181
Views
8
CrossRef citations to date
0
Altmetric
Original Research

Evaluating the safety of phytosterols removed perilla seed oil-based lipid emulsion

, , , , , , , & show all
Pages 1345-1356 | Received 11 Mar 2016, Accepted 12 Jul 2016, Published online: 29 Jul 2016

References

  • Guglielmi F, Boggio-Bertinet D, Federico A, et al. Total parenteral nutrition-related gastroenterological complications. Digestive Liver Dis. 2006;38(9):623–642.
  • Calder PC, Jensen GL, Koletzko BV, et al. Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions. Intensive Care Med. 2010;36(5):735–749.
  • Fell GL, Nandivada P, Gura KM, et al. Intravenous lipid emulsions in parenteral nutrition. Adv Nutr: Int Rev J. 2015;6(5):600–610.
  • Chawla D, Thukral A, Agarwal R, et al. Parenteral nutrition. Ind J Pediatr. 2008;75(4):377–383.
  • Vanek VW, Seidner DL, Allen P, et al. ASPEN position paper: clinical role for alternative intravenous fat emulsions. Nutr Clin Pract. 2012;27:150–192. doi:10.1177/0884533612439896.
  • Wanten GJA, Calder PC. Immune modulation by parenteral lipid emulsions. Am J Clin Nutr. 2007;85(5):1171–1184.
  • Bharadwaj S, Gohel T, Deen OJ, et al. Fish oil-based lipid emulsion: current updates on a promising novel therapy for the management of parenteral nutrition-associated liver disease. Gastroenterol Rep. 2015;3:110–114. gov011
  • Waitzberg DL, Torrinhas RS, Jacintho TM. New parenteral lipid emulsions for clinical use. J Parenteral Enteral Nutr. 2006;30(4):351–367.
  • Adolph M. Lipid emulsions in total parenteral nutrition and future perspectives. Clin Nutr. 2001;20(4):11–14.
  • Driscoll DF, Bistrian BR, Demmelmair H, et al. Pharmaceutical and clinical aspects of parenteral lipid emulsions in neonatology. Clin Nutr. 2008;27(4):497–503.
  • Pontes-Arruda A. Biological benefits of an oleic acid–rich lipid emulsion for parenteral nutrition. Clin Nutr Suppl. 2009;4(1):19–23.
  • De Nardi L, Bellinati-Pires R, Torrinhas RS, et al. Effect of fish oil containing parenteral lipid emulsions on neutrophil chemotaxis and resident-macrophages’ phagocytosis in rats. Clin Nutr. 2008;27(2):283–288.
  • Kurowska EM, Dresser GK, Deutsch L, et al. Bioavailability of omega-3 essential fatty acids from perilla seed oil. Prostaglandins Leukotrienes Essent Fatty Acids. 2003;68(3):207–212.
  • Talbott SM, Hughes K. Perilla seed oil (Perilla frutescens). The health professional’s guide to dietary supplements. Baltimore, MD: Lippincott Williams & Wilkins; 2006. p. 258–260.
  • Žekonis G, Žekonis J, Šadzeviciene R, et al. Effect of Perilla frutescens aqueous extract on free radical production by human neutrophil leukocytes. Medicina (Kaunas). 2008;44(9):9.
  • Asif M. Health effects of omega-3, 6, 9 fatty acids: perilla frutescens is a good example of plant oils. Orient Pharm Exp Med. 2011;11(1):51–59.
  • Chang H-H, Chen C-S, Lin J-Y. Dietary perilla oil lowers serum lipids and ovalbumin-specific IgG1, but increases total IgE levels in ovalbumin-challenged mice. Food Chem Toxicol. 2009;47(4):848–854.
  • Ihara-Watanabe M, Umekawa H, Takahashi T, et al. Comparative effects of safflower oil and perilla oil on serum and hepatic lipid levels, fatty acid compositions of serum and hepatic phospholipids, and hepatic mRNA expressions of 3-hydroxy-3-methylglutaryl CoA reductase, LDL receptor, and cholesterol 7alpha-hydroxylase in young and adult rats. Food Res Int. 2000;33(10):893–900.
  • Chang Y-F, Hou Y-C, Pai M-H, et al. Effects of ω-3 polyunsaturated fatty acids on the homeostasis of CD4+ T cells and lung injury in mice with polymicrobial sepsis. J Parenteral Enteral Nutr. 2015. doi:10.1177/0148607115597670.
  • Ren T, Cong L, Wang Y, et al. Lipid emulsions in parenteral nutrition: current applications and future developments. Expert Opin Drug Deliv. 2013;10(11):1533–1549.
  • Hallberg D. Studies on the elimination of exogenous lipids from the blood stream the kinetics of the elimination of a fat emulsion studied by single injection technique in man. Acta Physiol Scand. 1965;64(4):306–313.
  • Hallberg D, Holm I, Obel AL, et al. Fat emulsions for complete intravenous nutrition. Postgrad Med J. 1967;43(498):307.
  • Calkins KL, Havranek T, Kelley-Quon LI, et al. Low-dose parenteral soybean oil for the prevention of parenteral nutrition–associated liver disease in neonates with gastrointestinal disorders a multicenter randomized controlled pilot study. J Parenteral Enteral Nutr. 2015. doi:10.1177/0148607115588334.
  • Clayton PT, Whitfield P, Iyer K. The role of phytosterols in the pathogenesis of liver complications of pediatric parenteral nutrition. Nutrition. 1998;14(1):158–164.
  • Iyer KR, Spitz L, Clayton P. New insight into mechanisms of parenteral nutrition—associated cholestasis: role of plant sterols. J Pediatr Surg. 1998;33(1):1–6.
  • Cober MP, Killu G, Brattain A, et al. Intravenous fat emulsions reduction for patients with parenteral nutrition–associated liver disease. J Pediatr. 2012;160(3):421–427.
  • El Kasmi KC, Anderson AL, Devereaux MW, et al. Phytosterols promote liver injury and Kupffer cell activation in parenteral nutrition–associated liver disease. Sci Transl Med. 2013;5(206):206ra137–206ra137.
  • Puder M, Valim C, Meisel JA, et al. Parenteral fish oil improves outcomes in patients with parenteral nutrition associated liver injury. Ann Surg. 2009;250(3):395.
  • Lee WS, Sokol RJ. Intestinal microbiota, lipids, and the pathogenesis of intestinal failure–associated liver disease. J Pediatr. 2015;167:519–526.
  • Zaloga GP. Phytosterols, lipid administration, and liver disease during parenteral nutrition. J Parenteral Enteral Nutr. 2015;39:39S–60S. doi:10.1177/0148607115595978.
  • Xu Z, Harvey KA, Pavlina T, et al. Steroidal compounds in commercial parenteral lipid emulsions. Nutrients. 2012;4(8):904–921.
  • Kurvinen A, Nissinen MJ, Andersson S, et al. Parenteral plant sterols and intestinal failure–associated liver disease in neonates. J Pediatr Gastroenterol Nutr. 2012;54(6):803–811.
  • Forchielli ML, Bersani G, Tala S, et al. The spectrum of plant and animal sterols in different oil-derived intravenous emulsions. Lipids. 2010;45(1):63–71.
  • Sanchez SE, Braun LP, Mercer LD, et al. The effect of lipid restriction on the prevention of parenteral nutrition-associated cholestasis in surgical infants. J Pediatr Surg. 2013;48(3):573–578.
  • Angsten G, Finkel Y, Lucas S, et al. Improved outcome in neonatal short bowel syndrome using parenteral fish oil in combination with ω-6/9 lipid emulsions. J Parenteral Enteral Nutr. 2012;36(5):587–595.
  • Khan FA, Fisher JG, Sparks EA, et al. Preservation of biochemical liver function with low-dose soy-based lipids in children with intestinal failure–associated liver disease. J Pediatr Gastroenterol Nutr. 2015;60(3):375–377.
  • Verleyen T, Sosinska U, Ioannidou S, et al. Influence of the vegetable oil refining process on free and esterified sterols. J Am Oil Chem Soc. 2002;79(10):947–953.
  • Ostlund RE, Racette SB, Okeke A, et al. Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans. Am J Clin Nutr. 2002;75(6):1000–1004.
  • Wiedermann LH. Degumming, refining and bleaching soybean oil. J Am Oil Chem Soc. 1981;58(3):159–166.
  • Helme J-P. Soybean oil refining. Rapport Tech. Am. Soybean Assoc. 1984;70:150.
  • Edgren B, Hallberg D, Hakansson I, et al. Long-term tolerance study of two fat emulsions for intravenous nutrition in dogs. Am J Clin Nutr. 1964;14(1):28–36.
  • Cao J, Schwichtenberg KA, Hanson NQ, et al. Incorporation and clearance of omega-3 fatty acids in erythrocyte membranes and plasma phospholipids. Clin Chem. 2006;52(12):2265–2272.
  • Cohen C, Olsen MM. Pediatric total parenteral nutrition. Liver histopathology. Arch Pathol Lab Med. 1981;105(3):152–156.
  • Reimold EW. Studies of the toxicity of an intravenous fat emulsion. II. Blood chemical changes after administration of a soybean oil (FE-S15) in beagles. J Parenteral Enteral Nutr. 1979;3(5):335–340.
  • Håkansson I. Experience in long-term studies on nine intravenous fat emulsions in dogs. Ann Nutr Metabolism. 1968;10(1):54–76.
  • Bernabe-Garcia M, Lopez-Alarcón M, Blanco-Favela F, et al. Beneficial effects of the n-3 long-chain polyunsaturated fatty acids in surgical patients: updating the evidence. Prostaglandins Leukotrienes Essent Fatty Acids (PLEFA). 2011;85(5):261–266.
  • Tabas I. Consequences of cellular cholesterol accumulation: basic concepts and physiological implications. J Clin Investig. 2002;110(7):905–912.
  • Saubion JL, Hazane C, Jalabert M. The role of sterols in lipid emulsions for parenteral nutrition. Nutrition. 1998;14(5):477–478.
  • Carter BA, Taylor OA, Prendergast DR, et al. Stigmasterol, a soy lipid–derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR. Pediatr Res. 2007;62(3):301–306.
  • Zimmerman TL, Thevananther S, Ghose R, et al. Nuclear export of retinoid X receptor α in response to interleukin-1β-mediated cell signaling ROLES FOR JNK AND SER260. J Biol Chem. 2006;281(22):15434–15440.
  • Diamond IR, De Silva NT, Tomlinson GA, et al. The role of parenteral lipids in the development of advanced intestinal failure–associated liver disease in infants a multiple-variable analysis. J Parenteral Enteral Nutr. 2011;35(5):596–602.
  • Harvey K, Xu Z, Walker C, et al. Parenteral lipid emulsions in guinea pigs differentially influence plasma and tissue levels of fatty acids, squalene, cholesterol, and phytosterols. Lipids. 2014;49(8):777–793.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.