Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form

References

• Koziolek M, Grimm M, Schneider F, et al. Navigating the human gastrointestinal tract for oral drug delivery: uncharted waters and new frontiers. Adv Drug Deliv Rev. 2016 Jun;1(101):75–88.
   Google Scholar
• Mandal UK, Chatterjee B, Senjoti FG. Gastro-retentive drug delivery systems and their in vivo success: A recent update. Asian J Pharm Sci. 2016 Oct 1;11(5):575–584.
   Google Scholar
• Lopes CM, Bettencourt C, Rossi A, et al. Overview on gastroretentive drug delivery systems for improving drug bioavailability. Int J Pharm. 2016 Aug 20;510(1):144–158.
   PubMedGoogle Scholar
• Awasthi R, Kulkarni GT. Decades of research in drug targeting to the upper gastrointestinal tract using gastroretention technologies: where do we stand? Drug Deliv. 2016;23(2):378–394.
   PubMed Web of Science ®Google Scholar
• Nayak AK, Maji R, Das B. Gastroretentive drug delivery systems: a review. Asian J Pharm Clin Res. 2010(1):9.
   Google Scholar
• Pathak K, Akhtar N, Singh S. Gastroretentive carrier systems in the delivery of therapeutic actives: an updated patent review. Pharm Pat Anal. 2015;4(6):453–474.
   PubMed Web of Science ®Google Scholar
• Streubel A, Siepmann J, Bodmeier R. Gastroretentive drug delivery systems. Expert Opin Drug Deliv. 2006 Mar 28;3(2):217–233.
   PubMedGoogle Scholar
• Pawar VK, Kansal S, Garg G, et al. Gastroretentive dosage forms: A review with special emphasis on floating drug delivery systems. Drug Deliv. 2011 Feb 1;18(2):97–110.
   PubMed Web of Science ®Google Scholar
• Hwang S-J, Park H, Park K. Gastric retentive drug-delivery systems. Crit Rev Ther Drug Carr Syst. 1998;15(3):42.
   Web of Science ®Google Scholar
• Prinderre P, Sauzet C, Fuxen C. Advances in gastro retentive drug-delivery systems. Expert Opin Drug Deliv. 2011 Sep 1;8(9):1189–1203.
   PubMed Web of Science ®Google Scholar
• Davis SS, Hardy JG, Fara JW. Transit of pharmaceutical dosage forms through the small intestine. Gut. 1986 Aug 1;27(8):886–892.
   PubMed Web of Science ®Google Scholar
• Waterman KC. A critical review of gastric retentive controlled drug delivery. Pharm Dev Technol. 2007;12(1):1–10.
   PubMed Web of Science ®Google Scholar
• Sathish D, Himabindu S, Kumar YS. Shayeda null, Rao YM. Floating Drug Delivery Systems Prolonging Gastric Residence Time: Review Curr Drug Deliv. 2011 Sep;8(5):494–510.
   Google Scholar
• Pawar VK, Kansal S, Asthana S, et al. Industrial perspective of gastroretentive drug delivery systems: physicochemical, biopharmaceutical, technological and regulatory consideration. Expert Opin Drug Deliv. 2012 May;9(5):551–565.
   PubMed Web of Science ®Google Scholar
• Malik Z, Sankineni A, Parkman HP. Assessing pyloric sphincter pathophysiology using EndoFLIP in patients with gastroparesis. Neurogastroenterol Motil Off J Eur Gastrointest Motil Soc. 2015 Apr;27(4):524–531.
   PubMed Web of Science ®Google Scholar
• Ferrua M, Singh R. Modeling the fluid dynamics in a human stomach to gain insight of food digestion. J Food Sci. 2010 Sep;75(7):R151–62.
   PubMed Web of Science ®Google Scholar
• Depomed. Acuform® Drug Delivery [Internet]. Enhancing therapies for optimized drug delivery. [ cited 2018 May 1]. Available from: http://www.depomed.com/technology
   Google Scholar
• Technology | The Accordion PillTM [Internet]. IntecPharma. [cited 2018 May 1]. Available from: http://intecpharma.com/technology/
   Google Scholar
• IntecPharma. The Accordion PillTM Carbidopa/Levodopa: AP – CD/LD [Internet]. IntecPharma pipeline. [ cited 2018 May 21]. Available from: http://intecpharma.com/pipleline/ap-cdld/
   Google Scholar
• Navon N, Weiss Z, Gendreau RM, Meckler J. Optimizing Delivery of Carbidopa/Levodopa via the Accordion PillTM: Comparative PK and Safety From 2 Randomized Crossover Studies in Healthy Volunteers (P2.040). Neurology [Internet]. 2018 Apr 10;90 (15 Supplement).
   Google Scholar
• Cargill R, Caldwell LJ, Engle K, Fix JA, Porter PA, Gardner CR. Controlled Gastric Emptying. 1. Effects of physical properties on gastric residence times of nondisintegrating geometric shapes in beagle dogs. Pharm Res. 1988;05(8):533–536.
   Google Scholar
• Fix JA, Cargill R, Engle K. Controlled gastric emptying. III. Gastric Residence Time of a Nondisintegrating Geometric Shape in Human Volunteers. Pharm Res. 1993 Jul;10(7):1087–1089.
   Google Scholar
• Bellinger AM, Jafari M, Grant TM, et al. Oral, ultra-long-lasting drug delivery: application toward malaria elimination goals. Sci Transl Med. 2016 Nov 16;8(365):365ra157–365ra157.
   PubMed Web of Science ®Google Scholar
• Zhang S, Bellinger AM, Glettig DL, et al. A pH-responsive supramolecular polymer gel as an enteric elastomer for use in gastric devices. Nat Mater. 2015 Oct;14(10):1065–1071.
   PubMed Web of Science ®Google Scholar
• Kirtane AR, Abouzid O, Minahan D, et al. Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy. Nat Commun. 2018 Jan 9;9(1):2.
   PubMedGoogle Scholar
• Liu J, Pang Y, Zhang S, et al. Triggerable tough hydrogels for gastric resident dosage forms. Nat Commun. 2017 Jul 25;8(1):124.
   PubMedGoogle Scholar
• Dressman JB, Reppas C. In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs. Eur J Pharm Sci Off J Eur Fed Pharm Sci. 2000 Oct;11(Suppl 2):S73–80.
   PubMed Web of Science ®Google Scholar
• Cargill R, Engle K, Gardner CR, et al. Controlled gastric emptying. II. In vitro erosion and gastric residence times of an erodible device in beagle dogs. Pharm Res. 1989;Jun;6(6):506–509.
   PubMed Web of Science ®Google Scholar
• Roberts JA, Kruger P, Paterson DL, et al. Antibiotic resistance–what’s dosing got to do with it? Crit Care Med. 2008 Aug;36(8):2433–2440.
   PubMed Web of Science ®Google Scholar
• Guillemot D, Carbon C, Balkau B, et al. Low dosage and long treatment duration of β-lactam: risk factors for carriage of penicillin-resistant streptococcus pneumoniae. JAMA. 1998 Feb 4;279(5):365–370.
   PubMed Web of Science ®Google Scholar
• Osterberg L, Blaschke T. Adherence to Medication. N Engl J Med. 2005 Aug 4;353(5):487–497.
   PubMed Web of Science ®Google Scholar
• Coleman CI, Limone B, Sobieraj DM, et al. Dosing frequency and medication adherence in chronic disease. J Manag Care Pharm JMCP. 2012 Sep;18(7):527–539.
   PubMed Web of Science ®Google Scholar
• Iglay K, Cao X, Mavros P, et al. Review and meta-analysis of medication adherence with once-weekly versus once-daily therapy. Clin Ther. 2015 Aug;37(8):1813–1821.e1.
   PubMed Web of Science ®Google Scholar
• Cohen MS, Chen YQ, McCauley M, et al. Antiretroviral therapy for the prevention of HIV-1 transmission. N Engl J Med. 2016 Sep 1;375(9):830–839.
   PubMed Web of Science ®Google Scholar
• Dehne KL, Dallabetta G, Wilson D, et al. HIV prevention 2020: a framework for delivery and a call for action. Lancet HIV. 2016;3(7):e323–332.
   PubMed Web of Science ®Google Scholar
• Elion R, Coleman M. The preexposure prophylaxis revolution: from clinical trials to routine practice: implementation view from the USA. Curr Opin HIV AIDS. 2016 Jan;11(1):67–73.
   PubMed Web of Science ®Google Scholar
• Deeks SG, Lewin SR, Havlir DV. The end of AIDS: HIV infection as a chronic disease. Lancet Lond Engl. 2013 Nov 2;382(9903):1525–1533.
   PubMed Web of Science ®Google Scholar
• Ho DD, Pomerantz RJ, Kaplan JC. Pathogenesis of infection with human immunodeficiency virus. N Engl J Med. 1987 Jul 30;317(5):278–286.
   PubMed Web of Science ®Google Scholar
• Streeck H, D’Souza MP, Littman DR, et al. Harnessing CD4+ T cell responses in HIV vaccine development. Nat Med. 2013 Feb;19(2):143–149.
   PubMed Web of Science ®Google Scholar
• Cihlar T, Fordyce M. Current status and prospects of HIV treatment. Curr Opin Virol. 2016;18:50–56.
   PubMed Web of Science ®Google Scholar
• Choudhry NK, Avorn J, Glynn RJ, et al. Full coverage for preventive medications after myocardial infarction. N Engl J Med. 2011 Dec 1;365(22):2088–2097.
   PubMed Web of Science ®Google Scholar