Pain relief outcomes using an SCS device capable of delivering combination therapy with advanced waveforms and field shapes

References

• Kriek N, Groeneweg JG, Stronks DL, et al. Preferred frequencies and waveforms for spinal cord stimulation in patients with complex regional pain syndrome: a multicentre, double-blind, randomized and placebo-controlled crossover trial. Eur J Pain. 2017 Mar;21(3):507–519.
   PubMed Web of Science ®Google Scholar
• Berg AP, Mekel-Bobrov N, Goldberg E, et al. Utilization of multiple spinal cord stimulation (SCS) waveforms in chronic pain patients. Expert Rev Med Devices. 2017 Aug;14(8):663–668.
   PubMed Web of Science ®Google Scholar
• Provenzano DA, Rebman J, Kuhel C, et al. The efficacy of high-density spinal cord stimulation among trial, implant, and conversion patients: a retrospective case series. Neuromodulation. 2017 Oct;20(7):654–660.
   PubMed Web of Science ®Google Scholar
• Kumar V, Prusik J, Lin Y, et al. Efficacy of alternating conventional stimulation and high frequency stimulation in improving spinal cord stimulation outcomes: a pilot study. Neuromodulation. 2018 July;21(5):466–471.
   PubMed Web of Science ®Google Scholar
• Duse G, Reverberi C, Dario A. Effects of multiple waveforms on patient preferences and clinical outcomes in patients treated with spinal cord stimulation for leg and/or back pain. Neuromodulation. 2019 Feb;22(2):200–207.
   PubMed Web of Science ®Google Scholar
• North J, Loudermilk E, Lee A, et al. Outcomes of a multicenter, prospective, crossover, randomized controlled trial evaluating subperception spinal cord Stimulation at ≤1.2 kHz in previously implanted subjects. Neuromodulation. 2019 July 2. [Epub ahead of print]. DOI:10.1111/ner.13015
   Web of Science ®Google Scholar
• Kapural L, Yu C, Doust MW, et al. Comparison of 10-kHz high-frequency and traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: 24-month results from a multicenter, randomized, controlled pivotal trial. Neurosurgery. 2016 Nov;79(5):667–677.
   PubMed Web of Science ®Google Scholar
• Kapural L, Yu C, Doust MW, et al. Novel 10-kHz high-frequency therapy (HF10 Therapy) is superior to traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: the SENZA-RCT randomized controlled trial. Anesthesiology. 2015;123:851–860.
   PubMed Web of Science ®Google Scholar
• Russo M, Verrills P, Mitchell B, et al. High frequency spinal cord stimulation at 10 kHz for the treatment of chronic pain: 6-month Australian clinical experience. Pain Physician. 2016;19:267–280.
   PubMed Web of Science ®Google Scholar
• De Andres J, Monsalve-Dolz V, Fabregat-Cid G, et al. Prospective, randomized blind effect-on-outcome study of conventional vs high-frequency spinal cord stimulation in patients with pain and disability due to failed back surgery syndrome. Pain Med. 2017 Dec 1;18(12):2401–2421.
   PubMed Web of Science ®Google Scholar
• DiBenedetto DJ, Wawrzyniak KM, Schatman ME, et al. 10 kHz spinal cord stimulation: a retrospective analysis of real-world data from a community-based, interdisciplinary pain facility. J Pain Res. 2018 Nov 20;11:2929–2941.
   PubMed Web of Science ®Google Scholar
• Muhammad S, Roeske S, Chaudhry SR, et al. Burst or high-frequency (10 kHz) spinal cord stimulation in failed back surgery syndrome patients with predominant back pain: one year comparative data. Neuromodulation. 2017 Oct;20(7):661–667.
   PubMed Web of Science ®Google Scholar
• Courtney P, Espinet A, Mitchell B, et al. Improved pain relief with burst spinal cord stimulation for two weeks in patients using tonic stimulation: results from a small clinical study. Neuromodulation. 2015 July;18(5):361–366.
   PubMed Web of Science ®Google Scholar
• de Vos CC, Bom MJ, Vanneste S, et al. Burst spinal cord stimulation evaluated in patients with failed back surgery syndrome and painful diabetic neuropathy. Neuromodulation. 2014 Feb;17(2):152–159.
   PubMed Web of Science ®Google Scholar
• Vesper J, Slotty P, Schu S, et al. Burst SCS Microdosing is as efficacious as standard burst SCS in treating chronic back and leg pain: results from a randomized controlled trial. Neuromodulation. 2019 Feb;22(2):190–193.
   PubMed Web of Science ®Google Scholar
• Thomson SJ, Tavakkolizadeh M, Love-Jones S, et al. Effects of rate on analgesia in kilohertz frequency spinal cord stimulation: results of the PROCO randomized controlled trial. Neuromodulation. 2018;21:67–76.
   PubMed Web of Science ®Google Scholar
• Veizi E, Hayek SM, North J, et al. Spinal cord stimulation (SCS) with anatomically guided (3D) neural targeting shows superior chronic axial low back pain relief compared to traditional SCS-LUMINA study. Pain Med. 2017;18:1534–1548.
   PubMed Web of Science ®Google Scholar
• Szucs P, Luz LL, Pinho R, et al. Axon diversity of lamina I local-circuit neurons in the lumbar spinal cord. J Comp Neurol. 2013;521(12):2719–2741.
   PubMed Web of Science ®Google Scholar
• Jensen MP, Brownstone RM. Mechanisms of spinal cord stimulation for the treatment of pain: still in the dark after 50 years. Eur J Pain. 2019;23(4):652–659.
   PubMed Web of Science ®Google Scholar
• Rubinstein JT. Axon termination conditions for electrical stimulation. IEEE Trans Biomed Eng. 1993;40(7):654–663.
   PubMed Web of Science ®Google Scholar
• McIntyre CC, Grill WM. Excitation of central nervous system neurons by nonuniform electric fields. Biophys J. 1999;76(2):878–888.
   PubMed Web of Science ®Google Scholar
• Gustafsson B, Jankowska E. Direct and indirect activation of nerve cells by electrical pulses applied extracellularly. J Physiol. 1976;258(1):33–61.
   PubMed Web of Science ®Google Scholar
• Radman T, Ramos RL, Brumberg JC, et al. Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro. Brain Stimul. 2009;2(4):215–228.e2283.
   PubMed Web of Science ®Google Scholar
• Dostrovsky JO, Levy R, Wu JP, et al. Microstimulation-induced inhibition of neuronal firing in human globus pallidus. J Neurophysiol. 2000;84(1):570–574.
   PubMed Web of Science ®Google Scholar
• Tiede J, Brown L, Gekht G, et al. Novel spinal cord stimulation parameters in patients with predominant back pain. Neuromodulation. 2013 July–Aug;16(4):370–375.
   PubMed Web of Science ®Google Scholar
• Al-Kaisy A, Van Buyten JP, Smet I, et al. Sustained effectiveness of 10 kHz high-frequency spinal cord stimulation for patients with chronic, low back pain: 24-month results of a prospective multicenter study. Pain Med. 2014 Mar;15(3):347–354.
   PubMed Web of Science ®Google Scholar
• Deer T, Slavin KV, Amirdelfan K, et al. Success using neuromodulation with BURST (SUNBURST) study: results from a prospective, randomized controlled trial using a novel burst waveform. Neuromodulation. 2018 Jan;21(1):56–66.
   PubMed Web of Science ®Google Scholar
• Haider N, Ligham D, Quave B, et al. Spinal cord stimulation (SCS) trial outcomes after conversion to a multiple waveform SCS system. Neuromodulation. 2018 July;21(5):504–507.
   PubMed Web of Science ®Google Scholar
• Melchior M, Poisbeau P, Gaumond I, et al. Insights into the mechanisms and the emergence of sex-differences in pain. Neuroscience. 2016 Dec;3(338):63–80.
   Google Scholar
• Zorina-Lichtenwalter K, Meloto CB, Khoury S, et al. Genetic predictors of human chronic pain conditions. Neuroscience. 2016 Dec;3(338):36–62.
   Google Scholar
• Pergolizzi J, Ahlbeck K, Aldington D, et al. The development of chronic pain: physiological CHANGE necessitates a multidisciplinary approach to treatment. Curr Med Res Opin. 2013;29(9):1127–1135.
   PubMed Web of Science ®Google Scholar
• Kumar K, Hunter G, Demeria D. Spinal cord stimulation in treatment of chronic benign pain: challenges in treatment planning and present status, a 22-year experience. Neurosurgery. 2006 Mar;58(3):481–496.
   PubMed Web of Science ®Google Scholar
• Holsheimer J, Khan YN, Raza SS, et al. Effects of electrode positioning on perception threshold and paresthesia coverage in spinal cord stimulation. Neuromodulation. 2007 Jan;10(1):34–41.
   PubMed Web of Science ®Google Scholar