991
Views
33
CrossRef citations to date
0
Altmetric
Original Article

Acute in vitro and in vivo toxicity of a commercial grade boron nitride nanotube mixture

, , , , , , , , , , , , , , & show all
Pages 1040-1058 | Received 23 May 2017, Accepted 03 Oct 2017, Published online: 02 Nov 2017

References

  • Aragon, M. J., L. Topper, C. R. Tyler, B. Sanchez, K. Zychowski, T. Young, G. Herbert, et al. 2017. “Serum-Borne Bioactivity Caused by Pulmonary Multiwalled Carbon Nanotubes Induces Neuroinflammation via Blood–Brain Barrier Impairment.” Proceedings of the National Academy of Sciences 114: E1968–E1976.
  • Aragon, M., A. Erdely, L. Bishop, R. Salmen, J. Weaver, J. Liu, P. Hall, et al. 2016. “MMP-9-Dependent Serum-Borne Bioactivity Caused by Multiwalled Carbon Nanotube Exposure Induces Vascular Dysfunction via the CD36 Scavenger Receptor.” Toxicological Sciences 150: 488–498.
  • ATSDR. 2010. Toxicological profile for Boron. In: U.S. Department of Health and Human Services, PHS ed. Atlanta, GA: Agency for Toxic Substances and Disease Registry.
  • Bergsbaken, T., S. L. Fink, and B. T. Cookson. 2009. “Pyroptosis: Host Cell Death and Inflammation.” Nature Reviews Microbiology 7: 99–109.
  • Bishop, L., L. Cena, M. Orandle, N. Yanamala, M. M. Dahm, M. E. Birch, D. E. Evans, et al. 2017. “In Vivo Toxicity Assessment of Occupational Components of the Carbon Nanotube Life Cycle To Provide Context to Potential Health Effects.” ACS Nano 11: 8849–8863.
  • Cassel, S. L., S. C. Eisenbarth, S. S. Iyer, J. J. Sadler, O. R. Colegio, L. A. Tephly, A. B. Carter, et al. 2008. “The Nalp3 Inflammasome is Essential for the Development of Silicosis.” Proceedings of the National Academy of Sciences of the United States of America 105: 9035–9040.
  • Chen, B. T., D. Schwegler-Berry, W. McKinney, S. Stone, J. L. Cumpston, S. Friend, D. W. Porter, et al. 2012. “Multi-Walled Carbon Nanotubes: Sampling Criteria and Aerosol Characterization.” Inhalation Toxicology 24: 798–820.
  • Chen, X., P. Wu, M. Rousseas, D. Okawa, Z. Gartner, and C. R. Bertozzi. 2009. “Boron Nitride Nanotubes are Noncytotoxic and can be Functionalized for Interaction with Proteins and Cells.” Journal of the American Chemical Society 131: 890–891.
  • Ciofani, G., S. Danti, D. D’Alessandro, S. Moscato, and A. Menciassi. 2010. “Assessing Cytotoxicity of Boron Nitride Nanotubes: Interference with the MTT Assay.” Biochemical and Biophysical Research Communications 394: 405–411.
  • Cohen, J. M., J. G. Teeguarden, and P. Demokritou. 2014. “An Integrated Approach for the In Vitro Dosimetry of Engineered Nanomaterials.” Particle and Fibre Toxicology 11: 20.
  • Dahm, M. M., M. K. Schubauer-Berigan, D. E. Evans, M. E. Birch, J. E. Fernback, and J. A. Deddens. 2015. “Carbon Nanotube and Nanofiber Exposure Assessments: An Analysis of 14 Site Visits.” Annals of Occupational Hygiene 59: 705–723.
  • DeLoid, G. M., J. M. Cohen, G. Pyrgiotakis, and P. Demokritou. 2017. “Preparation, Characterization, and In Vitro Dosimetry of Dispersed, Engineered Nanomaterials.” Nature Protocols 12: 355–371.
  • Dong, J., and Q. Ma. 2015. “Advances in Mechanisms and Signaling Pathways of Carbon Nanotube Toxicity.” Nanotoxicology 9: 658–676.
  • Dostert, C., V. Pétrilli, R. Van Bruggen, C. Steele, B. T. Mossman, and J. Tschopp. 2008. “Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica.” Science (New York, N.Y.) 320: 674–677.
  • Duan, J., V. K. Kodali, M. J. Gaffrey, J. Guo, R. K. Chu, D. G. Camp, R. D. Smith, et al. 2015. “Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-Dependent Regulation of Macrophage Function during Nanoparticle-Induced Oxidative Stress.” ACS Nano 10: 524–538.
  • Erdely, A., M. Dahm, B. T. Chen, P. C. Zeidler-Erdely, J. E. Fernback, M. E. Birch, D. E. Evans, et al. 2013. “Carbon Nanotube Dosimetry: From Workplace Exposure Assessment to Inhalation Toxicology.” Particle and Fibre Toxicology 10: 53.
  • Erdely, A., M. M. Dahm, M. K. Schubauer-Berigan, B. T. Chen, J. M. Antonini, and M. D. Hoover. 2016. “Bridging the gap between exposure assessment and inhalation toxicology: Some insights from the carbon nanotube experience.” Journal of Aerosol Science 99: 157–162.
  • Erdely, A., T. Hulderman, R. Salmen, A. Liston, P. C. Zeidler-Erdely, D. Schwegler-Berry, V. Castranova, et al. 2009. “Cross-Talk Between Lung and Systemic Circulation During Carbon Nanotube Respiratory Exposure.” Potential Biomarkers. Nano Letters 9: 36–43.
  • Ferreira, T. H., P. Silva, R. Santos, and E. Sousa. 2011. “A Novel Synthesis Route to Produce Boron Nitride Nanotubes for Bioapplications.” Journal of Biomaterials and Nanobiotechnology 2: 426.
  • Ge, C., Y. Li, J. J. Yin, Y. Liu, L. Wang, Y. Zhao, and C. Chen. 2012. “The Contributions of Metal Impurities and Tube Structure to the Toxicity of Carbon Nanotube Materials.” NPG Asia Materials 4: e32.
  • Godwin, H., C. Nameth, D. Avery, L. L. Bergeson, D. Bernard, E. Beryt, W. Boyes, et al. 2015. “Nanomaterial Categorization for Assessing Risk Potential to Facilitate Regulatory Decision-Making.” ACS Nano 9: 3409–3417.
  • Guo, H., J. B. Callaway, and J. P. Ting. 2015. “Inflammasomes: Mechanism of Action, Role in Disease, and Therapeutics.” Nature Medicine 21: 677–687.
  • Hamilton, R. F., Z. Wu, S. Mitra, P. K. Shaw, and A. Holian. 2013. “Effect of MWCNT Size, Carboxylation, and Purification on In Vitro and In Vivo Toxicity, Inflammation and Lung Pathology.” Particle and Fibre Toxicology 10.
  • Hinderliter, P. M., K. R. Minard, G. Orr, W. B. Chrisler, B. D. Thrall, J. G. Pounds, and J. G. Teeguarden. 2010. “ISDD: A Computational Model of Particle Sedimentation, Diffusion and Target Cell Dosimetry for In Vitro Toxicity Studies.” Particle and Fibre Toxicology 7: 36.
  • Horvath, L., A. Magrez, D. Golberg, C. Zhi, Y. Bando, R. Smajda, E. Horvath, et al. 2011. “In Vitro Investigation of the Cellular Toxicity of Boron Nitride Nanotubes.” ACS Nano 5:3800–3810.
  • Jensen, A. A. 2009. “Risk Assessment of Boron in Glass Wool Insulation.” Environmental Science and Pollution Research International 16: 73–78.
  • Jiang, Y., H. Zhang, Y. Wang, M. Chen, S. Ye, Z. Hou, and L. Ren. 2013. “Modulation of Apoptotic Pathways of Macrophages by Surface-Functionalized Multi-Walled Carbon Nanotubes.” PLoS One 8: e65756.
  • Johnston, H. J., G. R. Hutchison, F. M. Christensen, S. Peters, S. Hankin, K. Aschberger, and V. Stone. 2010. “A Critical Review of the Biological Mechanisms Underlying the In Vivo and In Vitro Toxicity of Carbon Nanotubes: The Contribution of Physico-Chemical Characteristics.” Nanotoxicology 4: 207–246.
  • Kodali, V., and B. D. Thrall. 2015. “Oxidative Stress and Nanomaterial-Cellular Interactions.” In: Studies on Experimental Toxicology and Pharmacology, edited by M. S. Roberts, P. J. Kehrer, and L.-O. Klotz, 347–367. Cham: Springer International Publishing.
  • Kodali, V., M. H. Littke, S. C. Tilton, J. G. Teeguarden, L. Shi, C. W. Frevert, W. Wang, et al. 2013. “Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles.” ACS Nano 7: 6997–7010.
  • Kuempel, E. D., V. Castranova, C. L. Geraci, and P. A. Schulte. 2012. “Development of Risk-Based Nanomaterial Groups for Occupational Exposure Control.” Journal of Nanoparticle Research 14: 1029.
  • Labib, S., A. Williams, C. L. Yauk, J. K. Nikota, H. Wallin, U. Vogel, S. Halappanavar. 2016. “Nano-Risk Science: Application of Toxicogenomics in an Adverse Outcome Pathway Framework for Risk Assessment of Multi-Walled Carbon Nanotubes.” Particle and Fibre Toxicology 13:15.
  • Mercer, R. R., J. F. Scabilloni, A. F. Hubbs, L. A. Battelli, W. McKinney, S. Friend, M. G. Wolfarth, et al. 2013. “Distribution and Fibrotic Response Following Inhalation Exposure to Multi-Walled Carbon Nanotubes.” Particle and Fibre Toxicology 10: 33.
  • Miao, E. A., J. V. Rajan, and A. Aderem. 2011. “Caspase‐1‐Induced Pyroptotic Cell Death.” Immunological Reviews 243: 206–214.
  • National Research Council. 2011. Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academies Press.
  • NIH. 1986. Public Health Service Policy on Humane Care and Use of Laboratory Animals. Bethesda, MD: National Institutes of Health (U.S.A).
  • NIOSH. 2013. Current Intelligence Bulletin 65: Occupational Exposure to Carbon Nanotubes and Nanofibers. DHHS (NIOSH) Publication.
  • Nymark, P., P. Wijshoff, R. Cavill, M. van Herwijnen, M. L. Coonen, S. Claessen, J. Catalán, et al. 2015. “Extensive Temporal Transcriptome and MicroRNA Analyses Identify Molecular Mechanisms Underlying Mitochondrial Dysfunction Induced by Multi-Walled Carbon Nanotubes in Human Lung Cells.” Nanotoxicology 9: 624–635.
  • Oberdörster, G., V. Castranova, B. Asgharian, and P. Sayre. 2015. “Inhalation Exposure to Carbon Nanotubes (CNT) and Carbon Nanofibers (CNF): Methodology and Dosimetry.” Journal of Toxicology and Environmental Health, Part B 18: 121–212.
  • Pope, C III. 2000. “Epidemiology of Fine Particulate Air Pollution and Human Health: Biologic Mechanisms and Who's at Risk?” Environmental Health Perspectives 108: 713.
  • Porter, D. W., A. F. Hubbs, B. T. Chen, W. McKinney, R. R. Mercer, M. G. Wolfarth, L. Battelli, et al. 2012. “Acute Pulmonary Dose–Responses to Inhaled Multi-Walled Carbon Nanotubes.” Nanotoxicology 7: 1179–1194.
  • Porter, D. W., A. F. Hubbs, R. R. Mercer, N. Wu, M. G. Wolfarth, K. Sriram, S. Leonard, et al. 2010. “Mouse Pulmonary Dose-and Time Course-Responses Induced by Exposure to Multi-Walled Carbon Nanotubes.” Toxicology 269: 136–147.
  • Porter, D., K. Sriram, M. Wolfarth, A. Jefferson, D. Schwegler-Berry, M. E. Andrew, and V. Castranova. 2008. “A Biocompatible Medium for Nanoparticle Dispersion.” Nanotoxicology 2: 144–154.
  • Rasel, M. A. I., T. Li, T. D. Nguyen, S. Singh, Y. Zhou, Y. Xiao, and Y. Gu. 2015. “Biophysical Response of Living Cells to Boron Nitride Nanoparticles: Uptake Mechanism and Bio-Mechanical Characterization.” Journal of Nanoparticle Research 17: 441.
  • Rocca, A., A. Marino, S. Del Turco, V. Cappello, P. Parlanti, M. Pellegrino, D. Golberg, et al. 2016. “Pectin-Coated Boron Nitride Nanotubes: In vitro Cyto-/Immune-Compatibility on RAW 264.7 Macrophages.” Biochimica Et Biophysica Acta (BBA)-General Subjects 1860: 775–784.
  • Roco, M. C., C. A. Mirkin, and M. C. Hersam. 2011. Nanotechnology Research Directions for Societal Needs in 2020: Retrospective and Outlook. New York: Springer Science & Business Media.
  • Roig-Navarro, A. F., F. J. López, R. Serrano, and F. Hernández. 1997. “An Assessment of Heavy Metals and Boron Contamination in Workplace Atmospheres from Ceramic Factories.” Science of the Total Environment 201: 225–234.
  • Sargent, L. M., D. W. Porter, L. M. Staska, A. F. Hubbs, D. T. Lowry, L. Battelli, K. J. Siegrist, et al. 2014. “Promotion of Lung Adenocarcinoma Following Inhalation Exposure to Multi-Walled Carbon Nanotubes.” Particle and Fibre Toxicology 11: 3.
  • Schwartz, J., D. W. Dockery, and L. M. Neas. 1996. “Is Daily Mortality Associated Specifically with Fine Particles?” Journal of the Air and Waste Management Association 46: 927–939.
  • Shvedova, A. A., A. Pietroiusti, B. Fadeel, and V. E. Kagan. 2012. “Mechanisms of Carbon Nanotube-Induced Toxicity: Focus on Oxidative Stress.” Toxicology and Applied Pharmacology 261: 121–133.
  • Smith, M. W., K. C. Jordan, C. Park, J. W. Kim, P. T. Lillehei, R. https://doi.org/Crooks, and J. S. https://doi.org/Harrison. 2009. “Very Long Single-and Few-Walled Boron Nitride Nanotubes Via the Pressurized Vapor/Condenser Method.” Nanotechnology 20: 505604.
  • Stern, S. T., P. P. Adiseshaiah, and R. M. Crist. 2012. “Autophagy and Lysosomal Dysfunction as Emerging Mechanisms of Nanomaterial Toxicity.” Particle and Fibre Toxicology 9: 20.
  • Stone, K. C., R. R. Mercer, B. A. Freeman, L.-Y. Chang, and J. D. Crapo. 1992. “Distribution of Lung Cell Numbers and Volumes Between Alveolar and Nonalveolar Tissue.” American Review of Respiratory Disease 146: 454–456.
  • Sun, B., X. Wang, Z. Ji, M. Wang, Y. P. Liao, C. H. Chang, R. Li, et al. 2015. “NADPH Oxidase‐Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes.” Small 11: 2087–2097.
  • Sun, B., X. Wang, Z. Ji, R. Li, and T. Xia. 2013. “NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials.” Small 9: 1595–1607.
  • Sunderkötter, C., K. Steinbrink, M. Goebeler, R. Bhardwaj, and C. Sorg. 1994. “Macrophages and Angiogenesis.” Journal of Leukocyte Biology 55: 410–422.
  • Tsuruoka, S., F. R. Cassee, and V. Castranova. 2013a. “A New Approach to Design Safe CNTs with an Understanding of Redox Potential.” Particle and Fibre Toxicology 10: 44.
  • Tsuruoka, S., K. Takeuchi, K. Koyama, T. Noguchi, M. Endo, F. Tristan, M. Terrones, et al. 2013b. “ROS Evaluation for a Series of CNTs and their Derivatives using an ESR Method with DMPO.” Journal of Physics: Conference Series 429: 12029.
  • Vietti, G., D. Lison, and S. van den Brule. 2016. “Mechanisms of Lung Fibrosis Induced by Carbon Nanotubes: Towards an Adverse Outcome Pathway (AOP).” Particle and Fibre Toxicology 13:11.
  • Villeneuve, D. L., D. Crump, N. Garcia-Reyero, M. Hecker, T. H. Hutchinson, C. A. LaLone, B. Landesmann, et al. 2014. “Adverse Outcome Pathway (AOP) Development I: Strategies and Principles.” Toxicological Sciences 142:312–320.
  • Wang, L., V. Castranova, A. Mishra, B. Chen, R. R. Mercer, D. Schwegler-Berry, and Y. Rojanasakul. 2010. “Dispersion of Single-Walled Carbon Nanotubes by a Natural Lung Surfactant for Pulmonary In Vitro and In Vivo Toxicity Studies.” Particle and Fibre Toxicology 7: 31.
  • Wegman, D. H., E. A. Eisen, X. Hu, S. R. Woskie, R. G. Smith, and D. H. Garabrant. 1994. “Acute and Chronic Respiratory Effects of Sodium Borate Particulate Exposures.” Environmental Health Perspectives 102: 119–128.
  • Wilding, J. L., W. J. Smith, P. Yevich, M. E. Sicks, S. G. Ryan, and C. L. Punte. 1959. “The Toxicity of Boron Oxide.” American Industrial Hygiene Association Journal 20: 284–289.
  • Xia, T., R. F. Hamilton, Jr., J. C. Bonner, E. D. Crandall, A. Elder, F. Fazlollahi, T. A. Girtsman, et al. 2013. “Interlaboratory Evaluation of In Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium.” Environmental Health Perspectives 121: 683.
  • Zeidler-Erdely, P. C., A. Erdely, and J. M. Antonini. 2012. “Immunotoxicology of Arc Welding Fume: Worker and Experimental Animal Studies.” Journal of Immunotoxicology 9: 411–425.
  • Zhang, H., Z. Ji, T. Xia, H. Meng, C. Low-Kam, R. Liu, S. Pokhrel, et al. 2012. “Use of Metal Oxide Nanoparticle Band Gap to Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation.” ACS Nano 6: 4349–4368.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.