The links between allergen exposure and sensitization in children and adolescents: an overview for the clinician

References

• Asher MI, Rutter CE, Bissell K, et al. Worldwide trends in the burden of asthma symptoms in school-aged children: global Asthma network phase I cross-sectional study. Lancet. 2021 Oct 30;398(10311):1569–1580. PubMed PMID: 34755626; eng.
   PubMed Web of Science ®Google Scholar
• Moustaki M, Fretzayas A. How much asthma is due to atopy?. Allergol Int. 2010 Jun;59(2):229. PubMed PMID: 20179420; eng.
   PubMedGoogle Scholar
• Custovic A. To what extent is allergen exposure a risk factor for the development of allergic disease?. Clin Exp Allergy. 2015 Jan;45(1):54–62. PubMed PMID: 25381695; eng.
   PubMed Web of Science ®Google Scholar
• Custovic A, Woodcock A. Exposure and sensitization in infants and children. Curr Opin Allergy Clin Immunol. 2001 Apr;1(2):133–138. PubMed PMID: 11964680; eng.
   PubMedGoogle Scholar
• Sampson HA, O’Mahony L, Burks AW, et al. Mechanisms of food allergy. J Allergy Clin Immunol. 2018 Jan;141(1):11–19. PubMed PMID: 29307410; eng.
   PubMed Web of Science ®Google Scholar
• Boyce JA, Assa’ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. Nutr Res. 2011 Jan;31(1):61–75. PubMed PMID: 21310308; PubMed Central PMCID: PMCPMC4249938. eng.
   PubMed Web of Science ®Google Scholar
• Nowak-Węgrzyn A, Chatchatee P. Mechanisms of tolerance induction. Ann Nutr Metab. 2017;70(2):7–24. PubMed PMID: 28521317; eng.
   PubMedGoogle Scholar
• Loibichler C, Pichler J, Gerstmayr M, et al. Materno-fetal passage of nutritive and inhalant allergens across placentas of term and pre-term deliveries perfused in vitro. Clin Exp Allergy. 2002 Nov;32(11):1546–1551. PubMed PMID: 12569973; eng.
   PubMedGoogle Scholar
• Kramer MS, Kakuma R. Cochrane in context: maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Evid Based Child Health. 2014 Jun;9(2):484–485. PubMed PMID: 25404610; eng.
   PubMedGoogle Scholar
• Netting MJ, Middleton PF, Makrides M. Does maternal diet during pregnancy and lactation affect outcomes in offspring? A systematic review of food-based approaches. Nutrition. 2014 Nov-Dec;30(11–12):1225–1241. PubMed PMID: 25280403; eng.
   PubMed Web of Science ®Google Scholar
• Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database Syst Rev. 2012 Sep 12;2012(9):Cd000133. PubMed PMID: 22972039; PubMed Central PMCID: PMCPMC7045459. eng.
   Google Scholar
• de Silva D, Geromi M, Halken S, et al. Primary prevention of food allergy in children and adults: systematic review. Allergy. 2014 May;69(5):581–589. PubMed PMID: 24433563; eng.
   PubMed Web of Science ®Google Scholar
• Greer FR, Sicherer SH, Burks AW. The effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, hydrolyzed formulas, and timing of introduction of allergenic complementary foods. Pediatrics. 2019 Apr;143(4). doi:https://doi.org/10.1542/peds.2019-0281. PubMed PMID: 30886111; eng.
   PubMed Web of Science ®Google Scholar
• Greer FR, Sicherer SH, Burks AW. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics. 2008 Jan;121(1):183–191. PubMed PMID: 18166574; eng.
   PubMed Web of Science ®Google Scholar
• Prescott SL, Smith P, Tang M, et al. The importance of early complementary feeding in the development of oral tolerance: concerns and controversies. Pediatr Allergy Immunol. 2008 Aug;19(5):375–380. PubMed PMID: 18266825; eng.
   PubMed Web of Science ®Google Scholar
• American Academy of Pediatrics. Committee on Nutrition. Hypoallergenic infant formulas. Pediatrics. 2000 Aug; 106(2):346–349. PubMed PMID: 10920165; eng.
   PubMed Web of Science ®Google Scholar
• Fiocchi A, Assa’ad A, Bahna S. Food allergy and the introduction of solid foods to infants: a consensus document. adverse reactions to foods committee, American college of allergy, asthma and immunology. Ann Allergy Asthma Immunol. 2006 Jul;97(1):10–20.
   PubMed Web of Science ®Google Scholar
• Poulos LM, Waters AM, Correll PK, et al. Trends in hospitalizations for anaphylaxis, angioedema, and urticaria in Australia, 1993-1994 to 2004-2005. J Allergy Clin Immunol. 2007 Oct;120(4):878–884. PubMed PMID: 17931562; eng.
   PubMed Web of Science ®Google Scholar
• Koplin JJ, Osborne NJ, Wake M, et al. Can early introduction of egg prevent egg allergy in infants? A population-based study. J Allergy Clin Immunol. 2010 Oct;126(4):807–813. PubMed PMID: 20920771; eng.
   PubMed Web of Science ®Google Scholar
• Poole JA, Barriga K, Leung DY, et al. Timing of initial exposure to cereal grains and the risk of wheat allergy. Pediatrics. 2006 Jun;117(6):2175–2182. PubMed PMID: 16740862; eng.
   PubMed Web of Science ®Google Scholar
• Sausenthaler S, Heinrich J, Koletzko S. Early diet and the risk of allergy: what can we learn from the prospective birth cohort studies GINIplus and LISAplus?. Am J Clin Nutr. 2011 Dec;94(suppl_6):2012s–2017s. PubMed PMID: 21543544; eng.
   PubMedGoogle Scholar
• Peters RL, Koplin JJ, Dharmage SC, et al. Early exposure to cow’s milk protein is associated with a reduced risk of cow’s milk allergic outcomes. The Journal of Allergy and Clinical Immunology in Practice. 2019 Feb;7(2):462–470.e1. PubMed PMID: 30267891; eng.
   PubMedGoogle Scholar
• Onizawa Y, Noguchi E, Okada M, et al. The association of the delayed introduction of cow’s milk with ige-mediated cow’s milk allergies. The Journal of Allergy and Clinical Immunology in Practice. 2016 May-Jun;4(3):481–488.e2. PubMed PMID: 27157937; eng.
   PubMed Web of Science ®Google Scholar
• Sakihara T, Otsuji K, Arakaki Y, et al. Randomized trial of early infant formula introduction to prevent cow’s milk allergy. J Allergy Clin Immunol. 2021 Jan;147(1):224–232.e8. PubMed PMID: 32890574; eng.
   PubMedGoogle Scholar
• Ierodiakonou D, Garcia-Larsen V, Logan A, et al. timing of allergenic food introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis. jama. 2016 Sep 20;316(11):1181–1192. PubMed PMID: 27654604; eng.
   PubMed Web of Science ®Google Scholar
• Du Toit G, Roberts G, Sayre PH, et al. Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015 Feb 26;372(9):803–813. PubMed PMID: 25705822; PubMed Central PMCID: PMCPMC4416404. eng.
   PubMed Web of Science ®Google Scholar
• Fleischer DM, Sicherer S, Greenhawt M, et al. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. J Allergy Clin Immunol. 2015 Aug;136(2):258–261. PubMed PMID: 26100082; eng.
   PubMedGoogle Scholar
• Perkin MR, Logan K, Tseng A, et al. Randomized trial of introduction of allergenic foods in breast-fed infants. N Engl J Med. 2016 May 5;374(18):1733–1743. PubMed PMID: 26943128; eng.
   PubMed Web of Science ®Google Scholar
• Halken S, Muraro A, de Silva D, et al. EAACI guideline: preventing the development of food allergy in infants and young children (2020 update). Pediatr Allergy Immunol. 2021 Jul;32(5):843–858. PubMed PMID: 33710678; eng.
   PubMedGoogle Scholar
• Lack G. Update on risk factors for food allergy. J Allergy Clin Immunol. 2012 May;129(5):1187–1197. PubMed PMID: 22464642; eng.
   PubMed Web of Science ®Google Scholar
• Fox DE, Lack GPA. Peanut allergy. Lancet. 1998 Aug 29;352(9129):741. PubMed PMID: 9729023; eng.
   PubMedGoogle Scholar
• Strid J, Hourihane J, Kimber I, et al. Epicutaneous exposure to peanut protein prevents oral tolerance and enhances allergic sensitization. Clin Exp Allergy. 2005 Jun;35(6):757–766. PubMed PMID: 15969667; eng.
   PubMed Web of Science ®Google Scholar
• Strid J, Hourihane J, Kimber I, et al. Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response. Eur J Immunol. 2004 Aug;34(8):2100–2109. PubMed PMID: 15259007; eng.
   PubMedGoogle Scholar
• Fox AT, Sasieni P, du Toit G, et al. Household peanut consumption as a risk factor for the development of peanut allergy. J Allergy Clin Immunol. 2009 Feb;123(2):417–423. PubMed PMID: 19203660; eng.
   PubMed Web of Science ®Google Scholar
• Brough HA, Liu AH, Sicherer S, et al. Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy. J Allergy Clin Immunol. 2015 Jan;135(1):164–170. PubMed PMID: 25457149; PubMed Central PMCID: PMCPMC4282723. eng.
   PubMed Web of Science ®Google Scholar
• Shroba J, Barnes C, Nanda M, et al. Ara h2 levels in dust from homes of individuals with peanut allergy and individuals with peanut tolerance. Allergy Asthma Proc. 2017 May 1;38(3):192–196. PubMed PMID: 28441989; PubMed Central PMCID: PMCPMC6479458. eng.
   PubMedGoogle Scholar
• Lack G, Fox D, Northstone K, et al. Factors associated with the development of peanut allergy in childhood. N Engl J Med. 2003 Mar 13;348(11):977–985. PubMed PMID: 12637607; eng.
   PubMed Web of Science ®Google Scholar
• Gray LEK, Ponsonby AL, Collier F, et al. Deserters on the atopic march: risk factors, immune profile and clinical outcomes of food sensitized-tolerant infants. Allergy. 2020 Jun;75(6):1404–1413. PubMed PMID: 31853983; eng.
   PubMedGoogle Scholar
• Gupta RS, Walkner MM, Greenhawt M, et al. Food allergy sensitization and presentation in siblings of food allergic children. The Journal of Allergy and Clinical Immunology in Practice. 2016 Sep-Oct;4(5):956–962. PubMed PMID: 27421900; PubMed Central PMCID: PMCPMC5010481. eng.
   PubMedGoogle Scholar
• Voorhorst R, Spieksma FT. Correspondence: of mites and men. J Allergy. 1967 Dec;40(6):357–358. PubMed PMID: 5235624; eng.
   PubMedGoogle Scholar
• Tovey ER, Marks GB. It’s time to rethink mite allergen avoidance. J Allergy Clin Immunol. 2011 Oct;128(4):723–727.e6. PubMed PMID: 21855978; eng.
   PubMed Web of Science ®Google Scholar
• Jones CA, Kilburn SA, Warner JA, et al. Intrauterine environment and fetal allergic sensitization. Clin Exp Allergy. 1998 Jun;28(6):655–659. PubMed PMID: 9677126; eng.
   PubMedGoogle Scholar
• Hagendorens MM, Ebo DG, Bridts CH, et al. Prenatal exposure to house dust mite allergen (Der p 1), cord blood T cell phenotype and cytokine production and atopic dermatitis during the first year of life. Pediatr Allergy Immunol. 2004 Aug;15(4):308–315. PubMed PMID: 15305939; eng.
   PubMedGoogle Scholar
• Rowe J, Kusel M, Holt BJ, et al. Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort. J Allergy Clin Immunol. 2007 May;119(5):1164–1173. PubMed PMID: 17412403; eng.
   PubMedGoogle Scholar
• Lau S, Falkenhorst G, Weber A, et al. High mite-allergen exposure increases the risk of sensitization in atopic children and young adults. J Allergy Clin Immunol. 1989 Nov;84(5):718–725. PubMed PMID: 2478606; eng.
   PubMedGoogle Scholar
• Sporik R, Holgate ST, Platts-Mills TA, et al. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med. 1990 Aug 23;323(8):502–507. PubMed PMID: 2377175; eng.
   PubMed Web of Science ®Google Scholar
• Wahn U, Lau S, Bergmann R, et al. Indoor allergen exposure is a risk factor for sensitization during the first three years of life. J Allergy Clin Immunol. 1997 Jun;99(8):763–769. PubMed PMID: 9215243; eng.
   PubMedGoogle Scholar
• Brussee JE, Smit HA, van Strien RT, et al. Allergen exposure in infancy and the development of sensitization, wheeze, and asthma at 4 years. J Allergy Clin Immunol. 2005 May;115(5):946–952. PubMed PMID: 15867850; eng.
   PubMedGoogle Scholar
• Cullinan P, MacNeill SJ, Harris JM, et al. Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study. Thorax. 2004 Oct;59(10):855–861. PubMed PMID: 15454651; PubMed Central PMCID: PMCPMC1746847. eng.
   PubMedGoogle Scholar
• Schram-Bijkerk D, Doekes G, Boeve M, et al. Nonlinear relations between house dust mite allergen levels and mite sensitization in farm and nonfarm children. Allergy. 2006 May;61(5):640–647. PubMed PMID: 16629797; eng.
   PubMed Web of Science ®Google Scholar
• Tovey ER, Almqvist C, Li Q, et al. Nonlinear relationship of mite allergen exposure to mite sensitization and asthma in a birth cohort. J Allergy Clin Immunol. 2008 Jul;122(1):114–115. PubMed PMID: 18602569; eng.
   PubMedGoogle Scholar
• Torrent M, Sunyer J, Muñoz L, et al. Early-life domestic aeroallergen exposure and IgE sensitization at age 4 years. J Allergy Clin Immunol. 2006 Sep;118(3):742–748. PubMed PMID: 16950296; eng.
   PubMedGoogle Scholar
• Casas L, Sunyer J, Tischer C, et al. Early-life house dust mite allergens, childhood mite sensitization, and respiratory outcomes. Allergy. 2015 Jul;70(7):820–827. PubMed PMID: 25858551; eng. .
   PubMedGoogle Scholar
• Chan-Yeung M, Ferguson A, Watson W, et al. The Canadian childhood asthma primary prevention study: outcomes at 7 years of age. J Allergy Clin Immunol. 2005 Jul;116(1):49–55. PubMed PMID: 15990772; eng.
   PubMed Web of Science ®Google Scholar
• Becker A, Watson W, Ferguson A, et al. The Canadian asthma primary prevention study: outcomes at 2 years of age. J Allergy Clin Immunol. 2004 Apr;113(4):650–656. PubMed PMID: 15100668; eng.
   PubMedGoogle Scholar
• Peat JK, Mihrshahi S, Kemp AS, et al. Three-year outcomes of dietary fatty acid modification and house dust mite reduction in the childhood asthma prevention study. J Allergy Clin Immunol. 2004 Oct;114(4):807–813. PubMed PMID: 15480319; eng.
   PubMedGoogle Scholar
• Arshad SH, Bateman B, Matthews SM. Primary prevention of asthma and atopy during childhood by allergen avoidance in infancy: a randomised controlled study. Thorax. 2003 Jun;58(6):489–493. PubMed PMID: 12775858; PubMed Central PMCID: PMCPMC1746711. eng.
   PubMed Web of Science ®Google Scholar
• Woodcock A, Lowe LA, Murray CS, et al. Early life environmental control: effect on symptoms, sensitization, and lung function at age 3 years. Am J Respir Crit Care Med. 2004 Aug 15;170(4):433–439. PubMed PMID: 15142868; eng.
   PubMedGoogle Scholar
• Custovic A, Simpson A. Environmental allergen exposure, sensitisation and asthma: from whole populations to individuals at risk. Thorax. 2004 Oct;59(10):825–827. PubMed PMID: 15454646; PubMed Central PMCID: PMCPMC1746833. eng.
   PubMedGoogle Scholar
• Chen CM, Tischer C, Schnappinger M, et al. The role of cats and dogs in asthma and allergy–a systematic review. Int J Hyg Environ Health. 2010 Jan;213(1):1–31. PubMed PMID: 20053584; eng.
   PubMedGoogle Scholar
• Al-Mousawi MS, Lovel H, Behbehani N, et al. Asthma and sensitization in a community with low indoor allergen levels and low pet-keeping frequency. J Allergy Clin Immunol. 2004 Dec;114(6):1389–1394. PubMed PMID: 15577842; eng.
   PubMedGoogle Scholar
• Lødrup Carlsen KC, Roll S, Carlsen KH, et al. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS One. 2012;7(8):e43214. PubMed PMID: 22952649; PubMed Central PMCID: PMCPMC3430634. eng.
   PubMed Web of Science ®Google Scholar
• Melén E, Wickman M, Nordvall SL, et al. Influence of early and current environmental exposure factors on sensitization and outcome of asthma in pre-school children. Allergy. 2001 Jul;56(7):646–652. PubMed PMID: 11421923; eng.
   PubMedGoogle Scholar
• Custovic A, Simpson BM, Simpson A, et al. Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet. 2001 Jul 21;358(9277):188–193. PubMed PMID: 11476835; eng.
   PubMed Web of Science ®Google Scholar
• Perzanowski MS, Chew GL, Divjan A, et al. Cat ownership is a risk factor for the development of anti-cat IgE but not current wheeze at age 5 years in an inner-city cohort. J Allergy Clin Immunol. 2008 Apr;121(4):1047–1052. PubMed PMID: 18395554; PubMed Central PMCID: PMCPMC3131176. eng.
   PubMedGoogle Scholar
• Lodge CJ, Lowe AJ, Gurrin LC, et al. Pets at birth do not increase allergic disease in at-risk children. Clin Exp Allergy. 2012 Sep;42(9):1377–1385. PubMed PMID: 22925324; eng.
   PubMedGoogle Scholar
• Mandhane PJ, Sears MR, Poulton R, et al. Cats and dogs and the risk of atopy in childhood and adulthood. J Allergy Clin Immunol. 2009 Oct;124(4):745–50.e4. PubMed PMID: 19703709; eng.
   PubMedGoogle Scholar
• Hesselmar B, Aberg N, Aberg B, et al. Does early exposure to cat or dog protect against later allergy development?. Clin Exp Allergy. 1999 May;29(5):611–617. PubMed PMID: 10231320; eng.
   PubMed Web of Science ®Google Scholar
• Wegienka G, Johnson CC, Havstad S, et al. Lifetime dog and cat exposure and dog- and cat-specific sensitization at age 18 years. Clin Exp Allergy. 2011 Jul;41(7):979–986. PubMed PMID: 21668818; PubMed Central PMCID: PMCPMC3737566. eng.
   PubMedGoogle Scholar
• Roost HP, Künzli N, Schindler C, et al. Role of current and childhood exposure to cat and atopic sensitization European community respiratory health survey. J Allergy Clin Immunol. 1999 Nov;104(5):941–947. PubMed PMID: 10550736; eng.
   PubMed Web of Science ®Google Scholar
• Ritz BR, Hoelscher B, Frye C, et al. Allergic sensitization owing to ‘second-hand’ cat exposure in schools. Allergy. 2002 Apr;57(4):357–361. PubMed PMID: 11906369; eng.
   PubMedGoogle Scholar
• Chen CM, Rzehak P, Zutavern A, et al. Longitudinal study on cat allergen exposure and the development of allergy in young children. J Allergy Clin Immunol. 2007 May;119(5):1148–1155. PubMed PMID: 17399781; eng.
   PubMedGoogle Scholar
• Ihuoma H, Belgrave DC, Murray CS, et al. Cat ownership, cat allergen exposure, and trajectories of sensitization and asthma throughout childhood. J Allergy Clin Immunol. 2018 Feb;141(2):820–822.e7. PubMed PMID: 29111216; PubMed Central PMCID: PMCPMC5792051. Eng.
   PubMed Web of Science ®Google Scholar
• Hesselmar B, Aberg B, Eriksson B, et al. High-dose exposure to cat is associated with clinical tolerance–a modified Th2 immune response?. Clin Exp Allergy. 2003 Dec;33(12):1681–1685. PubMed PMID: 14656355; eng.
   PubMedGoogle Scholar
• Canfield SM, Jacobson JS, Perzanowski MS, et al. Total and specific IgE associations between New York City head start children and their parents. J Allergy Clin Immunol. 2008 Jun;121(6):1422–1427. PubMed PMID: 18472147; eng.
   PubMedGoogle Scholar
• Hopp RJ, Bewtra AK, Watt GD, et al. Genetic analysis of allergic disease in twins. J Allergy Clin Immunol. 1984 Feb;73(2):265–270. PubMed PMID: 6538209; eng.
   PubMedGoogle Scholar
• Strachan DP, Wong HJ, Spector TD. Concordance and interrelationship of atopic diseases and markers of allergic sensitization among adult female twins. J Allergy Clin Immunol. 2001 Dec;108(6):901–907. PubMed PMID: 11742265; eng.
   PubMed Web of Science ®Google Scholar
• Hanson B, McGue M, Roitman-Johnson B, et al. Atopic disease and immunoglobulin E in twins reared apart and together. Am J Hum Genet. 1991 May;48(5):873–879. PubMed PMID: 2018039; PubMed Central PMCID: PMCPMC1683042. Eng.
   PubMedGoogle Scholar
• Misiak RT, Wegienka G, Zoratti E. Are specific allergen sensitivities inherited?. Curr Allergy Asthma Rep. 2010 Sep;10(5):336–339. PubMed PMID: 20574668; eng.
   PubMed Web of Science ®Google Scholar
• Simpson A, Brough HA, Haider S, et al. Early-life inhalant allergen exposure, filaggrin genotype, and the development of sensitization from infancy to adolescence. J Allergy Clin Immunol. 2020 Mar;145(3):993–1001. PubMed PMID: 31629803; PubMed Central PMCID: PMCPMC7057264. Eng.
   PubMedGoogle Scholar
• Brough HA, Simpson A, Makinson K, et al. Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations. J Allergy Clin Immunol. 2014 Oct;134(4):867–875.e1. PubMed PMID: 25282568; PubMed Central PMCID: PMCPMC4188983. eng.
   PubMed Web of Science ®Google Scholar
• Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989 Nov 18;299(6710):1259–1260. PubMed PMID: 2513902; PubMed Central PMCID: PMCPMC1838109. eng.
   PubMed Web of Science ®Google Scholar
• Vercelli D. Microbiota and human allergic diseases: the company we keep. Curr Opin Immunol. 2021 Oct;72:215–220. PubMed PMID: 34182271; PubMed Central PMCID: PMCPMC8578191. eng.
   PubMedGoogle Scholar
• Campbell BE, Lodge CJ, Lowe AJ, et al. Exposure to ‘farming’ and objective markers of atopy: a systematic review and meta-analysis. Clin Exp Allergy. 2015 Apr;45(4):744–757. PubMed PMID: 25270644; eng.
   PubMedGoogle Scholar
• Melén E, Standl M, Gehring U, et al. Air pollution and IgE sensitization in 4 European birth cohorts-the MeDALL project. J Allergy Clin Immunol. 2021 Feb;147(2):713–722. PubMed PMID: 32926877; eng.
   PubMedGoogle Scholar
• Bowatte G, Lodge C, Lowe AJ, et al. The influence of childhood traffic-related air pollution exposure on asthma, allergy and sensitization: a systematic review and a meta-analysis of birth cohort studies. Allergy. 2015 Mar;70(3):245–256. PubMed PMID: 25495759; eng.
   PubMed Web of Science ®Google Scholar
• Strachan DP, Cook DG. Health effects of passive smoking. 5. Parental smoking and allergic sensitisation in children. Thorax. 1998 Feb;53(2):117–123. PubMed PMID: 9624297; PubMed Central PMCID: PMCPMC1758719. eng.
   PubMedGoogle Scholar
• Raherison C, Pénard-Morand C, Moreau D, et al. Smoking exposure and allergic sensitization in children according to maternal allergies. Ann Allergy Asthma Immunol. 2008 Apr;100(4):351–357. PubMed PMID: 18450121; eng.
   PubMedGoogle Scholar
• Thacher JD, Gruzieva O, Pershagen G, et al. Parental smoking and development of allergic sensitization from birth to adolescence. Allergy. 2016 Feb;71(2):239–248. PubMed PMID: 26475651; PubMed Central PMCID: PMCPMC5063181. eng.
   PubMed Web of Science ®Google Scholar
• Yao TC, Chang SW, Hua MC, et al. Tobacco smoke exposure and multiplexed immunoglobulin E sensitization in children: a population-based study. Allergy. 2016 Jan;71(1):90–98. PubMed PMID: 26416225; eng.
   PubMedGoogle Scholar