341
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Response of gastrointestinal fermentative activity and colonic microbiota to protected sodium butyrate and protected sodium heptanoate in weaned piglets challenged with ETEC F4+

ORCID Icon, ORCID Icon, ORCID Icon, , , & ORCID Icon show all
Pages 339-359 | Received 26 Feb 2019, Accepted 05 Jul 2019, Published online: 25 Jul 2019

References

  • [AOAC] Association of Official Analytical Chemists. 2007. Official methods of analysis of AOAC International. 18th ed. Gaithersburg (MD): Association of Official Analytical Chemists.
  • Barba-Vidal E, Castillejos L, López-Colom P, Rivero Urgell M, Moreno Muñoz JA, Martín-Orúe SM. 2017. Evaluation of the probiotic strain Bifidobacterium longum subsp. infantis CECT 7210 capacities to improve health status and fight digestive pathogens in a piglet model. Front Microbiol. 8:533.
  • Barrow PA, Fuller R, Newport MJ. 1977. Changes in the microflora and physiology of the anterior intestinal tract of pigs weaned at 2 days, with special reference to the pathogenesis of diarrhea. Infect Immun. 18:586–595.
  • Bates D, Maechler M, Bolker B, Walker S. 2015. Fitting linear mixed-effects models using lme4. J Stat Softw. 67:1–48.
  • Biagi G, Piva A, Moschini M, Vezzali E, Roth FX. 2007. Performance, intestinal microflora, and wall morphology of weanling pigs fed sodium butyrate. J Anim Sci. 85:1184–1191.
  • Bokulich NA, Subramanian S, Faith JJ, Gevers D, Gordon JI, Knight R, Mills DA, Caporaso JG. 2013. Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing. Nat Methods. 10:57–59.
  • Bugaut M. 1987. Occurrence, absorption and metabolism of short chain fatty acids in the digestive tract of mammals. Comp Biochem Physiol. B. 86:439–472.
  • Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, Fierer N, Peña AG, Goodrich JK, Gordon JI, et al. 2010. QIIME allows analysis of high-throughput community sequencing data. Nat Methods. 7:335–336.
  • Castillo M, Martín-Orúe SM, Roca M, Manzanilla EG, Badiola I, Pérez JF, Gasa J. 2006. The response of gastrointestinal microbiota to avilamycin, butyrate, and plant extracts in early-weaned pigs. J Anim Sci. 84:2725–2734.
  • De Smet S, Michiels J, Ovyn A, Dierick N, Laget M, Cools A, Lauwaerts A. 2016. Gut antibacterial effects of C7 and C9 carboxylic acids in the diet of piglets. J Anim Sci. 94:54–57.
  • DeSantis TZ, Hugenholtz P, Larsen N, Rojas M, Brodie EL, Keller K, Huber T, Dalevi D, Hu P, Andersen GL. 2006. Greengenes, a chimera-checked 16s rRNA gene database and workbench compatible with ARB. Appl Environ Microbiol. 72:5069–5072.
  • Dierick N, Michiels J, Van Nevel C. 2004. Effect of medium chain fatty acids and benzoic acid, as alternatives for antibiotics, on growth and some gut parameters in piglets. Commun Agric Appl Biol Sci. 69:187–190.
  • Edmonds MS, Izquierdo OA, Baker DH. 1985. Feed additive studies with newly weaned pigs: efficacy of supplemental copper, antibiotics and organic acids. J Anim Sci. 60:462–469.
  • EFSA and ECDC. 2017 Feb 23. The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2015. EFSA Journal. doi:10.2903/j.efsa.2017.4694
  • Fairbrother JM, Nadeau E, Gyles CL. 2005. Escherichia coli in postweaning diarrhea in pigs: an update on bacterial types, pathogenesis, and prevention strategies. Anim Health Res Rev. 6:17–39.
  • Grilli E, Vitari F, Domeneghini C, Palmonari A, Tosi G, Fantinati P, Massi P, Piva A. 2012. Development of a feed additive to reduce caecal Campylobacter jejuni in broilers at slaughter age: from in vitro to in vivo, a proof of concept. J Appl Microbiol. 114:308–317.
  • Haas BJ, Gevers D, Earl AM, Feldgarden M, Ward DV, Giannoukos G, Ciulla D, Tabbaa D, Highlander SK, Sodergren E, et al. 2011. Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons. Genome Res. 21:494–504.
  • Hermes RG, Molist F, Pérez JF, Gómez de Segura A, Ywazaki M, Davin R, Nofrarías M, Korhonen TK, Virkola R, Martín-Orúe SM. 2013. Casein glycomacropeptide in the diet may reduce Escherichia coli attachment to the intestinal mucosa and increase the intestinal lactobacilli of early weaned piglets after an enterotoxigenic E. coli K88 challenge. Br J Nutr. 109:1001–1012.
  • Holman D, Brunelle B, Trachsel J, Allen H. 2017. Meta-analysis to define a core microbiota in the swine gut. mSystems. 2:e00004–17.
  • Hothorn T, Bretz F, Westfall P. 2008. Simultaneous inference in general parametric models. Biometrical J. 50:346–363.
  • Jensen MT, Cox RP, Jensen BB. 1995. Microbial production of skatole in the hind gut of pigs given different diets and its relation to skatole deposition in backfat. Anim Sci. 61:293–304.
  • Leatham M, Banerjee S, Autieri S, Mercado-Lubo R, Conway T, Cohen P. 2009. Precolonized human commensal Escherichia coli strains serve as a barrier to E. coli O157: H7 growth in the streptomycin-treated mouse intestine. Infect Immun. 77:2876–2886.
  • Lu JJ, Zou XT, Wang YM. 2008. Effects of sodium butyrate on the growth performance, intestinal flora and morphology of weanling pigs. J Anim Feed Sci. 17:568–578.
  • Mach N, Berri M, Estellé J, Levenez F, Lemonnier G, Denis C, Leplat JJ, Chevaleyre C, Billon Y, Doré J, et al. 2015. Early-life establishment of the swine gut microbiome and impact on host phenotypes. Environ Microbiol Rep. 7:554–569.
  • Mann E, Schmitz-Esser S, Zebeli Q, Wagner M, Ritzmann M, Metzler-Zebeli BU. 2014. Mucosa-associated bacterial microbiome of the gastrointestinal tract of weaned pigs and dynamics linked to dietary calcium-phosphorus. PLoS One. 9:e86950.
  • Manzanilla EG, Nofrarías M, Anguita M, Castillo M, Pérez JF, Martín-Orúe SM, Kamel C, Gasa J. 2006. Effects of butyrate, avilamycin, and a plant extract combination on the intestinal equilibrium of early-weaned pigs. J Anim Sci. 84:2743–2751.
  • McMurdie PJ, Holmes S. 2013. Phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PLoS One. 8:e61217.
  • Melo ADB, Silveira H, Bortoluzzi C, Lara LJ, Garbossa CAP, Preis G, Costa LB, Rostagno MH. 2016. Intestinal alkaline phosphatase and sodium butyrate may be beneficial in attenuating LPS-induced intestinal inflammation. Gen Mol Res. 15. doi:10.4238/gmr15048875
  • Metzler-Zebeli BU, Zijlstra RT, Mosenthin R, Gänzle MG. 2011. Dietary calcium phosphate content and oat β-glucan influence gastrointestinal microbiota, butyrate-producing bacteria and butyrate fermentation in weaned pigs. FEMS Microbiol Ecol. 75:402–413.
  • Nofrarías M, Manzanilla EG, Pujols J, Gibert X, Majó N, Segalés J, Gasa J. 2006. Effects of spray-dried porcine plasma and plant extracts on intestinal morphology and on leukocyte cell subsets of weaned pigs. J Anim Sci. 84:2735–2742.
  • [NRC] National Research Council. 2012. Nutrient requirements of swine: eleventh revised edition. Washington (DC): National Academies Press.
  • Petri D, Hill J, van Kessel A. 2010. Microbial succession in the gastrointestinal (GIT) of the preweaned pig. Livest Sci. 133:107–109.
  • Piñeiro C, Piñeiro M, Morales J, Andrés M, Lorenzo E, Pozo MD, Alava MA, Lampreave F. 2009. Pig-MAP and haptoglobin concentration reference values in swine from commercial farms. Vet J. 179:78–84.
  • R Core Team. 2013. R: A language and environment for statistical computing. Vienna (AT): R Foundation for Statistical Computing.
  • Richardson AJ, Calder AG, Stewart CS, Smith A. 1989. Simultaneous determination of volatile and non-volatile acidic fermentation products of anaerobes by capillary gas chromatography. Lett Appl Microbiol. 9:5–8.
  • Rideout J, He Y, Navas-Molina JA, Walters WA, Ursell LK, Gibbons SM, Chase J, McDonald D, Gonzalez A, Robbins-Pianka A, et al. 2014. Subsampled open-reference clustering creates consistent, comprehensive OTU definitions and scales to billions of sequences. PeerJ. 2:e545.
  • Ríos-Covián D, Ruas-Madiedo P, Margolles A, Gueimonde M, de los Reyes-Gavilán CG, Salazar N. 2016. Intestinal short chain fatty acids and their link with diet and human health. Front Microbiol. 7:185.
  • Soler C, Goossens T, Bermejo A, Migura-García L, Cusco A, Francino O, Fraile L. 2018. Digestive microbiota is different in pigs receiving antimicrobials or a feed additive during the nursery period. PLoS One. doi:10.1371%2Fjournal.pone.0197353
  • Tsiloyiannis VK, Kyriakis SC, Vlemmas J, Sarris K. 2001. The effect of organic acids on the control of porcine post-weaning diarrhoea. Res Vet Sci. 70:287–293.
  • Van Soest PJ, Robertson JB, Lewis BA. 1991. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J Dairy Sci. 74:3583–3597.
  • Venables WN, Ripley BD. 2002. Modern applied statistics with S. 4th ed. New York (NY): Springer.
  • Xu J, Chen X, Yu S, Su Y, Zhu W. 2016. Effects of early intervention with sodium butyrate on gut microbiota and the expression of inflammatory cytokines in neonatal piglets. PLoS One. 19:e0162461.
  • Zeileis A, Kleiber C, Jackman S. 2008. Regression models for count data in R. J Stat Softw. 27. doi:10.18637/jss.v027.i08
  • Zentek J, Buchheit-Renko S, Männer K, Pieper R, Vahjen W. 2012. Intestinal concentrations of free and encapsulated dietary medium-chain fatty acids and effects on gastric microbial ecology and bacterial metabolic products in the digestive tract of piglets. Arch Anim Nutr. 66:4–26.
  • Zentek J, Ferrara F, Pieper R, Tedin L, Meyer W, Vahjen W. 2013. Effects of dietary combinations of organic acids and medium chain fatty acids on the gastrointestinal microbial ecology and bacterial metabolites in the digestive tract of weaning piglets. J Anim Sci. 91:3200–3210.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.