Effects of deoxynivalenol and sodium meta-bisulphite on nutrient digestibility in growing pigs

References

• [ACIA] Agence canadienne d’inspection des aliments. 2015. Mycotoxines dans les aliments du bétail. [accessed 2019 March 15]. http://www.inspection.gc.ca/animaux/aliments-du-betail/directives-reglementaires/rg-8/fra/1347383943203/1347384015909?chap=1.
   Google Scholar
• Adeola O. 2001. Digestion and balance techniques in pigs. In: Lewis AJ, Southern LL, editors. Swine nutrition. Washington DC: CRC Press; p. 903–916.
   Google Scholar
• [AOAC] Association of Official Analytical Chemists. 2016. Official methods of analysis. Arlington (VA): AOAC.
   Google Scholar
• Avantaggiato G, Havenaar R, Visconti A. 2004. Evaluation of the intestinal absorption of deoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy of activated carbon and other adsorbent materials. Food Chem Toxicol. 42:817–824.
   Google Scholar
• Awad WA, Vahjen JR, Aschenbach A, Zentek J. 2011. A diet naturally contaminated with the Fusarium mycotoxin deoxynivalenol (DON) downregulates gene expression of glucose transporters in the intestine of broiler chickens. Livest Sci. 140:72–79.
   Google Scholar
• Bergsjo B, Langseth W, Nafstad I, Hogset Jansen J, Larsen HJS. 1993. The effects of naturally deoxynivalenol contaminated oats on the clinical condition, blood parameters, performance and carcass composition of growing pigs. Vet Res Commun. 17:283–294.
   Google Scholar
• Beyer M, Dänicke S, Rohweder D, Humpf HU. 2010. Determination of deoxynivalenol sulfonate (DONS) in cereals by hydrophilic interaction chromatography coupled to tandem mass spectrometry. Mycotox Res. 26:109–117.
   Google Scholar
• Canale A, Valente ME, Ciotti A. 1984. Determination of volatile carboxylic acids (C1-C5i) and lactic acid in aqueous acid extracts of silage by high performance liquid chromatography. J Sci Food Agric. 35:1178–1182.
   Google Scholar
• [CCAC] Canadian Council on Animal Care. 2009. CCAC guidelines on: the care and useof farm animals in research, teaching and testing. [accessed 2019 March 15]. https://www.ccac.ca/Documents/Standards/Guidelines/Farm_Animals.pdf.
   Google Scholar
• Dänicke S, Hegewald AK, Kahlert S, Kluess J, Rothkötter HJ, Breves G, Döll S. 2010. Studies on the toxicity of deoxynivalenol (DON), sodium metabisulfite, DON-sulfonate (DONS) and de-epoxy-DON for porcine peripheral blood mononuclear cells and the intestinal porcine epithelial cell lines IPEC-1 and IPEC-J2, and on effects of DON and DONS on piglets. Food Chem Toxicol. 48:2154–2162.
   Google Scholar
• Dänicke S, Kersten S, Valenta H, Breves G. 2012. Inactivation of deoxynivalenol-contaminated cereal grains with sodium metabisulfite: a review of procedures and toxicological aspects. Mycotox Res. 28:199–218.
   Google Scholar
• Dänicke S, Valenta H, Döll S. 2004. On the toxicokinetics and metabolism of deoxynivalenol (DON) in pig. Arch Anim Nutr. 58:169–180.
   Google Scholar
• Dänicke S, Valenta H, Gareis M, Lucht HW, von Reichenbach H. 2005. On the effect of a hydrothermal treatment of deoxynivalenol (DON)-contaminated wheat in the presence of sodium metabisulfite (Na2S2O5) on DON reduction and piglet performance. Anim Feed Sci Technol. 118:93–108.
   Google Scholar
• Dietrich B, Neuenschwander S, Bucher B, Wenk C. 2012. Fusarium mycotoxin-contaminated wheat containing deoxynivalenol alters the gene expression in the liver and the jejunum of broilers. Animal. 6:78–91.
   Google Scholar
• Eriksen GS, Pettersson H, Lindberg JE. 2003. Absorption, metabolism and excretion of 3-acetyl DON in pigs. Arch Anim Nutr. 57:335–345.
   Google Scholar
• Frobose HL, Fruge ED, Tokach MD, Hansen EL, DeRouchey JM, Dritz SS, Goodband RD, Nelson JL. 2015. The effects of deoxynivalenol-contaminated corn dried distillers grains with solubles in nursery pig diets and potential for mitigation by commercially available feed additives. J Anim Sci. 93:1074–1088.
   Google Scholar
• Ghareeb K, Awad WA, Böhm J, Zebeli Q. 2015. Impacts on the feed contaminant deoxynivalenol on the intestine of monogastric animals: poultry and swine. J Appl Toxicol. 35:327–337.
   Google Scholar
• González-Vega JC, Stein HH. 2014. Invited review - calcium digestibility and metabolism in pigs. Asian-Australas J Anim Sci. 27:1–9.
   Google Scholar
• Goyarts T, Dänicke S. 2005. Effects of deoxynivalenol (DON) on growth performance, nutrient digestibility and DON metabolism in pigs. Mycotox Res. 21:139–142.
   Google Scholar
• Guay F, Donovan SM, Trottier NL. 2006. Biochemical and morphological developments are partially impaired in intestinal mucosa from growing pigs fed reduced-protein diets supplemented with crystalline amino acids. J Anim Sci. 84:1749–1760.
   Google Scholar
• Huwig A, Freimund S, Käppeli O, Dutler H. 2001. Mycotoxin detoxication of animal feed by different adsorbents. Toxicol Lett. 122:179–188.
   Google Scholar
• Jard G, Liboz T, Mathieu F, Guyonvarc’h A, Lebrihi A. 2011. Review of mycotoxin reduction in food and feed: from prevention in the field to detoxification by adsorption or transformation. Food Addit Contam. 8:1590–1609.
   Google Scholar
• Jo H, Kong C, Song M, Kim BG. 2016. Effects of dietary deoxynivalenol and zearalenone on apparent ileal digestibility of amino acids in growing pigs. Anim Feed Sci Technol. 19:77–82.
   Google Scholar
• Kollarczik B, Gareis M, Hanelt M. 1994. In vitro transformation of the Fusarium mycotoxins deoxynivalenol and zearalenone by the normal gut microflora of pigs. Nat Toxins. 2:105–110.
   Google Scholar
• Kong C, Shin SY, Park CK, Kim BG. 2015. Effects of feeding barley naturally contaminated with Fusarium mycotoxins on growth performance, nutrient digestibility, and blood chemistry of gilts and growth recoveries by feeding a non-contaminated diet. Asian Australas J Anim. 29:662–670.
   Google Scholar
• Le Thanh BV, Lessard M, Chorfi Y, Guay F. 2015. The efficacy of anti-mycotoxin feed additives in preventing the adverse effects of wheat naturally contaminated with Fusarium mycotoxins on performance, intestinal barrier function and nutrient digestibility and retention in weanling pigs. Can J Anim Sci. 95:197–209.
   Google Scholar
• Lun AK, Young LG, Lumsden JH. 1985. The effects of vomitoxin and feed intake on the performance and blood characteristics of young pigs. J Anim Sci. 61:1178–1185.
   Google Scholar
• Maresca M, Mahfoud R, Garmy N, Fantini J. 2002. The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. J Nutr. 132:2723–2731.
   Google Scholar
• Myers WD, Ludden PA, Nayigihugu V, Hess BW. 2004. Technical note: A procedure for the preparation and quantitative analysis of samples for titanium dioxide. J Anim Sci. 82:179–183.
   Google Scholar
• Patience JF, Myers AJ, Ensley S, Jacobs BM, Madson D. 2014. Evaluation of two mycotoxin mitigation strategies in grow-finish swine diets contaning corn dried distillers grains with solubles naturally contaminated woth deoxynivalenol. J Anim Sci. 92:620–626.
   Google Scholar
• Pinton P, Braicu C, Nougayrède JP, Laffitte J, Taranu I, Oswald IP. 2010. Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism. J Nutr. 140:1956–1962.
   Google Scholar
• Pinton P, Nougayrède J-P, Del Rio J-C, Moreno C, Marin DE, Ferrier L, Bracarense A-P, Kolf-Clauw M, Oswald IP. 2009. The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression. Toxicol Appl Pharm. 237:41–48.
   Google Scholar
• Pinton P, Tsybulskyy D, Lucioli J, Laffitte J, Callu P, Lyazhri F, Grosjean F, Bracarense AP, Kolf-Clauw M, Oswald IP. 2012. Toxicity of deoxynivalenol and its acetylated derivatives on the intestine: differential effects on morphology, barrier function, tight junction proteins, and mitogen-activated protein kinases. Toxicol Sci. 130:180–190.
   Google Scholar
• Piotrowska M, Sliżewska K, Nowak A, Zielonka L, Zakowska Z, Gajęcka M, Gajęcki M. 2014. The effect of experimental fusarium mycotoxicosis on microbiota diversity in porcine ascending colon contents. Toxins. 6:2064–2081.
   Google Scholar
• Rotter BA. 1996. Invited review: toxicology of deoxynivalenol (vomitoxin). J Toxicol Env Health. 48:1–34.
   Google Scholar
• Schwartz HE, Hametner C, Slavik V, Greitbauer O, Bichl G, Kunz-Vekiru E, Schatzmayr D, Berthiller F. 2013. Characterization of three deoxynivalenol sulfonates formed by reaction of deoxynivalenol with sulfur reagents. J Agr Food Chem. 61:8941–8948.
   Google Scholar
• Selle PH, Truong HH, McQuade LR, Moss AF, Liu SY. 2016. Reducing agent and exogenous protease additions, individually and in combination, to wheat- and sorghum-based diets interactively influence parameters of nutrient utilisation and digestive dynamics in broiler chickens. Anim Nutr. 2:303–311.
   Google Scholar
• Sobrova P, Adam V, Vasatkova A, Beklova M, Zeman L, Kizek R. 2010. Deoxynivalenol and its toxicity. Interdisc Toxicol. 3:94–99.
   Google Scholar
• Spindler HK, Mosenthin R, Eklund M. 2014. Evaluation through literature data on standardized ileal digestibility and basal ileal endogenous loss of amino acids associated with barley in pigs. Animal. 8:1603–1611.
   Google Scholar
• Stein HH, Sève B, Fuller MF, Moughan PJ, de Lange CFM. 2007. Invited review: amino acid bioavailability and digestibility in pig feed ingredients: terminology and application. J Anim Sci. 85:172–180.
   Google Scholar
• Streit E, Naehrer K, Rodrigues I, Schatzmayr G. 2013. Mycotoxin occurrence in feed and feed raw materials worldwide: long-term analysis with special focus on Europe and Asia. J Sci Food Agric. 93:2892–2899.
   Google Scholar
• Topping DL, Clifton PM. 2001. Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev. 81:1031–1064.
   Google Scholar
• Trenholm HL, Prelusky DB, Young JC, Miller JD. 1988. Reducing mycotoxins in animal feeds. Ottawa (ON): Agriculture Canada publication 1827E.
   Google Scholar
• Truong HH, Neilson KA, McInerney KA, Khoddami A, Roberts TH, Liu SY, Selle PH. 2016. Sodium metabisulfite enhances energy utilisation in broiler chickens offered sorghum-based diets with five different grain varieties. Anim Feed Sci Technol. 219:159–174.
   Google Scholar
• Valenta H, Dänicke S, Döll S. 2003. Analysis of deoxynivalenol and de-epoxydeoxynivalenol in animal tissues by liquid chromatography after clean-up with an immunoaffinity column. Mycotox Res. 19:51–55.
   Google Scholar
• Waché YJ, Valat C, Postollec G, Bougeard S, Burel C, Oswald IP, Fravalo P. 2009. Impact of deoxynivalenol on the intestinal microflora of pigs. Int J Mol Sci. 10:1–17.
   Google Scholar
• Wu L, Liao P, He L, Ren W, Yin J, Duan J, Li T. 2015. Growth performance, serum biochemical profile, jejunal morphology, and the expression of nutrients transporter genes in deoxynivalenol (DON)- challenged growing pigs. BMC Vet Res. 11:144–154.
   Google Scholar
• Wubben JE, Smiricky MR, Albin DM, Gabert VM. 2001. Improved procedure and cannula design for simple-T cannulation at the distal ileum in growing pigs. Contemp Top Lab Anim Sci. 40:27–31.
   Google Scholar