Multi-functional chitosan-based smart hydrogels mediated biomedical application

References

• Zhang YS, Khademhosseini A. Advances in engineering hydrogels. Science. 2017;356(6337):500–510.
   Web of Science ®Google Scholar
• Gooneh-Farahani S, Naimi-Jamal MR, Naghib SM. Stimuli-responsive graphene-incorporated multifunctional chitosan for drug delivery applications: a review. Expert Opin Drug Deliv. 2018;16(1):79–99.
   PubMed Web of Science ®Google Scholar
• Griffin DR, Weaver WM, Scumpia PO, et al. Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks. Nat Mater. 2015;14(7):737–744.
   PubMed Web of Science ®Google Scholar
• Chen Q, Wang C, Zhang X, et al. In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment. Nat Nanotechnol. 2019;14(1):89–97.
   PubMed Web of Science ®Google Scholar
• Koffler J, Zhu W, Qu X, et al. Biomimetic 3D-printed scaffolds for spinal cord injury repair. Nat Med. 2019. DOI:10.1038/s41591-018-0296-z
   PubMed Web of Science ®Google Scholar
• Fernandez-Castano Romera M, Gostl R, Shaikh H, et al. Mimicking active biopolymer networks with a synthetic hydrogel. J Am Chem Soc. 2019. DOI:10.1021/jacs.8b10659
   PubMed Web of Science ®Google Scholar
• Cruz-Acuna R, Quiros M, Farkas AE, et al. Synthetic hydrogels for human intestinal organoid generation and colonic wound repair. Nat Cell Biol. 2017;19(11):1326–1335.
   PubMed Web of Science ®Google Scholar
• Zou JL, Liu S, Sun JH, et al. Peripheral nerve-derived matrix hydrogel promotes remyelination and inhibits Synapse Formation. Adv Funct Mater. 2018;28:1705739.
   Web of Science ®Google Scholar
• Lin T, Liu S, Chen SH, et al. Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects. Acta Biomater. 2018;73:326–338.
   PubMed Web of Science ®Google Scholar
• Zhao L, Niu L, Liang H, et al. pH and glucose dual-responsive injectable hydrogels with insulin and fibroblasts as bioactive dressings for diabetic wound healing. ACS Appl Mater Interfaces. 2017;9(43):37563–37574.
   PubMed Web of Science ®Google Scholar
• Hsieh FY, Tao L, Wei Y, et al. A novel biodegradable self-healing hydrogel to induce blood capillary formation. Npg Asia Mater. 2017;9.
   Web of Science ®Google Scholar
• Kisiday J, Jin M, Kurz B, et al. Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci U S A. 2002;99(15):9996–10001.
   PubMed Web of Science ®Google Scholar
• Liang XC, Wang XL, Xu Q, et al. Rubbery Chitosan/Carrageenan hydrogels constructed through an electroneutrality system and their potential application as Cartilage Scaffolds. Biomacromolecules. 2018;19(2):340–352.
   PubMed Web of Science ®Google Scholar
• Wei JY, Xue W, Yu XF, et al. pH Sensitive phosphorylated chitosan hydrogel as vaccine delivery system for intramuscular immunization. J Biomater Appl. 2017;31(10):1358–1369.
   PubMed Web of Science ®Google Scholar
• Bhavsar C, Momin M, Gharat S, et al. Functionalized and graft copolymers of chitosan and its pharmaceutical applications. Expert Opin Drug Deliv. 2017;14(10):1189–1204.
   PubMed Web of Science ®Google Scholar
• Qu J, Zhao X, Ma PX, et al. pH-responsive self-healing injectable hydrogel based on N-carboxyethyl chitosan for hepatocellular carcinoma therapy. Acta Biomater. 2017;58:168–180.
   PubMed Web of Science ®Google Scholar
• Bb D, Hc G, Jh S, et al. Tough and cell-compatible chitosan physical hydrogels for mouse bone mesenchymal stem cells in vitro. ACS Appl Mater Interfaces. 2016;8(30):19739–19746.
   PubMed Web of Science ®Google Scholar
• Shariatinia Z. Pharmaceutical applications of chitosan. Adv Colloid Interface Sci. 2019;263:131–194.
   PubMed Web of Science ®Google Scholar
• Xiong W, Zhou HT, Zhang C, et al. An amino acid-based gelator for injectable and multi-responsive hydrogel. Chin Chem Lett. 2017;28(11):2125–2128.
   Web of Science ®Google Scholar
• Wang L, Li BQ, Xu F, et al. UV-crosslinkable and thermo-responsive chitosan hybrid hydrogel for NIR-triggered localized on-demand drug delivery. Carbohydr Polym. 2017;174:904–914.
   PubMed Web of Science ®Google Scholar
• Yang DH, Seo DI, Lee DW, et al. Preparation and evaluation of visible-light cured glycol chitosan hydrogel dressing containing dual growth factors for accelerated wound healing. J Ind Eng Chem. 2017;53:360–370.
   Web of Science ®Google Scholar
• Wu YB, Guo BL, Ma PX. Injectable electroactive hydrogels formed via host guest interactions. ACS Macro Lett. 2014;3(11):1145–1150.
   PubMed Web of Science ®Google Scholar
• Cheng RY, Yan YF, Liu H, et al. Mechanically enhanced lipo-hydrogel with controlled release of multi-type drugs for bone regeneration. ACS Appl Mater Interfaces. 2018;12:294–308.
   Google Scholar
• Kim S, Cui ZK, Fan JB, et al. Photocrosslinkable chitosan hydrogels functionalized with the RGD peptide and phosphoserine to enhance osteogenesis. J Mat Chem B. 2016;4(31):5289–5298.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Shi C, Yang XD, et al. pH- and temperature-sensitive hydrogel nanoparticles with dual photoluminescence for bioprobes. ACS Nano. 2016;10(6):5856–5863.
   PubMed Web of Science ®Google Scholar
• Hu LF, Zhang PP, Wang X, et al. pH-sensitive carboxymethyl chitosan hydrogels via acid-labile ortho ester linkage for potential biomedical applications. Carbohydr Polym. 2017;178:166–179.
   PubMed Web of Science ®Google Scholar
• Lu M, Liu Y, Huang YC, et al. Fabrication of photo-crosslinkable glycol chitosan hydrogel as a tissue adhesive. Carbohydr Polym. 2018;181:668–674.
   PubMed Web of Science ®Google Scholar
• Demirtaş TT, Irmak G, Gumusderelioglu M. A bioprintable form of chitosan hydrogel for bone tissue engineering. Biofabrication. 2017;9:035003.
   PubMed Web of Science ®Google Scholar
• Seong JS, Yun ME, Park SN. Surfactant-stable and pH-sensitive liposomes coated with N-succinyl-chitosan and chitooligosaccharide for delivery of quercetin. Carbohydr Polym. 2018;181:659–667.
   PubMed Web of Science ®Google Scholar
• Xie CX, Tian TC, Yu ST, et al. pH-sensitive hydrogel based on carboxymethyl chitosan/sodium alginate and its application for drug delivery. J Appl Polym Sci. 2019;136(1):46911.
   Web of Science ®Google Scholar
• Naseeruteen F, Hamid NSA, Suah FBM, et al. Adsorption of malachite green from aqueous solution by using novel chitosan ionic liquid beads. Int J Biol Macromol. 2018;107:1270–1277.
   PubMed Web of Science ®Google Scholar
• Naderi Z, Azizian J. Synthesis and characterization of carboxymethyl chitosan/Fe3O4 and MnFe2O4 nanocomposites hydrogels for loading and release of curcumin. J Photochem Photobiol, B. 2018;185:206–214.
   PubMed Web of Science ®Google Scholar
• Treenate P, Monvisade P. In vitro drug release profiles of pH-sensitive hydroxyethylacryl chitosan/sodium alginate hydrogels using paracetamol as a soluble model drug. Int J Biol Macromol. 2017;99:71–78.
   PubMed Web of Science ®Google Scholar
• Zhao X, Zou X, Ye L. Controlled pH- and glucose-responsive drug release behavior of cationic chitosan based nano-composite hydrogels by using graphene oxide as drug nanocarrier. J Ind Eng Chem. 2017;49:36–45.
   Web of Science ®Google Scholar
• Zhou XH, Wang LC, Xu YJ, et al. A pH and magnetic dual-response hydrogel for synergistic chemo-magnetic hyperthermia tumor therapy. RSC Adv. 2018;8(18):9812–9821.
   PubMed Web of Science ®Google Scholar
• Xu H, Matysiak S. Effect of pH on chitosan hydrogel polymer network structure. Chem Comm. 2017;53(53):7373–7376.
   PubMed Web of Science ®Google Scholar
• Wang YM, Wang J, Yuan ZY, et al. Chitosan cross-linked poly(acrylic acid) hydrogels: drug release control and mechanism. Colloids Surf B Biointerfaces. 2017;152:252–259.
   PubMed Web of Science ®Google Scholar
• Bhattarai N, Gunn J, Zhang M. Chitosan-based hydrogels for controlled, localized drug delivery. Adv Drug Delivery Rev. 2010;62(1):83–99.
   PubMed Web of Science ®Google Scholar
• Li X, Wu M, Gu L, et al. A single dose of thermal-sensitive biodegradable hybrid hydrogel promotes functional recovery after spinal cord injury. Appl Mater Today. 2019;14:66–75.
   Web of Science ®Google Scholar
• Fan R, Tong A, Li X, et al. Enhanced antitumor effects by docetaxel/LL37-loaded thermosensitive hydrogel nanoparticles in peritoneal carcinomatosis of colorectal cancer. Int J Nanomedicine. 2015;10:7291–7305.
   PubMed Web of Science ®Google Scholar
• Chenite A, Chaput C, Wang D, et al. Novel injectable neutral solutions of chitosan form biodegradable gels in situ. Biomaterials. 2000;21(21):2155–2161.
   PubMed Web of Science ®Google Scholar
• Shi J, Zheng DX, Liu YX, et al. Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice. Cancer Res. 2005;65(5):1687–1692.
   PubMed Web of Science ®Google Scholar
• Yun Q, Wang SS, Xu S, et al. Use of 5-fluorouracil loaded micelles and cisplatin in thermosensitive chitosan hydrogel as an efficient therapy against Colorectal Peritoneal Carcinomatosis. Macromol Biosci. 2017;17(4):1600262.
   Web of Science ®Google Scholar
• Chou PY, Chen SH, Chen CH, et al. Thermo-responsive in-situ forming hydrogels as barriers to prevent post-operative peritendinous adhesion. Acta Biomater. 2017;63:85–95.
   PubMed Web of Science ®Google Scholar
• Ohya S, Sonoda H, Nakayama Y, et al. The potential of poly(N-isopropylacrylamide) (PNIPAM)-grafted hyaluronan and PNIPAM-grafted gelatin in the control of post-surgical tissue adhesions. Biomaterials. 2005;26(6):655–659.
   PubMed Web of Science ®Google Scholar
• Yuan M, Bi B, Huang JC, et al. Thermosensitive and photocrosslinkable hydroxypropyl chitin-based hydrogels for biomedical applications. Carbohydr Polym. 2018;192:10–18.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Liang K, Zhao S, et al. Photopolymerized maleilated chitosan/methacrylated silk fibroin micro/nanocomposite hydrogels as potential scaffolds for cartilage tissue engineering. Int J Biol Macromol. 2018;108:383–390.
   PubMed Web of Science ®Google Scholar
• Shao J, Ruan C, Xie H, et al. Black-phosphorus-incorporated hydrogel as a sprayable and biodegradable photothermal platform for postsurgical treatment of cancer. Adv Sci. 2018;5:1700848.
   Web of Science ®Google Scholar
• Shao J, Xie H, Wang H, et al. 2D material-based nanofibrous membrane for photothermal cancer therapy. ACS Appl Mater Interfaces. 2018;10(1):1155–1163.
   PubMed Web of Science ®Google Scholar
• Carvalho IC, Mansur HS. Engineered 3D-scaffolds of photocrosslinked chitosan-gelatin hydrogel hybrids for chronic wound dressings and regeneration. Mater Sci Eng C. 2017;78:690–705.
   PubMed Web of Science ®Google Scholar
• He M, Han BQ, Jiang ZW, et al. Synthesis of a chitosan-based photo-sensitive hydrogel and its biocompatibility and biodegradability. Carbohydr Polym. 2017;166:228–235.
   PubMed Web of Science ®Google Scholar
• Zhong C, Wu J, Ca R-K, et al. Synthesis, characterization and cytotoxicity of photo-crosslinked maleic chitosan-polyethylene glycol diacrylate hybrid hydrogels. Acta Biomater. 2010;6(10):3908–3918.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Liu JG, Chen WM, et al. Efficacy of thermosensitive chitosan/beta-glycerophosphate hydrogel loaded with beta-cyclodextrin-curcumin for the treatment of cutaneous wound infection in rats. Exp Ther Med. 2018;15(2):1304–1313.
   PubMed Web of Science ®Google Scholar
• Yoon SJ, Hyun H, Lee DW, et al. Visible light-cured glycol chitosan hydrogel containing a Beta-Cyclodextrin-Curcumin inclusion complex improves wound healing in vivo. Molecules. 2017;22(9):1513.
   PubMed Web of Science ®Google Scholar
• Liu H, Wang CY, Li C, et al. A functional chitosan-based hydrogel as a wound dressing and drug delivery system in the treatment of wound healing. RSC Adv. 2018;8(14):7533–7549.
   PubMed Web of Science ®Google Scholar
• Zhang M, Wang J, Jin Z. Supramolecular hydrogel formation between chitosan and hydroxypropyl beta-cyclodextrin via Diels-Alder reaction and its drug delivery. Int J Biol Macromol. 2018;114:381–391.
   PubMed Web of Science ®Google Scholar
• Wei W, Zhang Q, Zhou W, et al. Immunomodulatory application of engineered hydrogels in regenerative medicine. Appl Mater Today. 2019;14:126–136.
   Web of Science ®Google Scholar
• Tessmar JK, Gopferich AM. Matrices and scaffolds for protein delivery in tissue engineering. Adv Drug Delivery Rev. 2007;59(4–5):274–291.
   PubMed Web of Science ®Google Scholar
• Lee KY, Mooney DJ. Hydrogels for tissue engineering. Chem Rev. 2001;101(7):1869–1879.
   PubMed Web of Science ®Google Scholar
• Li X, Ye X, Qi J, et al. EGF and curcumin co-encapsulated nanoparticle/hydrogel system as potent skin regeneration agent. Int J Nanomed. 2016;11:3993–4009.
   PubMed Web of Science ®Google Scholar
• Tran NQ, Joung YK, Lih E, et al. In situ forming and rutin-releasing chitosan hydrogels as injectable dressings for dermal wound healing. Biomacromolecules. 2011;12(8):2872–2880.
   PubMed Web of Science ®Google Scholar
• Ferreira MOG, Leite LLR, de Lima IS, et al. Chitosan Hydrogel in combination with Nerolidol for healing wounds. Carbohydr Polym. 2016;152:409–418.
   PubMed Web of Science ®Google Scholar
• Guo Q, Liu C, Hai B, et al. Chitosan conduits filled with simvastatin/Pluronic F-127 hydrogel promote peripheral nerve regeneration in rats. J Biomed Mater Res, Part B. 2018;106(2):787–799.
   PubMed Web of Science ®Google Scholar
• Elviri L, Bianchera A, Bergonzi C, et al. Controlled local drug delivery strategies from chitosan hydrogels for wound healing. Expert Opin Drug Deliv. 2017;14(7):897–908.
   PubMed Web of Science ®Google Scholar
• Hoque J, Prakash RG, Paramanandham K, et al. Biocompatible injectable hydrogel with potent wound healing and antibacterial properties. Mol Pharm. 2017;14(4):1218–1230.
   PubMed Web of Science ®Google Scholar
• Zhang W, Jin X, Li H, et al. Injectable and body temperature sensitive hydrogels based on chitosan and hyaluronic acid for pH sensitive drug release. Carbohydr Polym. 2018;186:82–90.
   PubMed Web of Science ®Google Scholar
• Xu JK, Strandman S, Zhu JXX, et al. Genipin-crosslinked catechol-chitosan mucoadhesive hydrogels for buccal drug delivery. Biomaterials. 2015;37:395–404.
   PubMed Web of Science ®Google Scholar
• Yu SH, Li Q, Li YN, et al. A novel hydrogel with dual temperature and pH responsiveness based on a nanostructured lipid carrier as an ophthalmic delivery system: enhanced trans-corneal permeability and bioavailability of nepafenac. New J Chem. 2017;41(10):3920–3929.
   Web of Science ®Google Scholar
• Qiao XS, Peng XT, Qiao J, et al. Evaluation of a photocrosslinkable hydroxyethyl chitosan hydrogel as a potential drug release system for glaucoma surgery. J Mater Sci-Mater Med. 2017;28(10):149.
   PubMed Web of Science ®Google Scholar
• Moreno M, Pow PY, Tabitha TST, et al. Modulating release of ranibizumab and aflibercept from thiolated chitosan-based hydrogels for potential treatment of ocular neovascularization. Expert Opin Drug Deliv. 2017;14(8):913–925.
   PubMed Web of Science ®Google Scholar
• Huang JF, Zhong J, Chen GP, et al. A hydrogel-based hybrid theranostic contact lens for Fungal Keratitis. ACS Nano. 2016;10(7):6464–6473.
   PubMed Web of Science ®Google Scholar
• Yan Y, Li MN, Yang D, et al. Construction of injectable double-network hydrogels for cell delivery. Biomacromolecules. 2017;18(7):2128–2138.
   PubMed Web of Science ®Google Scholar
• Pereira DR, Canadas RF, Silva-Correia J, et al. Injectable gellan-gum/hydroxyapatite-based bilayered hydrogel composites for osteochondral tissue regeneration. Appl Mater Today. 2018;12:309–321.
   Web of Science ®Google Scholar
• Kim S, Kawai T, Wang D, et al. Engineering a dual-layer chitosan-lactide hydrogel to create endothelial cell aggregate-induced microvascular networks in vitro and increase blood perfusion in vivo. ACS Appl Mater Interfaces. 2016;8(30):19245–19255.
   PubMed Web of Science ®Google Scholar
• Elizalde-Pena EA, Quintero-Ortega IA, Zarate-Trivino DG, et al. (Chitosan-g-glycidyl methacrylate)-xanthan hydrogel implant in Wistar rats for spinal cord regeneration. Mater Sci Eng C-Mater Biol Appl. 2017;78:892–900.
   PubMed Web of Science ®Google Scholar
• Sun GH, Feng C, Jiang CQ, et al. Thermo-responsive hydroxybutyl chitosan hydrogel as artery intervention embolic agent for hemorrhage control. Int J Biol Macromol. 2017;105:566–574.
   PubMed Web of Science ®Google Scholar
• Yuan DD, Jacquier JC, O’Riordan ED. Entrapment of proteins and peptides in chitosan-polyphosphoric acid hydrogel beads: A new approach to achieve both high entrapment efficiency and controlled in vitro release. Food Chem. 2018;239:1200–1209.
   PubMed Web of Science ®Google Scholar
• Tahrir FG, Ganji F, Mani AR, et al. In vitro and in vivo evaluation of thermosensitive chitosan hydrogel for sustained release of insulin. Drug Deliv. 2016;23(3):1038–1046.
   PubMed Web of Science ®Google Scholar
• Xu B, Jiang GH, Yu WJ, et al. Preparation of poly(lactic-co-glycolic acid) and chitosan composite nanocarriers via electrostatic self assembly for oral delivery of insulin. Mater Sci Eng C-Mater Biol Appl. 2017;78:420–428.
   PubMed Web of Science ®Google Scholar
• Highton AJ, Kojarunchitt T, Girardin A, et al. Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma. Immunol Cell Biol. 2015;93(7):634–640.
   PubMed Web of Science ®Google Scholar
• Umair S, Pernthaner A, Deng Q, et al. Preliminary evaluation of a thermosensitive chitosan hydrogel for Echinococcus granulosus vaccine delivery. Vet Parasitol. 2017;236:117–120.
   PubMed Web of Science ®Google Scholar
• Zhang C, Wang ZG, Li Y, et al. The preparation and physiochemical characterization of rapeseed protein hydrolysate-chitosan composite films. Food Chem. 2019;272:694–701.
   PubMed Web of Science ®Google Scholar
• Shu Y, Hao T, Yao FL, et al. RoY peptide-modified chitosan-based hydrogel to improve angiogenesis and cardiac repair under Hypoxia. ACS Appl Mater Interfaces. 2015;7(12):6505–6517.
   PubMed Web of Science ®Google Scholar
• Zhou YL, Zhao J, Sun XL, et al. Rapid gelling chitosan/polylysine hydrogel with enhanced bulk cohesive and interfacial adhesive force: mimicking features of epineurial matrix for peripheral Nerve Anastomosis. Biomacromolecules. 2016;17(2):622–630.
   PubMed Web of Science ®Google Scholar
• Wu DN, Zhang YN, Xu XT, et al. RGD/TAT-functionalized chitosan-graft-PEI-PEG gene nanovector for sustained delivery of NT-3 for potential application in neural regeneration. Acta Biomater. 2018;72:266–277.
   PubMed Web of Science ®Google Scholar
• Giacca MG. Virus-mediated gene transfer to induce therapeutic angiogenesis: where do we stand? Int J Nanomed. 2007;2(4):527–540.
   PubMed Web of Science ®Google Scholar
• Cao C, Yan CH, Hu ZQ, et al. Potential application of injectable chitosan hydrogel treated with siRNA in chronic rhinosinusitis therapy. Mol Med Rep. 2015;12(5):6688–6694.
   PubMed Web of Science ®Google Scholar
• Senapati S, Mahanta AK, Kumar S, et al. Controlled drug delivery vehicles for cancer treatment and their performance. Signal Transduct Target Ther. 2018;3:7. UNSP.
   PubMed Web of Science ®Google Scholar
• Ma ZW, Yang CX, Song W, et al. Chitosan Hydrogel as siRNA vector for prolonged gene silencing. J Nanobiotechnology. 2014;12:23.
   PubMed Web of Science ®Google Scholar
• Alinejad Y, Adoungotchodo A, Hui E, et al. An injectable chitosan/chondroitin sulfate hydrogel with tunable mechanical properties for cell therapy/tissue engineering. Int J Biol Macromol. 2018;113:132–141.
   PubMed Web of Science ®Google Scholar
• Flegeau K, Pace R, Gautier H, et al. Toward the development of biomimetic injectable and macroporous biohydrogels for regenerative medicine. Adv Colloid Interface Sci. 2017;247:589–609.
   PubMed Web of Science ®Google Scholar
• Mauri E, Sacchetti A, Vicario N, et al. Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems. Biomater Sci. 2018;6(3):501–510.
   PubMed Web of Science ®Google Scholar
• Hsieh W-C, Liau -J-J, Li Y-J. Characterization and Cell Culture of a Grafted Chitosan Scaffold for Tissue Engineering. Int J Polym Sci. 2015;2015:1–7.
   Google Scholar
• Feng X, Lu X, Huang D, et al. 3D porous chitosan scaffolds suit survival and neural differentiation of dental pulp stem cells. Cell Mol Neurobiol. 2014;34(6):859–870.
   PubMed Web of Science ®Google Scholar
• Liu H, Liu J, Qi C, et al. Thermosensitive injectable in-situ forming carboxymethyl chitin hydrogel for three-dimensional cell culture. Acta Biomater. 2016;35:228–237.
   PubMed Web of Science ®Google Scholar
• Mellati A, Kiamahalleh MV, Madani SH, et al. Poly(N-isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering. J Biomed Mater Res Part A. 2016;104(11):2764–2774.
   PubMed Web of Science ®Google Scholar
• Li Y, Zhang Y, Wei Y, et al. Preparation of chitosan-based injectable hydrogels and its application in 3D cell culture. J Visualized Exp. 2017;127:e56253.
   Google Scholar
• Cho MO, Li Z, Shim HE, et al. Bioinspired tuning of glycol chitosan for 3D cell culture. Npg Asia Mater. 2016;8:e309.
   Web of Science ®Google Scholar
• Wei YN, Wang QQ, Gao TT, et al. 3-D culture of human umbilical vein endothelial cells with reversible thermosensitive hydroxybutyl chitosan hydrogel. J Mater Sci. 2013;24(7):1781–1787.
   Web of Science ®Google Scholar
• Pati F, Gantelius J, Svahn HA. 3D bioprinting of tissue/organ models. Angew Chem-Int Ed. 2016;55(15):4650–4665.
   PubMed Web of Science ®Google Scholar
• Wang XH, Ao Q, Tian XH, et al. 3D bioprinting technologies for hard tissue and organ engineering. Materials. 2016;9(10):802.
   PubMed Web of Science ®Google Scholar
• Elviri L, Foresti R, Bergonzi C, et al. Highly defined 3D printed chitosan scaffolds featuring improved cell growth. Biomed Mater. 2017;12(4):045009.
   PubMed Web of Science ®Google Scholar
• Bozuyuk U, Yasa O, Yasa IC, et al. Light-triggered drug release from 3D-Printed Magnetic Chitosan Microswimmers. ACS Nano. 2018;12(9):9617–9625.
   PubMed Web of Science ®Google Scholar
• Intini C, Elviri L, Cabral J, et al. 3D-printed chitosan-based scaffolds: an in vitro study of human skin cell growth and an in-vivo wound healing evaluation in experimental diabetes in rats. Carbohydr Polym. 2018;199:593–602.
   PubMed Web of Science ®Google Scholar
• Ng WL, Yeong WY, Naing MW. Polyelectrolyte gelatin-chitosan hydrogel optimized for 3D bioprinting in skin tissue engineering. Int J Bioprinting. 2016;2(1):53–62.
   Web of Science ®Google Scholar
• Wu Q, Maire M, Lerouge S, et al. 3D printing of microstructured and stretchable Chitosan Hydrogel for guided cell growth. Adv Biosyst. 2017;1(6):1700058.
   Web of Science ®Google Scholar