Pituitary dysfunction after traumatic brain injury: prevalence and screening strategies

References

• Dewan MC, Rattani A, Gupta S, et al. Estimating the global incidence of traumatic brain injury. J Neurosurg. 2018;27:1–18.
   Google Scholar
• Fama’ F, Vita R, Sindoni A, et al. High frequency of empty sella, with gender differences, in the early neuroradiology evaluation of patients with traumatic brain injury. A prospective study. J Clin Transl Endocrinol. 2018;15:54–61.
   PubMedGoogle Scholar
• Benvenga S. The history of pituitary dysfunction after traumatic brain injury. Pituitary. 2019;22(3):229–235.
   PubMed Web of Science ®Google Scholar
• Klose M, Feldt-Rasmussen U. Chronic endocrine consequences of traumatic brain injury - what is the evidence? Nat Rev Endocrinol. 2018;14(1):57–62.
   PubMed Web of Science ®Google Scholar
• Schneider HJ, Kreitschmann-Andermahr I, Ghigo E, et al. Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review. JAMA. 2007;298(12):1429–1438.
   PubMed Web of Science ®Google Scholar
• Lauzier F, Turgeon AF, Boutin A, et al. Clinical outcomes, predictors, and prevalence of anterior pituitary disorders following traumatic brain injury: a systematic review. Crit Care Med. 2014;42(3):712–721.
   PubMed Web of Science ®Google Scholar
• Emelifeonwu JA, Flower H, Loan JJ, et al. Prevalence of anterior pituitary dysfunction twelve months or more following traumatic brain injury in adults: a systematic review and meta-analysis. J Neurotrauma. 2020;37(2):217–226.
   PubMed Web of Science ®Google Scholar
• Hacioglu A, Kelestimur F, Tanriverdi F. Pituitary dysfunction due to sports-related traumatic brain injury. Pituitary. 2019;22(3):322–331.
   PubMed Web of Science ®Google Scholar
• Theadom A, Starkey NJ, Dowell T, et al. Sports-related brain injury in the general population: an epidemiological study. J Sci Med Sport. 2014;17(6):591–596.
   PubMed Web of Science ®Google Scholar
• Sarmiento K, Thomas KE, Daugherty J, et al. Emergency department visits for sports- and recreation-related traumatic brain injuries among children -united states, 2010-2016. MMWR Morb Mortal Wkly Rep. 2019;68(10):237–242.
   PubMed Web of Science ®Google Scholar
• Defense and Veterans Brain Injury Center (DVBIC). DoD worldwide numbers for TBI. Updated 2019; cited 2019; cited 2019 Apr 15. Avaliable from: https://dvbic.dcoe.mil/system/files/tbi-numbers/worldwide-totals-2000-2018Q1-total_jun-21-2018_v1.0_2018-07-26_0.pdf
   Google Scholar
• Harmon KG, Drezner JA, Gammons M, et al. American medical society for sports medicine position statement: concussion in sport [published correction appears in br j sports med. Br J Sports Med. 2013 Feb;47(3):184. 2013;47(1):15-26.
   Google Scholar
• Wilkinson CW, Pagulayan KF, Petrie EC, et al. High prevalence of chronic pituitary and target-organ hormone abnormalities after blast-related mild traumatic brain injury. Front Neurol. 2012;3:11.
   PubMedGoogle Scholar
• Baxter D, Sharp DJ, Feeney C, et al. Pituitary dysfunction after blast traumatic brain injury: the UK BIOSAP study. Ann Neurol. 2013;74(4):527–536.
   PubMed Web of Science ®Google Scholar
• Undurti A, Colasurdo EA, Sikkema CL, et al. Chronic hypopituitarism associated with increased postconcussive symptoms is prevalent after blast-induced mild traumatic brain injury. Front Neurol. 2018;9:72.
   PubMed Web of Science ®Google Scholar
• Ciarlone SL, Statz JK, Goodrich JA, et al. Neuroendocrine function and associated mental health outcomes following mild traumatic brain injury in OEF-deployed service members. J Neurosci Res. 2020;98(6):1174–1187.
   PubMed Web of Science ®Google Scholar
• Klose M, Juul A, Struck J, et al. Acute and long-term pituitary insufficiency in traumatic brain injury: a prospective single-centre study. Clin Endocrinol (Oxf). 2007;67(4):598–606.
   PubMed Web of Science ®Google Scholar
• Wagner AK, McCullough EH, Niyonkuru C, et al. Acute serum hormone levels: characterization and prognosis after severe traumatic brain injury. J Neurotrauma. 2011;28(6):871–888.
   PubMed Web of Science ®Google Scholar
• Prasanna KL, Mittal RS, Gandhi A. Neuroendocrine dysfunction in acute phase of moderate-to severe traumatic brain injury: a prospective study. Brain Inj. 2015;29(3):336–342.
   PubMed Web of Science ®Google Scholar
• Kleindienst A, Brabant G, Bock C, et al. Neuroendocrine function following traumatic brain injury and subsequent intensive care treatment: a prospective longitudinal evaluation. J Neurotrauma. 2009;26(9):1435–1446.
   PubMed Web of Science ®Google Scholar
• Dimopoulou I, Tsagarakis S, Kouyialis AT, et al. Hypothalamic-pituitary-adrenal axis dysfunction in critically ill patients with traumatic brain injury: incidence, pathophysiology, and relationship to vasopressor dependence and peripheral interleukin-6 levels. Crit Care Med. 2004;32(2):404‐8.
   PubMed Web of Science ®Google Scholar
• Dimopoulou I, Tsagarakis S, Theodorakopoulou M, et al. Endocrine abnormalities in critical care patients with moderate-to-severe head trauma: incidence, pattern and predisposing factors. Intensive Care Med. 2004;30(6):1051–1057.
   PubMed Web of Science ®Google Scholar
• Krahulik D, Zapletalova J, Frysak Z, et al. Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults. J Neurosurg. 2010;113(3):581–584.
   PubMed Web of Science ®Google Scholar
• Cohan P, Wang C, McArthur DL, et al. Acute secondary adrenal insufficiency after traumatic brain injury: a prospective study. Crit Care Med. 2005;33(10):2358–2366.
   PubMed Web of Science ®Google Scholar
• Hannon MJ, Crowley RK, Behan LA, et al. Acute glucocorticoid deficiency and diabetes insipidus are common after acute traumatic brain injury and predict mortality. J Clin Endocrinol Metab. 2013;98(8):3229–3237.
   PubMed Web of Science ®Google Scholar
• Bensalah M, Donaldson M, Aribi Y, et al. Cortisol evaluation during the acute phase of traumatic brain injury-A prospective study. Clin Endocrinol (Oxf). 2018;88(5):627–636.
   PubMed Web of Science ®Google Scholar
• Olivecrona Z, Dahlqvist P, Koskinen LO. Acute neuroendocrine profile and prediction of outcome after severe brain injury. Scand J Trauma Resusc Emerg Med. 2013;20(21):33.
   Google Scholar
• Alavi SA, Tan CL, Menon DK, et al. Incidence of pituitary dysfunction following traumatic brain injury: a prospective study from a regional neurosurgical centre. Br J Neurosurg. 2016;30(3):302‐6.
   PubMed Web of Science ®Google Scholar
• Agha A, Rogers B, Mylotte D, et al. Neuroendocrine dysfunction in the acute phase of traumatic brain injury. Clin Endocrinol (Oxf). 2004;60(5):584–591.
   PubMed Web of Science ®Google Scholar
• Agha A, Rogers B, Sherlock M, et al. Anterior pituitary dysfunction in survivors of traumatic brain injury. J Clin Endocrinol Metab. 2004;89(10):4929‐36.
   Web of Science ®Google Scholar
• Tölli A, Borg J, Bellander BM, et al. Pituitary function within the first year after traumatic brain injury or subarachnoid haemorrhage. J Endocrinol Invest. 2017;40(2):193–205.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, Senyurek H, Unluhizarci K, et al. High risk of hypopituitarism after traumatic brain injury: a prospective investigation of anterior pituitary function in the acute phase and 12 months after trauma. J Clin Endocrinol Metab. 2006;91(6):2105–2111.
   PubMed Web of Science ®Google Scholar
• Aimaretti G, Ambrosio MR, Di Somma C, et al. Residual pituitary function after brain injury-induced hypopituitarism: a prospective 12-month study. J Clin Endocrinol Metab. 2005;90(11):6085‐92.
   Web of Science ®Google Scholar
• Tanriverdi T, Ulutabanca H, Unluhizarci K, et al. Three years prospective investigation of anterior pituitary function after traumatic brain injury: a pilot study. Clin Endocrinol (Oxf). 2008;68(4):573–579.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, De Bellis A, Ulutabanca H, et al. A five year prospective investigation of anterior pituitary function after traumatic brain injury: is hypopituitarism long-term after head trauma associated with autoimmunity? J Neurotrauma. 2013 15;30(16):1426–1433.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, Unluhizarci K, Kocyigit I, et al. Brief communication: pituitary volume and function in competing and retired male boxers. Ann Intern Med. 2008;148(11):827–831.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, Unluhizarci K, Coksevim B, et al. Kickboxing sport as a new cause of traumatic brain injury-mediated hypopituitarism. Clin Endocrinol (Oxf). 2007;66(3):360–366.
   PubMed Web of Science ®Google Scholar
• Tandon A, Suri A, Kasliwal MK, et al. Assessment of endocrine abnormalities in severe traumatic brain injury: a prospective study. Acta Neurochir (Wien). 2009;151(11):1411–1417.
   PubMed Web of Science ®Google Scholar
• Lieberman SA, Oberoi AL, Gilkison CR, et al. Prevalence of neuroendocrine dysfunction in patients recovering from traumatic brain injury. J Clin Endocrinol Metab. 2001;86(6):2752‐56.
   PubMed Web of Science ®Google Scholar
• Nemes O, Kovacs N, Szujo S, et al. Can early clinical parameters predict post-traumatic pituitary dysfunction in severe traumatic brain injury? Acta Neurochir (Wien). 2016;158(12):2347‐53.
   PubMed Web of Science ®Google Scholar
• Agha A, Phillips J, O’Kelly P, et al. The Natural History of Post-Traumatic Hypopituitarism: implications for Assessment and Treatment. Am J Med. 2005;118(12):1416.
   PubMedGoogle Scholar
• Hackl JM, Gottardis M, Wieser C, et al. Endocrine abnormalities in severe traumatic brain injury–a cue to prognosis in severe craniocerebral trauma? Intensive Care Med. 1991;17(1):25–29.
   PubMed Web of Science ®Google Scholar
• Jeevanandam M, Holaday NJ, Petersen SR. Plasma levels of insulin-like growth factor binding protein-3 in acute trauma patients. Metabolism. 1995;44(9):1205–1208.
   PubMed Web of Science ®Google Scholar
• De Marinis L, Mancini A, Valle D, et al. Hypothalamic derangement in traumatized patients: growth hormone (GH) and prolactin response to thyrotrophin-releasing hormone and GH releasing hormone. Clin Endocrinol (Oxf). 1999;50(6):741–747.
   PubMed Web of Science ®Google Scholar
• Della Corte F, Mancini A, Valle D, et al. Provocative hypothalamopituitary axis tests in severe head injury: correlations with severity and prognosis. Crit Care Med. 1998;26(8):1419–1426.
   PubMed Web of Science ®Google Scholar
• Wagner J, Dusick JR, McArthur DL, et al. Acute gonadotroph and somatotroph hormonal suppression after traumatic brain injury. J Neurotrauma. 2010;27(6):1007–1019.
   PubMed Web of Science ®Google Scholar
• Bondanelli M, De Marinis L, Ambrosio MR, et al. Occurrence of pituitary dysfunction following traumatic brain injury. J Neurotrauma. 2004;21(6):685‐96.
   PubMed Web of Science ®Google Scholar
• Leal-Cerro A, Flores JM, Rincon M, et al. Prevalence of hypopituitarism and growth hormone deficiency in adults long-term after severe traumatic brain injury. Clin Endocrinol (Oxf). 2005;62(5):525‐32.
   PubMed Web of Science ®Google Scholar
• Kokshoorn NE, Smit JW, Nieuwlaat WA, et al. Low prevalence of hypopituitarism after traumatic brain injury: a multicenter study. Eur J Endocrinol. 2011;165(2):225‐31.
   PubMed Web of Science ®Google Scholar
• Frendl I, Katko M, Galgoczi E, et al. Plasminogen activator inhibitor type 1: a possible novel biomarker of late pituitary dysfunction after mild traumatic brain injury. J Neurotrauma. 2017;34(23):3238‐44.
   PubMed Web of Science ®Google Scholar
• Giuliano S, Talarico S, Bruno L, et al. Growth hormone deficiency and hypopituitarism in adults after complicated mild traumatic brain injury. Endocrine. 2017;58(1):115–123.
   PubMed Web of Science ®Google Scholar
• Kelestimur F, Tanriverdi F, Atmaca H, et al. Boxing as a sport activity associated with isolated GH deficiency. J Endocrinol Invest. 2004;27(11):RC28–RC32.
   PubMed Web of Science ®Google Scholar
• Kelly DF, Chaloner C, Evans D, et al. Prevalence of pituitary hormone dysfunction, metabolic syndrome, and impaired quality of life in retired professional football players: a prospective study. J Neurotrauma. 2014;31(13):1161–1171.
   PubMed Web of Science ®Google Scholar
• Lithgow K, Chin A, Debert CT, et al. Utility of serum IGF-1 for diagnosis of growth hormone deficiency following traumatic brain injury and sport-related concussion. BMC Endocr Disord. 2018;18(1):20.
   PubMedGoogle Scholar
• Roser P, Wehrhahn T, Krogmann H, et al. Somatotrope Pituitary Function in Professional Soccer Players. Exp Clin Endocrinol Diabetes. 2018;126(5):306–308.
   PubMed Web of Science ®Google Scholar
• Woolf PD, Lee LA, Hamill RW, et al. Thyroid test abnormalities in traumatic brain injury: correlation with neurologic impairment and sympathetic nervous system activation. Am J Med. 1988;84(2):201–208.
   PubMed Web of Science ®Google Scholar
• Malekpour B, Mehrafshan A, Saki F, et al. Effect of posttraumatic serum thyroid hormone levels on severity and mortality of patients with severe traumatic brain injury. Acta Med Iran. 2012;50(2):113–116.
   PubMedGoogle Scholar
• Chioléro R, Lemarchand T, Schutz Y, et al. Plasma pituitary hormone levels in severe trauma with or without head injury. J Trauma. 1988;28(9):1368–1374.
   PubMedGoogle Scholar
• Cernak I, Savic VJ, Lazarov A, et al. Neuroendocrine responses following graded traumatic brain injury in male adults. Brain Inj. 1999;13(12):1005–1015.
   PubMed Web of Science ®Google Scholar
• Ives JC, Alderman M, Stred SE. Hypopituitarism after multiple concussions: a retrospective case study in an adolescent male. J Athl Train. 2007;42(3):431–439.
   PubMed Web of Science ®Google Scholar
• Foley CM, Wang DH. Central diabetes insipidus following a sports-related concussion: a case report. Sports Health. 2012;4(2):139–141.
   PubMedGoogle Scholar
• Matsuura H, Nakazawa S, Wakabayashi I. Thyrotropin releasing hormone provocative release of prolactin and thyrotropin in acute head injury. Neurosurgery. 1985;16(6):791–795.
   PubMed Web of Science ®Google Scholar
• Hohl A, Ronsoni MF, Debona R, et al. Role of hormonal levels on hospital mortality for male patients with severe traumatic brain injury. Brain Inj. 2014;28(10):1262–1269.
   PubMed Web of Science ®Google Scholar
• Van den Berghe G. On the neuroendocrinopathy of critical illness. perspectives for feeding and novel treatments. Am J Respir Crit Care Med. 2016 1;194(11):1337–1348.
   PubMed Web of Science ®Google Scholar
• Snook ML, Henry LC, Sanfilippo JS, et al. Association of concussion with abnormal menstrual patterns in adolescent and young women. JAMA Pediatr. 2017;171(9):879–886.
   PubMed Web of Science ®Google Scholar
• Agha A, Thornton E, O’Kelly P, et al. Posterior pituitary dysfunction after traumatic brain injury. J Clin Endocrinol Metab. 2004;89:5987–5992.
   PubMed Web of Science ®Google Scholar
• Hadjizacharia P, Beale EO, Inaba K, et al. Acute diabetes insipidus in severe head injury: a prospective study. J Am Coll Surg. 2008;207:477–484.
   PubMed Web of Science ®Google Scholar
• Karali V, Massa E, Vassiliadou G, et al. Evaluation of development of diabetes insipidus in the early phase following traumatic brain injury in critically ill patients. Crit Care. 2008;12(Suppl 2):P130.
   PubMedGoogle Scholar
• Alaca R, Yilmaz B, Gunduz S. Anterior hypopituitarism with unusual delayed onset of diabetes insipidus after penetrating head injury. Am J Phys Med Rehabil. 2002;81(10):788‐91.
   Web of Science ®Google Scholar
• Maggiore U, Picetti E, Antonucci E, et al. The relation between the incidence of hypernatremia and mortality in patients with severe traumatic brain injury. Crit Care. 2009;13(4):R110.
   PubMed Web of Science ®Google Scholar
• Gempeler A, Orrego-González E, Hernandez-Casanas A, et al. Incidence and effect of diabetes insipidus in the acute care of patients with severe traumatic brain injury. Neurocrit Care. 2020. DOI:10.1007/s12028-020-00955-x.
   PubMed Web of Science ®Google Scholar
• Sherlock M, O’Sullivan E, Agha A, et al. Incidence and pathophysiology of severe hyponatraemia in neurosurgical patients. Postgrad Med J. 2009;85:171–175.
   PubMed Web of Science ®Google Scholar
• Northam WT, Alexander A, Carneiro K. Sport-related concussion preceding adrenal insufficiency and hypopituitarism. Curr Sports Med Rep. 2020;19(1):8–10.
   PubMed Web of Science ®Google Scholar
• Kaulfers AM, Backeljauw PF, Reifschneider K, et al. Endocrine dysfunction following traumatic brain injury in children. J Pediatr. 2010;157(6):894‐9.
   PubMed Web of Science ®Google Scholar
• Bellone S, Einaudi S, Caputo M, et al. Measurement of height velocity is an useful marker for monitoring pituitary function in patients who had traumatic brain injury. Pituitary. 2013;16(4):499‐506.
   Web of Science ®Google Scholar
• Einaudi S, Matarazzo P, Peretta P, et al. Hypothalamo-hypophysial dysfunction after traumatic brain injury in children and adolescents: a preliminary retrospective and prospective study. J Pediatr Endocrinol Metab. 2006;19(5):691‐703.
   Web of Science ®Google Scholar
• Krahulik D, Aleksijevic D, Smolka V, et al. Prospective study of hypothalamo-hypophyseal dysfunction in children and adolescents following traumatic brain injury. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017;161(1):80–85.
   PubMed Web of Science ®Google Scholar
• Khadr SN, Crofton PM, Jones PA, et al. Evaluation of pituitary function after traumatic brain injury in childhood. Clin Endocrinol (Oxf). 2010;73(5):637‐43.
   PubMed Web of Science ®Google Scholar
• Niederland T, Makovi H, Gál V, et al. Abnormalities of pituitary function after traumatic brain injury in children. J Neurotrauma. 2007;24(1):119‐27.
   PubMed Web of Science ®Google Scholar
• Auble BA, Bollepalli S, Makoroff K, et al. Hypopituitarism in pediatric survivors of inflicted traumatic brain injury. J Neurotrauma. 2014;31(4):321‐6.
   PubMed Web of Science ®Google Scholar
• Aimaretti G, Ambrosio MR, Di Somma C, et al. Hypopituitarism induced by traumatic brain injury in the transition phase. J Endocrinol Invest. 2005;28(11):984‐9.
   Web of Science ®Google Scholar
• Briet C, Braun K, Lefranc M, et al. Should we assess pituitary function in children after a mild traumatic brain injury? A prospective study. Front Endocrinol (Lausanne). 2019;10:149.
   PubMed Web of Science ®Google Scholar
• Salomón-Estébanez MA, Grau G, Vela A, et al. Is routine endocrine evaluation necessary after paediatric traumatic brain injury?J. Endocrinol Invest. 2014;37(2):143‐8.
   PubMed Web of Science ®Google Scholar
• Moon RJ, Sutton T, Wilson PM, et al. Pituitary function at long-term follow-up of childhood traumatic brain injury. J Neurotrauma. 2010;27(10):1827‐35.
   Web of Science ®Google Scholar
• Ortiz JB, Sukhina A, Balkan B, et al. Epidemiology of pediatric traumatic brain injury and hypothalamic-pituitary disorders in arizona. Front Neurol. 2020;10:1410.
   PubMed Web of Science ®Google Scholar
• Heather NL, Jefferies C, Hofman PL, et al. Permanent hypopituitarism is rare after structural traumatic brain injury in early childhood. J Clin Endocrinol Metab. 2012;97(2):599‐604.
   PubMed Web of Science ®Google Scholar
• Norwood KW, Deboer MD, Gurka MJ, et al. Traumatic brain injury in children and adolescents: surveillance for pituitary dysfunction. Clin Pediatr (Phila). 2010;49(11):1044‐9.
   PubMed Web of Science ®Google Scholar
• Srinivas R, Brown SD, Chang YF, et al. Endocrine function in children acutely following severe traumatic brain injury. Childs Nerv Syst. 2010;26(5):647‐53.
   PubMed Web of Science ®Google Scholar
• Ulutabanca H, Hatipoglu N, Tanriverdi F, et al. Prospective investigation of anterior pituitary function in the acute phase and 12 months after pediatric traumatic brain injury. Childs Nerv Syst. 2014;30(6):1021–1028.
   PubMed Web of Science ®Google Scholar
• Casano-Sancho P, Suárez L, Ibáñez L, et al. Pituitary dysfunction after traumatic brain injury in children: is there a need for ongoing endocrine assessment? Clin Endocrinol (Oxf). 2013;79(6):853‐8.
   PubMed Web of Science ®Google Scholar
• Personnier C, Crosnier H, Meyer P, et al. Prevalence of pituitary dysfunction after severe traumatic brain injury in children and adolescents: a large prospective study. J Clin Endocrinol Metab. 2014;99(6):2052‐60.
   PubMed Web of Science ®Google Scholar
• Grimberg A, DiVall SA, Polychronakos C, et al. Drug and therapeutics committee and ethics committee of the pediatric endocrine society. guidelines for growth hormone and insulin-like growth factor-i treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin-like growth factor-I deficiency. Horm Res Paediatr. 2016;86(6):361–397.
   PubMed Web of Science ®Google Scholar
• Collett-Solberg PF, Ambler G, Backeljauw PF, et al. Diagnosis, genetics, and therapy of short stature in children: a growth hormone research society international perspective. Horm Res Paediatr. 2019;92(1):1‐14.
   PubMed Web of Science ®Google Scholar
• Daskas N, Sharples P, Likeman M, et al. Growth hormone secretion, fatigue and quality of life after childhood traumatic brain injury. Eur J Endocrinol. 2019;181(3):331‐8.
   PubMed Web of Science ®Google Scholar
• Poomthavorn P, Maixner W, Zacharin M. Pituitary function in paediatric survivors of severe traumatic brain injury. Arch Dis Child. 2008;93(2):133‐7.
   PubMed Web of Science ®Google Scholar
• De Sanctis V, Soliman AT, Elsedfy H, et al. Precocious puberty following traumatic brain injury in early childhood: a review of the literature. Pediatr Endocrinol Rev. 2015;13(1):458‐64.
   Web of Science ®Google Scholar
• Dassa Y, Crosnier H, Chevignard M, et al. Pituitary deficiency and precocious puberty after childhood severe traumatic brain injury: a long-term follow-up prospective study. Eur J Endocrinol. 2019;180(5):281–290.
   PubMed Web of Science ®Google Scholar
• Hoffman H, Jalal MS, Chin LS. Effect of hypernatremia on outcomes after severe traumatic brain injury: a nationwide inpatient sample analysis. World Neurosurg. 2018;118:e880‐e886.
   PubMed Web of Science ®Google Scholar
• Fleseriu M, Hashim IA, Karavitaki N, et al. Hormonal replacement in hypopituitarism in adults: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2016;101(11):3888‐3921.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, Schneider HJ, Aimaretti G, et al. Pituitary dysfunction after traumatic brain injury: a clinical and pathophysiological approach. Endocr Rev. 2015;36(3):305‐42.
   PubMed Web of Science ®Google Scholar
• Tritos NA, Yuen KC, Kelly DF. AACE neuroendocrine and pituitary scientific committee. American association of clinical endocrinologists and American college of endocrinology disease state clinical review: a neuroendocrine approach to patients with traumatic brain injury. Endocr Pract. 2015;21(7):823‐31.
   PubMed Web of Science ®Google Scholar
• Tan CL, Alavi SA, Baldeweg SE, et al. The screening and management of pituitary dysfunction following traumatic brain injury in adults: british Neurotrauma Group guidance. J Neurol Neurosurg Psychiatry. 2017;88(11):971‐81.
   Web of Science ®Google Scholar
• Hacioglu A, Kelestimur F, Tanriverdi F. Long-term neuroendocrine consequences of traumatic brain injury and strategies for management. Expert Rev Endocrinol Metab. 2020;15(2):123–139.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, De Bellis A, Bizzarro A, et al. Antipituitary antibodies after traumatic brain injury: is head trauma-induced pituitary dysfunction associated with autoimmunity? Eur J Endocrinol. 2008;159(1):7–13.
   PubMed Web of Science ®Google Scholar
• Tanriverdi F, De Bellis A, Battaglia M, et al. Investigation of antihypothalamus and antipituitary antibodies in amateur boxers: is chronic repetitive head trauma-induced pituitary dysfunction associated with autoimmunity? Eur J Endocrinol. 2010;162(5):861–867.
   PubMed Web of Science ®Google Scholar
• Wright T, Urban R, Durham W, et al. Growth hormone alters brain morphometry, connectivity, and behavior in subjects with fatigue after mild traumatic brain injury. J Neurotrauma. 2020;37(8):1052‐66.
   Web of Science ®Google Scholar