Pathways of atopic disease and neurodevelopmental impairment: assessing the evidence for infant antibiotics

References

• Rewane A, and Munakomi S. Embryology, Central Nervous System, Malformations (StatPearls Publishing), 2022.
   Google Scholar
• Subramanian L, Calcagnotto ME, and Paredes MF. Cortical malformations: lessons in human brain development. Front Cell Neurosci. 2020;13:576.
   PubMed Web of Science ®Google Scholar
• White T, Su S, and Schmidt M, et al. The development of gyrification in childhood and adolescence. Brain Cogn. 2010;72(1):36–45.
   PubMed Web of Science ®Google Scholar
• Miyanishi K, Sato A, and Kihara N, et al. Synaptic elimination by microglia and disturbed higher brain functions. Neurochem Int. 2021;142:104901.
   PubMed Web of Science ®Google Scholar
• Koyama R, and Ikegaya Y. Microglia in the pathogenesis of autism spectrum disorders. Neurosci Res. 2015;100:1–5.
   PubMed Web of Science ®Google Scholar
• Guarner F, Malagelada J-R. Gut flora in health and disease. Lancet. 2003;361(9356):512–519.
   PubMed Web of Science ®Google Scholar
• Selkrig J, Wong P, Zhang X, et al. Metabolic tinkering by the gut microbiome. Gut Microbes. 2014;5(3):369–380.
   PubMed Web of Science ®Google Scholar
• Vu K, Lou W, and Tun HM, et al. From birth to overweight and atopic disease: Multiple and common pathways of the infant gut microbiome. Gastroenterology. 2021;160(1):128–144.
   PubMed Web of Science ®Google Scholar
• Azad M, Konya T, and Persaud R, et al. Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study. Bjog. 2016;123(6):983–993.
   PubMed Web of Science ®Google Scholar
• Azad MB, Konya T, Maughan H, et al. Gut microbiota of healthy Canadian infants: Profiles by mode of delivery and infant diet at 4 months. Can Med Assoc J. 2013;185(5):385–394.
   PubMed Web of Science ®Google Scholar
• Genuneit J, Seibold AM, and Apfelbacher CJ, et al. Overview of systematic reviews in allergy epidemiology. Allergy. 2017;72(6):849–856.
   PubMed Web of Science ®Google Scholar
• Chernikova DA, Madan JC, and Housman ML, et al. The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth. Pediatr Res. 2018;84(1): 71–79.
   PubMed Web of Science ®Google Scholar
• Cong X, Xu W, and Janton S, et al. Gut microbiome developmental patterns in early life of preterm infants: Impacts of feeding and gender. PloS one. 2016;11(4): e0152751.
   PubMed Web of Science ®Google Scholar
• Matenchuk BA, Mandhane PJ, and Kozyrskyj AL. Sleep, circadian rhythm, and gut microbiota. Sleep Med Rev. 2020;53:101340.
   PubMed Web of Science ®Google Scholar
• Kozyrskyj AL, Kendall GE, Zubrick SR, et al. Frequent nocturnal awakening in early life is associated with nonatopic asthma in children. Eur Respir J. 2009;34(6):1288–1295.
   PubMed Web of Science ®Google Scholar
• Kurilshikov A, Wijmenga C, and Fu J, et al. Host genetics and gut microbiome: Challenges and perspectives. Trends Immunol. 2017;38(9) :633–647.
   PubMed Web of Science ®Google Scholar
• Jašarević E, Rodgers AB, and Bale TL. A novel role for maternal stress and microbial transmission in early life programming and neurodevelopment. Neurobiol Stress. 2015;1:81–88.
   PubMedGoogle Scholar
• Zijlmans MAC, Korpela K, and Riksen-Walraven JM, et al. Maternal prenatal stress is associated with the infant intestinal microbiota. Psychoneuroendocrinology. 2015;53:233–245.
   PubMed Web of Science ®Google Scholar
• Ho NT, Li F, and Lee-Sarwar KA, et al. Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations. Nat Commun. 2018;9(1):4169.
   PubMed Web of Science ®Google Scholar
• Tanaka S, Kobayashi T, and Songjinda P, et al. Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota. FEMS Immunol Med Microbiol. 2009;56(1): ;80–7.
   PubMedGoogle Scholar
• Cryan JF, O’Riordan KJ, and Cowan CSM, et al. The microbiota-gut-brain axis. Physiol Rev. 2019;99(4): 1877–2013.
   PubMed Web of Science ®Google Scholar
• Tun HM, Konya T, and Takaro TK, et al. Exposure to household furry pets influences the gut microbiota of infants at 3–4 months following various birth scenarios. Microbiome. 2017;5(1):40. .
   PubMedGoogle Scholar
• Azad MB, Konya T, and Maughan H, et al. Infant gut microbiota and the hygiene hypothesis of allergic disease: impact of household pets and siblings on microbiota composition and diversity. Allergy Asthma Clin Immunol. 2013;9(1):15.
   PubMed Web of Science ®Google Scholar
• Nielsen CC, Gascon M, and Osornio-Vargas AR, et al. Natural environments in the urban context and gut microbiota in infants. Environ Int. 2020;142:105881.
   PubMed Web of Science ®Google Scholar
• Iannone LF, Preda A, Blottière HM, et al. Microbiota-gut brain axis involvement in neuropsychiatric disorders. Expert Rev Neurother. 2019;19(10):1037–1050.
   PubMed Web of Science ®Google Scholar
• Silva YP, Bernardi A, and Frozza RL. The role of short-chain fatty acids from gut microbiota in gut-brain communication. Front Endocrinol (Lausanne). 2020;11:25.
   PubMed Web of Science ®Google Scholar
• Agus A, Planchais J, and Sokol H. Gut microbiota regulation of tryptophan metabolism in health and disease. Cell Host Microbe. 2018;23(6): 716–724.
   PubMed Web of Science ®Google Scholar
• MahmoudianDehkordi S, Arnold M, and Nho K, et al. Altered bile acid profile associates with cognitive impairment in alzheimer’s disease-an emerging role for gut microbiome. Alzheimers Dement. 2019;15(1):76–92.
   PubMed Web of Science ®Google Scholar
• Bauer KC, Rees T, and Finlay BB. the gut microbiota–brain axis expands neurologic function: A nervous rapport. BioEssays. 2019;41(10):e1800268.
   PubMed Web of Science ®Google Scholar
• Cerdó T, Diéguez E, and Campoy C. Impact of gut microbiota on neurogenesis and neurological diseases during infancy. Curr Opin Pharmacol. 2020;50:33–37.
   PubMed Web of Science ®Google Scholar
• Cowan CSM, Dinan TG, and Cryan JF. Annual research review: Critical windows – the microbiota–gut–brain axis in neurocognitive development. J Child Psychol Psychiatry. 2020;61(3) :353–371. .
   PubMed Web of Science ®Google Scholar
• Lebovitz Y, Ringel-Scaia VM, and Allen IC, et al. emerging developments in microbiome and microglia research: Implications for neurodevelopmental disorders. Front Immunol. 2018;9:1993.
   PubMed Web of Science ®Google Scholar
• Sampson TR, and Mazmanian SK. control of brain development, function, and behavior by the microbiome. Cell Host Microbe. 2015;17(5): 565–576.
   PubMed Web of Science ®Google Scholar
• Robertson RC, Manges AR, and Finlay BB, et al. The human microbiome and child growth – first 1000 days and beyond. Trends Microbiol. 2019;27(2):131–147.
   PubMed Web of Science ®Google Scholar
• Borre YE, O’Keeffe GW, and Clarke G, et al. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol Med. 2014;20(9): 509–18.
   PubMed Web of Science ®Google Scholar
• McCarthy MM, Nugent BM, and Lenz KM. Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain. Nature Reviews Neuroscience. 2017;18(8):471–484
   PubMed Web of Science ®Google Scholar
• Braniste V, Al-Asmakh M, and Kowal C, et al. The gut microbiota influences blood-brain barrier permeability in mice. Sci Transl Med. 2014;6(263):263ra158.
   PubMed Web of Science ®Google Scholar
• Hoban AE, Stilling RM, and Ryan FJ, et al. Regulation of prefrontal cortex myelination by the microbiota. Transl Psychiatry. 2016;6:e774.
   PubMed Web of Science ®Google Scholar
• Thion MS, Ginhoux F, and Garel S. Microglia and early brain development: an intimate journey. Science. 2018;362(6411):185–189.
   PubMed Web of Science ®Google Scholar
• Clarke G, Grenham S, and Scully P, et al. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol Psychiatry. 2013;18(6): 666–73.
   PubMed Web of Science ®Google Scholar
• Heijtz RD, Wang S, Anuar F, et al. Normal gut microbiota modulates brain development and behavior. Proc Nat Acad Sci. 2011;108(7):3047–3052.
   PubMed Web of Science ®Google Scholar
• Thion MS, Low D, Silvin A, et al. microbiome influences prenatal and adult microglia in a sex-specific manner. Cell. 2018;174(1):172.
   PubMedGoogle Scholar
• Castillo-Ruiz A, Mosley M, and George AJ, et al. The microbiota influences cell death and microglial colonization in the perinatal mouse brain. Brain Behav Immun. 2018;67:218–229.
   PubMed Web of Science ®Google Scholar
• Erny D, Hrabě de Angelis AL, and Jaitin D, et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci. 2015;18:965–977.
   PubMed Web of Science ®Google Scholar
• Bercik P, Denou E, and Collins J, et al. the intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology. 2011;141(2): 599–609.
   PubMed Web of Science ®Google Scholar
• Neufeld KM, Kang N, and Bienenstock J, et al. Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterol Motility. 2011;23(3): 255–64.
   PubMed Web of Science ®Google Scholar
• Sudo N, Chida Y, and Aiba Y, et al. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol. 2004;558:263–275.
   PubMed Web of Science ®Google Scholar
• Patten DA, and Collett A. Exploring the immunomodulatory potential of microbial-associated molecular patterns derived from the enteric bacterial microbiota. Microbiology (United Kingdom). 2013;159:1535–1544.
   PubMed Web of Science ®Google Scholar
• Al Nabhani Z, Dulauroy S, and Marques R, et al., A weaning reaction to microbiota is required for resistance to immunopathologies in the adult. Immunity. 2019;50(5):1276–1288. .
   PubMed Web of Science ®Google Scholar
• Al Nabhani Z, Eberl G. Imprinting of the immune system by the microbiota early in life. Mucosal Immunol. 2020;13(2):183–189.
   PubMed Web of Science ®Google Scholar
• Bunker JJ, and Bendelac A. IgA Responses to Microbiota. Immunity. 2018;49(2): 211–224.
   PubMed Web of Science ®Google Scholar
• Fitzpatrick Z, Frazer G, Ferro A, et al. Gut-educated IgA plasma cells defend the meningeal venous sinuses. Nature. 2020;587(7834):472–476.
   PubMed Web of Science ®Google Scholar
• Deverman BE, Patterson PH. Cytokines and CNS Development. Neuron. 2009;64(1):61–78.
   PubMed Web of Science ®Google Scholar
• Vargas DL, Nascimbene C, Krishnan C, et al. Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann Neurol. 2005;57(1):67–81.
   PubMed Web of Science ®Google Scholar
• Fiorentino M, Sapone A, and Senger S, et al. Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders. Mol Autism. 2016;7:49.
   PubMed Web of Science ®Google Scholar
• Hui CW, St-Pierre A, and El Hajj H, et al. Prenatal immune challenge in mice leads to partly sex-dependent behavioral, microglial, and molecular abnormalities associated with schizophrenia. Front Mol Neurosci. 2018;11:13. .
   PubMed Web of Science ®Google Scholar
• Erny D, De Angelis ALH, Jaitin D, et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci. 2015;18(7):965–977.
   PubMed Web of Science ®Google Scholar
• Ratsika A, Codagnone MC, and O’Mahony S, et al., Priming for life: early life nutrition and the microbiota-gut-brain axis. Nutrients. 2021;13(2):423.
   PubMed Web of Science ®Google Scholar
• Chua RXY, Tay MJY, and Ooi DSQ, et al. Understanding the link between allergy and neurodevelopmental disorders: a current review of factors and mechanisms. Front Neurol. 2021;11:603571.
   PubMed Web of Science ®Google Scholar
• Liu AH, Jaramillo R, and Sicherer SH, et al. National prevalence and risk factors for food allergy and relationship to asthma: Results from the national health and nutrition examination survey 2005-2006. J Allergy Clin Immunol. 2010;126(4):798–806.
   PubMed Web of Science ®Google Scholar
• Tran MM, Lefebvre DL, and Dharma C, et al. Predicting the atopic march: Results from the Canadian healthy infant longitudinal development study. J Allergy Clin Immunol. 2018;141(2): 601–607.
   PubMed Web of Science ®Google Scholar
• Valenta R, Hochwallner H, and Linhart B, et al. Food allergies: The basics. Gastroenterology. 2015;148(6): 1120–1131.
   PubMed Web of Science ®Google Scholar
• Koplin JJ, Wake M, and Dharmage SC, et al. Cohort profile: the healthnuts study: Population prevalence and environmental/genetic predictors of food allergy. Int J Epidemiol. 2015;44(4): 1161–71.
   PubMed Web of Science ®Google Scholar
• Alduraywish SA, Lodge CJ, Vicendese D, et al. Sensitization to milk, egg and peanut from birth to 18 years: a longitudinal study of a cohort at risk of allergic disease. Pediatr Allergy Immunol. 2016;27(1):83–91.
   PubMed Web of Science ®Google Scholar
• Azad MB, Konya T, and Guttman DS, et al. Infant gut microbiota and food sensitization: associations in the first year of life. Clin Exp Allergy. 2015;45(3):632–43.
   PubMed Web of Science ®Google Scholar
• Abrahamsson TR, Jakobsson HE, and Andersson AF, et al. Low diversity of the gut microbiota in infants with atopic eczema. J Allergy Clin Immunol. 2012;129(2): 434–40.
   PubMed Web of Science ®Google Scholar
• Wang M, Karlsson C, and Olsson C, et al. Reduced diversity in the early fecal microbiota of infants with atopic eczema. J Allergy Clin Immunol. 2008;121(1):129–34.
   PubMed Web of Science ®Google Scholar
• Bisgaard H, Li N, Bonnelykke K, et al. Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age. J Allergy Clin Immunol. 2011;129(1):128.
   PubMedGoogle Scholar
• Tamana SK, Tun H, and Konya T, et al. Bacteroides-dominant gut microbiome of late infancy is associated with enhanced neurodevelopment. Gut Microbes in press. 2021;13(1): 1930875.
   Web of Science ®Google Scholar
• Meldrum SJ, D’Vaz N, and Dunstan JA, et al. Allergic disease in the first year of life is associated with differences in subsequent neurodevelopment and behaviour. Early Hum Dev. 2012;88(7): 567–73.
   PubMed Web of Science ®Google Scholar
• Slob EMA, Brew BK, Vijverberg SJH, et al. Early-life antibiotic use and risk of attention-deficit hyperactivity disorder and autism spectrum disorder: results of a discordant twin study. Int J Epidemiol. 2021;50(2):475–484.
   PubMed Web of Science ®Google Scholar
• Obiakor C V, Tun HM, and Bridgman SL, et al. The association between early life antibiotic use and allergic disease in young children: recent insights and their implications. Expert Rev Clin Immunol. 2018;14(10):841–855.
   PubMed Web of Science ®Google Scholar
• Patrick DM, Sbihi H, and Dai DLY, et al. Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies. Lancet Respir Med. 2020;8(11):1094–1105.
   PubMed Web of Science ®Google Scholar
• Netea SA, Messina NL, and Curtis N. Early-life antibiotic exposure and childhood food allergy: a systematic review. J Allergy Clin Immunol. 2019;144(5):1445–1448.
   PubMed Web of Science ®Google Scholar
• Kim H, Sitarik AR, and Woodcroft K, et al. Birth mode, breastfeeding, pet exposure, and antibiotic use: Associations with the gut microbiome and sensitization in children. Curr Allergy Asthma Rep. 2019;19(4):22.
   PubMed Web of Science ®Google Scholar
• Milliken S, Allen RM, and Lamont RF. The role of antimicrobial treatment during pregnancy on the neonatal gut microbiome and the development of atopy, asthma, allergy and obesity in childhood. Expert Opin Drug Saf. 2019;18(3): 173–185.
   PubMed Web of Science ®Google Scholar
• Lamont RF, Møller Luef B, and Stener Jørgensen J. Childhood inflammatory and metabolic disease following exposure to antibiotics in pregnancy, antenatally, intrapartum and neonatally. F1000Res. 2020;9:F1000.
   PubMedGoogle Scholar
• Stokholm J, Sevelsted A, Bønnelykke K, et al. Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study. Lancet Respir Med. 2014;2(8):631–637.
   PubMed Web of Science ®Google Scholar
• van Daele E, Knol J, and Belzer C. Microbial transmission from mother to child: improving infant intestinal microbiota development by identifying the obstacles. Crit Rev Microbiol. 2019;45(5–6): 613–648.
   PubMed Web of Science ®Google Scholar
• Ting JY, Synnes A, Roberts A, et al. Association of antibiotic utilization and neurodevelopmental outcomes among extremely low gestational age neonates without proven sepsis or necrotizing enterocolitis. Am J Perinatol. 2018;35:972–978.
   PubMed Web of Science ®Google Scholar
• Aversa Z, Atkinson EJ, Schafer MJ, et al. Association of infant antibiotic exposure with childhood health outcomes. Mayo Clin Proc. 2021;96(1):66–77.
   PubMed Web of Science ®Google Scholar
• Hamad AF, Alessi-Severini S, and Mahmud SM, et al. Antibiotic exposure in the first year of life and the risk of attention-deficit/hyperactivity disorder: A population-based cohort study. Am J Epidemiol. 2019;188(11):1923–1931.
   PubMed Web of Science ®Google Scholar
• Mukhopadhyay S, Puopolo KM, and Hansen NI, et al. Impact of early-onset sepsis and antibiotic use on death or survival with neurodevelopmental impairment at 2 years of age among extremely preterm infants. Journal of Pediatrics. 2020;221:39–46.e5.
   PubMed Web of Science ®Google Scholar
• Sewell E, Roberts J, and Mukhopadhyay S. Association of infection in neonates and long-term neurodevelopmental outcome. Clin Perinatol. 2021;48(2):251–261.
   PubMed Web of Science ®Google Scholar
• Firestein MR, Myers MM, and Austin J, et al. Perinatal antibiotics alter preterm infant EEG and neurobehavior in the family nurture intervention trial. Dev Psychobiol. 2019;61(5):661–669. .
   PubMed Web of Science ®Google Scholar
• Axelsson PB, Clausen TD, and Petersen AH, et al., Investigating the effects of cesarean delivery and antibiotic use in early childhood on risk of later attention deficit hyperactivity disorder. J Child Psychol Psychiat Allied Discipline. 2019;60(2):151–159.
   PubMed Web of Science ®Google Scholar
• Lavebratt C, Yang LL, and Giacobini MB, et al., Early exposure to antibiotic drugs and risk for psychiatric disorders: a population-based study. Transl Psychiatry. 2019;9(1):317.
   PubMedGoogle Scholar
• Hickey MK, Miller NC, and Haapala J, et al. Infants exposed to antibiotics after birth have altered recognition memory responses at one month of age. Pediatr Res. 2021;89(6): 1500–1507.
   PubMed Web of Science ®Google Scholar
• Lu-Culligan A, Iwasaki A. the role of immune factors in shaping fetal neurodevelopment. Annu Rev Cell Dev Biol. 2020;36(1):441–468.
   PubMedGoogle Scholar
• Patel S, Cooper MN, and Jones H, et al. Maternal immune-related conditions during pregnancy may be a risk factor for neuropsychiatric problems in offspring throughout childhood and adolescence. Psychol Med. 2020;1–11.
   Web of Science ®Google Scholar
• Jain S, Baer RJ, McCulloch CE, et al. Association of maternal immune activation during pregnancy and neurologic outcomes in offspring. J Pediatr. 2021;238:87–93.e3.
   PubMed Web of Science ®Google Scholar
• Jensen A, A. F. Simões E, Bohn Christiansen C, et al. Respiratory syncytial virus and influenza hospitalizations in Danish children 2010–2016. Vaccine. 2021;39(30):4126–4134.
   PubMed Web of Science ®Google Scholar
• Raymond SL, Rincon JC, and Wynn JL, et al. Impact of Early-Life Exposures to Infections. Antibiotics, and Vaccines on Perinatal and Long-term Health and Disease. Frontiers in Immunology. 2017;8:729.
   Google Scholar
• Chawes BL, Stokholm J, and Schoos A-M-M, et al. Allergic sensitization at school age is a systemic low-grade inflammatory disorder. Allergy. 2017;72(7):1073–1080.
   PubMed Web of Science ®Google Scholar
• Bervoets L, van Hoorenbeeck K, and Kortleven I, et al. Differences in gut microbiota composition between obese and lean children: a cross-sectional study. Gut Pathog. 2013;5(1):10.
   PubMedGoogle Scholar
• West CE, Rydén P, and Lundin D, et al. Gut microbiome and innate immune response patterns in ige-associated eczema. Clin Exp Allergy. 2015;45(9):1419–29.
   PubMed Web of Science ®Google Scholar
• Slykerman RF, Kang J, van Zyl N, et al. Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo-controlled trial. Acta Paediatrica. 2018;107(12):2172–2178.
   PubMed Web of Science ®Google Scholar
• Thion MS, Low D, and Silvin A, et al. Microbiome influences prenatal and adult microglia in a sex-specific manner. Cell. 2018;172(3):500–516.e16.
   PubMed Web of Science ®Google Scholar
• Dunlop AL, Knight AK, Satten GA, et al. Stability of the vaginal, oral, and gut microbiota across pregnancy among African American women: the effect of socioeconomic status and antibiotic exposure. PeerJ. 2019;7:e8004.
   PubMed Web of Science ®Google Scholar
• Phoonlapdacha P, Tangshewinsirikul C, Phosuwattanakul J, et al. Gut microbiome profiles in Thai healthy pregnant women and its association with types of foods. BMC Pregnancy Childbirth. 2022;22(1):79.
   PubMed Web of Science ®Google Scholar
• Schmidt KM, Haddad EN, Sugino KY, et al. Dietary and plasma carotenoids are positively associated with alpha diversity in the fecal microbiota of pregnant women. J Food Sci. 2021;86(2):602–613.
   PubMed Web of Science ®Google Scholar
• Mandal S, Godfrey KM, McDonald D, et al. Fat and vitamin intakes during pregnancy have stronger relations with a pro-inflammatory maternal microbiota than does carbohydrate intake. Microbiome. 2016;4(1):55.
   PubMedGoogle Scholar
• Harrison PJ, Dunn TM, Campopiano DJ. Sphingolipid biosynthesis in man and microbes. Nat Prod Rep. 2018;35(9):921–954.
   PubMed Web of Science ®Google Scholar
• Johnson EL, Heaver SL, and Waters JL, et al. Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels. Nat Commun. 2020;11:2471.
   PubMed Web of Science ®Google Scholar
• Hussain G, Wang J, and Rasul A, et al. Role of cholesterol and sphingolipids in brain development and neurological diseases. Lipids Health Dis. 2019;18(1):26.
   PubMedGoogle Scholar
• Brink LR, Mercer KE, and Piccolo BD, et al. Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula. Am J Clin Nutr. 2020;111(6): 1190–1202.
   PubMed Web of Science ®Google Scholar
• Deoni S, Dean D, and Joelson S, et al. Early nutrition influences developmental myelination and cognition in infants and young children. Neuroimage. 2018;178:649–659.
   PubMed Web of Science ®Google Scholar
• Lee-Sarwar K, Kelly RS, and Lasky-Su J, et al. Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy. J Allergy Clin Immunol. 2018;142(1):335–338.e9.
   PubMed Web of Science ®Google Scholar
• Shaterian N, Abdi F, Ghavidel N, et al. Role of cesarean section in the development of neonatal gut microbiota: a systematic review. Open Med. 2021;16(1):624–639.
   Web of Science ®Google Scholar
• Galazzo G, van Best N, and Bervoets L, et al. Development of the microbiota and associations with birth mode, diet, and atopic disorders in a longitudinal analysis of stool samples, collected from infancy through early childhood. Gastroenterology. 2020;158(6): 1584–1596.
   PubMed Web of Science ®Google Scholar
• Bergstrom A, Skov TH, and Bahl MI, et al. Establishment of Intestinal microbiota during early life: a longitudinal, explorative study of a large cohort of Danish infants. Appl Environ Microbiol. 2014;80(9): 2889–900.
   PubMed Web of Science ®Google Scholar
• Carlson AL, Xia K, and Azcarate-Peril MA, et al. Infant gut microbiome associated with cognitive development. Biol Psychiatry. 2018;83(2):148–159.
   PubMed Web of Science ®Google Scholar
• Victora CG, Bahl R, Barros AJD, et al. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Lancet. 2016;387(10017):475–490.
   PubMed Web of Science ®Google Scholar
• Shi T, Ooi Y, and Zaw EM, et al. Association between respiratory syncytial virus-associated acute lower respiratory infection in early life and recurrent wheeze and asthma in later childhood. J Infect Dis. 2020;222(Suppl 7):S628–S633.
   PubMedGoogle Scholar
• Brasfield J, Goulding SM, and Kancherla V. Duration of breast feeding and attention-deficit/hyperactivity disorder in United States preschool-aged children. Res Dev Disabil. 2021;115:103995.
   PubMed Web of Science ®Google Scholar
• Plunkett BA, Mele L, and Casey BM, et al. Association of breastfeeding and child iq score at age 5 years. Obstetrics Gynecol. 2021;138(1): 135.
   PubMedGoogle Scholar
• Keim SA, Sullivan JA, and Sheppard K, et al. Feeding infants at the breast or feeding expressed human milk: Long-term cognitive, executive function, and eating behavior outcomes at age 6 years. J Pediatr. 2021;233:66–73.e1.
   PubMed Web of Science ®Google Scholar
• Herman DR, Rhoades N, and Mercado J, et al. Dietary habits of 2- to 9-year-old American children are associated with gut microbiome composition. J Acad Nutr Diet. 2020;120(4):517–534.
   PubMed Web of Science ®Google Scholar
• Hamad AF, Alessi-Severini S, Mahmud SM, et al. Early childhood antibiotics use and autism spectrum disorders: a population-based cohort study. Int J Epidemiol. 2018;47(5):1497–1506.
   PubMed Web of Science ®Google Scholar
• Slykerman RF, Coomarasamy C, Wickens K, et al. Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age. Psychopharmacology (Berl). 2019;236(5):1573–1582.
   PubMed Web of Science ®Google Scholar
• Slykerman RF, Thompson J, Waldie KE, et al. Antibiotics in the first year of life and subsequent neurocognitive outcomes. Acta Paediatrica. 2017;106(1):87–94.
   PubMed Web of Science ®Google Scholar
• Wickens K, Black PN, and Stanley T V, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2008;122(4): 788–794.
   PubMed Web of Science ®Google Scholar
• Welch MG, Halperin MS, Austin J, et al. Depression and anxiety symptoms of mothers of preterm infants are decreased at 4 months corrected age with family nurture intervention in the NICU. Arch Women’s Mental Health. 2016;19(1):51–61.
   PubMed Web of Science ®Google Scholar