. doi:10.3389/fmolb.2023.1196083
  • Davizon-Castillo P, McMahon B, Aguila S, et al. TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. 2019;134(9):727–740. doi:10.1182/blood.2019000200
  • Le Blanc J, Lordkipanidzé M. Platelet function in aging. Front Cardiovasc Med. 2019;6:109. doi:10.3389/fcvm.2019.00109