254
Views
22
CrossRef citations to date
0
Altmetric
Original Research

Phytosterol-loaded CD44 receptor-targeted PEGylated nano-hybrid phyto-liposomes for synergistic chemotherapy

, , , , , , , ORCID Icon, & ORCID Icon show all
Pages 423-434 | Received 13 May 2019, Accepted 05 Feb 2020, Published online: 13 Feb 2020

References

  • Tran P, Lee S-E, Kim D-H, et al. Recent advances of nanotechnology for the delivery of anticancer drugs for breast cancer treatment. J Pharm Invest. 2019. DOI:10.1007/s40005-019-00459-7.
  • Gautam M, Thapa RK, Poudel BK, et al. Aerosol technique-based carbon-encapsulated hollow mesoporous silica nanoparticles for synergistic chemo-photothermal therapy. Acta Biomater. 2019;88:448–461.
  • Nguyen VD, Zheng S, Han J, et al. Nanohybrid magnetic liposome functionalized with hyaluronic acid for enhanced cellular uptake and near-infrared-triggered drug release. Colloids Surf B Biointerfaces. 2017;154:104–114.
  • Blasi P. Poly(lactic acid)/poly(lactic‑co‑glycolic acid)‑based microparticles: an overview. J Pharm Invest. 2019;49:337–346.
  • Lee S, Ryu JH, Park K, et al. Polymeric nanoparticle-based activatable near-infrared nanosensor for protease determination in vivo. Nano Lett. 2009;9:4412–4416.
  • Alibolandi M, Mohammadi M, Taghdisi SM, et al. Fabrication of aptamer decorated dextran coated nano-graphene oxide for targeted drug delivery. Carbohydr Polym. 2017;155:218–229.
  • Zalipsky S. Polyethylene glycol-lipid conjugates, stealth liposomes. Boca Raton, Florida: CRC Press; 2018. p. 113–122.
  • Gautam M, Ku SK, Kim JO, et al. A scalable on-demand platform to assemble base nanocarriers for combination cancer therapy. Nanoscale. 2018;10:11737–11744.
  • Milani D, Athiyah U, Hariyadi DM, et al. Surface modifications of liposomes for drug targeting. In: Pathak YV, editor. Surface modification of nanoparticles for targeted drug delivery. Cham: Springer International Publishing; 2019. p. 207–220.
  • Poudel BK, Gupta B, Ramasamy T, et al. PEGylated thermosensitive lipid-coated hollow gold nanoshells for effective combinational chemo-photothermal therapy of pancreatic cancer. Colloids Surf B Biointerfaces. 2017;160:73–83.
  • Torchilin V, Papisov M, Bogdanov A, et al. Molecular mechanism of liposome and immunoliposome steric protection with poly (ethylene glycol): theoretical and experimental proofs of the role of polymer chain flexibility, stealth liposomes. Boca Raton, Florida: CRC Press; 2018. p. 71–82.
  • Qhattal HSS, Hye T, Alali A, et al. Hyaluronan polymer length, grafting density, and surface poly(ethylene glycol) coating influence in vivo circulation and tumor targeting of hyaluronan-grafted liposomes. ACS Nano. 2014;8:5423–5440.
  • Chen W-H, Luo G-F, Zhang X-Z. recent advances in subcellular targeted cancer therapy based on functional materials. Adv Mater. 2019;31:1802725.
  • Hermann T, Patel DJ. Adaptive recognition by nucleic acid aptamers. Science. 2000;287:820–825.
  • Vandghanooni S, Eskandani M, Barar J, et al. Recent advances in aptamer-armed multimodal theranostic nanosystems for imaging and targeted therapy of cancer. Eur J Pharm Sci. 2018;117:301–312.
  • Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov. 2005;4:145–160.
  • Bartheldyová E, Effenberg R, Mašek J, et al. Hyaluronic acid surface modified liposomes prepared via orthogonal aminoxy coupling: synthesis of nontoxic aminoxylipids based on symmetrically α-branched fatty acids, preparation of liposomes by microfluidic mixing, and targeting to cancer cells expressing CD44. Bioconjug Chem. 2018;29:2343–2356.
  • Chen D, Dong X, Qi M, et al. Dual pH/redox responsive and CD44 receptor targeting hybrid nano-chrysalis based on new oligosaccharides of hyaluronan conjugates. Carbohydr Polym. 2017;157:1272–1280.
  • Cho H-J. Recent progresses in the development of hyaluronic acid-based nanosystems for tumor-targeted drug delivery and cancer imaging. J Pharm Invest. 2019. DOI:10.1007/s40005-019-00448-w.
  • Foley DA, O’Callaghan Y, O’Brien NM, et al. Synthesis and characterization of stigmasterol oxidation products. J Agric Food Chem. 2010;58:1165–1173.
  • Shahzad N, Khan W, Md S, et al. Phytosterols as a natural anticancer agent: current status and future perspective. Biomed Pharmacother. 2017;88:786–794.
  • Woyengo T, Ramprasath V, Jones P. Anticancer effects of phytosterols. Eur J Clin Nutr. 2009;63:813.
  • Lokhandwala A, Jain J. Plant-derived extracts and compounds: an alternative therapy against breast cancer, anticancer plants: natural products and biotechnological implements. Singapore: Springer; 2018. p. 465–480.
  • O’Callaghan YC, Foley DA, O’Connell NM, et al. Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line. J Agric Food Chem. 2010;58:10793–10798.
  • Velliangiri P, Subban R. Quantification of quercetin and stigmasterol of Couroupita guianensis aubl by HPTLC method and in-vitro cytototoxic activity by mtt assay of the methanol extract against hela, nih 3t3 and hepg2 cancer cell lines. Int J Pharm Pharmac Sci. 2012;4:126–130.
  • Shimizu K, Qi X-R, Maitani Y, et al. Targeting of soybean-derived sterylglucoside liposomes to liver tumors in rat and mouse models. Biol Pharm Bull. 1998;21:741–746.
  • Ramasamy T, Haidar ZS, Tran TH, et al. Layer-by-layer assembly of liposomal nanoparticles with PEGylated polyelectrolytes enhances systemic delivery of multiple anticancer drugs. Acta Biomater. 2014;10:5116–5127.
  • Sanson C, Schatz C, Le Meins J-F, et al. A simple method to achieve high doxorubicin loading in biodegradable polymersomes. J Control Release. 2010;147:428–435.
  • Gupta B, Pathak S, Poudel BK, et al. Folate receptor-targeted hybrid lipid-core nanocapsules for sequential delivery of doxorubicin and tanespimycin. Colloids Surf B Biointerfaces. 2017;155:83–92.
  • Thapa RK, Nguyen HT, Gautam M, et al. Hydrophobic binding peptide-conjugated hybrid lipid-mesoporous silica nanoparticles for effective chemo-photothermal therapy of pancreatic cancer. Drug Deliv. 2017;24:1690–1702.
  • Jiang HF, Wu Z, Bai X, et al. Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro. Oncol Lett. 2014;8:1139–1142.
  • Liang -C-C, Park AY, Guan J-L. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc. 2007;2:329–333.
  • Zylberberg C, Gaskill K, Pasley S, et al. Engineering liposomal nanoparticles for targeted gene therapy. Gene Ther. 2017;24:441.
  • Ruttala HB, Ramasamy T, Madeshwaran T, et al. Emerging potential of stimili-responsive nano-sized drug delivery systems for systemic applications. Arch Pharm Res. 2018;41:111–129.
  • Choi YH, Han H-K. Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics. J Pharm Invest. 2018;48:43–60.
  • Paolino D, Accolla ML, Cilurzo F, et al. Interaction between PEG lipid and DSPE/DSPC phospholipids: an insight of PEGylation degree and kinetics of de-PEGylation. Colloids Surf B Biointerfaces. 2017;155:266–275.
  • Trucillo P, Campardelli R, Reverchon E. Supercritical CO2 assisted liposomes formation: optimization of the lipidic layer for an efficient hydrophilic drug loading. J CO2 Util. 2017;18:181–188.
  • Aramaki K, Watanabe Y, Takahashi J, et al. Charge boosting effect of cholesterol on cationic liposomes. Colloids Surf A Physicochem Eng Asp. 2016;506:732–738.
  • Wang FC, Acevedo N, Marangoni AG. Encapsulation of phytosterols and phytosterol esters in liposomes made with soy phospholipids by high pressure homogenization. Food Funct. 2017;8:3964–3969.
  • Ravar F, Saadat E, Gholami M, et al. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. J Control Release. 2016;229:10–22.
  • Qhattal HSS, Hye T, Alali A, et al. Hyaluronan polymer length, grafting density, and surface poly (ethylene glycol) coating influence in vivo circulation and tumor targeting of hyaluronan-grafted liposomes. ACS Nano. 2014;8:5423.
  • Wu J, Fu H, Jiang Y, et al. Preparation and characterization of a novel polysialic acid–hyaluronan graft copolymer potential as dermal filler. Int J Biol Macromol. 2017;99:692–698.
  • Xu X, Ho W, Zhang X, et al. Cancer nanomedicine: from targeted delivery to combination therapy. Trends Mol Med. 2015;21:223–232.
  • Termsarasab U, Cho H-J, Kim DH, et al. Chitosan oligosaccharide–arachidic acid-based nanoparticles for anti-cancer drug delivery. Int J Pharm. 2013;441:373–380.
  • Fritze A, Hens F, Kimpfler A, et al. Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient. Biochim Biophys Acta - Biomembr. 2006;1758:1633–1640.
  • Sajadian S, Vatankhah M, Majdzadeh M, et al. Cell cycle arrest and apoptogenic properties of opium alkaloids noscapine and papaverine on breast cancer stem cells. Toxicol Mech Methods. 2015;25:388–395.
  • Chang G, Wang J, Zhang H, et al. CD44 targets Na+/H+ exchanger 1 to mediate MDA-MB-231 cells/’ metastasis via the regulation of ERK1/2. Br J Cancer. 2014;110:916–927.
  • Chen W, Zeng K, Liu H, et al. Cell membrane camouflaged hollow prussian blue nanoparticles for synergistic photothermal-/chemotherapy of cancer. Adv Funct Mater. 2017;27:1605795.
  • Lin WJ, Lee W-C, Shieh M-J. Hyaluronic acid conjugated micelles possessing CD44 targeting potential for gene delivery. Carbohydr Polym. 2017;155:101–108.
  • Azizi M, Ghourchian H, Yazdian F, et al. Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line. Sci Rep. 2017;7:5178.
  • Arakha M, Jha S. Effect of ZnONP surface defects on cytotoxic and antimicrobial propensities. In: Arakha M, Jha S, editors. Interfacial phenomena on biological membranes. Cham: Springer International Publishing; 2018. p. 91–110.
  • Guo C, Yin S, Yu H, et al. Photothermal ablation cancer therapy using homogeneous CsxWO3 nanorods with broad near-infra-red absorption. Nanoscale. 2013;5:6469–6478.
  • Le Q-V, Choi J, Oh Y-K. Nano delivery systems and cancer immunotherapy. J Pharm Invest. 2018;48:527–539.
  • Deb J, Majumder J, Bhattacharyya S, et al. A novel naproxen derivative capable of displaying anti-cancer and anti-migratory properties against human breast cancer cells. BMC Cancer. 2014;14:567.
  • Wang W, Xiong W, Zhu Y, et al. Protective effect of PEGylation against poly (amidoamine) dendrimer‐induced hemolysis of human red blood cells. J Biomed Mater Res Part B. 2010;93:59–64.
  • Dubey RD, Klippstein R, Wang JT-W, et al. Novel hyaluronic acid conjugates for dual nuclear imaging and therapy in CD44-expressing tumors in mice in vivo. Nanotheranostics. 2017;1:59.
  • Immordino ML, Dosio F, Cattel L. Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. Int J Nanomedicine. 2006;1:297–315.
  • Shah KN, Ditto AJ, Crowder DC, et al. Receptor-mediated attachment and uptake of hyaluronan conjugates by breast cancer cells. Mol Pharm. 2017;14:3968–3977.
  • Arpicco S, De Rosa G, Fattal E. Lipid-based nanovectors for targeting of CD44-overexpressing tumor cells. J Drug Deliv. 2013;2013:8.
  • Platt VM, Szoka FC. Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Mol Pharm. 2008;5:474–486.
  • Eliaz RE, Szoka FC. Liposome-encapsulated doxorubicin targeted to CD44. Cancer Res. 2001;61:2592.
  • Lee M-K. Clinical usefulness of liposomal formulations in cancer therapy: lessons from the experiences of doxorubicin. J Pharm Invest. 2019;49:203–214.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.