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Research Article

Effects of sanitary conditions with lipopolysaccharide injection and dietary valine supplementation on growth performance, immune response, bacterial profile, and microbial metabolites in weaned pigs

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Received 21 Nov 2023, Accepted 16 Jul 2024, Published online: 01 Aug 2024

References

  • Adewole DI, Kim IH, Nyachoti CM. 2016. Gut health of pigs: challenge models and response criteria with a critical analysis of the effectiveness of selected feed additives — a review. Asian Australas J Anim Sci. 29:909–924. doi: 10.5713/ajas.15.0795.
  • Arend WP, Malyak M, Guthridge CJ, Gabay C. 1998. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol. 16:27–55. doi: 10.1146/annurev.immunol.16.1.27.
  • Bröer S. 2008. Amino acid transport across mammalian intestinal and renal epithelia. Physiol Rev. 88:249–286. doi: 10.1152/physrev.00018.2006.
  • Brynestad S, Granum PE. 2002. Clostridium perfringens and foodborne infections. Int J Food Microbiol. 74:195–202. doi: 10.1016/S0168-1605(01)00680-8.
  • Chen XH, Liu SR, Peng B, Li D, Cheng ZX, Zhu JX, Zhang S, Peng YM, Li H, Zhang TT, et al. 2017. Exogenous L-valine promotes phagocytosis to kill multidrug-resistant bacterial pathogens. Front Immunol. 8:207. doi: 10.3389/fimmu.2017.00207.
  • Cho HM, González-Ortiz G, Melo-Durán D, Heo JM, Cordero G, Bedford MR, Kim JC, Blachier F. 2020. Stimbiotic supplementation improved performance and reduced inflammatory response via stimulating fiber fermenting microbiome in weaner pigs housed in a poor sanitary environment and fed an antibiotic-free low zinc oxide diet. PLOS ONE. 15:e0240264. doi: 10.1371/journal.pone.0240264.
  • Cremonesi P, Pisani LF, Lecchi C, Ceciliani F, Martino P, Bonastre AS, Karus A, Balzaretti C, Castiglioni B. 2014. Development of 23 individual TaqMan® real-time PCR assays for identifying common foodborne pathogens using a single set of amplification conditions. Food Microbiol. 43:35–40. doi: 10.1016/j.fm.2014.04.007.
  • Erwin ES, Marco GJ, Emery EM. 1961. Volatile fatty acid analyses of blood and rumen fluid by gas chromatography. J Dairy Sci. 44:1768–1771. doi: 10.3168/jds.S0022-0302(61)89956-6.
  • Escobar J, Frank JW, Suryawan A, Nguyen HV, Kimball SR, Jefferson LS, Davis TA. 2006. Regulation of cardiac and skeletal muscle protein synthesis by individual branched-chain amino acids in neonatal pigs. Am J Physiol-Endocrinol Metab. 290:E612–E621. doi: 10.1152/ajpendo.00402.2005.
  • Fahlgren A, Hammarstrom S, Danielsson A, Hammarstrom ML. 2003. Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis. Clin Exp Immunol. 131:90–101. doi: 10.1046/j.1365-2249.2003.02035.x.
  • Floc’h N L, Melchior D, Obled C. 2004. Modifications of protein and amino acid metabolism during inflammation and immune system activation. Livest Prod Sci. 87:37–45. doi: 10.1016/j.livprodsci.2003.09.005.
  • Giuliani A, Pirri G, Nicoletto S. 2007. Antimicrobial peptides: an overview of a promising class of therapeutics. Open Life Sci. 2:1–33. doi: 10.2478/s11535-007-0010-5.
  • Gloaguen M, Floc’h N L, Brossard L, Barea R, Primot Y, Corrent E, Van Milgen J. 2011. Response of piglets to the valine content in diet in combination with the supply of other branched-chain amino acids. Animal. 5:1734–1742. doi: 10.1017/S1751731111000760.
  • Harper AE, Miller R, Block KP. 1984. Branched-chain amino acid metabolism. Annu Rev Nutr. 4:409–454. doi: 10.1146/annurev.nu.04.070184.002205.
  • Heo JM, Kim JC, Hansen CF, Mullan BP, Hampson DJ, Pluske JR. 2010. Feeding a diet with a decreased protein content reduces both nitrogen content in the gastrointestinal tract and post-weaning diarrhoea, but does not affect apparent nitrogen digestibility in weaner pigs challenged with an enterotoxigenic strain of Escherichia coli. Anim Feed Sci Technol. 160:148–159. doi: 10.1016/j.anifeedsci.2010.07.005.
  • Hippe B, Zwielehner J, Liszt K, Lassl C, Unger F, Haslberger AG. 2011. Quantification of butyryl CoA: acetate CoA-transferase genes reveals different butyrate production capacity in individuals according to diet and age. FEMS Microbiol Lett. 316:130–135. doi: 10.1111/j.1574-6968.2010.02197.x.
  • Jaffer U, Wade RG, Gourlay T. 2010. Cytokines in the systemic inflammatory response syndrome: a review. HSR Proc Intensive Care Cardiovasc Anesth. 2:161–175.
  • Jayaraman B, Htoo JK, Nyachoti CM. 2017. Effects of different dietary tryptophan: lysine ratios and sanitary conditions on growth performance, plasma urea nitrogen, serum haptoglobin and ileal histomorphology of weaned pigs. Anim Sci J. 88:763–771. doi: 10.1111/asj.12695.
  • Leonel AJ, Alvarez-Leite JI. 2012. Butyrate: implications for intestinal function. Curr Opin Clin Nutr Metab Care. 15:474–479. doi: 10.1097/MCO.0b013e32835665fa.
  • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method. Methods. 25:402–408. doi: 10.1006/meth.2001.1262.
  • Montagne L, Floc’h N L, Arturo-Schaan M, Foret R, Urdaci MC, Le Gall M. 2012. Comparative effects of level of dietary fiber and sanitary conditions on the growth and health of weanling pigs. J Anim Sci. 90:2556–2569. doi: 10.2527/jas.2011-4160.
  • Montagne L, Pluske JR, Hampson DJ. 2003. A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young nonruminant animals. Anim Feed Sci Technol. 108:95–117. doi: 10.1016/S0377-8401(03)00163-9.
  • Mousavi KA, Abhari K, Eş I, Soares MB, Oliveira RBA, Hosseini H, Rezaei M, Balthazar CF, Silva R, Cruz AG, et al. 2020. Interactions between probiotics and pathogenic microorganisms in hosts and foods: a review. Trends Food Sci Techonol. 95:205–218. doi: 10.1016/j.tifs.2019.11.022.
  • National Research Council (NRC). 2012. Nutrient requirements of swine. 11th rev. ed. (Washington) D.C: The National Academy Press.
  • Nordgreen J, Munsterhjelm C, Aae F, Popova A, Boysen P, Ranheim B, Heinonen M, Raszplewicz J, Piepponen P, Lervik A, et al. 2018. The effect of lipopolysaccharide (LPS) on inflammatory markers in blood and brain and on behavior in individually-housed pigs. Physiol Behav. 195:98–111. doi: 10.1016/j.physbeh.2018.07.013.
  • Novozamsky I, Eck R, van Schouwenburg JC. 1974. Total nitrogen determination in plant material by means of the indophenol-blue method. Neth J Agric Sci. 22:3–5. doi: 10.18174/njas.v22i1.17230.
  • Pereira AM, Pinna C, Biagi G, Stefanelli C, Maia MR, Matos E, Segundo MA, Fonseca AJM, Cabrita ARJ. 2020. Supplemental selenium source on gut health: insights on fecal microbiome and fermentation products of growing puppies. FEMS Microbiol Ecol. 96:fiaa212. doi: 10.1093/femsec/fiaa212.
  • Qi M, Tan B, Wang J, Liao S, Deng Y, Ji P, Song T, Zha A, Yin Y. 2021. The microbiota–gut–brain axis: a novel nutritional therapeutic target for growth retardation. Crt Rev Food Sci Nutr. 62:4867–4892. doi: 10.1080/10408398.2021.1879004.
  • Remely M, Tesar I, Hippe B, Gnauer S, Rust P, Haslberger AG. 2015. Gut microbiota composition correlates with changes in body fat content due to weight loss. Benef Microbes. 6:431–439. doi: 10.3920/BM2014.0104.
  • Ren M, Zhang S, Liu X, Li S, Mao X, Zeng X, Qiao S. 2016. Different lipopolysaccharide branched-chain amino acids modulate porcine intestinal endogenous β-defensin expression through the Sirt1/ERK/90RSK pathway. J Agric Food Chem. 64:3371–3379. doi: 10.1021/acs.jafc.6b00968.
  • Sanchez NB, Carroll JA, Broadway PR, Bass BE, Frank JW. 2019. Supplementation of a Lactobacillus acidophilus fermentation product can attenuate the acute phase response following a lipopolysaccharide challenge in weaned pigs. Animal. 13:144–152. doi: 10.1017/S1751731118001222.
  • Semenov AV, van Overbeek L, Termorshuizen AJ, van Bruggen AH. 2011. Influence of aerobic and anaerobic conditions on survival of Escherichia coli O157: H7 and Salmonella enterica serovar Typhimurium in Luria–Bertani broth, farm-yard manure and slurry. J Environ Manage. 92:780–787. doi:10.1016/j.jenvman.2010.10.031.
  • Stiemsma LT, Reynolds LA, Turvey SE, Finlay BB. 2015. The hygiene hypothesis: current perspectives and future therapies. ImmunoTargets Ther. 4:143–157. doi: 10.2147/ITT.S61528.
  • Te Pas MFW, Jansman AJM, Kruijt L, van der Meer Y, Vervoort JJM, Schokker D. 2020. Sanitary conditions affect the colonic microbiome and the colonic and systemic metabolome of female pigs. Front Vet Sci. 7:585730. doi: 10.3389/fvets.2020.585730.
  • van der Meer Y, Lammers A, Jansman AJM, Rijnen MMJA, Hendriks WH, Gerrits WJJ. 2016. Performance of pigs kept under different sanitary conditions affected by protein intake and amino acid supplementation. J Anim Sci. 94:4704–4719. doi: 10.2527/jas.2016-0787.
  • Waititu SM, Yin F, Patterson R, Yitbarek A, Rodriguez-Lecompte JC, Nyachoti CM. 2017. Dietary supplementation with a nucleotide-rich yeast extract modulates gut immune response and microflora in weaned pigs in response to a sanitary challenge. Animal. 11:2156–2164. doi: 10.1017/S1751731117001276.
  • Wehkamp J, Schmid M, Stange EF. 2007. Defensins and other antimicrobial peptides in inflammatory bowel disease. Curr Opin Gastroenterol. 23:370–378. doi: 10.1097/MOG.0b013e328136c580.
  • Wessels AG, Kluge H, Hirche F, Kiowski A, Schutkowski A, Corrent E, Bartelt J, König B, Stangl GI, Clelland JD. 2016. High leucine diets stimulate cerebral branched-chain amino acid degradation and modify serotonin and ketone body concentrations in a pig model. PLOS ONE. 11:e0150376. doi: 10.1371/journal.pone.0150376.
  • Wu SB, Rodgers N, Choct M. 2011. Real-time PCR assay for Clostridium perfringens in broiler chickens in a challenge model of necrotic enteritis. Appl Environ Microbiol. 77:1135–1139. doi: 10.1128/AEM.01803-10.
  • Xu YT, Ma XK, Wang CL, Yuan MF, Piao XS. 2018. Effects of dietary valine: lysine ratio on the performance, amino acid composition of tissues and mRNA expression of genes involved in branched-chain amino acid metabolism of weaned piglets. Asian-Australas J Anim Sci. 31:106–115. doi: 10.5713/ajas.17.0148.
  • Zhang G, Ross CR, Blecha F. 2000. Porcine antimicrobial peptides: new prospects for ancient molecules of host defense. Vet Res. 31:277–296. doi: 10.1051/vetres:2000121.
  • Zhang S, Qiao S, Ren M, Zeng S, Ma X, Wu Z, Thacker P, Wu G. 2013. Supplementation with branched-chain amino acids to a low-protein diet regulates intestinal expression of amino acid and peptide transporters in weanling pigs. Amino Acids. 45:1191–1205. doi: 10.1007/s00726-013-1577-y.
  • Zhang S, Zeng X, Ren M, Mao X, Qiao S. 2017. Novel metabolic and physiological functions of branched chain amino acids: a review. J Anim Sci Biotechnol. 8:10. doi: 10.1186/s40104-016-0139-z.

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