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Original Article

Evaluation of polylactic acid nanoparticles safety using Drosophila model

, , , , &
Pages 1136-1143 | Received 16 Oct 2015, Accepted 10 Apr 2016, Published online: 16 May 2016

References

  • Adolfsson K, Schneider M, Hammarin G, Häcker U, Prinz CN. 2013. Ingestion of gallium phosphide nanowires has no adverse effect on Drosophila tissue function. Nanotechnology 24:285101
  • Ahmad Khanbeigi R, Kumar A, Sadouki F, Lorenz C, Forbes B, Dailey LA, Collins H. 2012. The delivered dose: Applying particokinetics to in vitro investigations of nanoparticle internalization by macrophages. J Control Release 162:259–66
  • Alaraby M, Annangi B, Hernández A, Creus A, Marcos R. 2015. A comprehensive study of the harmful effects of ZnO nanoparticles using Drosophila melanogaster as an in vivo model. J Hazard Mater 296:166–74
  • Apidianakis Y, Rahme LG. 2011. Drosophila melanogaster as a model for human intestinal infection and pathology. Dis Model Mech 4:21–30
  • Arts MJ, Schill RO, Knigge T, Eckwert H, Kammenga JE, Köhler HR. 2004. Stress proteins (hsp70, hsp60) induced in isopods and nematodes by field exposure to metals in a gradient near Avonmouth, UK. Ecotoxicology 13:739–55
  • Burhans WC, Heintz NH. 2009. The cell cycle is a redox cycle: linking phase-specific targets to cell fate. Free Radic Biol Med 47:1282–93
  • Crawford ED, Seaman JE, Barber AE, 2nd, David DC, Babbitt PC, Burlingame AL, Wells JA. 2012. Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. Cell Death Differ 19:2040–8
  • Danhier F, Ansorena E, Silva JM, Coco R, Le Breton A, Préat V. 2012. PLGA-based nanoparticles: an overview of biomedical applications. J Control Release 161:505–22
  • Di Gioia S, Trapani A, Castellani S, Carbone A, Belgiovine G, Craparo EF, et al. 2015. Nanocomplexes for gene therapy of respiratory diseases: Targeting and overcoming the mucus barrier. Pulm Pharmacol Ther 34:8–24
  • Essers MA, Weijzen S, de Vries-Smits AM, Saarloos I, de Ruiter ND, Bos JL, Burgering BM. 2004. FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J 23:4802–12
  • Fan Y, Moon JJ. 2015. Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy. Vaccines (Basel) 3:662–85
  • Fessi H, Puisieux F, Devissaguet JP, Ammoury N, Benita S. 1989. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int J Pharm 55:R1–4
  • Florentin A, Arama E. 2012. Caspase levels and execution efficiencies determine the apoptotic potential of the cell. J Cell Biol 196:513–27
  • Greer EL, Brunet A. 2005. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24:7410–25
  • Huang S, Chueh PJ, Lin YW, Shih TS, Chuang SM. 2009. Disturbed mitotic progression and genome segregation are involved in cell transformation mediated by nano-TiO2 long-term exposure. Toxicol Appl Pharmacol 241:182–94
  • Khanna P, Ong C, Bay BH, Baeg GH. 2015. Nanotoxicity: an interplay of oxidative stress, inflammation and cell death. Nanomaterials 5:1163–80
  • Kim JA, Åberg C, Salvati A, Dawson KA. 2011. Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population. Nat Nanotechnol 7:62–8
  • Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, et al. 2002. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419:316–21
  • Lamkanfi M, Declercq W, Kalai M, Saelens X, Vandenabeele P. 2002. Alice in caspase land. A phylogenetic analysis of caspases from worm to man. Cell Death Differ 9:358–61
  • Legaz S, Exposito JY, Borel A, Candusso MP, Megy S, Montserret R, et al. 2015. A purified truncated form of yeast Gal4 expressed in Escherichia coli and used to functionalize poly(lactic acid) nanoparticle surface is transcriptionally active in cellulo. Protein Expr Purif 113:94–101
  • Marano F, Hussain S, Rodrigues-Lima F, Baeza-Squiban A, Boland S. 2011. Nanoparticles: molecular targets and cell signalling. Arch Toxicol 85:733–41
  • Martorell Ò, Merlos-Suárez A, Campbell K, Barriga FM, Christov CP, Miguel-Aliaga I, et al. 2014. Conserved mechanisms of tumorigenesis in the Drosophila adult midgut. PLoS One 9:e88413
  • Mandal S, Guptan P, Owusu-Ansah E, Banerjee U. 2005. Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila. Dev Cell 9:843–54
  • Mandal S, Freije WA, Guptan P, Banerjee U. 2010. Metabolic control of G1-S transition: cyclin E degradation by p53-induced activation of the ubiquitin-proteasome system. J Cell Biol 188:473–9
  • Medema RH, Kops GJ, Bos JL, Burgering BM. 2000. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 404:782–7
  • Mollereau B, Ma D. 2014. The p53 control of apoptosis and proliferation: lessons from Drosophila. Apoptosis 19:1421–9
  • Morachis JM, Mahmoud EA, Almutairi A. 2012. Physical and chemical strategies for therapeutic delivery by using polymeric nanoparticles. Pharmacol Rev 64:505–19
  • Ong C, Yung LY, Cai Y, Bay BH, Baeg GH. 2015. Drosophila melanogaster as a model organism to study nanotoxicity. Nanotoxicology 9:396–403
  • Panariti A, Miserocchi G, Rivolta I. 2012. The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions? Nanotechnol Sci Appl 5:87–100
  • Pavot V, Berthet M, Rességuier J, Legaz S, Handké N, Gilbert SC, et al. 2014. Poly(lactic acid) and poly(lactic-co-glycolic acid) particles as versatile carrier platforms for vaccine delivery. Nanomedicine (Lond) 9:2703–18
  • Primard C, Rochereau N, Luciani E, Genin C, Delair T, Paul S, Verrier B. 2010. Traffic of poly(lactic acid) nanoparticulate vaccine vehicle from intestinal mucus to sub-epithelial immune competent cells. Biomaterials 31:6060–8
  • Rancourt RC, Hayes DD, Chess PR, Keng PC, O'Reilly MA. 2002. Growth arrest in G1 protects against oxygen-induced DNA damage and cell death. J Cell Physiol 193:26–36
  • Shukla AK, Pragya P, Chaouhan HS, Tiwari AK, Patel DK, Abdin MZ, Chowdhuri DK. 2014. Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease. PLoS One 9:e98886
  • Siddique YH, Haidari M, Khan W, Fatima A, Jyoti S, Khanam S, et al. 2015. Toxic potential of copper-doped ZnO nanoparticles in Drosophila melanogaster (Oregon R). Toxicol Mech Methods 25:425–32
  • Singh N, Jenkins GJ, Asadi R, Doak SH. 2010. Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION). Nano Rev 1. doi: 10.3402/nano.v1i0.5358
  • Singh RP, Ramarao P. 2013. Accumulated polymer degradation products as effector molecules in cytotoxicity of polymeric nanoparticles. Toxicol Sci 136:131–43
  • Tsujimoto Y. 1997. Apoptosis and necrosis: intracellular ATP level as a determinant for cell death modes. Cell Death Differ 4:429–34
  • Vecchio G, Galeone A, Brunetti V, Maiorano G, Sabella S, Cingolani R, Pompa PP. 2012. Concentration-dependent, size-independent toxicity of citrate capped AuNPs in Drosophila melanogaster. PLoS One 7:e29980
  • Vousden KH, Prives C. 2009. Blinded by the light: the growing complexity of p53. Cell 137:413–31
  • Zmasek CM, Godzik A. 2013. Evolution of the animal apoptosis network. Cold Spring Harb Perspect Biol 5:a008649

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