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Review

Elastin-like polypeptides: the power of design for smart cell encapsulation

Pages 37-48 | Received 29 Mar 2016, Accepted 22 Jun 2016, Published online: 14 Jul 2016

References

  • Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science. 1980;210(4472):908–910.
  • Hunt NC, Grover LM. Cell encapsulation using biopolymer gels for regenerative medicine. Biotechnol Lett. 2010;32(6):733–742.
  • Hashemi M, Kalalinia F. Application of encapsulation technology in stem cell therapy. Life Sci. 2015;143:139–146.
  • Orive G, Santos E, Poncelet D, et al. Cell encapsulation: technical and clinical advances. Trends Pharmacol Sci. 2015;36(8):537–546.
  • Kang HW, Lee SJ, Ko IK, et al. A 3D bioprinting system to produce human-scale tissue constructs with structural integrity. Nat Biotechnol. 2016;34(3):312–319.
  • Nicodemus GD, Bryant SJ. Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Eng Part B Rev. 2008;14(2):149–165.
  • Gasperini L, Mano JF, Reis RL. Natural polymers for the microencapsulation of cells. J R Soc Interface. 2014;11(100):20140817.
  • Chen W, Tabata Y, Tong YW. Fabricating tissue engineering scaffolds for simultaneous cell growth and drug delivery. Curr Pharm Des. 2010;16(21):2388–2394.
  • Ayres CE, Jha BS, Sell SA, et al. Nanotechnology in the design of soft tissue scaffolds: innovations in structure and function. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;2(1):20–34.
  • Hinderer S, Layland SL, Schenke-Layland K. ECM and ECM-like materials - Biomaterials for applications in regenerative medicine and cancer therapy. Adv Drug Deliv Rev. 2016;97:260–269.
  • Ladewig K. Drug delivery in soft tissue engineering. Expert Opin Drug Deliv. 2011;8(9):1175–1188.
  • Kharkar PM, Kiick KL, Kloxin AM. Designing degradable hydrogels for orthogonal control of cell microenvironments. Chem Soc Rev. 2013;42(17):7335–7372.
  • Urry DW, Long MM, Cox BA, et al. The synthetic polypentapeptide of elastin coacervates and forms filamentous aggregates. Biochim Biophys Acta. 1974;371(2):597–602.
  • Urry DW. Physical chemistry of biological free energy transduction as demonstrated by elastic protein-based polymers. J Phys Chem B. 1997;101:11007–11028.
  • McPherson DT, Morrow C, Minehan DS, et al. Production and purification of a recombinant elastomeric polypeptide, G-(VPGVG)19-VPGV, from Escherichia coli. Biotechnol Prog. 1992;8(4):347–352.
  • Chilkoti A, Dreher MR, Meyer DE. Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery. Adv Drug Deliv Rev. 2002;54(8):1093–1111.
  • Rodríguez-Cabello JC, Pierna M, Fernández-Colino A, et al. Recombinamers: combining molecular complexity with diverse bioactivities for advanced biomedical and biotechnological applications. Adv Biochem Eng Biotechnol. 2011;125:145–179.
  • Van Eldijk MB, McGann CL, Kiick KL, et al. Elastomeric polypeptides. Top Curr Chem. 2012;310:71–116.
  • MacEwan SR, Chilkoti A. Elastin-like polypeptides: biomedical applications of tunable biopolymers. Biopolymers. 2010;94(1):60–77.
  • Rodríguez-Cabello JC, Martín L, Girotti A, et al. Emerging applications of multifunctional elastin-like recombinamers. Nanomedicine (Lond). 2011;6(1):111–122.
  • Shang Y, Yan Y, Hou X. Stimuli responsive elastin-like polypeptides and applications in medicine and biotechnology. J Biomater Sci Polym Ed. 2014;25(2):101–120.
  • Bidwell GL, Raucher D 3rd. Cell penetrating elastin-like polypeptides for therapeutic peptide delivery. Adv Drug Deliv Rev. 2010;62(15):1486–1496.
  • Altunbas A, Pochan DJ. Peptide-based and polypeptide-based hydrogels for drug delivery and tissue engineering. Top Curr Chem. 2012;310:135–167.
  • Frandsen JL, Ghandehari H. Recombinant protein-based polymers for advanced drug delivery. Chem Soc Rev. 2012;41(7):2696–2706.
  • Johnson NR, Wang Y. Coacervate delivery systems for proteins and small molecule drugs. Expert Opin Drug Deliv. 2014;11(12):1829–1832.
  • Rodríguez-Cabello JC, Arias FJ, Rodrigo MA, et al. Elastin-like polypeptides in drug delivery. Adv Drug Deliv Rev. 2016;97:85–100.
  • Wright ER, Conticello VP. Self-assembly of block copolymers derived from elastin-mimetic polypeptide sequences. Adv Drug Deliv Rev. 2002;54(8):1057–1073.
  • Rodríguez-Cabello JC, Piña MJ, Ibáñez-Fonseca A, et al. Nanotechnological approaches to therapeutic delivery using elastin-like recombinamers. Bioconjug Chem. 2015;26(7):1252–1265.
  • Banta S, Wheeldon IR, Blenner M. Protein engineering in the development of functional hydrogels. Annu Rev Biomed Eng. 2010;12:167–186.
  • Nagaoka M, Jiang HL, Hoshiba T, et al. Application of recombinant fusion proteins for tissue engineering. Ann Biomed Eng. 2010;38(3):683–693.
  • Nettles DL, Chilkoti A, Setton LA. Applications of elastin-like polypeptides in tissue engineering. Adv Drug Deliv Rev. 2010;62(15):1479–1485.
  • Desai MS, Lee SW. Protein-based functional nanomaterial design for bioengineering applications. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015;7(1):69–97.
  • Urry DW, Parker TM, Reid MC, et al. Biocompatibility of the bioelastic materials, poly(GVGVP) and its gamma-irradiation cross-linked matrix – summary of generic biological test results. J Bioact Compat Polym. 1991;6:263–282.
  • Mackay JA, Chilkoti A. Temperature sensitive peptides: engineering hyperthermia-directed therapeutics. Int J Hyperthermia. 2008;24(6):483–495.
  • Nouri FS, Wang X, Chen X, et al. Reducing the visibility of the vector/DNA nanocomplexes to the immune system by elastin-like peptides. Pharm Res. 2015;32(9):3018–3028.
  • Betre H, Setton LA, Meyer DE, et al. Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair. Biomacromolecules. 2002;3(5):910–916.
  • Betre H, Ong SR, Guilak F, et al. Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. Biomaterials. 2006;27(1):91–99.
  • McHale MK, Setton LA, Chilkoti A. Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair. Tissue Eng. 2005;11(11–12):1768–1779.
  • Lim DW, Nettles DL, Setton LA, et al. Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. Biomacromolecules. 2007;8(5):1463–1470.
  • Lim DW, Nettles DL, Setton LA, et al. In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair. Biomacromolecules. 2008;9(1):222–230.
  • Wheeler TS, Sbravati ND, Janorkar AV. Mechanical & and cell culture properties of elastin-like polypeptide, collagen, bioglass, and carbon nanosphere composites. Ann Biomed Eng. 2013;41(10):2042–2055.
  • McDaniel JR, Dewhirst MW, Chilkoti A. Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia. Int J Hyperthermia. 2013;29(6):501–510.
  • Nettles DL, Chilkoti A, Setton LA. Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds. Tissue Eng Part A. 2009;15(8):2113–2121.
  • Megeed Z, Cappello J, Ghandehari H. Genetically engineered silk-elastinlike protein polymers for controlled drug delivery. Adv Drug Deliv Rev. 2002;54(8):1075–1091.
  • Haider M, Cappello J, Ghandehari H, et al. In vitro chondrogenesis of mesenchymal stem cells in recombinant silk-elastin like hydrogels. Pharm Res. 2008;25(3):692–699.
  • Testera AM, Girotti A, De Torre IG, et al. Biocompatible elastin-like click gels: design, synthesis and characterization. J Mater Sci Mater Med. 2015;26(2):105–117.
  • Straley KS, Heilshorn SC. Independent tuning of multiple biomaterial properties using protein engineering. Soft Matter. 2009;5:114–124.
  • Sun F, Zhang WB, Mahdavi A, et al. Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry. Proc Natl Acad Sci U S A. 2014;111(31):11269–11274.
  • Zhang WB, Sun F, Tirrell DA, et al. Controlling macromolecular topology with genetically encoded SpyTag-SpyCatcher chemistry. J Am Chem Soc. 2013;135(37):13988–13997.
  • Glassman MJ, Avery RK, Khademhosseini A, et al. Toughening of thermoresponsive arrested networks of elastin-like polypeptides to engineer cytocompatible tissue scaffolds. Biomacromolecules. 2016;17(2):415–426.
  • Martín L, Alonso M, Girotti A, et al. and characterization of macroporous thermosensitive hydrogels from recombinant elastin-like polymers. Biomacromolecules. 2009;10(11):3015–3322.
  • Fernández-Colino A, Arias FJ, Alonso M, et al. ECM-mimetic model based on an amphiphilic multiblock silk-elastin-like corecombinamer with a concomitant dual physical gelation process. Biomacromolecules. 2014;15(10):3781–3793.
  • Fernández-Colino A, Arias FJ, Alonso M, et al. Amphiphilic elastin-like block co-recombinamers containing Leucine Zippers: cooperative interplay between both domains results in injectable and stable hydrogels. Biomacromolecules. 2015;16(10):3389–3398.
  • Sánchez-Ferrero A, Mata Á, Mateos-Timoneda MA, et al. Development of tailored and self-mineralizing citric acid-crosslinked hydrogels for in situ bone regeneration. Biomaterials. 2015;68:42–53.
  • Chung C, Lampe KJ, Heilshorn SC. Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels. Biomacromolecules. 2012;13(12):3912–3916.
  • Chung C, Anderson E, Pera RR, et al. Hydrogel crosslinking density regulates temporal contractility of human embryonic stem cell-derived cardiomyocytes in 3D cultures. Soft Matter. 2012;8(39):10141–10148.
  • Chung C, Pruitt BL, Heilshorn SC. Spontaneous cardiomyocyte differentiation of mouse embryoid bodies regulated by hydrogel crosslink density. Biomater Sci. 2013;1(10):1082–1090.
  • Chang DT, Chai R, DiMarco R, et al. Protein-engineered hydrogel encapsulation for 3-D culture of murine cochlea. Otol Neurotol. 2015;36(3):531–538.
  • Lampe KJ, Antaris AL, Heilshorn SC. Design of three-dimensional engineered protein hydrogels for tailored control of neurite growth. Acta Biomater. 2013;9(3):5590–5599.
  • DiMarco RL, Dewi RE, Bernal G, et al. Protein-engineered scaffolds for in vitro 3D culture of primary adult intestinal organoids. Biomater Sci. 2015;3(10):1376–1385.
  • Cai L, Dinh CB, Heilshorn SC. One-pot synthesis of elastin-like polypeptide hydrogels with grafted VEGF-mimetic peptides. Biomater Sci. 2014;2(5):757–765.
  • Glassman MJ, Olsen BD. Arrested phase separation of elastin-like polypeptide solutions yields stiff, thermoresponsive gels. Biomacromolecules. 2015;16(12):3762–3773.
  • Rapaka RS, Okamoto K, Urry DW. Non-elastomeric polypeptide models of elastin. Synthesis of polyhexapeptides and a cross-linked polyhexapeptide. Int J Pept Protein Res. 1978;11(2):109–127.
  • Bellingham CM, Woodhouse KA, Robson P, et al. Self-aggregation characteristics of recombinantly expressed human elastin polypeptides. Biochim Biophys Acta. 2001;1550(1):6–19.
  • Bandiera A. Assembly and optimization of expression of synthetic genes derived from the human elastin repeated motif. Prep Biochem Biotechnol. 2010;40(3):198–212.
  • Bandiera A. Transglutaminase-catalyzed preparation of human elastin-like polypeptide-based three-dimensional matrices for cell encapsulation. Enzyme Microb Technol. 2011;49(4):347–352.
  • Bellingham CM, Lillie MA, Gosline JM, et al. Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties. Biopolymers. 2003;70(4):445–455.
  • Moss IL, Gordon L, Woodhouse KA, et al. A novel thiol-modified hyaluronan and elastin-like polypeptide composite material for tissue engineering of the nucleus pulposus of the intervertebral disc. Spine (Phila Pa 1976). 2011;36(13):1022–1029.
  • Leckie AE, Akens MK, Woodhouse KA, et al. Evaluation of thiol-modified hyaluronan and elastin-like polypeptide composite augmentation in early-stage disc degeneration: comparing 2 minimally invasive techniques. Spine (Phila Pa 1976). 2012;37(20):E1296–E1303.
  • Luan CH, Parker TM, Prasad KU, et al. Differential scanning calorimetry studies of NaCl effect on the inverse temperature transition of some elastin-based polytetra-, polypenta-, and polynonapeptides. Biopolymers. 1991;31(5):465–475.
  • Bandiera A, Markulin A, Corich L, et al. Stimuli-induced release of compounds from elastin biomimetic matrix. Biomacromolecules. 2014;15(1):416–422.

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