Quantitative biokinetics of titanium dioxide nanoparticles after intravenous injection in rats: Part 1

References

• Almeida JPM, Chen AL, Foster A, Drezek R. 2011. In vivo biodistribution of nanoparticles. Nanomedicine (Lond) 6:815–35.
   PubMed Web of Science ®Google Scholar
• ARA. 2009. Multiple-Path Particle Dosimetry Model (MPPD version 3.0). Albuquerque, NM, USA: Applied Research Associates, Inc., (www.ara.com).
   Google Scholar
• Auttachoat W, McLoughlin CE, White KL, Jr., Smith MJ. 2014. Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles. J Immunotoxicol 11:273–82.
   PubMed Web of Science ®Google Scholar
• Carlander U, Li D, Jolliet O, Emond C, Johanson G. 2016. Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles. Int J Nanomed 11:625–40.
   PubMed Web of Science ®Google Scholar
• Choi HS, Liu W, Misra P, Tanaka E, Zimmer JP, Ipe BI, et al. 2007. Renal clearance of quantum dots. Nat Biotechnol 25:1165–70.
   PubMed Web of Science ®Google Scholar
• Christensen FM, Johnston HJ, Stone V, Aitken RJ, Hankin S, Peters S, Aschberger K. 2011. Nano-TiO(2) – feasibility and challenges for human health risk assessment based on open literature. Nanotoxicology 5:110–24.
   PubMed Web of Science ®Google Scholar
• Fabian E, Landsiedel R, Ma-Hock L, Wiench K, Wohlleben W, Van Ravenzwaay B. 2008. Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats. Arch Toxicol 82:151–7.
   PubMed Web of Science ®Google Scholar
• Geiser M, Casaulta M, Kupferschmid B, Schulz H, Semmler-Behnke M, Kreyling W. 2008. The role of macrophages in the clearance of inhaled ultrafine titanium dioxide particles. Am J Respir Cell Mol Biol 38:371–6.
   PubMed Web of Science ®Google Scholar
• Geiser M, Rothen-Rutishauser B, Kapp N, Schurch S, Kreyling W, Schulz H, et al. 2005. Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 113:1555–60.
   PubMed Web of Science ®Google Scholar
• Geraets L, Oomen AG, Krystek P, Jacobsen NR, Wallin H, Laurentie M, et al. 2014. Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats. Part Fibre Toxicol 11:30.
   PubMed Web of Science ®Google Scholar
• Gontier E, Ynsa M-D, Bíró T, Hunyadi J, Kiss B, Gáspár K, et al. 2008. Is there penetration of titania nanoparticles in sunscreens through skin? A comparative electron and ion microscopy study. Nanotoxicology 2:218–31.
   Web of Science ®Google Scholar
• Gu Z, Rolfe BE, Thomas AC, Xu ZP. 2013. Restenosis treatments using nanoparticle-based drug delivery systems. Curr Pharm Des 19:6330–9.
   PubMed Web of Science ®Google Scholar
• Hirn S, Semmler-Behnke M, Schleh C, Wenk A, Lipka J, Schaffler M, et al. 2011. Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration. Eur J Pharm Biopharm 77:407–16.
   PubMed Web of Science ®Google Scholar
• Hume DA. 2008. Differentiation and heterogeneity in the mononuclear phagocyte system. Mucosal Immunol 1:432–41.
   PubMed Web of Science ®Google Scholar
• Jani P, Halbert GW, Langridge J, Florence AT. 1990. Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency. J Pharm Pharmacol 42:821–6.
   PubMed Web of Science ®Google Scholar
• Jia L, Xu M, Zhen W, Shen X, Zhu Y, Wang W, Wang X. 2008. Novel anti-oxidative role of calreticulin in protecting A549 human type II alveolar epithelial cells against hypoxic injury. Am J Physiol Cell Physiol 294:C47–55.
   PubMed Web of Science ®Google Scholar
• Kreyling WG, Biswas P, Messing ME, Gibson N, Geiser M, Wenk A, et al. 2011. Generation and characterization of stable, highly concentrated titanium dioxide nanoparticle aerosols for rodent inhalation studies. J Nanopart Res 13:511–24.
   Web of Science ®Google Scholar
• Kreyling WG, Hirn S, Moller W, Schleh C, Wenk A, Celik G, et al. 2014. Air-blood barrier translocation of tracheally instilled gold nanoparticles inversely depends on particle size. ACS Nano 8:222–33.
   PubMed Web of Science ®Google Scholar
• Kreyling WG, Holzwarth U, Haberl N, Kozempel J, Wenk A, Hirn S, et al. 2017a. Quantitative biokinetics of titanium dioxide nanoparticles after intratracheal instillation in rats (Part 3). Nanotoxicology. [Epub ahead of print]. doi: 10.1080/17435390.2017.1306894
   Web of Science ®Google Scholar
• Kreyling WG, Holzwarth U, Schleh C, Kozempel J, Wenk A, Haberl N, et al. 2017b. Quantitative biokinetics of titanium dioxide nanoparticles after oral application in rats (Part 2). Nanotoxicology. [Epub ahead of print]. doi: 10.1080/17435390.2017.1306893
   Web of Science ®Google Scholar
• Kreyling WG, Semmler M, Erbe F, Mayer P, Takenaka S, Schulz H, et al. 2002. Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low. J Toxicol Environ Health A 65:1513–30.
   PubMed Web of Science ®Google Scholar
• Kreyling WG, Semmler-Behnke M, Takenaka S, Moller W. 2013. Differences in the biokinetics of inhaled nano- versus micrometer-sized particles. Acc Chem Res 46:714–22.
   PubMed Web of Science ®Google Scholar
• Li N, Xia T, Nel AE. 2008. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic Biol Med 44:1689–99.
   PubMed Web of Science ®Google Scholar
• Lomer MC, Hutchinson C, Volkert S, Greenfield SM, Catterall A, Thompson RP, Powell JJ. 2004. Dietary sources of inorganic microparticles and their intake in healthy subjects and patients with Crohn's disease. Br J Nutr 92:947–55.
   PubMed Web of Science ®Google Scholar
• Louro H, Tavares A, Vital N, Costa PM, Alverca E, Zwart E, et al. 2014. Integrated approach to the in vivo genotoxic effects of a titanium dioxide nanomaterial using LacZ plasmid-based transgenic mice. Environ Mol Mutagen 55:500–9.
   PubMed Web of Science ®Google Scholar
• Matusiewicz H. 2014. Potential release of in vivo trace metals from metallic medical implants in the human body: from ions to nanoparticles – a systematic analytical review. Acta Biomater 10:2379–403.
   PubMed Web of Science ®Google Scholar
• Morimoto Y, Kobayashi N, Shinohara N, Myojo T, Tanaka I, Nakanishi J. 2010. Hazard assessments of manufactured nanomaterials. J Occup Health 52:325–34.
   PubMed Web of Science ®Google Scholar
• Ninomiya K, Fukuda A, Ogino C, Shimizu N. 2014. Targeted sonocatalytic cancer cell injury using avidin-conjugated titanium dioxide nanoparticles. Ultrason Sonochem 21:1624–8.
   PubMed Web of Science ®Google Scholar
• Oeff K, Konig A. 1955. Blood volume of rat organs and residual amount of blood after blood letting or irrigation; determination with radiophosphorus-labeled erythrocytes. Naunyn-Schmiedebergs Archiv Exp Pathol Pharmakol 226:98–102.
   PubMedGoogle Scholar
• Patri A, Umbreit T, Zheng J, Nagashima K, Goering P, Francke-Carroll S, et al. 2009. Energy dispersive X-ray analysis of titanium dioxide nanoparticle distribution after intravenous and subcutaneous injection in mice. J Appl Toxicol 29:662–72.
   PubMed Web of Science ®Google Scholar
• Peters RJ, Van Bemmel G, Herrera-Rivera Z, Helsper JP, Marvin HJ, Weigel S, et al. 2014. Characterisation of titanium dioxide nanoparticles in food products: analytical methods to define nanoparticles. J Agric Food Chem 62:6285–93.
   PubMed Web of Science ®Google Scholar
• Rinderknecht A, Prudhomme R, Poreda R, Gelein R, Corson N, Pidruczny A, et al. 2008. Biokinetics of Au nanoparticles relative to size surface coating and portal of entry. 47th Annual Society of Toxicology Meeting, Seattle, WA.
   Google Scholar
• Sadauskas E, Danscher G, Stoltenberg M, Vogel U, Larsen A, Wallin H. 2009. Protracted elimination of gold nanoparticles from mouse liver. Nanomedicine 5:162–9.
   PubMed Web of Science ®Google Scholar
• Schleh C, Semmler-Behnke M, Lipka J, Wenk A, Hirn S, Schaffler M, et al. 2012. Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration. Nanotoxicology 6:36–46.
   PubMed Web of Science ®Google Scholar
• Semmler M, Seitz J, Erbe F, Mayer P, Heyder J, Oberdörster G, Kreyling WG. 2004. Long-term clearance kinetics of inhaled ultrafine insoluble iridium particles from the rat lung, including transient translocation into secondary organs. Inhal Toxicol 16:453–9.
   PubMed Web of Science ®Google Scholar
• Semmler-Behnke M, Takenaka S, Fertsch S, Wenk A, Seitz J, Mayer P, et al. 2007. Efficient elimination of inhaled nanoparticles from the alveolar region: evidence for interstitial uptake and subsequent reentrainment onto airways epithelium. Environ Health Perspect 115:728–33.
   PubMed Web of Science ®Google Scholar
• Setyawati MI, Tay CY, Chia SL, Goh SL, Fang W, Neo MJ, et al. 2013. Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin. Nat Commun 4:1673.
   PubMed Web of Science ®Google Scholar
• Shi H, Magaye R, Castranova V, Zhao J. 2013. Titanium dioxide nanoparticles: a review of current toxicological data. Part Fibre Toxicol 10:15.
   PubMed Web of Science ®Google Scholar
• Vogelsberger W, Schmidt J, Roelfs F. 2008. Dissolution kinetics of oxide nanoparticles: the observation of an unusual behaviour. Colloids Surf A 324:51–7.
   Web of Science ®Google Scholar
• Wang T, Jiang H, Wan L, Zhao Q, Jiang T, Wang B, Wang S. 2015. Potential application of functional porous TiO2 nanoparticles in light-controlled drug release and targeted drug delivery. Acta Biomater 13:354–63.
   PubMed Web of Science ®Google Scholar
• Weir A, Westerhoff P, Fabricius L, Hristovski K, Von Goetz N. 2012. Titanium dioxide nanoparticles in food and personal care products. Environ Sci Technol 46:2242–50.
   PubMed Web of Science ®Google Scholar
• Xie GP, Wang C, Sun J, Zhong GR. 2011. Tissue distribution and excretion of intravenously administered titanium dioxide nanoparticles. Toxicol Lett 205:55–61.
   PubMed Web of Science ®Google Scholar
• Yamashita K, Yoshioka Y, Higashisaka K, Mimura K, Morishita Y, Nozaki M, et al. 2011. Silica and titanium dioxide nanoparticles cause pregnancy complications in mice. Nat Nanotechnol 6:321–8.
   PubMed Web of Science ®Google Scholar
• Zarschler K, Rocks L, Licciardello N, Boselli L, Polo E, Garcia KP, et al. 2016. Ultrasmall inorganic nanoparticles: state-of-the-art and perspectives for biomedical applications. Nanomedicine 12:1663–701.
   PubMed Web of Science ®Google Scholar