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Acta Orthopaedica Volume 88, 2017 - Issue 5
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Articles

Higher risk of revision for infection using systemic clindamycin prophylaxis than with cloxacillin

A report from the Swedish Knee Arthroplasty Register on 78,000 primary total knee arthroplasties for osteoarthritis

Otto RobertssonThe Swedish Knee Arthroplasty Register, Lund University, Skåne University Hospital and Department of Clinical Sciences Lund, Orthopedics, Lund, Sweden; Correspondence[email protected]
,
Olof ThompsonDepartment of Infectious Diseases, Skåne University Hospital, Lund, Sweden
,
Annette W-DahlThe Swedish Knee Arthroplasty Register, Lund University, Skåne University Hospital and Department of Clinical Sciences Lund, Orthopedics, Lund, Sweden;
,
Martin SundbergThe Swedish Knee Arthroplasty Register, Lund University, Skåne University Hospital and Department of Clinical Sciences Lund, Orthopedics, Lund, Sweden;
,
Lars LidgrenThe Swedish Knee Arthroplasty Register, Lund University, Skåne University Hospital and Department of Clinical Sciences Lund, Orthopedics, Lund, Sweden;
&
Anna StefánsdóttirThe Swedish Knee Arthroplasty Register, Lund University, Skåne University Hospital and Department of Clinical Sciences Lund, Orthopedics, Lund, Sweden;
Pages 562-567 | Received 26 Feb 2017, Accepted 10 Apr 2017, Published online: 11 May 2017

  • Ahmed K A, Fox S J, Frigas E, Park M A. Clinical outcome in the use of cephalosporins in pediatric patients with a history of penicillin allergy. Int Arch Allergy Immunol 2012; 158(4): 405–10.
  • AlBuhairan B, Hind D, Hutchinson A. Antibiotic prophylaxis for wound infections in total joint arthroplasty: a systematic review. J Bone Joint Surg Br 2008; 90(7): 915–9.
  • de Beer J, Petruccelli D, Rotstein C, Weening B, Royston K, Winemaker M. Antibiotic prophylaxis for total joint replacement surgery: results of a survey of Canadian orthopedic surgeons. Can J Surg 2009; 52(6): E229–34.
  • Belmont P J, Goodman G P, Waterman B R, Bader J O, Schoenfeld A J. Thirty-day postoperative complications and mortality following total knee arthroplasty. J Bone Joint Surg Am 2014; 96(1): 20–6.
  • Borch J E, Andersen KE, Bindslev-Jensen C. The prevalence of suspected and challenge-verified penicillin allergy in a university hospital population. Basic Clin Pharmacol Toxicol 2006; 98(4): 357–62.
  • Bratzler D W, Dellinger E P, Olsen K M, Perl T M, Auwaerter P G, Bolon M K, Fish D N, Napolitano L M, Sawyer R G, Slain D, Steinberg J P, Weinstein R A. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Heal Pharm 2013; 70(3): 195–283.
  • Chandrananth J, Rabinovich A, Karahalios A, Guy S, Tran P. Impact of adherence to local antibiotic prophylaxis guidelines on infection outcome after total hip or knee arthroplasty. J Hosp Infect 2016; 93(4): 423–7.
  • Dorey F, Nasser S, Amstutz H. The need for confidence intervals in the presentation of orthopaedic data. J Bone Joint Surg Am 1993; 75(12): 1844–52.
  • Engesaeter L B, Lie S A, Espehaug B, Furnes O, Vollset S E, Havelin L I. Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register. Acta Orthop Scand 2003; 74(6): 644–51.
  • Ericson C, Lidgren L, Lindberg L. Cloxacillin in the prophylaxis of postoperative infections of the hip. J Bone Joint Surg Am 1973; 55(4): 808–13, 843.
  • Graves S, Steiger R De, Lewis P, Williams S, Bergman N, Cunningham J. The Australian Orthopaedic Association National Joint Arthroplasty Register. Hip and Knee Arthroplasty: Annual Report 2014; 1-235.
  • Hansen E, Belden K, Silibovsky R, Vogt M, Arnold W, Bicanic G, Bini S, Catani F, Chen J, Ghazavi M, Godefroy KM, Holham P, Hosseinzadeh H, Kim KI, Kirketerp-Møller K, Lidgren L, Lin JH, Lonner JH, Moore CC, Papagelopoulos P, Poultsides L, Randall RL, Roslund B, Saleh K, Salmon JV, Schwarz E, Stuyck J, Dahl AW, Yamada K. Perioperative antibiotics. J Orthop Res 2014; 32(S1): S31–S59.
  • Hickson CJ, Metcalfe D, Elgohari S, Oswald T, Masters J P, Rymaszewska M, Reed M R, Sprowson A P. Prophylactic antibiotics in elective hip and knee arthroplasty: an analysis of organisms reported to cause infections andnational survey of clinical practice. Bone Joint Res 2015; 4(11): 181–9.
  • Hill C, Flamant R, Mazas F, Evrard J. Prophylactic cefazolin versus placebo in total hip replacement. Report of a multicentre double-blind randomised trial. Lancet 1981; 1(8224): 795–6.
  • Holmberg A, Thórhallsdóttir V G, Robertsson O, W-Dahl A, Stefánsdóttir A. 75% success rate after open debridement, exchange of tibial insert, and antibiotics in knee prosthetic joint infections. Acta Orthop 2015; 86(4): 1–6.
  • Inacio M C S, Kritz-Silverstein D, Raman R, Macera C A, Nichols J F, Shaffer R A, Fithian D C. The impact of pre-operative weight loss on incidence of surgical site infection and readmission rates after total joint arthroplasty. J Arthroplasty 2014; 29(3): 458–64.
  • Jämsen E, Huhtala H, Puolakka T, Moilanen T. Risk factors for infection after knee arthroplasty. A register-based analysis of 43,149 cases. J Bone Joint Surg Am 2009; 91(1): 38–47.
  • Kapadia BH, Berg RA, Daley JA, Fritz J, Bhave A, Mont MA. Periprosthetic joint infection. Lancet. 2015; 6736(14): 1–9.
  • Macy E, Schatz M, Lin C, Poon K-Y. The falling rate of positive penicillin skin tests from 1995 to 2007. Perm J 2009; 13(2): 12–8.
  • McElroy M J, Pivec R, Issa K, Harwin S F, Mont M A. The effects of obesity and morbid obesity on outcomes in TKA. J Knee Surg 2013; 26(2): 83–8.
  • Meehan J, Jamali A A, Nguyen H. Prophylactic antibiotics in hip and knee arthroplasty. J Bone Joint Surg Am 2009; 91(10): 2480–90.
  • Mirakian R, Leech SC, Krishna M T, Richter A G, Huber P A J, Farooque S, Khan N, Pirmohamed M, Clark A T, Nasser S M Management of allergy to penicillins and other beta-lactams. Clin Exp Allergy 2015; 45(2): 300–27.
  • Mor A, Frøslev T, Thomsen R W, Oteri A, Rijnbeek P, Schink T, Garbe E, Pecchioli S, Innocenti F, Bezemer I, Poluzzi E, Sturkenboom M C, Trifirò G, Søgaard M. Antibiotic use varies substantially among adults: a cross-national study from five European Countries in the ARITMO project. Infection 2015; 43(4): 453–72.
  • Namba R S, Paxton L, C Fithian D, Lou Stone M. Obesity and perioperative morbidity in total hip and total knee arthroplasty patients. J Arthroplasty 2005; 20(7 Suppl 3): 46–50.
  • Namba R S, Inacio M C, Paxton E W. Risk factors associated with deep surgical site infections after primary total knee arthroplasty. J Bone Joint Surg Am 2013; 95(9): 775–82.
  • Park M A, Koch C A, Klemawesch P, Joshi A, Li J T. Increased adverse drug reactions to cephalosporins in penicillin allergy patients with positive penicillin skin test. Int Arch Allergy Immunol 2010; 153(3): 268–73.
  • Parvizi J, Zmistowski B, Berbari EF, Bauer TW, Springer BD, Della Valle CJ, Garvin KL, Mont MA, Wongworawat MD, Zalavras CG. New definition for periprosthetic joint infection: from the Workgroup of the Musculoskeletal Infection Society. Clin Orthop Relat Res 2011; 469(11): 2992–4.
  • Parvizi J, Gehrke T, Franklin B. Proceedings of the International Consensus Meeting on Periprosthetic Joint Infection. 2013.
  • Pichichero M E, Casey J R. Safe use of selected cephalosporins in penicillin-allergic patients : A meta-analysis. Otolaryngol Head Neck Surg 2007; 136(3): 340–7.
  • Ponce B, Raines B T, Reed R D, Vick C, Richman J, Hawn M. Surgical site infection after arthroplasty: comparative effectiveness of prophylactic antibiotics. J Bone Joint Surg Am 2014; 96(12): 970–7.
  • Pool C, Kass J, Spivack J, Nahumi N, Khan M, Babus L, Teng M S, Genden E M, Miles B A. Increased surgical site infection rates following clindamycin use in head and neck free tissue transfer. Otolaryngol Head Neck Surg 2016; 154(2): 272–8.
  • Robertsson O, Ranstam J. No bias of ignored bilaterality when analysing the revision risk of knee prostheses: analysis of a population based sample of 44,590 patients with 55,298 knee prostheses from the national Swedish Knee Arthroplasty Register. BMC Musculoskelet Disord 2003; 4: 1.
  • Robertsson O, Ranstam J, Sundberg M, W-Dahl A, Lidgren L. The Swedish Knee Arthroplasty Register: a review. Bone Joint Res 2014; 3(7): 217–22.
  • Romano A, Gaeta F, Arribas Poves M F, Valluzzi R L. Cross-reactivity among beta-lactams. Curr Allergy Asthma Rep 2016; 16(3): 24.
  • SBU. Antibiotikaprofylax vid kirurgiska ingrepp. Swedish Agency for Health Technology Assessment and Assessment of Social Services. Stockholm; 2010. Available from: http://www.sbu.se/200
  • Singh J, Politis A, Loucks L, Hedden D R, Bohm E R. Trends in revision hip and knee arthroplasty observations after implementation of a regional joint replacement registry. Can J Surg 2016; 59(5): 304–10.
  • Solensky R. Hypersensitivity reactions to beta-lactam antibiotics. Clin Rev Allergy Immunol. 2003; 24(3): 201–20.
  • Stefánsdóttir A, Erichsen Andersson A, Höglund Karlsson I, Staaf A, Stenmark S, Tammelin A. Infektionsförebyggande arbete kan aldrig avslutas. Lakartidningen. 2014. Available from: www.lakartidningen.se/Opinion/Debatt/2014/08/Nationellt-projekt-for-att-halvera-antalet-protesrelaterade-infektioner/
  • Terico A T, Gallagher J C. Beta-lactam hypersensitivity and cross-reactivity. J Pharm Pract 2014; 27(6): 530–44.
  • The Public Health Agency of Sweden. 2015 Swedres | Svarm: Consumption of antibiotics and occurrence of antibiotic resistance in Sweden [Internet]. 2015. Available from; www.sva.se/globalassets/redesign2011/pdf/om_sva/publikationer/swedres_svarm2015.pdf
  • The Swedish Knee Arthroplasty Register. Annual report 2016. Lund; 2016.
  • Trampuz A, Zimmerli W. Antimicrobial agents in orthopaedic surgery: Prophylaxis and treatment. Drugs 2006; 66(8):1089–105.
  • Voigt J, Mosier M. Systematic review and meta-analysis of randomized controlled trials of antibiotics and antiseptics for preventing infection in people receiving primary total hip and knee prostheses. Antimicrob Agents Chemother 2015; 59(11): 6696–707.
  • Witsø E. The rate of prosthetic joint infection is underestimated in the arthroplasty registers. Acta Orthop 2015; 86 (3): 277–8.

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