15,068
Views
53
CrossRef citations to date
0
Altmetric
Editorial

The prodrug approach in the era of drug design

&
Pages 1-5 | Received 28 Sep 2018, Accepted 26 Nov 2018, Published online: 18 Dec 2018

References

  • Peppercorn MA. Sulfasalazine: pharmacology, clinical use, toxicity, and related new drug development. Ann Intern Med. 1984;101(3):377–386.
  • Rautio J, Meanwell NA, Di L, et al. The expanding role of prodrugs in contemporary drug design and development [Review Article]. Nat Rev Drug Discov. 2018 Aug;17(8):559–587. PubMed PMID: 29700501.
  • Najjar A, Rajabi N, Karaman R. Recent approaches to platinum(iv) prodrugs: a variety of strategies for enhanced delivery and efficacy. Curr Pharm Des. 2017;23(16):2366–2376. PubMed PMID: 28155621; eng.
  • Brams M, Mao AR, Doyle RL. Onset of efficacy of long-acting psychostimulants in pediatric attention-deficit/hyperactivity disorder. Postgrad Med. 2008 Sep;120(3):69–88. PubMed PMID: 18824827; eng.
  • Hughes B. 2008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93–96. PubMed PMID: 19180096; eng.
  • Hughes B. 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89–92. PubMed PMID: 20118952; eng.
  • Mullard A. 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82–85. PubMed PMID: 21283092; eng.
  • Mullard A. 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91–94. PubMed PMID: 22293555; eng.
  • Mullard A. 2012 FDA drug approvals. Nat Rev Drug Discov. 2013 Feb;12(2):87–90. PubMed PMID: 23370234; eng.
  • Mullard A. 2013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85–89. PubMed PMID: 24481294; eng.
  • Mullard A. 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77–81. PubMed PMID: 25633781; eng.
  • Mullard A. 2015 FDA drug approvals. Nat Rev Drug Discov. 2016 Feb;15(2):73–76. PubMed PMID: 26837582; eng.
  • Mullard A. 2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73–76. PubMed PMID: 28148938; eng.
  • Mullard A. 2017 FDA drug approvals. Nat Rev Drug Discov. 2018 Feb 1;17(2):150. PubMed PMID: 29386602; eng.
  • Sinokrot H, Smerat T, Najjar A, et al. Advanced prodrug strategies in nucleoside and non-nucleoside antiviral agents: a review of the recent five years. 2017 Oct 16;22(10). PubMed PMID: 29035325. DOI:10.3390/molecules22101736
  • Karaman R. Prodrugs design: a new era. New York, USA: Nova Science Publishers, Incorporated; 2014.
  • Haddad F, Sawalha M, Khawaja Y, et al. Dopamine and levodopa prodrugs for the treatment of parkinson’s disease. Molecules . 2018;23(1):40.
  • Karaman R. Prodrugs design based on inter- and intramolecular chemical processes. Chem Biol Drug Des. 2013;82(6):643–668.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.