16
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Tocopherol-human serum albumin nanoparticles enhance lapatinib delivery and overcome doxorubicin resistance in breast cancer

, , & ORCID Icon
Received 19 Mar 2024, Accepted 21 May 2024, Published online: 02 Jul 2024

References

  • Pondé N, Brandão M, El-Hachem G, et al. Treatment of advanced HER2-positive breast cancer: 2018 and beyond. Cancer Treat Rev. W.B. Saunders Ltd; 2018;10–20. doi:10.1016/j.ctrv.2018.04.016
  • Breast Cancer [Internet]. [ Cited 2024 Mar 18]. Available from: https://www.bcrf.org/blog/her2-positive-breast-cancer-treatment-research/
  • Bredin P, Walshe JM, Denduluri N. Systemic therapy for metastatic HER2-positive breast cancer. Semin Oncol. W.B. Saunders 2020;47(5):259–269.
  • Collins DM, Madden SF, Gaynor N, et al. Effects of HER family-targeting tyrosine kinase inhibitors on antibody-dependent cell-mediated cytotoxicity in HER2-expressing breast cancer. Clin Cancer Res. 2021;27:807–818. doi:10.1158/1078-0432.CCR-20-2007
  • Ma F, Ouyang Q, Li W, et al. Pyrotinib or Lapatinib combined with Capecitabine in HER2-positive metastatic breast cancer with prior taxanes, anthracyclines, and/ or trastuzumab: a randomized, phase II Study. J Clin Oncol. 2019;37(29). doi: 10.1200/JCO.19
  • D Johnston SR, Hegg R, Im S-A, et al. Phase III, randomized study of dual human epidermal growth factor receptor 2 (HER2) blockade with lapatinib plus trastuzumab in combination with an aromatase inhibitor in postmenopausal women with HER2-positive, hormone receptor-positive metastatic breast cancer: updated results of ALTERNATIVE. J Clin Oncol. 2020;38(1). doi:10.1200/JCO.20
  • Bischoff J, Barinoff J, Mundhenke C, et al. A randomized phase II study to determine the efficacy and tolerability of two doses of eribulin plus lapatinib in trastuzumab-pretreated patients with HER-2-positive metastatic breast cancer (E-VITA). Anticancer Drugs. 2019;30:394–401. doi:10.1097/CAD.0000000000000722
  • Kunte S, Abraham J, Montero AJ. Novel HER2–targeted therapies for HER2–positive metastatic breast cancer. Cancer. John Wiley and Sons Inc; 2020;4278–4288. doi:10.1002/cncr.33102
  • Bonde GV, Yadav SK, Chauhan S, et al. Lapatinib nano-delivery systems: a promising future for breast cancer treatment. Expert Opin Drug Deliv. Taylor and Francis Ltd; 2018;495–507. doi:10.1080/17425247.2018.1449832
  • Das S, Paul M, Ghosh B, et al. Synergistic anticancer response via docetaxel- and oleanolic acid-loaded albumin/poly(lactide) nanoparticles in triple-negative breast cancer. ACS Appl Nano Mater. 2023;6:19710–19726. doi:10.1021/acsanm.3c03499
  • Parodi A, Miao J, Soond SM, Rudzińska M, Zamyatnin AA. Albumin nanovectors in cancer therapy and imaging. Biomolecules. 2019;9(6):218. doi:10.3390/biom9060218
  • Itoo AM, Paul M, Ghosh B, Biswas S. Oxaliplatin delivery via chitosan/vitamin E conjugate micelles for improved efficacy and MDR-reversal in breast cancer. Carbohydr Polym. 2022;282. doi:10.1016/j.carbpol.2022.119108 .
  • Zeeshan F, Madheswaran T, Panneerselvam J, et al. Human serum albumin as multifunctional nanocarrier for cancer therapy. J Pharm Sci. Elsevier B.V. 2021;3111–3117. doi:10.1016/j.xphs.2021.05.001
  • Larsen MT, Kuhlmann M, Hvam ML, Howard KA. Albumin-based drug delivery: harnessing nature to cure disease. Mol Cell Ther. 2016;4(1). doi:10.1186/s40591-016-0048-8
  • Kumari P, Ghosh B, Biswas S. Nanocarriers for cancer-targeted drug delivery. J Drug Target. Taylor and Francis Ltd; 2016;179–191. doi:10.3109/1061186X.2015.1051049
  • Kumari P, Paul M, Bobde Y, et al. Albumin-based lipoprotein nanoparticles for improved delivery and anticancer activity of curcumin for cancer treatment. Nanomedicine. 2020;15:2851–2869. doi:10.2217/nnm-2020-0232
  • Abraham A, Kattoor AJ, Saldeen T, et al. Vitamin E and its anticancer effects. Crit Rev Food Sci Nutr. Taylor and Francis Inc.; 2019;2831–2838. doi:10.1080/10408398.2018.1474169
  • Gorain B, Choudhury H, Pandey M, et al. Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy. Mater Sci Engin. 2018;91:868–880. doi:10.1016/j.msec.2018.05.054
  • Duhem N, Danhier F, Préat V. Vitamin E-based nanomedicines for anti-cancer drug delivery. J Control Rel. 2014;182:33–44. doi:10.1016/j.jconrel.2014.03.009
  • Voigtlaender M, Schneider-Merck T, Trepel M. Lapatinib. Recent results in cancer research. Springer New York LLC. 2018;211:19–44. doi:10.1007/978-3-319-91442-8_2
  • Mu Y, Sun D. Lapatinib, a dual inhibitor of epidermal growth factor receptor (EGFR) and HER-2, enhances radiosensitivity in mouse bladder tumor line-2 (MBT-2) cells in vitro and in vivo. Med Sci Monitor. 2018;24:5811–5819. doi:10.12659/MSM.909865
  • Kwon YS, Chun SY, Nam KS, et al. Lapatinib sensitizes quiescent MDA-MB-231 breast cancer cells to doxorubicin by inhibiting the expression of multidrug resistance-associated protein-1. Oncol Rep. 2015;34:884–890. doi:10.3892/or.2015.4047
  • Wan X, Zheng X, Pang X, et al. Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain. Oncotarget. 2016;7(23). doi:10.18632/oncotarget.8697
  • Wan X, Zheng X, Pang X, et al. The potential use of lapatinib-loaded human serum albumin nanoparticles in the treatment of triple-negative breast cancer. Rev Port Pneumol. 2002;8:131–138.
  • Kumbham S, Paul M, Itoo A, et al. Oleanolic acid-conjugated human serum albumin nanoparticles encapsulating doxorubicin as synergistic combination chemotherapy in oropharyngeal carcinoma and melanoma. Int J Pharm. 2022;614:121479. doi:10.1016/j.ijpharm.2022.121479
  • Paul M, Ghosh B, Biswas S, et al. Human serum albumin-oxaliplatin (Pt(IV)) prodrug nanoparticles with dual reduction sensitivity as effective nanomedicine for triple-negative breast cancer. Int J Biol Macromol. 2024;256: 128281.
  • Paramanantham A, Jung EJ, Kim HJ, et al. Doxorubicin-resistant tnbc cells exhibit rapid growth with cancer stem cell-like properties and emt phenotype, which can be transferred to parental cells through autocrine signaling. Int J Mol Sci. 2021;22(22). doi:10.3390/ijms222212438
  • Alkaraki A, Alshaer W, Wehaibi S, et al. Enhancing chemosensitivity of wild-type and drug-resistant MDA-MB-231 triple-negative breast cancer cell line to doxorubicin by silencing of STAT 3, Notch-1, and β-catenin genes. Breast Cancer. 2020;27:989–998. doi:10.1007/s12282-020-01098-9
  • Chakravarty G, Mathur A, Mallade P, et al. Nelfinavir targets multiple drug resistance mechanisms to increase the efficacy of doxorubicin in MCF-7/Dox breast cancer cells. Biochimie. 2016;124: 53–64.
  • Hekmat A, Salavati F, Hesami Tackallou S. The effects of paclitaxel in the combination of diamond nanoparticles on the structure of human serum albumin (HSA) and their antiproliferative role on MDA-MB-231 cells. Protein J. 2020;39:268–283. doi:10.1007/s10930-020-09882-4

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.