Radionuclide imaging of liposomal drug delivery

References

• Bangham AD, Standish MM, Watkins JC. Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol. 1965 Aug;13:238–252.
   PubMed Web of Science ®Google Scholar
• Petersen AL, Hansen AE, Gabizon A, et al. Liposome imaging agents in personalized medicine. Adv Drug Deliv Rev. 2012 Oct;64:1417–1435.
   PubMed Web of Science ®Google Scholar
• Bozzuto G, Molinari A. Liposomes as nanomedical devices. Int J Nanomedicine. 2015;10:975–999.
   PubMed Web of Science ®Google Scholar
• Schiffelers RM, Banciu M, Metselaar JM, et al. Therapeutic application of long-circulating liposomal glucocorticoids in auto-immune diseases and cancer. J Liposome Res. 2006;16:185–194.
   PubMed Web of Science ®Google Scholar
• Bao A, Goins B, Klipper R, et al. Direct 99mTc labeling of pegylated liposomal doxorubicin (Doxil) for pharmacokinetic and non-invasive imaging studies. J Pharmacol Exp Ther. 2004 Feb;308:419–425.
   PubMed Web of Science ®Google Scholar
• Seo JW, Mahakian LM, Tam S, et al. The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model. Nucl Med Biol. 2015 Feb;42:155–163.
   PubMed Web of Science ®Google Scholar
• Zielhuis SW, Seppenwoolde J-H, Mateus VAP, et al. Lanthanide-loaded liposomes for multimodality imaging and therapy. Cancer Biother Radiopharm. 2006 Oct;21:520–527.
   PubMed Web of Science ®Google Scholar
• Phillips WT, Goins BA, Bao A. Radioactive liposomes. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Jan–Feb;1:69–83.
   PubMed Web of Science ®Google Scholar
• Liu D, Mori A, Huang L. Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes. Biochim Biophys Acta. 1992 Feb 17;1104:95–101.
   PubMed Web of Science ®Google Scholar
• Chang H-I, Yeh M-K. Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy. Int J Nanomedicine. 2012;7:49–60.
   PubMed Web of Science ®Google Scholar
• Allen TM, Cullis PR. Liposomal drug delivery systems: from concept to clinical applications. Adv Drug Deliv Rev. 2013 Jan;65:36–48.
   PubMed Web of Science ®Google Scholar
• Wang X, Song Y, Su Y, et al. Are PEGylated liposomes better than conventional liposomes? A special case for vincristine. Drug Deliv. 2015 Jun;2:1–9.
   Google Scholar
• Jahn F, Jordan K, Behlendorf T, et al. Safety and efficacy of liposomal cytarabine in the treatment of neoplastic meningitis. Oncology. 2015;89:137–142.
   PubMed Web of Science ®Google Scholar
• Cedervall T, Lynch I, Foy M, et al. Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angewandte Chemie. 2007;46:5754–5756.
   Google Scholar
• Labarre D, Vauthier C, Chauvierre C, et al. Interactions of blood proteins with poly(isobutylcyanoacrylate) nanoparticles decorated with a polysaccharidic brush. Biomaterials. 2005 Aug;26:5075–5084.
   PubMed Web of Science ®Google Scholar
• Lundqvist M, Stigler J, Elia G, et al. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci U S A. 2008 Sep 23;105:14265–14270.
   PubMed Web of Science ®Google Scholar
• Johnstone SA, Masin D, Mayer L, et al. Surface-associated serum proteins inhibit the uptake of phosphatidylserine and poly(ethylene glycol) liposomes by mouse macrophages. Biochim Biophys Acta. 2001 Jul 2;1513:25–37.
   PubMed Web of Science ®Google Scholar
• Chow T-H, Lin -Y-Y, Hwang -J-J, et al. Therapeutic efficacy evaluation of 111In-labeled PEGylated liposomal vinorelbine in murine colon carcinoma with multimodalities of molecular imaging. J Nucl Med. 2009 Dec;50:2073–2081.
   PubMed Web of Science ®Google Scholar
• Schipper ML, Iyer G, Koh AL, et al. Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice. Small. 2009 Jan;5:126–134.
   PubMed Web of Science ®Google Scholar
• Sheng Y, Yuan Y, Liu C, et al. In vitro macrophage uptake and in vivo biodistribution of PLA-PEG nanoparticles loaded with hemoglobin as blood substitutes: effect of PEG content. J Mater Sci Mater Med. 2009 Sep;20:1881–1891.
   PubMed Web of Science ®Google Scholar
• Ning YM, He K, Dagher R, et al. Liposomal doxorubicin in combination with bortezomib for relapsed or refractory multiple myeloma. Oncology (Williston Park). 2007 Nov;21:1503–1508; discussion 11, 13, 16 passim.
   PubMed Web of Science ®Google Scholar
• Hua S, Cabot PJ. Targeted nanoparticles that mimic immune cells in pain control inducing analgesic and anti-inflammatory actions: a potential novel treatment of acute and chronic pain conditions. Pain Physician. 2013 May–Jun;16:199–216.
   PubMed Web of Science ®Google Scholar
• ElBayoumi TA, Torchilin VP. Tumor-targeted nanomedicines: enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody. Clin Cancer Res. 2009 Mar 15;15:1973–1980.
   PubMed Web of Science ®Google Scholar
• Iwase Y, Maitani Y. Octreotide-targeted liposomes loaded with CPT-11 enhanced cytotoxicity for the treatment of medullary thyroid carcinoma. Mol Pharm. 2011 Mar–Apr;8:330–337.
   PubMed Web of Science ®Google Scholar
• Iwase Y, Maitani Y. Dual functional octreotide-modified liposomal irinotecan leads to high therapeutic efficacy for medullary thyroid carcinoma xenografts. Cancer Sci. 2012 Feb;103:310–316.
   PubMed Web of Science ®Google Scholar
• Ahmad I, Allen TM. Antibody-mediated specific binding and cytotoxicity of liposome-entrapped doxorubicin to lung cancer cells in vitro. Cancer Res. 1992 Sep 1;52:4817–4820.
   PubMed Web of Science ®Google Scholar
• Ahmad I, Longenecker M, Samuel J, et al. Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice. Cancer Res. 1993 Apr 1;53:1484–1488.
   PubMed Web of Science ®Google Scholar
• Maruyama K. PEG-immunoliposome. Biosci Rep. 2002 Apr;22:251–266.
   PubMed Web of Science ®Google Scholar
• Sercombe L, Veerati T, Moheimani F, et al. Advances and challenges of liposome assisted drug delivery. Front Pharmacol. 2015;6:286.
   PubMed Web of Science ®Google Scholar
• Daemen T, Hofstede G, Ten Kate MT, et al. Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages. Int J Cancer. 1995 May 29;61:716–721.
   PubMed Web of Science ®Google Scholar
• Rosenthal MS, Cullom J, Hawkins W, et al. Quantitative SPECT imaging: a review and recommendations by the focus committee of the society of nuclear medicine computer and instrumentation council. J Nucl Med. 1995 Aug;36:1489–1513.
   PubMed Web of Science ®Google Scholar
• Van Der Have F, Vastenhouw B, Ramakers RM, et al. U-SPECT-II: an ultra-high-resolution device for molecular small-animal imaging. J Nucl Med. 2009 Apr;50:599–605.
   PubMed Web of Science ®Google Scholar
• Lee SY, Jeon SI, Jung S, et al. Targeted multimodal imaging modalities. Adv Drug Deliv Rev. 2014 Sep 30;76:60–78.
   PubMed Web of Science ®Google Scholar
• Allen TM, Hansen C. Pharmacokinetics of stealth versus conventional liposomes: effect of dose. Biochim Biophys Acta. 1991 Sep 30;1068:133–141.
   PubMed Web of Science ®Google Scholar
• Unezaki S, Maruyama K, Takahashi N, et al. Enhanced delivery and antitumor activity of doxorubicin using long-circulating thermosensitive liposomes containing amphipathic polyethylene glycol in combination with local hyperthermia. Pharm Res. 1994 Aug;11:1180–1185.
   PubMed Web of Science ®Google Scholar
• Srivatsan A, Chen X. Recent advances in nanoparticle-based nuclear imaging of cancers. Adv Cancer Res. 2014;124:83–129.
   PubMed Web of Science ®Google Scholar
• McDougall IR, Dunnick JK, Goris ML, et al. In vivo distribution of vesicles loaded with radiopharmaceuticals: a study of different routes of administration. J Nucl Med. 1975 Jun;16:488–491.
   PubMed Web of Science ®Google Scholar
• Caride VJ. Technical and biological considerations on the use of radiolabeled liposomes for diagnostic imaging. Int J Rad Appl Instrum B. 1990;17:35–39.
   PubMedGoogle Scholar
• McDougall IR, Dunnick JK, Goris ML, et al. In vivo distribution of vesicles loaded with radiopharmaceuticals: a comparison of different routes of administration. Scott Med J. 1975 Jan;20:39.
   PubMed Web of Science ®Google Scholar
• Oku N, Tokudome Y, Tsukada H, et al. In vivo trafficking of long-circulating liposomes in tumour-bearing mice determined by positron emission tomography. Biopharm Drug Dispos. 1996 Jul;17:435–441.
   PubMed Web of Science ®Google Scholar
• Marik J, Tartis MS, Zhang H, et al. Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP). Nucl Med Biol. 2007 Feb;34:165–171.
   PubMed Web of Science ®Google Scholar
• Caride VJ, Taylor W, Cramer JA, et al. Evaluation of liposome-entrapped radioactive tracers as scanning agents. Part 1: organ distribution of liposome (99mTc-DTPA) in mice. J Nucl Med. 1976 Dec;17:1067–1072.
   PubMed Web of Science ®Google Scholar
• Henriksen JR, Petersen AL, Hansen AE, et al. Remote loading of (64)Cu(2+) into liposomes without the use of ion transport enhancers. ACS Appl Mater Interfaces. 2015 Oct 21;7:22796–22806.
   PubMed Web of Science ®Google Scholar
• Mauk MR, Gamble RC. Preparation of lipid vesicles containing high levels of entrapped radioactive cations. Anal Biochem. 1979 Apr 15;94:302–307.
   PubMed Web of Science ®Google Scholar
• Beaumier PL, Hwang KJ. An efficient method for loading indium-111 into liposomes using acetylacetone. J Nucl Med. 1982 Sep;23:810–815.
   PubMed Web of Science ®Google Scholar
• Tilcock C, Yap M, Szucs M, et al. PEG-coated lipid vesicles with encapsulated technetium-99m as blood pool agents for nuclear medicine. Nucl Med Biol. 1994 Feb;21:165–170.
   PubMed Web of Science ®Google Scholar
• Chang M-Y, Seideman J, Sofou S. Enhanced loading efficiency and retention of 225Ac in rigid liposomes for potential targeted therapy of micrometastases. Bioconjug Chem. 2008 Jun;19:1274–1282.
   PubMed Web of Science ®Google Scholar
• Gabizon A, Papahadjopoulos D. Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors. P Natl Acad Sci USA. 1988 Sep;85:6949–6953.
   PubMed Web of Science ®Google Scholar
• van der Geest T, Laverman P, Gerrits D, et al. Comparison of three remote radiolabelling methods for long-circulating liposomes. J Control Release. 2015 Dec 28;220:239–244.
   PubMed Web of Science ®Google Scholar
• Woodle MC. Gallium-67-labeled liposomes with prolonged circulation - preparation and potential as nuclear imaging agents. Nucl Med Biol. 1993 Feb;20:149–155.
   PubMed Web of Science ®Google Scholar
• Bao A, Goins B, Klipper R, et al. A novel liposome radiolabeling method using 99mTc-“SNS/S” complexes: in vitro and in vivo evaluation. J Pharm Sci. 2003 Sep;92:1893–1904.
   PubMed Web of Science ®Google Scholar
• Dams ET, Oyen WJ, Boerman OC, et al. Technetium-99m-labeled PEG-liposomes for the detection of infection and inflammation. J Nucl Med. 1999 May;40:15p–15p.
   Web of Science ®Google Scholar
• Bao A, Goins B, Klipper R, et al. 186Re-liposome labeling using 186Re-SNS/S complexes: in vitro stability, imaging, and biodistribution in rats. J Nucl Med. 2003 Dec;44:1992–1999.
   PubMed Web of Science ®Google Scholar
• Phillips WT, Goins B, Bao A, et al. Rhenium-186 liposomes as convection-enhanced nanoparticle brachytherapy for treatment of glioblastoma. Neuro Oncol. 2012 Apr;14:416–425.
   PubMed Web of Science ®Google Scholar
• Chen L-C, Chang C-H, Yu C-Y, et al. Biodistribution, pharmacokinetics and imaging of (188)Re-BMEDA-labeled pegylated liposomes after intraperitoneal injection in a C26 colon carcinoma ascites mouse model. Nucl Med Biol. 2007 May;34:415–423.
   PubMed Web of Science ®Google Scholar
• Petersen AL, Binderup T, Rasmussen P, et al. 64Cu loaded liposomes as positron emission tomography imaging agents. Biomaterials. 2011 Mar;32:2334–2341.
   PubMed Web of Science ®Google Scholar
• Seo JW, Zhang H, Kukis DL, et al. A novel method to label preformed liposomes with 64Cu for positron emission tomography (PET) imaging. Bioconjug Chem. 2008 Dec;19:2577–2584.
   PubMed Web of Science ®Google Scholar
• Lingappa M, Song H, Thompson S, et al. Immunoliposomal delivery of 213Bi for alpha-emitter targeting of metastatic breast cancer. Cancer Res. 2010 Sep 1;70:6815–6823.
   PubMed Web of Science ®Google Scholar
• Laverman P, Dams ETM, Oyen WJG, et al. A novel method to label liposomes with 99mTc by the hydrazino nicotinyl derivative. J Nucl Med. 1999 Jan;40:192–197.
   PubMed Web of Science ®Google Scholar
• Goins B, Bao A, Phillips WT. Techniques for loading technetium-99m and rhenium-186/188 radionuclides into pre-formed liposomes for diagnostic imaging and radionuclide therapy. Methods Mol Biol. 2010;606:469–491.
   PubMedGoogle Scholar
• Dams ET, Oyen WJ, Boerman OC, et al. 99mTc-PEG liposomes for the scintigraphic detection of infection and inflammation: clinical evaluation. J Nucl Med. 2000 Apr;41:622–630.
   PubMed Web of Science ®Google Scholar
• Boerman OC, Laverman P, Oyen WJG, et al. Radiolabeled liposomes for scintigraphic imaging. Prog Lipid Res. 2000 Sep;39:461–475.
   PubMed Web of Science ®Google Scholar
• Ogawa M, Uchino R, Kawai A, et al. PEG modification on (111)In-labeled phosphatidyl serine liposomes for imaging of atherosclerotic plaques. Nucl Med Biol. 2015 Mar;42:299–304.
   PubMed Web of Science ®Google Scholar
• Lin YY, Kao HW, Li JJ, et al. Tumor burden talks in cancer treatment with PEGylated liposomal drugs. PLoS One. 2013;8:e63078.
   PubMed Web of Science ®Google Scholar
• Ogawa M, Umeda IO, Kosugi M, et al. Development of 111In-labeled liposomes for vulnerable atherosclerotic plaque imaging. J Nucl Med. 2014 Jan;55:115–120.
   PubMed Web of Science ®Google Scholar
• Turker S, Erdogan S, Ozer AY, et al. Scintigraphic imaging of radiolabelled drug delivery systems in rabbits with arthritis. Int J Pharm. 2005 May 30;296:34–43.
   PubMed Web of Science ®Google Scholar
• Moghimi SM, Szebeni J. Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog Lipid Res. 2003 Nov;42:463–478.
   PubMed Web of Science ®Google Scholar
• Jensen GM, Bunch TH. Conventional liposome performance and evaluation: lessons from the development of Vescan. J Liposome Res. 2007;17:121–137. .
   PubMed Web of Science ®Google Scholar
• Presant CA, Turner AF, Profitt RT. Potential for improvement in clinical decision-making: tumor imaging with in-111 labeled liposomes results of a phase ii-iii study. J Liposome Res. 1994 Jan;4:985–1008.
   Google Scholar
• Khalifa A, Dodds D, Rampling R, et al. Liposomal distribution in malignant glioma: possibilities for therapy. Nucl Med Commun. 1997 Jan;18:17–23.
   PubMed Web of Science ®Google Scholar
• Kubo A, Nakamura K, Sammiya T, et al. Indium-111-labelled liposomes: dosimetry and tumour detection in patients with cancer. Eur J Nucl Med. 1993 Feb;20:107–113.
   PubMedGoogle Scholar
• Harrington KJ, Mohammadtaghi S, Uster PS, et al. Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes. Clin Cancer Res. 2001 Feb;7:243–254.
   PubMed Web of Science ®Google Scholar
• Morgan JR, Williams LA, Howard CB. Technetium-labelled liposome imaging for deep-seated infection. Brit J Radiol. 1985;58:35–39.
   PubMed Web of Science ®Google Scholar
• Boerman OC, Oyen WJ, Storm G, et al. Technetium-99m labelled liposomes to image experimental arthritis. Ann Rheum Dis. 1997 Jun;56:369–373.
   PubMed Web of Science ®Google Scholar
• Metselaar JM, Storm G. Liposomes in the treatment of inflammatory disorders. Expert Opin Drug Deliv. 2005 May;2:465–476.
   PubMedGoogle Scholar
• Metselaar JM, Van Den Berg WB, Holthuysen AE, et al. Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis. Ann Rheum Dis. 2004 Apr;63:348–353.
   PubMed Web of Science ®Google Scholar
• Ozbakir B, Crielaard BJ, Metselaar JM, et al. Liposomal corticosteroids for the treatment of inflammatory disorders and cancer. J Control Release. 2014 Sep 28;190:624–636.
   PubMed Web of Science ®Google Scholar
• Laverman L, Boerman B, Oyen O, et al. Liposomes for scintigraphic detection of infection and inflammation. Adv Drug Deliv Rev. 1999 May 4;37:225–235.
   PubMed Web of Science ®Google Scholar
• Laverman P, Brouwers AH, Dams ET, et al. Preclinical and clinical evidence for disappearance of long-circulating characteristics of polyethylene glycol liposomes at low lipid dose. J Pharmacol Exp Ther. 2000 Jun;293:996–1001.
   PubMed Web of Science ®Google Scholar
• Emmetiere F, Irwin C, Viola-Villegas NT, et al. (18)F-labeled-bioorthogonal liposomes for in vivo targeting. Bioconjug Chem. 2013 Nov 20;24:1784–1789.
   PubMed Web of Science ®Google Scholar
• Jensen ATI, Binderup T, Andresen TL, et al. PET imaging of liposomes labeled with an [¹⁸F]-fluorocholesteryl ether probe prepared by automated radiosynthesis. J Liposome Res. 2012 Dec;22:295–305.
   PubMed Web of Science ®Google Scholar
• Helbok A, Decristoforo C, Dobrozemsky G, et al. Radiolabeling of lipid-based nanoparticles for diagnostics and therapeutic applications: a comparison using different radiometals. J Liposome Res. 2010 Sep;20:219–227.
   PubMed Web of Science ®Google Scholar
• Locke LW, Mayo MW, Yoo AD, et al. PET imaging of tumor associated macrophages using mannose coated 64Cu liposomes. Biomaterials. 2012 Nov;33:7785–7793.
   PubMed Web of Science ®Google Scholar
• Petersen AL, Henriksen JR, Binderup T, et al. In vivo evaluation of PEGylated (64)Cu-liposomes with theranostic and radiotherapeutic potential using micro PET/CT. Eur J Nucl Med Mol Imaging. 2016 May;43:941–952.
   PubMed Web of Science ®Google Scholar
• Abou DS, Thorek DLJ, Ramos NN, et al. (89)Zr-labeled paramagnetic octreotide-liposomes for PET-MR imaging of cancer. Pharm Res. 2013 Mar;30:878–888.
   PubMed Web of Science ®Google Scholar
• Chow T-H, Lin -Y-Y, Hwang -J-J, et al. Diagnostic and therapeutic evaluation of 111In-vinorelbine-liposomes in a human colorectal carcinoma HT-29/luc-bearing animal model. Nucl Med Biol. 2008 Jul;35:623–634.
   PubMed Web of Science ®Google Scholar
• Koukourakis MI, Koukouraki S, Fezoulidis I, et al. High intratumoural accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumours. Br J Cancer. 2000 Nov;83:1281–1286.
   PubMed Web of Science ®Google Scholar
• Laverman P, Boerman OC, Storm G, et al. (99m)Tc-labelled stealth liposomal doxorubicin (Caelyx) in glioblastomas and metastatic brain tumours. Br J Cancer. 2002 Feb 12;86:659–661.
   PubMed Web of Science ®Google Scholar
• Lin L-T, Chang C-H, Yu H-L, et al. Evaluation of the therapeutic and diagnostic effects of PEGylated liposome-embedded 188Re on human non-small cell lung cancer using an orthotopic small-animal model. J Nucl Med. 2014 Nov;55:1864–1870.
   PubMed Web of Science ®Google Scholar
• MacKay JA, Deen DF, Szoka FC Jr. Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating. Brain Res. 2005 Feb 28;1035:139–153.
   PubMed Web of Science ®Google Scholar
• Soundararajan A, Bao A, Phillips WT, et al. [(186)Re]Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model. Nucl Med Biol. 2009 Jul;36:515–524.
   PubMed Web of Science ®Google Scholar
• Phillips WT, Bao A, Brenner AJ, et al. Image-guided interventional therapy for cancer with radiotherapeutic nanoparticles. Adv Drug Deliv Rev. 2014 Sep 30;76:39–59.
   PubMed Web of Science ®Google Scholar
• Dawidczyk CM, Kim C, Park JH, et al. State-of-the-art in design rules for drug delivery platforms: lessons learned from FDA-approved nanomedicines. J Control Release. 2014 Aug 10;187:133–144.
   PubMed Web of Science ®Google Scholar
• Chamberlain MC. Neurotoxicity of intra-CSF liposomal cytarabine (DepoCyt) administered for the treatment of leptomeningeal metastases: a retrospective case series. J Neurooncol. 2012 Aug;109:143–148.
   PubMed Web of Science ®Google Scholar
• Barratt G, Legrand P. Comparison of the efficacy and pharmacology of formulations of amphotericin B used in treatment of leishmaniasis. Curr Opin Infect Dis. 2005 Dec;18:527–530.
   PubMed Web of Science ®Google Scholar
• Gabizon A, Shmeeda H, Barenholz Y. Pharmacokinetics of pegylated liposomal doxorubicin: review of animal and human studies. Clin Pharmacokinet. 2003;42:419–436.
   PubMed Web of Science ®Google Scholar